检索结果-南通市图书馆

Prognostic value of dynamic electroencephalogram in comatose patients with different diseased regions

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2007年第7期2卷 421-424页

作者： Huapin Huang Chunhui Che An Zheng Xiaoyun zhuang fang Jiang Nan Liu Department of Neurology Union Hospital of Fujian Medical University Fuzhou 350001 Fujian Province China

BACKGROUND： It has proved that dynamic electroencephalogram （EEG） is definite in judging the outcome of ischemic hypoxic comatose patients, EEG is more sensitive to the cortical affection, but not sensitive to the subcortical and brainstem affections, thus it is necessary to clarify the indications of this technique in the clinical application.OBJECTIVE： To observe and compare the prognostic value of dynamic EEG and Glasgow coma score in comatose patients with different diseased region.DESIGN： A clinical case-controlled observation.SETTING： Union Hospital of Fujian Medical University.PARTICIPANTS： Sixty-eight comatose patients were selected from the Union Hospital affiliated to Fujian Medical University from June 1998 to January 2005. The diseased regions were identified using cranial CT （n =43） or MR （n =25）. According to different primarily diseased regions, the comatose patients were divided into two groups： ① brainstem affection group （n =23）： 13 males and 10 females, 14 - 62 years of age; ②diffuse cortical affection group （n =45）： 28 males and 17 females, 23 - 75 years of age.METHODS： The dynamic EEG and Glasgow coma score were examined in the 45 comatose patients with primarily cortical affection and 22 comatose patients with primarily brainstem affection at acute phase. The patients were followed-up for 3 months to observe the outcome, The termination of outcome judgment was 3 months after attack or the death. The clinical outcome was classified as complete rehabilitation, survived with disability, death or vegetative state. Correlations of dynamic EEG and Glasgow coma score with the outcome of patients were analyzed. The correlations of dynamic EEG grades and Glasgow coma scores with the outcome were analyzed, and the prognostic value of dynamic EEG grades was compared between the two groups.MAIN OUTCOME MEASURES： ① Correlations of dynamic EEG and Glasgow coma score with the outcome of patients; ② Comparison of the prognostic value of dynamic EEG

关键词： dynamic electroencephalogram brainstem infarction coma outcome cerebral cortex

Hyper-crosslinked Conjugated Microporous Polymers with Increased Micropores Promotes Confining Polymerization for Electromagnetic Absorption Application

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Polymer Science 2023年第8期41卷 1305-1316,I0011页

作者： Hao Chen fang-Yuan Chu Hai-Yan zhuang Lu Wang Zhi-Min Ye Wei Dong Zhi-Peng Xie A-Ming Xie School of Mechanical Engineering Nanjing University of Science&TechnologyNanjing 210094China State Key Laboratory for Marine Corrosion and Protection Luoyang Ship Material Research Institute(LSMRI)Xiamen 361100China School of Chemistry and Chemical Engineering Nanjing University of Science&TechnologyNanjing 210094China

Conjugated microporous polymers have excellent skeleton structures but poor electrical conductivity limits their applications in microwave *** solve this problem,a strategy of molecular expansion and confining polymerization is proposed in this work to synthesize conductive hyper-crosslinked conjugated microporous *** topology of the conjugated microporous polymer is changed into a three-dimensional skeleton structure with high specific surface area by using molecular expansion technique,and the controlled growth of polypyrrole in the channel constructs a unique network *** balance of excellent composite backbone structure,proper conductivity,attenuation capability and impedance matching enable the material to exhibit electromagnetic wave absorption *** a result,with low filler loading of 10 wt%,a strongest reflection loss of-52.68 d B and a maximum effective bandwidth of 5.76 ***,CST simulations of the radar scattering cross section have been carried out to verify the excellent material *** study provides new concepts for new conductive polymers and broadens the application of hyper-crosslinked conjugated microporous polymer in the field of electromagnetic wave absorption.

关键词： Hyper-crosslinked conjugated microporous polymer Electromagnetic wave absorbing Molecular expansion Polypyrrole

红景天苷对类风湿关节炎患者血清脯氨酸羟化酶2及蛋白磷酸酯酶2A和丝裂原活化蛋白激酶表达水平的影响

在线全文

学校读者我要写书评

暂无评论

中国医药 2024年第7期19卷 1061-1065页

作者：李琴朱光昭庄志毅星媛严婕方璐青海省中医院风湿科西宁810000 青海大学研究生院西宁810000

目的分析红景天苷对类风湿关节炎(RA)患者血清脯氨酸羟化酶2(PHD2)及蛋白磷酸酯酶2A(PP2A)和丝裂原活化蛋白激酶(MAPK)表达水平的影响。方法选取青海省中医院2022年12月至2023年7月收治的RA患者96例。采用随机数字表法分为对照组和观察... 详细信息

目的分析红景天苷对类风湿关节炎(RA)患者血清脯氨酸羟化酶2(PHD2)及蛋白磷酸酯酶2A(PP2A)和丝裂原活化蛋白激酶(MAPK)表达水平的影响。方法选取青海省中医院2022年12月至2023年7月收治的RA患者96例。采用随机数字表法分为对照组和观察组,各48例。对照组采用常规西医治疗,观察组在常规西医治疗的同时予以红景天苷治疗,2组均治疗3个月。比较治疗前后2组中医证候评分、临床症状与体征、实验室检查指标[包括红细胞沉降率(ESR)、C反应蛋白(CRP)、类风湿因子(RF)、抗环瓜氨酸肽抗体(anti-CCP)]、临床疗效,健康状况评定量表(HAQ)与28个关节疾病活动度评估(DAS28)评分,血清PHD2、PP2A、MAPK水平与基因表达,不良反应。结果治疗后2组主症、次症评分均低于治疗前且观察组均低于对照组(均P<0.05)。治疗后观察组临床症状与体征均轻于对照组,ESR、CRP、RF和anti-CCP水平均低于对照组(均P<0.05)。观察组总有效率高于对照组[95.8%(46/48)比80.4%(37/46)](P=0.020)。治疗后观察组HAQ与DAS28评分均低于对照组[(5.0±1.0)分比(7.2±1.2)分、(3.1±0.5)分比(4.1±0.7)分](t=9.528、7.444,均P<0.001)。治疗后观察组PHD2、MAPK水平及基因表达均低于对照组,PP2A水平及基因表达均高于对照组,差异均有统计学意义(均P<0.05)。2组不良反应发生率差异无统计学意义(P=0.528)。结论红景天苷治疗RA可增强临床效果、减轻患者症状、改善实验室指标且安全。推测与降低PHD2和MAPK表达、增加PP2A表达有关。

关键词：类风湿关节炎红景天苷脯氨酸羟化酶2 蛋白磷酸酯酶2A 丝裂原活化蛋白激酶

基于图卷积神经网络的线上教育资源群组推荐方法

在线全文

学校读者我要写书评

暂无评论

辽宁大学学报（自然科学版） 2024年第2期51卷 169-178页

作者：周翰逊张硕张昉孔壮壮田思雨王龙郭薇毛艳娥辽宁大学信息学院辽宁沈阳110036 辽宁省交通高等专科学校信息工程系辽宁沈阳110122 菏泽职业学院信息工程系山东菏泽274002 沈阳航空航天大学计算机学院辽宁沈阳110136

线上教育资源推荐方法大部分是面向单个学习者的,然而不少学习活动多以多个学习者构成群组的形式进行.针对上述情况,首先,我们对群组成员间的社交网络进行建模,将学习者信任度、相似度和专业度以及衡量成员之间关系权重的个性度作为特... 详细信息

线上教育资源推荐方法大部分是面向单个学习者的,然而不少学习活动多以多个学习者构成群组的形式进行.针对上述情况,首先,我们对群组成员间的社交网络进行建模,将学习者信任度、相似度和专业度以及衡量成员之间关系权重的个性度作为特征信息,然后通过图卷积神经网络学习聚合邻居信息得到个人偏好.其次,借助偏好融合策略得到群组的最终偏好.最后,按照项目评分,对线上学习群组进行教育资源推荐.实验结果表明,该方法有效提高了线上学习者群组的准确性和满意度.

关键词：群组推荐成员关系图卷积神经网络

Standard Operation Procedure of Percutaneous Endomyocardial Biopsy in Peking Union Medical College Hospital

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Cardiology Discovery 2021年第3期1卷 148-153页

作者： Xiqi Xu zhuang Tian Quan fang Zhi-Cheng Jing Shuyang Zhang Department of Cardiology Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China

Percutaneous endomyocardial biopsy (EMB) is a technique that biopsy samples are obtained using bioptome through peripheral blood vessel. This technique has been used and refined more than 50 years in clinical application. Now EMB has become an important diagnostic tool in the diagnosis of myocarditis and cardiomyopathy. Department of cardiology, Peking Union Medical College Hospital (PUMCH) has performed more than 500 cases of EMB and accumulated abundant practical experience. The clinical practice guideline of percutaneous EMB in PUMCH was also established, including indications, contradictions, operation key points, sample handling and processing, post-procedure monitoring, and treatment strategy for potential complications, etc. Due to the limitation of EMB, cardiologists should collaborate with experts in echocardiography, cardiac magnetic resonance and cardiac pathology to avoid missed diagnosis and misdiagnosis. Cardiologists should pay more attention to the value of EMB and actively perform EMB to improve the diagnosis level for myocarditis and cardiomyopathy in China.

关键词： Myocarditis Cardiomyopathy Endomyocardial biopsy

Genome-wide identification and analysis of cytokinin dehydrogenase/oxidase(CKX) family genes in Brassica oleracea *** their involvement in response to Plasmodiophora brassicae infections

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Horticultural Plant Journal 2022年第1期8卷 68-80页

作者： Mingzhao Zhu Yong Wang Shujin Lu Limei Yang Mu zhuang Yangyong Zhang Honghao Lv Zhiyuan fang Xilin Hou State Key Laboratory of Crop Genetics and Germplasm Enhancement College of HorticultureNanjing Agricultural UniversityNanjing 210095China Key Laboratory of Biology and Genetic Improvement of Horticultural Crops Ministry of AgricultureInstitute of Vegetables and FlowersChinese Academy of Agricultural SciencesBeijing 100081China

Cytokinins are a class of phytohormones that promote cell division and differentiation and are thought to affect plant immunity to multiple ***,a comprehensive analysis of cytokinin dehydrogenase/oxidase(CKX)family genes in cabbage has not been *** this study,a total of 36 CKX genes were identified using a genome-wide search *** analysis classified these genes into three *** were distributed unevenly across nine chromosomes in ***,and 15 of them did not contain any *** results of colinearity analysis showed that 36 CKX gene in Arabidopsis was present in several copies in the Brassica oleracea *** analysis of cisacting elements indicated that all genes possessed at least one stress or hormone responsive cis-acting element.A heatmap of CKX gene expression showed the patterns of expression of these genes in various tissues and *** genes(Bol028363,Bol031036 and Bol018140)were relatively highly expressed in all of the investigated tissues under normal conditions,showing the expression profile of housekeeping ***,the expression patterns of CKX genes in Jingfeng 1 and Xiangan 336 were quite different under the same ***,three genes(Bol020547,Bol028392 and Bol045724)were significantly down-regulated and up-regulated in the susceptible and resistant material,respectively,after inoculation,which may indicate their crucial roles in resistance to clubroot *** results provide insights for better understanding the roles of CKX genes in the ***–*** interaction.

关键词： Brassica oleracea Genome-wide Cytokinin dehydrogenase/oxidase(CKX)genes Clubroot

BDD污水处理电极对染料废水降解脱色的研究

在线全文

学校读者我要写书评

暂无评论

广州化工 2024年第9期52卷 108-113,147页

作者：张天颖万方邹西壮张韬薛喆无锡职业技术学院机械技术学院江苏无锡214122 上海海洋大学工程学院上海200240 张家港市微纳新材料科技有限公司江苏苏州201316

染料废水是典型的高浓度、难降解的有机废水。实验以提高脱色效率及降低降解能耗为目的,依托电化学高级氧化法,利用硼掺杂金刚石薄膜电极对活性艳红X-3B模拟染料废水的降解工艺进行优化研究。实验采用偏压增强热丝化学气相沉积法设备以... 详细信息

染料废水是典型的高浓度、难降解的有机废水。实验以提高脱色效率及降低降解能耗为目的,依托电化学高级氧化法,利用硼掺杂金刚石薄膜电极对活性艳红X-3B模拟染料废水的降解工艺进行优化研究。实验采用偏压增强热丝化学气相沉积法设备以及动态掺硼工艺,以面积40 cm^(2)Ti为衬底,进行BDD薄膜的合成实验。并通过改变电解时的电压、电解质浓度、pH值、支持电解质参数进行脱色工艺研究,最终获得与Ti基BDD电极适配的较优电解参数。

关键词： Ti基BDD电极 HFCVD 染料废水活性艳红X-3B

皖南地区8199例婴幼儿TORCH感染血清学检测结果分析

在线全文

学校读者我要写书评

暂无评论

热带病与寄生虫学 2024年第1期22卷 42-46页

作者：蒋路晴李磊徐梓琛翟蓥庄玲丹付夏方芳王玉萍武其文皖南医学院第一附属医院安徽芜湖241001

目的探讨皖南地区近年来TORCH病原体,即弓形虫(Toxoplasma gondii,TOX)、风疹病毒(rubella virus,RV)、巨细胞病毒(cytomegalovirus,CMV)和单纯疱疹病毒(herpes simplex virus,HSV)在婴幼儿人群的感染状况及流行特点,为儿童相关疾病的预防、诊断和治疗提供参考。方法回顾性分析2016年4月—2023年3月皖南医学院第一附属医院接诊的0~3岁婴幼儿TORCH感染血清IgM和IgG抗体检测结果,并对不同年龄、年份的TORCH阳性率进行比较分析。结果共有8199例0~3岁婴幼儿进行TORCH感染血清学筛查检测,其中男性4631例,女性3568例。婴幼儿TOX、RV、CMV、HSVⅠ和HSVⅡ的IgM抗体阳性率分别为0.11%、0.20%、0.89%、0和0,差异有统计学意义(χ^(2)=100.000,P<0.05);相对应的IgG抗体阳性率分别为10.81%、78.36%、98.32%、82.38%和13.45%,差异有统计学意义(χ^(2)=22828.211,P<0.05)。不同年龄组比较,婴儿组CMV-IgM阳性率(11.90%)高于新生儿组(0.20%)和幼儿组(1.40%),差异均有统计学意义(χ^(2)=672.920、20.569,P均<0.017);新生儿组TOX-IgG、RV-IgG、CMV-IgG、HSVⅠ-IgG和HSVⅡ-IgG阳性率(11.01%、79.88%、98.76%、85.35%、13.72%)高于婴儿组(6.71%、49.35%、96.54%、50.87%、9.74%),差异均有统计学意义(χ^(2)=8.369、237.184、16.033、373.121、5.902,P均<0.017)。不同年份比较,CMV-IgM阳性率2016年最高,各年差异有统计学意义(χ^(2)=15.816,P<0.05);不同年份TOX-IgG、RV-Ig G、CMV-IgG、HSVⅠ-IgG、HSVⅡ-IgG阳性率差异均有统计学意义(χ^(2)=216.002、90.545、37.047、59.527、57.623,P均<0.05)。结论皖南地区0~3岁婴幼儿中TORCH既往感染以CMV、HSVⅠ和RV为主,现症感染主要为CMV,对婴幼儿进行TORCH感染筛查检测对于保护儿童的健康至关重要。此外,应做好妊娠规划、产前保健和筛查,预防TORCH感染。

关键词： TORCH感染婴幼儿抗体检测皖南地区

Alpha-fetoprotein and 18F-FDG standard uptake value predict tumor recurrence after liver transplantation for hepatocellular carcinoma with portal vein tumor thrombosis:Preliminary experience

在线全文

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2020年第3期19卷 229-234页

作者： Zhe Yang fang-Zhou Luo Shuo Wang Jan Lerut Li zhuang Qi-Yong Li Xiao Xu Shu-Sen Zheng Department of Hepatobiliary and Pancreatic Surgery Department of Liver TransplantationShulan(Hangzhou)HospitalZhejiang Shuren University School of MedicineHangzhouChina Division of Hepatobiliary Pancreatic Surgery First Affiliated HospitalZhejiang University School of MedicineHangzhouChina National Clinical Research Center of Infectious Diseases HangzhouChina Starzl Unit of Abdominal Transplantation University Hospitals Saint LucUniversitécatholique LouvainBrusselsBelgium

Background:Portal vein tumor thrombosis(PVTT)is regarded as a contraindication for liver transplantation(LT)in hepatocellular carcinoma(HCC).However,some of these patients may have a favorable prognosis after *** this study,we evaluated the biological behavior of HCC with PVTT using tumor biomarker(alpha-fetoprotein,AFP)and 18 F-FDG positron emission tomography(tumor standard uptake value)to identify a subset of patients who may be suitable for ***:Seventy-five HCC-PVTT liver recipients transplanted during February 2016 and June 2018 were *** pre-transplant prognostic factors were identified by univariate and multivariate *** status was identified following Vp classification(Vp1-Vp4).Results:Three-year recurrence-free survival and overall survival rates were 40%and 65.4%in Vp2-Vp3 PVTT patients,21.4%and 30.6%in Vp4 PVTT patients(P8 cm,pretransplant AFP level>1000 ng/m L and intrahepatic tumor maximal standard uptake value(SUVmaxtumor>5)were independent risk factors for HCC recurrence and overall survival after LT in Vp2-3 PVTT *** risk patients were defined as total tumor diameter≤8 cm;or if total tumor diameter more than 8 cm,with both pre-transplant AFP level less than 1000 ng/m L and intrahepatic tumor SUVmax less than 5,***-two Vp2-3 PVTT HCC patients(46.8%)were identified as low risk patients,and their 3-year recurrence-free and overall survival rates were 67.6%and 95.2%,***:Patients with segmental or lobar PVTT and biologically favorable tumors defined by AFP and 18 F-FDG SUVmax might be suitable for LT.

关键词： Hepatocellular carcinoma Liver transplantation Portal vein tumor thrombosis Alpha-fetoprotein Standard uptake value