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Experimental study on wax deposition of highly paraffinic oil in intermittent gas-oil flow in pipelines

Petroleum Science 2024年第3期21卷 2080-2088页

作者： Chuan-Shuo Wang Qian-Li Ma Xiao-fang lv Jie Zhang Yang Liu Shi-Dong Zhou Jiangsu Key Laboratory of Oil and Gas Storage and Transportation Technology Changzhou UniversityChangzhou213164JiangsuPR China Hade Oil and Gas Development Department Tarim Oilfield BranchKorla841000XinjiangPR China

Oil-gas two phase wax deposition is a fairly common and open-ended question in flow assurance of multiphase transportation *** paper investigated the two main aspects of oil-gas two phase wax deposition layer:apparent thickness and crystal structure characteristics.A typical highly paraffinic oil in Bohai Sea,China,was used as the experimental material to investigate the wax deposition thickness in oil-gas two phase under the influence of different oil temperatures,superficial gas/liquid phase velocities and gas-oil ratios by using multiphase flow loop experimental *** as in the classical theory of wax molecular diffusion,it showed that wax deposition thickness of oil-gas two phase increased with increasing oil *** of the impact of different superficial phase velocities found that the actual liquid flow heat transfer and shear stripping was the gas phase dominant mechanisms determining wax deposit *** addition,the crystal structure of the wax deposition layer was characterized with the help of small-angle X-ray scattering(SAXS)for different circumferential positions,flow rates and gas-oil *** bottom deposition layer had a complex crystal structure and high hardness,which were subject to change over flow rate ***,the SAXS results provided evidence that the indirect effect of the actual liquid velocity modified by the gas phase was the main *** study of the effect of gas phase on the wax deposition of oil-gas two phase will help shed light onto the mechanism by which this important process *** findings address a very urgent need in the field of wax deposition of highly paraffinic oil to understand the flow security of oilgas two phase that occurs easily in multiphase field pipelines.

关键词： Oil-gas two phase Highly paraffinic oil Wax deposition SAXS

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Knowledge Graph Analysis of International Chinese Language Textbooks Based on CiteSpace

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Journal of Contemporary Educational Research 2024年第4期8卷 163-175页

作者： fang lv Guangxi Normal University Guilin 541004China

Drawing upon relevant papers from Chinese core journals and CSSCI source journals in the CNKI China Academic Journals Full-Text Database spanning from 1992 to 2023,this study utilizes CiteSpace as a research tool to visually analyze the knowledge graph structure of research on international Chinese language textbooks in *** study maps out the publication timeline,authors,institutions,collaborative networks,and keywords pertaining to research on international Chinese language *** findings indicate that research on international Chinese language textbooks commenced early and continues to maintain a certain level of research interest,yet lacks sufficient research *** institutions predominantly reside in universities and publishing groups specializing in language or education,with collaboration between institutions being relatively ***-frequency keywords in recent research on international Chinese language textbooks include“Chinese language textbooks for the Foreigners,”“Chinese language textbooks,”“Teaching Chinese Language for the Foreigners,”“Textbook compilation,”“International Chinese Language Education and Localization,”which reflect a diversified research perspective with interdisciplinary *** research priorities encompass research on localization,customization of textbooks,and evaluation of textbooks which represent forefront directions of research.

关键词： International Chinese language textbooks CiteSpace Knowledge graph China

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基因编辑技术的人文审视——基于马克思技术观的人学向度

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科技创业月刊 2024年第3期37卷 123-127页

作者：吕芳华南理工大学马克思主义学院广东广州510000

作为现代生命技术领域的一项颠覆性的技术发明,基因编辑技术能够通过技术手段改写人类基因,这对当代人与技术关系提出了新课题。技术观构成马克思哲学思想的重要理论分支,马克思在对技术观的阐发中揭示了技术与人的存在方式、人的生存... 详细信息

作为现代生命技术领域的一项颠覆性的技术发明,基因编辑技术能够通过技术手段改写人类基因,这对当代人与技术关系提出了新课题。技术观构成马克思哲学思想的重要理论分支,马克思在对技术观的阐发中揭示了技术与人的存在方式、人的生存境遇和人的全面发展的相互联结关系,使得技术观呈现鲜明的人学向度。从马克思技术观的人学向度审视基因编辑技术,需要分析基因编辑技术与人的存在方式和人的生存境遇的新状况,结合基因编辑技术引发的人文挑战提出基因编辑技术的优化理路在于追求和谐共生、克服技术异化、协调人技关系3个维度,进而得以实现人的自由全面发展的技术价值旨归。

关键词：马克思技术观基因编辑技术人学向度科技伦理

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Human-like adrenal features in Chinese tree shrews revealed by multi-omics analysis of adrenal cell populations and steroid synthesis

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Zoological Research 2024年第3期45卷 617-632页

作者： Jing-Hang Jiang Yi-Fu Wang Jie Zheng Yi-Ming Lei Zhong-Yuan Chen Yi Guo Ya-Jie Guo Bing-Qian Guo Yu-fang lv Hong-Hong Wang Juan-Juan Xie Yi-Xuan Liu Ting-Wei Jin Bi-Qi Li Xiao-Shu Zhu Yong-Hua Jiang Zeng-Nan Mo Center for Genomic and Personalized Medicine Guangxi Collaborative Innovation Center for Genomic and Personalized MedicineGuangxi Key Laboratory for Genomic and Personalized MedicineGuangxi Medical UniversityNanningGuangxi 530021China Department of Urology First Affiliated Hospital of Guangxi Medical UniversityNanningGuangxi 530021China Reproductive Medicine Center Jingmen People’s HospitalJingChu University of Technology Affiliated Central HospitalJingmenHubei 448000China School of Computer Science and Engineering Yulin Normal UniversityYulinGuangxi 537000China Collaborative Innovation Centre of Regenerative Medicine and Medical BioResource Development and Application Co-constructed by the Province and Ministry Guangxi Medical UniversityNanningGuangxi 530021China Department of Pathology Second Affiliated Hospital of Guangxi Medical UniversityNanningGuangxi 530007China Department of Obstetrics and Gynecology Second Affiliated Hospital of Guangxi Medical UniversityNanningGuangxi 530007China

The Chinese tree shrew(Tupaia belangeri chinensis)has emerged as a promising model for investigating adrenal steroid synthesis,but it is unclear whether the same cells produce steroid hormones and whether their production is regulated in the same way as in ***,we comprehensively mapped the cell types and pathways of steroid metabolism in the adrenal gland of Chinese tree shrews using single-cell RNA sequencing,spatial transcriptome analysis,mass spectrometry,and *** compared the transcriptomes of various adrenal cell types across tree shrews,humans,macaques,and *** showed that tree shrew adrenal glands expressed many of the same key enzymes for steroid synthesis as humans,including CYP11B2,CYP11B1,CYB5A,and *** analysis confirmed the production of aldosterone,cortisol,and dehydroepiandrosterone but not dehydroepiandrosterone sulfate in the tree shrew adrenal ***,genes in adrenal cell types in tree shrews were correlated with genetic risk factors for polycystic ovary syndrome,primary aldosteronism,hypertension,and related disorders in humans based on genome-wide association ***,this study suggests that the adrenal glands of Chinese tree shrews may consist of closely related cell populations with functional similarity to those of the human adrenal *** comprehensive results(publicly available at http://***:16245/scAGMap/)should facilitate the advancement of this animal model for the investigation of adrenal gland disorders.

关键词： Tree shrew Adrenal gland Dehydroepiandrosterone Genome-wide association studies Disease model

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不同胆囊入路腹腔镜胆囊切除术治疗胆囊结石合并慢性胆囊炎患者疗效

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四川生理科学杂志 2024年第3期46卷 598-600页

作者：陈磊逵芳芳吕方南阳市中心医院普外微创外科河南南阳473000

目的:探究不同胆囊入路腹腔镜胆囊切除术对胆囊结石合并慢性胆囊炎患者的疗效.方法:选取2021年1月1日至2023年1月31日在本院治疗的胆囊结石伴慢性胆囊炎患者98例作为研究对象,采用随机抽签法分为对照组和实验组,每组各49例.对照组采用... 详细信息

目的:探究不同胆囊入路腹腔镜胆囊切除术对胆囊结石合并慢性胆囊炎患者的疗效.方法:选取2021年1月1日至2023年1月31日在本院治疗的胆囊结石伴慢性胆囊炎患者98例作为研究对象,采用随机抽签法分为对照组和实验组,每组各49例.对照组采用胆囊前三角解剖入路,实验组采用胆囊后三角解剖入路,分析比较两组的手术相关指标、炎性因子和免疫功能.结果:与对照组相比,实验组的手术时间、术中出血量、胃肠功能恢复时间,住院时间均显著降低(P<0.05).术后3 d,两组研究对象的白细胞介素-6(Interleukin-6,IL-6)、白细胞介素-8(Interleukin-8,IL-8)、肿瘤坏死因子-α(Tumor necrosis factor-α,TNF-α)、C-反应蛋白(C-reactive protein,CRP)水平均显著降低,且实验组比对照组降低得更为显著(P<0.05).术后3 d,两组的血清CD4+和CD8+水平均显著降低,但实验组降低的幅度显著低于对照组(P<0.05).结论:采用后三角解剖入路行腹腔镜胆囊切除术治疗胆囊结石合并慢性胆囊炎,能降低患者外科创伤程度,缩短康复时间,减轻机体的炎症反应.

关键词：腹腔镜胆囊切除手术胆囊结石慢性胆囊炎疗效

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基于混合威布尔模型的智能电能表可靠性评价方法

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电测与仪表 2024年第4期61卷 198-205页

作者：黄瑞刘小平刘谋海吕芳谢雄高云鹏国网湖南省电力有限公司长沙410004 湖南大学长沙410082

针对当前智能电能表故障类型多样、可靠性评价单一的问题,提出基于混合威布尔模型的可靠性评价方法。论文基于智能电能表各单元串联关系和故障事件进行故障类型分类,利用最小二乘法推算各单元故障类型的尺度与形状参数,结合中位秩与平... 详细信息

针对当前智能电能表故障类型多样、可靠性评价单一的问题,提出基于混合威布尔模型的可靠性评价方法。论文基于智能电能表各单元串联关系和故障事件进行故障类型分类,利用最小二乘法推算各单元故障类型的尺度与形状参数,结合中位秩与平均秩次计算智能电能表累计失效概率提高模型准确度,并通过熵权法计算各故障类型对整表可靠度影响的权重系数,据此建立基于混合威布尔模型的智能电能表可靠性评价方法。实例结果表明,提出的方法在各类故障类型下均能准确得到智能电能表可靠度评估,并能准确获得智能电能表单元模块的可靠度,与现有方法相比,文中方法不需大量先验知识,且实现简单、准确度更高。

关键词：智能电能表混合威布尔模型熵权法故障类型可靠性评价

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联合国可持续发展理念下北京冬奥遗产可持续发展研究

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体育学刊 2024年第1期31卷 50-56页

作者：孙葆丽高泳李圣鑫叶凡希赵月赵艺桦吕方北京体育大学冬奥文化研究中心北京100084 河南科技学院体育学院河南新乡453003 北京体育大学管理学院北京100084 北京体育大学中国奥林匹克高等研究院北京100084 北京体育大学竞技体育学院北京100084 中国地质大学(北京)体育部北京100083 西安体育学院研究生部陕西西安710068

运用文献资料法与逻辑分析法,探讨联合国可持续发展理念及其在北京冬奥遗产可持续发展中的理论意义,并在此基础上探索北京冬奥遗产可持续发展内涵和赛后发展原则。研究认为:联合国可持续发展理念为北京冬奥遗产的可持续发展提供有益借鉴... 详细信息

运用文献资料法与逻辑分析法,探讨联合国可持续发展理念及其在北京冬奥遗产可持续发展中的理论意义,并在此基础上探索北京冬奥遗产可持续发展内涵和赛后发展原则。研究认为:联合国可持续发展理念为北京冬奥遗产的可持续发展提供有益借鉴,对北京冬奥遗产明晰自身经济、社会与环境三者系统的发展本质、平衡的发展向度、统一的发展愿景和关联的发展效应具有一定的参考意义。基于此,研究将北京冬奥遗产可持续发展内涵总结为“冬奥遗产与生态环境共容”“冬奥遗产与社会发展共融”以及“冬奥遗产与经济发展共荣”,同时提出以人为本、协调共治、共建、共享和循序渐进4项赛后可持续发展原则,以期为北京冬奥遗产的赛后传承与可持续发展提供理论参考。

关键词：奥林匹克运动北京冬奥会可持续发展冬奥遗产联合国

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Mechanical intestinal obstruction due to isolated diffuse venous malformations in the gastrointestinal tract: A case report and review of literature

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World Journal of Clinical Cases 2020年第1期8卷 157-167页

作者： Han-Bo Li Jing-fang lv Ning Lu Zong-Shun lv Department of General Surgery Tianjin General Surgery InstituteTianjin Medical University General HospitalTianjin 300052China Department of Plastic Surgery Plastic Surgery HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100144China Department of Gastroenterology Tianjin Medical University General HospitalTianjin 300052China

BACKGROUND Isolated gastrointestinal venous malformations(GIVMs)are extremely rare congenital developmental abnormalities of the venous *** of their asymptomatic nature,the diagnosis is often quite ***,as symptomatic GIVMs have nonspecific clinical manifestations,misdiagnosis is very ***,we report a case of isolated diffuse GIVMs inducing mechanical intestinal obstruction.A literature review was also conducted to summarize clinical features,diagnostic points,treatment selections and differential diagnosis in order that doctors may have a comprehensive understanding of this *** SUMMARY A 50-year-old man presented with recurrent painless gastrointestinal bleeding for two months and failure to pass flatus and defecate with nausea and vomiting for ten *** rectal examination found bright red blood and soft nodular masses 3 cm above the anal *** tomography showed that part of the descending colon and rectosigmoid colon was thickened with phleboliths in the intestinal *** exhibited bluish and reddish multinodular submucosal masses and flat submucosal serpentine *** ultrasonography showed anechoic cystic spaces within intestinal *** lesions were initially thought to be isolated VMs involving part of the descending colon and rectosigmoid *** subtotal proctocolectomy,pullthrough transection and coloanal anastomosis and ileostomy were *** revealed intact mucosa and dilated,thin-walled blood vessels in the submucosa,muscularis,and serosa involving the entire *** patient recovered with complete symptomatic relief during the 52-mo follow-up *** The diagnosis of isolated GIVMs is *** information presented here is significant for the diagnosis and management of symptoms.

关键词： Case report Isolated gastrointestinal venous malformations Mechanical intestinal obstruction Pull-through transection and coloanal anastomosis Diagnosis Treatment

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Iodine catalyzed synthesis of the chromene derivatives in one-pot

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Chinese Chemical Letters 2012年第12期23卷 1347-1351页

作者： Li Yan Zeng Mei fang lv Chun Cai Chemical Engineering College Nanjing University of Science & Technology

Iodine catalyzed one-pot reactions of salicylaldehyde and dimolecular 1H-indene-l,3（2H）-dione, barbituric acids, 4-hydro- xycoumarin, or 4-hydroxy-6-methylpyran-2-one were performed and provided a rapid, convenient and general approach to synthesize the chromene derivatives. 2-（11-Oxo-10,11-dihydroindeno[1,2-b]chromen-10-yl）-lH-indene-1,3（2H）-diones P1-P4 and 10-（4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl）-3-methylpyrano[4,3-b]chromen-1（1OH）-ones P8-P9 were unprecedentedly prepared and structurally identified by NMR and Mass. The confirmation of structure by single crystal X-ray crystallography is reported for P3.

关键词： Chromene Iodine MCRs Salicylaldehyde 1H-Indene-1,3(2H)-dion

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癫痫共患焦虑和抑郁现状及危险因素分析

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疾病预防控制通报 2024年第4期39卷 24-28页

作者：吕芳马晓东李铿甘肃省疾病预防控制中心兰州730000

目的调查癫痫患者共患焦虑抑郁现状,并分析相关危险因素,为癫痫患者焦虑和抑郁的诊治和干预提供思路。方法采用Zung氏焦虑自评量表(SAS)和抑郁自评量表(SDS)对335例确诊癫痫患者进行调查,同时结合患者的临床表现及精神心理疾病诊断标准... 详细信息

目的调查癫痫患者共患焦虑抑郁现状,并分析相关危险因素,为癫痫患者焦虑和抑郁的诊治和干预提供思路。方法采用Zung氏焦虑自评量表(SAS)和抑郁自评量表(SDS)对335例确诊癫痫患者进行调查,同时结合患者的临床表现及精神心理疾病诊断标准明确诊断。结果335例癫痫患者焦虑共患率为58.5%,其中轻度、中度和重度共患率分别为36.1%、18.8%和3.6%,不同婚姻状况(χ^(2)=6.375,P=0.041)、职业(χ^(2)=31.963,P=0.000)、经济状况(χ^(2)=22.375,P=0.001)、教育程度(χ^(2)=9.224,P=0.026)、首发年龄(χ^(2)=6.545,P=0.038)和病程(χ^(2)=21.874,P=0.001)的焦虑共患率差异有统计学意义;抑郁共患率为58.8%,其中轻度、中度和重度共患率分别为29.9%、17.0%和11.9%,不同职业(χ^(2)=17.687,P=0.000)、经济状况(χ^(2)=6.728,P=0.035)和病程(χ^(2)=12.521,P=0.002)的抑郁共患率差异有统计学意义。Logistic回归分析显示,教育程度、首发年龄、职业、经济状况和病程是共患心理疾病的独立危险因素。教育程度高、经济状况好、心理疾病共患率低,首发年龄越大、病程越长,心理疾病共患率越高。结论癫痫患者合并焦虑和抑郁的患病率较高,直接影响其生活质量,应及早开展焦虑和抑郁的筛查评估并采取针对性干预措施。

关键词：癫痫焦虑抑郁危险因素

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