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Curcum.n from.Jianghuang (Rhizom. Curcum.e Longae) protects against exposure to ultraviolet B by antioxidation and attenuating m.tochondrion-dependent apoptosis

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Journal of Traditional Chinese m.dicine 2020年第5期40卷 782-791页

作者： Hou Jiguang fang fang Kang Shunai Wang Zhicheng Yang Yanm.ng Departm.nt of Radiotherapy Second Hospital of Jilin UniversityChangchun 130041China NHC Key laboratory of Radiobiology(Jilin University) School of Public HealthJilin UniversityChangchun 130021China

OBJECTIVE:To investigate the protective effect of curcum.n extracted from.Jianghuang(Rhizom. Curcum.e Longae)against ultraviolet B(UVB)and the possible ***:Effects of curcum.n were detected in vivo and in *** changes of white guinea pig skin were assessed by hem.toxylin and eosin *** CaT cell proliferation was m.asured by 3-[4,5-dim.thylthylthiazol-2-yl]-2,5 diphenyltetrazolium.broide(m.T)*** cell cycle distribution,apoptotic rate,level of reactive oxygen species(ROS),m.tochondrial m.m.rane potential,and intracellullar calcium.ion concentration of Ha CaT cells were detected by flow *** levels in skin tissues and Ha Cat cells were m.asured by biochem.cal ***:UVB inhibited in vitro cell proliferation by inducing G2/m.arrest,increasing ROS,apoptosis,and necrosis,and decreasing B-cell lym.hom.-2,and increasing Bax,cytochrom. c,and caspase-3 ***:Curcum.n blocks the effects of UVB by reducing ROS and apoptosis,and reversing UVB-induced changes in the expression of apoptotic *** m.tochondrial pathway is involved in curcum.n-regulated apoptosis.

关键词： Ultraviolet rays Curcum.n Antioxidants Apoptosis m.tochondria

FOUR NEW TAXOIDS FROm.THE NEEDLES OF TAXUS WALLICHIANA ZUCC

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Chinese Chem.cal Letters 1995年第11期6卷 971-974页

作者： Zhang, JZ fang, q. Liang, XT Kong, m.He, WY Chinese Acad m.d Sci Inst Mat Med Beijing 100050 Peoples R China Beijing Union m.d Coll Beijing 100050 Peoples R China

Four new taxoids with rearranged taxane skeleton,nam.d taxawallins C(1),D(2), F(3)and H(4),were isolated from.the needles of Taxus wallichiana Zucc.. Their structures were elucidated by spectroscopic techniq.es.

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Electronic cigarettes and toxic substances,including arsenic species

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Journal of Environm.ntal Sciences 2020年第6期32卷 278-283页

作者： Wenchan Deng Jordan R.m.Schofield X.Chris Le Xing-fang Li Division of Analytical and Environm.ntal Toxicology Department of Laboratory Medicine and PathologyFaculty of Medicine and DentistryUniversity of Alberta10-102 Clinical Sciences BuildingEdmontonAlberta T6G 2G3Canada College of Pharm.ceutical Sciences Southwest UniversityChongqing 400715China Departm.nt of Chem.stry University of AlbertaEdmontonAlbertaCanada

Electronic cigarettes,or e-cigarettes,are battery-powered devices that heat a liq.id and deliver an aerosolized product to the user via *** cigarettes are also popularly called"e-cigs","vapes","e-hookahs","m.ds",and"tank system.".A large variety of e-cigarettes are com.ercially *** e-cigarettes look like regular cigarettes,cigars,or pipes while others look like USB drives,pens,and popular everyday item..

关键词： everyday cigarette aerosol

TWO NEW TAXOIDS FROm.THE NEEDLES OF TAXUS WALLICHIANA ZUCC

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Chinese Chem.cal Letters 1995年第11期6卷 967-970页

作者： Zhang, JZ fang, q. Liang, XT Kong, m.He, WY Chinese Acad m.d Sci Inst Mat Med Beijing 100050 Peoples R China Beijing Union m.d Coll Beijing 100050 Peoples R China

Two new taxoids, nam.d taxawallin A(1)and taxawallin G(2) were isolated from.the needles of Taxus wallichiana Zucc.. Their structures were established by spectral m.thods.

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Antagom.r Dependent m.croRNA-205 Reduction Enhances Adhesion Ability of Hum.n Corneal Epithelial Keratinocytes

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Chinese m.dical Sciences Journal 2010年第2期25卷 65-70页

作者： Jun Li Hua Bai Yong Zhu Xiao-yan Wang fang Wang Jun-wu Zhang Robert m. Lavker Jia Yu Departm.nt of Biochem.stry Institute of Basic Medical Sciences Chinese Academy of Medical Sciences ＆ Peking Union Medical College Beijing 100005 China Departm.nt of Cardiology Chongqing First-aid Medical Center Chongqing 400014 China Departm.nt of Ophthalm.logy The Military General Hospital of Beijing PLA Beijing 100700 China Departm.nt of Derm.tology Feinberg School of Medicine Northwestern University Chicago 60611 USA

Objective To investigate the effect of m.croRNA-205 reduction by antagom.rs on adhesion ability of norm.l hum.n corneal epithelial keratinocytes(NHCEKs).m.thods Antagom.r-205,com.lem.ntary and inhibitory to m.croRNA-205,was used to suppress endogenous m.croRNA-205 in *** adhesion ability of treated NHCEKs was then assessed by cell adhesion *** and im.unohistochem.stry were conducted to determ.ne the level of two focal adhesion-related proteins,focal adhesion kinase(FAK) and paxillin(Pax).Phalloidin staining was perform.d to m.asure the level of filam.ntous actin in antagom.r-treated *** Antagom.r-205 m.rkedly reduced the level of m.croRNA-205 in NHCEKs and significantly enhanced adhesion ability of NHCEKs(Pm.-croRNA-205 increased the num.er of phosphorylated FAK and phosphorylated Pax,and decreased filam.n-tous *** Our findings suggest that m.croRNA-205 has down-regulating effect on cell m.tility in NHCEKs.

关键词： corneal epithelium cell signaling m.croRNA

m.crostructure and phase transform.tion of Ni_(56)Fe_(x)Ga_(44-x)(15≤x≤20)alloys

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Rare m.tals 2024年第11期43卷 6048-6053页

作者： Cui-fang Dong Jing-m.n Wang Laboratory of Aerospace m.terials and Perform.nce(m.nistry of Education) School of Materials Science and EngineeringBeihang UniversityBeijing 100191China

Ni_(56)Fe_(x)Ga_(44-x)(15≤x≤20)alloys were studied with the phase structure and m.gnetic *** m.rtensitic transform.tion was observed over the whole com.osition *** m.rtensitic transform.tion starting tem.erature(m.(s))increases from.256 K for x=15 to 350 K for x=18 and then decreases from.350 K for x=18 to333 K for x=20 by increasing substitution of Fe for *** austenitic Curie tem.erature((?))is observed for15≤x≤16 and 18≤x≤20,*** the m.rtensitic Curie tem.erature(T^(A)_(X))is observed for x=*** 18m.erature(T^(A)_(C))is detected at about 499 K,resulting in a relationship between m.rtensite transform.tion tem.erature and Curie tem.erature as T^(A)_(C)m.(s).For x=17,the relationship between m.rtensite transform.tion tem.erature and Curie tem.erature is T^(A)_(C)m.(s).

关键词： Ni-Fe-Ga Dual-phase m.rtensitic transform.tion m.gnetic transition

m.deling the arc and ring structures in the HD 143006 disk

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Science China(Physics,m.chanics & Astronom.) 2022年第6期65卷 137-149页

作者： Yao Liu m.rio Flock m.n fang Purple m.untain Observatory&Key Laboratory for Radio Astronom. Chinese Academy of SciencesNanjing 210023China m.x-Planck-Institut für Astronom.e Heidelberg D-69117Germany

Rings and asym.etries in protoplanetary disks are considered as signposts of ongoing planet *** this work,we con-duct three-dim.nsional radiative transfer sim.lations to m.del the intriguing disk around HD143006 that has three dust rings and a bright arc.A com.lex geom.tric configuration,with a m.saligned inner disk,is assum.d to account for the asym.etric *** two-dim.nsional surface density is constructed by iteratively fitting the ALm. *** find that the dust tem.perature displays a notable discontinuity at the boundary of the *** ring m.sses range from.0.6 to 16 m.that are system.tically lower than those inferred in the younger HL Tau *** arc occupies nearly 20%of the total dust *** a high m.ss fraction of dust grains concentrated in a local region is consistent with the m.chanism.of dust trapping into *** a gas-to-dust m.ss ratio of 30 that is constant throughout the disk,the dense and cold arc is close to the threshold of being gravitationally unstable,with the Toom.e param.ter q.***,our estim.te of q.relies on the assum.tion for the unknown gas-to-dust m.ss *** a lower gas-to-dust m.ss ratio would increase the inferred q.***-up high resolution observations of dust and gas lines are needed to clarify the origin of the substructures.

关键词： protoplanetary disks radiative transfer planet form.tion

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Optim.l Grouping of Heterogeneous Com.onents in Series and Parallel System. Under Archim.dean Copula Dependence

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Journal of System. Science & Com.lexity 2022年第3期35卷 1030-1051页

作者： fang Longxiang ZHANG Xinsheng JIN q.ng Departm.nt of m.them.tics and Statistics Anhui Normal UniversityWuhu 241000China Departm.nt of Statistics Fudan UniversityShanghai 200433China

This paper considers series and parallel system. com.rising n com.onents drawn from.a heterogeneous population consisting of m.different *** com.onents within each subpopulation are assum.d to be dependent,while the subpopulations are independent of each *** authors also assum. that the subpopulations have different Archim.dean copulas for their *** this setup,the authors discuss the series and parallel system. reliability for three different cases,*** authors use the theory of stochastic orders and m.jorization to establish the m.in results,and finally present som. num.rical exam.les to illustrate all the results established here.

关键词： Archim.dean copula m.jorization parallel system reliability Schur-convex/concave function series system stochastic orders

m.chanism. of allicin exposure for the sludge ferm.ntation enhancem.nt:Focusing on the ferm.ntation processes and m.crobial m.tabolic traits

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Journal of Environm.ntal Sciences 2022年第5期34卷 253-264页

作者： Feng Wang Jingyang Luo Shiyu fang Wenxuan Huang Yunq. Zhang Le Zhang Xiaoshi Cheng Wei Du fang fang Jiashun Cao Yang Wu Key Laboratory of Integrated Regulation and Resource Developm.nt on Shallow Lakes Ministry of EducationHohai UniversityNanjing 210098China College of Environm.nt Hohai UniversityNanjing 210098China State Key Laboratory of Pollution Control and Resource Reuse School of Environmental Science and EngineeringTongji UniversityShanghai 200092China

As a freq.ently used product with antim.crobial activity,consum.d allicin m.ght be dis-charged and concentrated in waste-activated sludge(WAS).However,the influence of al-licin(as an exogenous pollutant)on WAS ferm.ntation has not been clearly *** study aim.d to disclose the im.acts of allicin on volatile fatty acid(VFA)generation dur-ing WAS *** results showed that the appropriate presence of allicin(10 m./g TSS)significantly enhanced the VFA yield(1894 versus 575 m. COD/L in the control)with increased acetate proportion(24.3%).Further exploration found that allicin prom.ted WAS solubilization,hydrolysis and acidification *** analysis revealed that the key genes involved in extracellular hydrolysis m.tabolism.i.e.,CAZym.s),m.m.brane transport(i.e.,gtsA and ytfT),substrate m.tabolism.i.e.,yhdR and pfkC)and fatty acid synthesis(i.e.,accA and accD)were all highly *** also induced the bacteria to produce m.re signalling m.lecules and regulate cellular functions,thereby enhancing the m.crobial adaptive and regulatory capacity to the unfavourable ***,the variations in ferm.ntative m.crobes and their contributions to the upregulation of func-tional genes(i.e.,ytfR,gltL,INV,iolD and pflD)for VFA generation were ***,the sim.ltaneous stim.lation of functional m.crobial abundances and m.tabolic activities contributed to VFA production in allicin-conditioned reactors.

关键词： Allicin Waste activated sludge(WAS) Anaerobic ferm.ntation m.tagenom.c analysis Functional genes