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Earthquake Research in China 2020年第3期34卷 452-464页

作者： HOU Jinxin xie fan REN Yaqiong WANG Baoshan Key Laboratory of Seismic Observation and Geophysical Imaging Institute of GeophysicsChina Earthquake AdministrationBeijing 100081China School of Earth and Space Sciences University of Science and Technology of ChinaHefei 230026China

With the more complete acoustic emission(AE)catalog improved by the multi-channel AE matched-filter technique(MFT),we study the spatiotemporal evolution of the AE activities after laboratory stick-slip events incorporate with the slip data recorded by displacement transducers on an^1.5 m granite *** results show that the number of the AE events identified by MFT is about 9 times larger than that of the traditional method.A logarithmic expansion of early AE events along the fault strike is observed as a function of time,whereas the fault does not slip in the same ***,we related the expansion of the early AE events along the fault to the stress transfer caused by the adjacent AE ***,there is a good correlation between the cumulative number of the later AE events and the amount of fault *** suggests that the stress change caused by the continuous slip of the simulated fault after the stick-slip events response for the later AE events near or on the simulated fault.

关键词： Stick-slip Acoustic emission matched-filter technique Spatiotemporal evolution Fault slip

猪卵泡液外泌体处理卵巢颗粒细胞的SNP/Indel筛选分析

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畜牧兽医学报 2024年第2期55卷 576-586页

作者：刘阳光章会斌文浩宇谢帆赵世明丁月云郑先瑞殷宗俊张晓东安徽农业大学动物科技学院合肥230036

旨在分析卵泡液外泌体对卵巢颗粒细胞基因的影响,了解卵泡液外泌体在卵泡发育过程中的调控机理,为母猪繁殖研究提供理论依据。本研究选取6月龄、健康状态良好且体重相近的二元母猪为材料,屠宰后收集卵巢150枚,利用梯度离心法获取卵泡液... 详细信息

旨在分析卵泡液外泌体对卵巢颗粒细胞基因的影响,了解卵泡液外泌体在卵泡发育过程中的调控机理,为母猪繁殖研究提供理论依据。本研究选取6月龄、健康状态良好且体重相近的二元母猪为材料,屠宰后收集卵巢150枚,利用梯度离心法获取卵泡液外泌体与猪卵巢颗粒细胞(porcine ovarian granulosa cells,POGCs),并在体外将卵泡液外泌体与猪卵巢颗粒细胞共培养。通过RNA-seq技术对猪卵巢颗粒细胞(granulosa cell samples,GC,n=3)和与外泌体共培养的猪卵巢颗粒细胞(granulosa-exosome co-culture samples,GCE,n=3)进行测序。结果显示,在GC和GCE组中平均每个样品获得5.54×10^(7)条clean reads,Q20和Q30质量得分均在92%以上。在GC和GCE组的6个样品中共获得1310979个SNPs突变和104498个InDel突变,其中纯合型SNP/Indel突变数量为170426个,杂合型SNP/Indel突变数量为1245052个,突变杂合子数目明显高于纯合子且SNP的发生率较高。另外,在突变类型中,转换类型共计973003个,颠换类型339974个,转换的类型显著高于颠换类型。经基因注释,突变主要发生在基因3′UTR、5′UTR、内含子区域,其次为外显子和基因间隔区。另外,通过与差异基因对比后,够筛选出1583个候选基因,经GO和KEGG功能富集发现,候选基因主要与细胞周期以及细胞增殖/凋亡过程相关。此外,共发现14个与细胞周期、增殖/凋亡通路相关的关键候选基因,其中11个基因存在互作关系。本研究获得的这些SNP/Indel信息可为后续研究外泌体在母猪生殖上的调控奠定科学基础。

关键词：猪卵泡液外泌体卵巢颗粒细胞 SNP RNA-seq

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Modified cellular automaton model for modeling of microstructure and microsegregation in solidification of ternary alloys

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中国有色金属学会会刊：英文版 2006年第A02期16卷 180-185页

作者：朱鸣芳 CAO Wei-sheng CHEN Shuang-lin xie fan-you HONG Chun-pyo CHANG Y. Austin School of Materials Science and Engineering Southeast University Nanjing 210096 China Department of Materials Science and Engineering University of Wisconsin-Madison 1509 University Avenue Madison WI 53706 USA CompuTherm LLC 437 S. Yellowstone Dr. Suite 217 Madison WI 53719 USA Center for Computer-Aided Materials Processing （CAMP） Department of Metallurgical Engineering Yonsei University Shinchon-dong 134 Seodaemun-ku Seoul 120-749 Korea

A modified cellular automaton (MCA) model has been extended to the ternary alloy system by coupling thermodynamic and phase equilibrium calculation engine PanEngine. In the present model the dendrite growth is driven by the difference between the local equilibrium liquidus temperature and local actual temperature, incorporating the effect of curvature. The local equilibrium liquidus temperature is calculated with PanEngine according to the local liquid concentrations of two solutes, which are determined by numerically solving the species transport equation in the domain. Model validation was carried out through the comparison of the simulated values to the prediction of the Scheil model for solute profiles in the primary dendrites. The simulated data with zero solid diffusivity and limited liquid diffusivity were increasingly close to the Scheil profiles as the solidification rate decreased. The simulated microstructure and microsegregation in an Al-Cu-Mg ternary alloy were compared with those obtained experimentally.

关键词：三元合金体系凝固显微结构模型显微偏析细胞自动机

肝脏肿瘤微波消融术中氢吗啡酮与吗啡的镇痛效果比较

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中国当代医药 2024年第7期31卷 108-113页

作者：牛树国郑宁刚刘源颜克松谢凡柴文晓甘肃省武威市中医医院介入科甘肃武威733000 甘肃省人民医院肿瘤介入科甘肃兰州730000

目的比较氢吗啡酮与吗啡在肝脏肿瘤微波消融术(MWA)中的镇痛效果。方法选取2020年11月至2022年1月甘肃省人民医院收治的56例肝脏肿瘤患者作为研究对象,患者均行CT引导下MWA治疗,使用随机数字表法将患者分为试验组(28例)和对照组(28例),... 详细信息

目的比较氢吗啡酮与吗啡在肝脏肿瘤微波消融术(MWA)中的镇痛效果。方法选取2020年11月至2022年1月甘肃省人民医院收治的56例肝脏肿瘤患者作为研究对象,患者均行CT引导下MWA治疗,使用随机数字表法将患者分为试验组(28例)和对照组(28例),对照组脱落3例,最终纳入25例,试验组术中使用氢吗啡酮镇痛,对照组术中使用吗啡镇痛。比较两组患者术前(T_(0))、穿刺时(T_(1))、消融5 min时(T_(2))、消融10 min时(T_(3))术中最大视觉模拟评分法(VAS)评分时的生命体征及VAS评分等,评价两组药物的镇痛效果及安全性。结果两组患者的收缩压和舒张压组间、时间、交互作用比较,差异无统计学意义(P>0.05);试验组中T_(2)及T_(3)时的收缩压高于T_(0)及T_(1)时,差异有统计学意义(P0.05)。结论氢吗啡酮对局部麻醉下肝脏肿瘤MWA中的镇痛效果优于吗啡,二者不良反应发生率接近。术中疼痛会引起收缩压升高,但吗啡可减轻术中血压波动。

关键词：肝脏肿瘤微波消融术镇痛氢吗啡酮吗啡

Flotation separation of spodumene and albite with activation of calcium ion hydrolysate components

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Rare Metals 2022年第11期41卷 3919-3931页

作者： Xian-Ping Luo Yong-Bing Zhang He-Peng Zhou fan-Xin xie Zhi-Zhao Yang Bo-Yuan Zhang Cai-Gui Luo Engineering Research Center for High-Efficiency Development and Application Technology of Tungsten Resources(Jiangxi University of Science and Technology) Ministry of EducationGanzhou341000China Jiangxi Province Key Laboratory of Mining and Metallurgy Environmental Pollution Control Jiangxi University of Science and TechnologyGanzhou341000China

It is difficult to separate spodumene and albite by flotation with calcium ion as *** this study,microflotation experiment,solution chemistry calculation,density functional theory(DFT)calculation and X-ray photoelectron spectroscopy(XPS)analysis were conducted to investigate the effect mechanism of c alcium hydrolysate on the flotation separation of spodumene and *** show that the weak interaction intensity of Ca^(2+)with O atoms on the mineral surface makes it difficult to activate minerals *** O atom in the hydroxyl group of Ca(OH)^(+)and Ca(OH)_(2)can be strongly bonded with Al atom on the mineral surface,which greatly improves the adsorption *** the activation of Ca(OH)^(+),the adsorption forms of collectors on the surface of spodumene and albite are quite different,and the adsorption intensity on the surface of spodumene is higher,which is conducive to the flotation separation of spodumene and *** the action of Ca(OH)_(2),the adsorption of the collector on the albite surface is stronger than that of spodumene,which is not conducive to the flotation separation of the two *** adjusting the initial concentration of calcium ions and pulp pH,Ca(OH)^(+)is the main active component,which is the key to improve the separation effect of spodumene and albite.

关键词： Spodumene Albite Calcium ions Hydrolysate components Flotation Separation

“牛奶的科学”课程思政元素挖掘、设计与实践

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食品工业 2024年第4期45卷 242-245页

作者：谢凡夏永军王光强宋馨艾连中上海理工大学健康科学与工程学院上海200093

“牛奶的科学”涉及科学精神、工匠精神、工程伦理等多方面的知识要素,蕴藏着重要的人文价值要义。将食品安全、技术创新、人文精神等结合,多维度深入挖掘“牛奶的科学”课程思政元素,并对课程教学内容和思政元素进行针对性设计,以专业... 详细信息

“牛奶的科学”涉及科学精神、工匠精神、工程伦理等多方面的知识要素,蕴藏着重要的人文价值要义。将食品安全、技术创新、人文精神等结合,多维度深入挖掘“牛奶的科学”课程思政元素,并对课程教学内容和思政元素进行针对性设计,以专业思政的形式帮助学生树立正确的价值观和理想信念,实现思政元素与课程内容有机结合、教学相宜的教学效果,完成高校立德树人和提高人才培养质量的任务。课程实践取得的成果可为食品科学与工程专业其他文化通识课提供借鉴和参考。

关键词：牛奶的科学课程思政设计

NbB_(2)Modified Al-Cu Alloys Fabricated by Freeze-Ablation Casting under High Cooling Rate Solidification

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Acta Metallurgica Sinica(English Letters) 2024年第5期37卷 921-938页

作者： Xiang Kong Yu Wang Hong Xu Haotian fan Yuewu Zheng Beibei xie School of Materials Science and Engineering North University of ChinaTaiyuan 030051China

At present,improving the properties of aluminum alloys is generally achieved by increasing the cooling rate of the melt and adding micro-nano *** the cooling rate of the melt to improve the refining effect of grain refiner is still a difficult problem in the aluminum alloy casting *** innovative and environmentally friendly casting process,known as freeze ablation,was introduced during the preparation of an Al–NbB_(2) intermediate *** process significantly enhanced the cooling rate of the *** results indicated that the Al–NbB_(2) intermediate alloy produced under high cooling rates had a noticeable refining effect on Al–Cu alloys,with smaller NbB2 particles demonstrating superior refining *** average grain size of the refined Al–Cu alloy decreased from 154 to 69μm,the tensile strength increased by 12%,the fluidity increased by 18.4%,and the hot tearing index decreased from 144 to *** matching degree between NbB_(2) andα-Al was calculated using high-resolution transmission electron microscopy and the edge-to-edge *** was found that the atomic interplanar spacing and the interatomic spacing mismatch between NbB_(2)’splane and Al were both less than 10%,which further proved that NbB2 could serve as an effective nucleation site forα-Al grains to achieve grain refinement.

关键词： Grain refinement Freeze ablation Particle size control Mechanical properties Process properties

Temporal and environmental factors drive community structure and function of methanotrophs in volcanic forest soils

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Journal of Forestry Research 2024年第2期35卷 1-13页

作者： Rusong Chai Hongjie Cao Qingyang Huang Lihong xie fan Yang Hongbin Yin Heilongjiang Forest Botanical Garden Harbin 150040People’s Republic of China 2 Institute of Natural Resources and Ecology Science Academy of Heilongjiang ProvinceHarbin 150040People’s Republic of China

Methanotrophs,organisms that obtain oxygen by oxidizing methane,are recognized as the only known biological sink for atmospheric CH_4,and forest soil methanotrophs play crucial roles in mitigating global *** succession patterns of methanotrophic communities and functions in Wudalianchi volcano forest soils could provide a basis for the study of evolutionary mechanisms between soil microorganisms,the environment,and carbon cycling of temperate forest ecosystems under climate *** this study,the characteristics and drivers of methanotrophic community structure and function of two volcanic soils at different stages of development are analyzed,including an old volcano and a new volcano,which most recently erupted 300 years and 17-19×10^(5)years ago,respectively,and a non-volcano hills as control,based on space for time substitution and Miseq sequencing and bioinformation *** results showed that CH_(4) fluxes were significantly higher in old-stage volcano forest soils than new-stage forest soils and non-volcano forest *** were significant differences in the community composition and diversity of soil methanotrophs from different volcano forest *** was the dominant genus in all soil ***,the relative abundance of Methylococcus,along with Clonothrix,Methyloglobulus,Methylomagum,Methylomonas and Methylosarcina,were the important genera responsible for the differences in methanotrophic community structure in different volcano forest *** relative abundance of methanotroph belonging toγ-proteobacteria was significantly higher than that belonging toα-proteobacteria(P<0.05).Chao1,Shannon and Simpson indices of soil methanotrophic community were significantly lower in new-stage volcanos and were significantly affected by bulk density,total porosity,p H,nitrate,dissolved organic carbon and dissolved organic *** were significant differences in community structure between new-stage and old-stage volcano

关键词： Methanotrophs pmo A Soil development stage Volcanoes Forest soils

Mechanical and microstructural response of densified silica glass under uniaxial compression: Atomistic simulations

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Chinese Physics B 2020年第10期29卷 507-514页

作者： Yi-fan xie Feng Feng Ying-Jun Li Zhi-Qiang Hu Jian-Li Shao Yong Mei School of Science China University of Mining and TechnologyBeijing 100083China State Key Laboratory for Geomechanics and Deep Underground Engineering China University of Mining and TechnologyBeijing 100083China State Key Laboratory of Explosion Science and Technology Beijing Institute of TechnologyBeijing 100081China Institute of Defense Engineering AMSPLABeijing 100036China

We investigate the mechanical and microstructural changes of the densified silica glass under uniaxial loading-unloading via atomistic simulations with a modified BKS potential. The stress–strain relationship is found to include three respective stages: elastic, plastic and hardening regions. The bulk modulus increases with the initial densification and will undergo a rapid increase after complete densification. The yield pressure varies from 5 to 12 GPa for different densified samples. In addition, the Si–O–Si bond angle reduces during elastic deformation under compression, and 5-fold Si will increase linearly in the plastic deformation. In the hardening region, the peak splitting and the new peak are both found on the Si–Si and O–O pair radial distribution functions, where the 6-fold Si is increased. Instead, the lateral displacement of the atoms always varies linearly with strain, without evident periodic characteristic. As is expected, the samples are permanently densified after release from the plastic region, and the maximum density of recovered samples is about 2.64 g/cm^3, which contains 15 % 5-fold Si, and the Si–O–Si bond angle is less than the ordinary silica glass. All these findings are of great significance for understanding the deformation process of densified silica glass.

关键词： silica glass uniaxial compression densification atomistic simulation

Molecular Dynamics Simulations of Displacement Cascade in Ni-Based Concentrated Solid Solution Alloys

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Acta Mechanica Solida Sinica 2024年第1期37卷 82-89页

作者： Chaoquan Zhao Rongxuan xie Chuanlong Xu Xiaobao Tian Qingyuan Wang Wentao Jiang Haidong fan Department of Mechanics Sichuan UniversityChengdu 610065China

Single-phase concentrated solid solution alloys(SP-CSAs),including high-entropy alloys,have received extensive attention due to their excellent irradiation *** this work,displacement cascade simulations are conducted using the molecular dynamics method to study the evolution of defects in Ni-based *** with pure Ni,the NiCr,NiCo,and NiCu alloys exhibit a larger number of Frankel pairs(FPs)in the thermal peak stage,but a smaller number of surviving ***,the NiFe alloy displays the opposite *** explain these different observations for NiFe and other alloys,the formation energy and migration energy of interstitials/vacancies are *** the NiFe alloy,both the formation energy and migration energy barrier are *** the other hand,in NiCr and other alloys,the formation energy of interstitials/vacancies is lower,as is the migration energy barrier of *** energy analysis agrees well with previous *** present work provides new insights into the mechanism behind the irradiation resistance of binary Ni-based SP-CSAs.

关键词： Molecular dynamics simulation Displacement cascade Point defect Ni-based concentrated solid solution alloys