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BTG2 interference ameliorates high glucose-caused oxidative stress, cell apoptosis, and lipid deposition in HK-2 cells

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BIOCELL 2024年第9期48卷 1379-1388页

作者： WENJUAN ZHU ZHENGZHENG JU fan cui Department of Blood Transfusion The First People’s Hospital of WuhuWuhu241000China Department of Clinical Laboratory The First People’s Hospital of WuhuWuhu241000China

Objective:Diabetic nephropathy(DN)is a deleterious microangiopathy of diabetes,constituting a critical determinant of fatality in diabetic *** work is purposed to disclose the effects and modulatory mechanism of BTG anti-proliferation factor 2(BTG2)during the pathological process of ***:BTG2 expression in kidney tissues of diabetic mice and high glucose(HG)-exposed human proximal tubular cell line HK-2 was assessed with Western blot and *** diabetic mice model was constructed by streptozotocin injection and confirmed by the blood glucose level beyond 16.7 mmol/*** and eosin(H&E)staining and measurement of kidney function hallmarks were conducted to assess kidney *** counting kit(CCK)-8 method and TUNEL assay appraised cell activity and *** red O staining assayed lipid *** commercial kits were used to estimate oxidative stress-related ***-immunoprecipitation(Co-IP)assay testified the binding relationship of BTG2 with protein arginine methyltransferase 1(PRMT1).Results:BTG2 expression was significantly raised in renal tissues of diabetic mice and HK-2 cells exposed to ***2 deficiency improved viability and extenuated the apoptosis,lipid deposition as well as oxidative stress in HK-2 cells following HG *** addition,PRMT1 was also overexpressed in HK-2 cells exposed to ***2 interacted with PRMT1 and positively modulated PRMT1 *** effects of BTG2 interference on viability,apoptosis,lipid deposition,and oxidative stress in HG-challenged HK-2 cells were partially abrogated by PRMT1 ***:Altogether,BTG2 might aggravate HK-2 cell injury in response to HG by binding with PRMT1,providing a novel target for the therapeutic strategy of DN.

关键词： BTG2 Diabetic nephropathy Lipid deposition Oxidative stress PRMT1

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Study on Alfalfa Yield Improved by New Rare Earth Materials for Agriculture

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Journal of Rare Earths 2004年第Z1期22卷 269-270页

作者： fan Tianwen Abudukahar cui Yingguo Peng Jianzhang Wang Jiachen Grassland Working Station of Yili Yining 835000 China Grassland Working Station of Yili Yining 835000 China Grassland Working Station of Urumqi Urumqi 830000 China Grassland Working Station of Chapuchaer County Yili 835300 China Beijing General Research Institure for Nonferrous Metals Beijing 100088 China

New rare earth(RE) materials for agriculture including RE entire nutrition agent, amino acid chelated RE fertilizer, RE phosphate were used to alfalfa production in Grassland Working Station of Yili, Xinjiang Province, and repetition was 3 with 7 *** result shows that by using new RE materials, the average treatment height of alfalfa increases by 12.5% compared with traditional cultural, and the yield increases from 21.8% to 41.6% compared with that of traditional *** results show that the new materials have significant good effect on alfalfa production.

关键词： rare earth materials for agriculture alfalfa yield

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A Fair E-Cash Payment Scheme Based on Credit

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Wuhan University Journal of Natural Sciences 2006年第1期11卷 155-159页

作者： WANG Shao-bin HONG fan cui Guo-hua College of Computer Science and Technology Huazhong University of Science and TechnologyWuhan 430074 Hubei China

A new fair e-eash payment scheme based on credit is present in this paper. In the scheme, an overdraft credit certificate is issued to user by hank. Using the overdraft credit certificate, user can produce e-cash himself to pay in exchanges. Merchant can verify the e-cash received from user. Bank can make a fair dis pute resolution when there is a dissension between user and merchant. It can avoid ＇the problem of partition e-cash for changes, prevent from reusing e-cash and fa- king e-cash, It. fits justice, anonymity, non deny and impartiality.

关键词： overdraft credit off-line payment e-cash impartiality justice

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Classification of high-ordered topological nodes towards Moiré flat bands in twisted bilayers

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Science China(Physics,Mechanics & Astronomy) 2024年第9期67卷 133-147页

作者： fan cui Congcong Le Qiang Zhang Xianxin Wu Jiangping Hu Ching-Kai Chiu Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China School of Physical Sciences University of Chinese Academy of SciencesBeijing 100190China RIKEN Interdisciplinary Theoretical and Mathematical Sciences(iTHEMS) Wako 351-0198Japan CAS Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China Kavli Institute of Theoretical Sciences University of Chinese Academy of SciencesBeijing 100190China New Cornerstone Science Laboratory Beijing 100190China

At magic twisted angles,Dirac cones in twisted bilayer graphene(TBG)can evolve into flat bands,serving as a critical playground for the study of strongly correlated *** chiral symmetry is introduced,rigorous mathematical proof confirms that the flat bands are locked at zero energy in the entire Moiré Brillouin zone(BZ).Yet,TBG is not the sole platform that exhibits this absolute band *** to this flatness phenomenon are topological nodes and their specific locations in the *** this study,considering twisted bilayer systems that preserve chiral symmetry,we classify various ordered topological nodes in base layers and all possible node locations across different ***,we constrain the node locations to rotational centers,such as Γ and M points,to ensure the interlayer coupling retains equal strength in all *** this classification as a foundation,we systematically identify the conditions under which Moiré flat bands ***,through the extension of holomorphic functions,we provide proof that flat bands are locked at zero energy,shedding light on the origin of the band ***,beyond Dirac cones,numerous twisted bilayer nodal platforms can host flat bands with a degeneracy number of more than two,such as four-fold,six-fold,and *** multiplicity of degeneracy in flat bands might unveil more complex and enriched correlation physics.

关键词： twisted bilayer systems high-ordered topological nodes Moriéflat bands high degeneracy

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This issue overview

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Applied Geophysics 2018年第1期15卷 1-2页

作者： fan Wei-cui

Electrical and electromagnetic method Wang et *** an anomalous principal component decomposition method based on the Stratton-Chu *** airwaves and sea layers can be separated from the anomalous field,eliminating the airwave *** method is implemented in integral transform form,making it a robust processing method,is particularly effective for removing the effect of the entire sea layer.

关键词： This issue overview LWD

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Perioperative nursing principles guided by the concept of enhanced recovery after surgery

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Frontiers of Nursing 2021年第1期8卷 1-6页

作者： Hong-Jie Xie fan cui Wei-Bing Shuang Department of First Clinical Medical College Shanxi Medical UniversityTaiyuanShanxi 030001China Department of Urology The First Hospital of Shanxi Medical UniversityTaiyuanShanxi 030001China

Objective:To explore the clinical effect of perioperative nursing guided by the concept of enhanced recovery after surgery and summarize ***:Pubmed,Chinese National Knowledge Infrastructure(CNKI),Chinese Biomedical Literature Database(CBM),Wanfang Database,and VIP Database were searched to obtain the relevant literature involving enhanced recovery after surgery(ERAS)guidance,obtain the effective clinical data,review the reports in literature,and obtain the effective ***:Compared with the traditional nursing program,perioperative nursing principles guided by the concept of ERAS provide more accurate nursing care to patients and reduce the occurrence of intraoperative stress events through comprehensive nursing measures such as preoperative pre-rehabilitation measures,intraoperative body temperature and fluid management,postoperative analgesia,prevention of nausea and vomiting,early mobilization,catheter nursing,and better out-of-hospital ***:Perioperative nursing principles guided by the concept of ERAS can significantly reduce the incidence of perioperative complications,shorten the hospital stay of patients,and promote postoperative rehabilitation of *** transformation and implementation of this concept can bring significant benefits to hospitals,medical care,and patients.

关键词： enhanced recovery after surgery perioperative care prehabilitation measures intraoperative optimization measures postoperative rehabilitation measures

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Merkle Tree Digital Signature and Trusted Computing Platform

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Wuhan University Journal of Natural Sciences 2006年第6期11卷 1467-1472页

作者： WANG Xiaofei HONG fan TANG Xueming cui Guohua College of Computer Science and Technology Huazhong University of Science and Technology Wuhan 430074 Hubei China

Lack of efficiency in the initial key generation process is a serious shortcoming of Merkle tree signature scheme with a large number of possible signatures. Based on two kinds of Merkle trees, a new tree type signature scheme is constructed, and it is provably existentially unforgeable under adaptive chosen message attack. By decentralizing the initial key generation process of the original scheme within the signature process, a large Merkle tree with 6.87×10^10 possible signatures can be initialized in 590 milliseconds. Storing some small Merkle trees in hard disk and memory can speed up Merkle tree signature scheme. Mekle tree signature schemes are fit for trusted computing platform in most scenarios.

关键词： digital signature one-time signature Merkle tree trusted computing platform

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Tribenuron-Methyl Resistant Shepherd's Purse (Capsella bursa-pastoris (L.) Medik.) in Hebei Province of China

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Agricultural Sciences in China 2011年第8期10卷 1241-1245页

作者： WANG Gui-qi cui Hai-lan ZHANG Hong-jun ZHANG Yan-qiu LIU Xue LI Xiang-ju fan cui-qin Institute of Food and Oil Hebei Academy of Agriculture and Forestry SciencesShijiazhuang 000P.R.China State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant Protection （IPP）Chinese Academy of Agricultural Sciences （CAAS）Beijing 100193P.R.China Institute for the Control of Agrochemicals Ministry of AgricultureBeijing 100125P.R.China

Shepherd＇s purse seeds were collected from winter wheat fields and road sides in Hebei Province,*** sensitivities to tribenuron-methyl were evaluated in a whole plant dose response assay in the *** revealed that HB-1,HB-2,HB-3,HB-4,HB-6,HB-7,HB-17,HB-18,HB-19,HB-20,HB-21,and HB-22 populations were susceptible to tribenuron-methyl characterised by very low GR50 values of about 0.10 g *** the other hand,populations HB-15 and HB-16 had moderate resistance to tribenuron-methyl with resistance indices （RI） ranging from 10-100 folds,whilst populations HB-5,HB-8,HB-9,HB-10,HB-11,HB-12,HB-13,and HB-14 expressed high level of resistance to tribenuron-methyl with resistance indices over *** proportion of moderate resistance level was about 9.09%,and that of high resistance was about 36.36%.

关键词： ALS inhibitor tribenuron-methyl resistance shepherd's purse (Capsella bursa-pastoris (L.) Medik.)

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Bilateral occurrence of sperm granulomas in the left spermatic cord and on the right epididymis:A case report

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World Journal of Clinical Cases 2022年第29期10卷 10787-10793页

作者： Ding-Yang Lv Hong-Jie Xie fan cui Hui-Yu Zhou Wei-Bing Shuang Department of Urology The First Hospital of Shanxi Medical UniversityTaiyuan 030001Shanxi ProvinceChina

BACKGROUND Sperm granuloma is a rare disease in clinical andrology and its incidence is still unclear *** to the existing literature,sperm granuloma often occurs *** and ultrasound features are similar to epididymal tuberculosis,chronic epididymitis and other *** granuloma is usually diagnosed based on postoperative histopathological and immunohistochemical *** SUMMARY A 46-year-old man was admitted to the hospital due to the presence of a left scrotal mass for 3 mo and aggravation of pain for 1 *** lesions at both sites were surgically *** pathological examination showed that the left spermatic cord mass and the right epididymal mass were consistent with sperm *** sperm granulomas then recurred 3 mo after *** is little change in the local mass so *** The case report is helpful for our understanding of this *** clinical diagnosis,it should be distinguished from epididymal tuberculosis,chronic epididymitis and other *** Doppler ultrasound can be used as a preferred examination method but postoperative pathological examination is still needed for diagnosis.

关键词： Sperm granuloma Epididymis Spermatic cord Recurrence Case report

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Comparative study of functional optical zone:small incision lenticule extraction versus femtosecond laser assisted excimer laser keratomileusis

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International Journal of Ophthalmology(English edition) 2023年第2期16卷 238-244页

作者： Yao-Wen Song Meng-fan cui Yi Feng Min Qu Yan Gao Rui He Department of Excimer Laser Shanxi Eye HospitalTaiyuan 030002Shanxi ProvinceChina The First Clinical Medical College Shanxi Medical UniversityTaiyuan 030001Shanxi ProvinceChina

AIM:To investigate the size of functional optical zone(FOZ)after small incision lenticule extraction(SMILE)versus femtosecond laser assisted excimer laser keratomileusis(FS-LASIK)for myopia correction and potential associated factors for ***:A total of 133 patients who received corneal refractive surgery in our hospital between November 2018 and July 2021 were retrospectively *** were 63 patients(123 eyes)in SMILE group and 70patients(139 eyes)in FS-LASIK *** size of FOZ was measured using Pentacam 3-dementional anterior segment analyzer before and 3mo after surgery,so as to analyze postoperative achieved functional optical zone(AFOZ)and its contributing ***:When planned functional optical zone(PFOZ)was 6.5 mm for both groups,AFOZ was 1.45±0.27 and 1.67±0.25 mm smaller than preoperative FOZ in SMILE group and FS-LASIK group 3mo after *** in SMILE group was significantly larger than that in FS-LASIK group(P<0.001).Variation of FOZ was negatively correlated with preoperative spherical equivalent(SE)and positively correlated with variation of mean keratometry value(△Km),variation of spherical aberration(△SA),and variation of Q-value(△Q,all P<0.001)in both *** variable linear regression equations were△FOZ=1.354-0.1×pre-SE+0.336×△Q+1.462×△SA in SMILE group and△FOZ=1.512+0.137×△Q+0.468×△SA in FS-LASIK ***:AFOZ is significantly smaller than preoperative FOZ in both SMILE and FS-LASIK *** the same PFOZ,larger AFOZ is achieved in SMILE group than in FS-LASIK group.

关键词： functional optical zone small incision lenticule extraction femtosecondlaser assisted excimer laser keratomileusis spherical equivalent spherical aberration

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