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Does sevoflurane sedation in pediatric patients lead to“pseudo”leptomeningeal enhancement in the brain on 3 Tesla magnetic resonance imaging?

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World Journal of Radiology 2023年第4期15卷 127-135页

作者： Kiran Hilal Kumail khandwala Saima Rashid faheemullah khan Shayan Sirat Maheen Anwar Department of Radiology Aga Khan University HospitalKarachi 74800Pakistan Department of Anesthesiology Aga Khan University HospitalKarachi 74800Pakistan

BACKGROUND Prominent leptomeningeal contrast enhancement(LMCE)in the brain is observed in some pediatric patients during sedation for ***,based on clinical history and cerebrospinal fluid analysis,the patients are not acutely ill and do not exhibit meningeal *** study determined whether sevoflurane inhalation in pediatric patients led to this pattern of‘pseudo’LMCE(pLMCE)on 3 Tesla magnetic resonance imaging(MRI).AIM To highlight the significance of pLMCE in pediatric patients undergoing enhanced brain MRI under sedation to avoid misinterpretation in *** A retrospective cross-sectional evaluation of pediatric patients between 0-8 years of age was *** patients underwent enhanced brain MRI under inhaled *** LMCE grade was determined by two radiologists,and interobserver variability of the grade was calculated using Cohen’s *** LMCE grade was correlated with duration of sedation,age and weight using the Spearman rho rank *** A total of 63 patients were ***(22.2%)cases showed mild LMCE,48(76.1%)cases showed moderate LMCE,and 1 case(1.6%)showed severe *** found substantial agreement between the two radiologists in detection of pLMCE on post-contrast T1 imaging(kappa value=0.61;P<0.001).Additionally,we found statistically significant inverse and moderate correlations between patient weight and *** was no correlation between duration of sedation and *** pLMCE is relatively common on post-contrast spin echo T1-weighted MRI of pediatric patients sedated by sevoflurane due to their fragile and immature *** should not be misinterpreted for meningeal *** pertinent clinical history of the child is an essential prerequisite to avoid radiological overcalling and the subsequent burden of additional investigations.

关键词： Brain Pediatrics Gadolinium contrast Pseudo leptomeningeal enhancement 3 Tesla magnetic resonance imaging Sevoflurane

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Interobserver reliability between pediatric radiologists and residents in ultrasound evaluation of intraventricular hemorrhage in premature infants

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World Journal of Radiology 2022年第11期14卷 367-374页

作者： Muhammad Danish Barakzai Ayimen Khalid Zara Za Sheer faheemullah khan Naila Nadeem Noman khan Kiran Hilal Department of Radiology The Hospital for Sick ChildrenToronto 555Canada Department of Radiology Aga Khan University HospitalKarachi 74800Pakistan Community Health Sciences Aga Khan University HospitalKarachi 74800Pakistan

BACKGROUND Germinal matrix intraventricular hemorrhage(IVH)may contribute to significant morbidity and mortality in premature *** identification and grading of IVH affect decision-making and clinical *** is possibility of misinterpretation of the ultrasound appearances,and the interobserver variability has not been investigated between radiology resident and board-certified *** To assess interobserver reliability between senior radiology residents performing bedside cranial ultrasound during on-call hours and pediatric *** From June 2018 to June 2020,neonatal cranial ultrasound examinations were performed in neonatal intensive care *** findings were recorded by the residents performing the ultrasound and the pediatric attending *** In total,200 neonates were included in the study,with a mean gestational age of 30.9 *** agreement for higher grade(Grade III&IV)IVH was *** was substantial agreement for lower grade(Grade I&II)*** There is strong agreement between radiology residents and pediatric radiologists,which is higher for high grade IVHs.

关键词： Ultrasound head Neonatal cranial ultrasound Cranial ultrasound Intraventricular hemorrhage Neonatal intraventricular hemorrhage

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巴基斯坦北部某大型公路滑坡的形成机理（英文）

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土木与环境工程学报(中英文) 2023年

作者： AAMIR Asghar 苏立君赵波 ABRAR Niaz faheemullah 中国-巴基斯坦地球科学联合研究中心 4. Poonch Rawalakot大学 Azad Jammuand Kashmir Muzaffarabad大学中国科学院山地灾害与地表过程重点实验室中国科学院水利部成都山地灾害与环境研究所中国科学院大学

公路滑坡是山区公路安全运行的重要威胁，开展滑坡灾害评估尤为重要，尤其是深切峡谷区域的公路滑坡。以巴斯基坦北部Muzaffarabad-Mansehra公路沿线某大型滑坡为研究对象，采用野外调查、遥感分析、地貌解译、地球物理探勘和运动学分... 详细信息

公路滑坡是山区公路安全运行的重要威胁，开展滑坡灾害评估尤为重要，尤其是深切峡谷区域的公路滑坡。以巴斯基坦北部Muzaffarabad-Mansehra公路沿线某大型滑坡为研究对象，采用野外调查、遥感分析、地貌解译、地球物理探勘和运动学分析等多种调查手段，进行滑坡的失稳特征、触发机理、地下结构特征和边坡稳定评估等研究，结果表明：滑坡发生在Hazara地层中，该地层以顺层斜坡为主，容易发生翘曲变形等破坏，属于滑坡易发地层。地球物理探勘表明：滑坡体内部存在多个不同深度和厚度的复杂结构组成，低电阻率区（0.325～1350Ωm）以松散、饱水的堆积体为主，高电阻率区域（1510～26092Ωm）与覆盖层有关，包括冲积层、巨石和干板岩碎片等。地震反射层析结果表明，在高度饱和的覆盖层、改造区块和表层风化层内，P波速度较低（400～1800 m/s）；而下垫层散布着高密度岩石碎片和大块巨石，P波速度在3000～5000 m/s。两种地球物理探勘结果均表明滑坡体内有一条延伸30m深的破碎带，这是触发滑坡的重要因素。滑坡顶部的滑动面在深度25～30m处，在主体处的滑动面深度在45m处。运动学分析表明：锲形体失稳是公路滑坡的主要破坏模式。研究结果表明，采用综合技术分析滑坡灾害的潜在机制可以有效减轻此类灾害带来的相关风险。

关键词： Lohar Gali滑坡片状岩石地貌学地球物理成像巴基斯坦北部

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