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damage mechanism identification in composites via machine learning and acoustic emission

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npj Computational Materials 2021年第1期7卷 852-866页

作者： C.Muir B.Swaminathan A.S.almansour K.Sevener C.Smith M.Presby J.d.Kiser T.M.Pollock S.daly Materials department University of California-Santa BarbaraSanta BarbaraCAUSA NASA Glenn Research Center ClevelandOHUSA Materials Scienceand Engineering department University of Michigan-Ann ArborAnn ArborMIUSA Mechanical Engineering department University of California-Santa BarbaraSanta BarbaraCAUSA

damage mechanism identification has scientific and practical ramifications for the structural health monitoring,design,and application of composite *** advances in machine learning uncover pathways to identify the waveform-damage mechanism relationship in higher-dimensional spaces for a comprehensive understanding of damage *** review evaluates the state of the field,beginning with a physics-based understanding of acoustic emission waveform feature extraction,followed by a detailed overview of waveform clustering,labeling,and error analysis *** requirements for damage mechanism identification in any machine learning framework,including those currently in use,under development,and yet to be explored,are discussed.

关键词： composites composite mechanism

Bacterial microbiome of Coptotermes curvignathus （Isoptera： Rhinotermitidae） reflects the coevolution of species and dietary pattern

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Insect Science 2014年第5期21卷 584-596页

作者： Jie Hung Patricia King Nor Muhammad Mahadi Choon fah Joseph Bong Kian Huat Ong Osman Hassan Faculty of Agriculture and Food Sciences Universiti Putra Malaysia Bintulu Sarawak Campus Sarawak Malaysia Genome Institute Jalan Bangi Lama 43000 Kajang Faculty of Science and Technology UniversiU Kebangsaan Malaysia 43600 UKM BangiSelangor Malaysia

Coptotermes curvignathus Holmgren is capable of feeding on living trees. This ability is attributed to their effective digestive system that is furnished by the termite＇s own cellulolytic enzymes and cooperative enzymes produced by their gut microbes. In this study, the identity of an array of diverse microbes residing in the gut of C. curvignathus was revealed by sequencing the near-full-length 16S rRNA genes. A total of 154 bacterial phylotypes were found. The Bacteroidetes was the most abundant phylum and accounted for about 65% of the gut microbial profile. This is followed by Firmicutes, Actinobacteria, Spirochetes, Proteobacteria, TM7, deferribacteres, Planctomycetes, Ferrucomicrobia, and Termite Group 1. Based on the phylogenetic study, this symbiosis can be a result of long coevolution of gut enterotypes with the phylogenic distribution, strong selection pressure in the gut, and other speculative pressures that determine bacterial biome to follow. The phylogenetic distribution of cloned rRNA genes in the bacterial domain that was considerably different from other termite reflects the strong selection pressures in the gut where a proportional composition of gut microbiome of C. curvignathus has established. The selection pressures could be linked to the unique diet preference of C. curvignathus that profoundly feeds on living trees. The delicate gut microbiome composition may provide available nutrients to the host as well as potential protection against opportunistic pathogen.

关键词： Coptotermes curvignathus diet preference gut microbiome selection

A machine learning framework for damage mechanism identification from acoustic emissions in unidirectional SiC/SiC composites

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npj Computational Materials 2021年第1期7卷 1326-1335页

作者： C.Muir B.Swaminathan K.Fields A.S.almansour K.Sevener C.Smith M.Presby J.d.Kiser T.M.Pollock S.daly Materials University of California-Santa BarbaraSanta BarbaraCAUSA Mechanical Engineering University of California-Santa BarbaraSanta BarbaraCAUSA NASA Glenn Research Center ClevelandOHUSA Materials Science and Engineering University of Michigan-Ann ArborAnn ArborMIUSA

In this work,we demonstrate that damage mechanism identification from acoustic emission(AE)signals generated in minicomposites with elastically similar constituents is *** waveforms were generated by SiC/SiC ceramic matrix minicomposites(CMCs)loaded under uniaxial tension and recorded by four sensors(two models with each model placed at two ends).Signals were encoded with a modified partial power scheme and subsequently partitioned through spectral *** cracking and fiber failure were identified based on the frequency information contained in the AE event they produced,despite the similar constituent elastic properties of the matrix and ***,the resultant identification of AE events closely followed CMC damage chronology,wherein early matrix cracking is later followed by fiber breaks,even though the approach is fully domain-knowledge ***,the partitions were highly precise across both the model and location of the sensors,and the partitioning was *** presented approach is promising for CMCs and other composite systems with elastically similar constituents.

关键词： composites damage mechanism

A secondary bile acid from microbiota metabolism attenuates ileitis and bile acid reduction in subclinical necrotic enteritis in chickens

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Journal of Animal Science and Biotechnology 2020年第3期11卷 767-776页

作者： Mohit Bansal Ying Fu Bilal Alrubaye Mussie Abraha Ayidh almansour Anamika Gupta Rohana Liyanage Hong Wang Billy Hargis Xiaolun Sun Center of Excellence for Poultry Science University of Arkansas1260 W Maple St.O409FayettevilleAR 72701USA CEMB University of ArkansasFayettevilleAR 72701USA department of Chemistry University of ArkansasFayettevilleAR 72701USA.

Background:Clostridium perfringens-induced chicken necrotic enteritis(NE)is responsible for substantial economic losses worldwide ***,as a result of antibiotic growth promoter prohibition,the prevalence of NE in chickens has *** study was aimed to reduce NE through titrating dietary deoxycholic acid(dCA)as an effective antimicrobial *** and methods:day-old broiler chicks were assigned to six groups and fed diets supplemented with 0(basal diet),0.8,1.0 and 1.5 g/kg(on top of basal diet)*** birds were challenged with Eimeria maxima(20,000 oocysts/bird)at d 18 and ***(109 CFU/bird per day)at d 23,24,and 25 to induce *** birds were sacrificed at d 26 when ileal tissue and digesta were collected for analyzing histopathology,mRNA accumulation and *** colonization by real-time PCR,targeted metabolomics of bile acids,fluorescence in situ hybridization(FISH),or terminal deoxynucleotidyl transferase dUTP nick end labeling(TUNEL)***:At the cellular level,birds infected with *** and *** developed subclinical NE and showed shortening villi,crypt hyperplasia and immune cell infiltration in *** dCA alleviated the NE-induced ileal inflammation in a dose-dependent manner compared to NE control *** with the increased histopathological scores,subclinical NE birds suffered body weight gain reduction compared to the uninfected birds,an effect attenuated with increased doses of dietary *** the molecular level,the highest dose of dCA at 1.5 g/kg reduced *** luminal colonization compared to NE birds using PCR and ***,the dietary dCA reduced subclinical NE-induced intestinal inflammatory gene expression and cell apoptosis using PCR and TUNEL *** further examining ileal bile acid pool through targeted metabolomics,subclinical NE reduced the total bile acid level in ileal digesta compared to uninfected ***,dietary dCA increased total

关键词： Bile acid Chicken Clostridium perfringens deoxycholic acid Intestinal inflammation Necrotic enteritis

Phytochemical composition,biological propensities,and in-silico studies of Crateva adansonii dC.:A natural source of bioactive compounds

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Food Bioscience 2022年第5期49卷 1124-1132页

作者： Irfan Pervaiz Muhammad Hasnat Saeed Ahmad Umair Khurshid Hammad Saleem Farhan Alshammari Khaled almansour Adriano Mollica Kannan R.R.Rengasamy Syafiq Asnawi Zainal Abidin Sirajudheen Anwar department of Pharmacy The University of ChenabGujratPakistan Institute of Pharmaceutical Sciences(IPS) University of Veterinary&Animal Sciences(UVAS)LahorePakistan department of Pharmaceutical Chemistry Faculty of PharmacyThe Islamia University of BahawalpurPakistan department of Pharmaceutics College of PharmacyUniversity of HailHailSaudi Arabia department of Pharmacy University‘G.D’Annunzio of Chieti-Pescara66100ChietiItaly Centre for Transdisciplinary Research Department of PharmacologySaveetha Dental CollegeSaveetha Institute of Medical and Technical Sciences(SIMATS)Chennai600077India Jeffrey Cheah School of Medicine and Health Sciences Monash UniversityJalan Lagoon Selatan47500Bandar SunwaySelangor Darul EhsanMalaysia department of Pharmacology and Toxicology College of PharmacyUniversity of HailHailSaudi Arabia

The current research work aimed at the phytochemical,biological,and in-silico properties of hydro-methanol extract and n-hexane fraction of Crateva adansonii aerial *** bioactive content and UHPLC-MS analysis were used to determine the phytochemical *** biological activities,antioxidant(dPPH,ABTS,FRAP,CUPRAC,phosphomolybdenum,and metal chelation)and enzyme inhibition(againstα-amylase,tyrosinase,acetylcholinesterase-AChE,and butyrylcholinesterase-BChE)activities were *** hydro-methanol extract contained higher phenolic(28.09 mg GAE/g extract)and flavonoid(65.61 mg RE/g extract)contents,which might be correlated with the higher antioxidant potential of this *** the enzyme assays,the n-hexane fraction was most active against BChE andα-amylase,while the methanol extract presented higher inhibition values against AChE and tyrosinase ***,different phytocompounds have been tentatively identified by UHPLC-MS of hydro-methanol extract;most of these belonged to phenolic and flavonoid ***,three important identified phytocompounds(isovitexin,robinetin 3-rutinoside,and luteolin 7-robinobioside),were selected for in-silico computational studies against the tyrosinase *** present investigation revealed that the studied extract/fraction of *** are likely sources of phytoconstituents identified through UHPLC-MS with considerable antioxidant and enzyme inhibitory *** conclude,the evaluated plant should be further investigated for the isolation of bioactive molecules which can be utilized in phytopharmaceuticals.

关键词： Crateva adansonii phytochemicals Antioxidant Enzyme inhibition docking

砂拉越中华文化传承与多元文化融合之探讨 ——以古晋亚答街的“古晋文化缤纷庆中秋庆典”为例

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砂拉越中华文化传承与多元文化融合之探讨 ——以古晋亚答街的“...

作者：刘淑花（LIU SOK fah）西北大学

学位级别：硕士

中秋节是华人社会中重要的节庆。华人迁移至世界各地也带着自己的中华文化,并融合当地环境文化,形成更多姿多彩缤纷的“中秋节”。砂拉越华人入乡随俗,与多元民族和谐相处,共荣共存。彼此共同庆祝彼此的文化佳节,因此各自的文化也会加... 详细信息

中秋节是华人社会中重要的节庆。华人迁移至世界各地也带着自己的中华文化,并融合当地环境文化,形成更多姿多彩缤纷的“中秋节”。砂拉越华人入乡随俗,与多元民族和谐相处,共荣共存。彼此共同庆祝彼此的文化佳节,因此各自的文化也会加入其他民族的文化特点,以加强彼此之间的联系与尊重。古晋亚答街的“古晋缤纷文化庆中秋庆典”就是最佳的例子。本文的研究对象是砂拉越中华文化传承与多元文化融合之探讨,以古晋亚答街的“古晋文化缤纷庆中秋庆典”为例,文章主要包括以下五部分:绪论首先确定选题意义,在对中华文化与砂拉越多元民族之间文化特征的基础上与现况,提出本文的研究思路,即围绕砂拉越亚答街的“古晋缤纷文化庆中秋庆典”,并以庆典的角度探讨其背后对中华文化传承与多元文化融合的内涵。第一章首先是对砂拉越的多元文化环境进行概念界定,然后追溯华族先贤迁移至砂拉越的生活与发展。第二章主要是针对中华节庆的,结合中华文化的发展历程与中秋节的意义进行探讨。第三章探讨古晋亚答街的中华文化精神,并从中进行“古晋缤纷文化庆中秋庆典”多元文化融合的分析。总论古晋亚答街的“古晋缤纷文化庆中秋庆典”活动对中华文化传承与多元文化融合的影响。总之,中秋节的“团圆”含义,也意味着“和谐”。在文化传承的过程中也蕴含着多元化“和谐融合”的时代寓意,中华文化融合多元文化值得探讨研究。

关键词：中华文化中秋节砂拉越

基于属性偏序《卢氏实用伤寒论讲义》之学术思想探讨

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基于属性偏序《卢氏实用伤寒论讲义》之学术思想探讨

作者：黄显华（Wong Han fah）广州中医药大学

学位级别：硕士

目的:岭南医学作为中医药的一个分支,已有一千年多的历史。邓铁涛教授认为,中国作为中医药学术中心,有一个逐渐从黄河流域转移到长江流域再转移到珠江流域的趋势。邓铁涛教授首先探讨了岭南医学领域的研究,并指导了岭南医学史研究组织... 详细信息

目的:岭南医学作为中医药的一个分支,已有一千年多的历史。邓铁涛教授认为,中国作为中医药学术中心,有一个逐渐从黄河流域转移到长江流域再转移到珠江流域的趋势。邓铁涛教授首先探讨了岭南医学领域的研究,并指导了岭南医学史研究组织进行了岭南医学史的研究。《伤寒论》的研究一直是中医理论研究的热门课题之一,现代科技已经有对《伤寒论》方证系统性的进行全面、客观和多层次的知识发现,这对于《伤寒论》的传承具有重大的意义。方剂-症状、方剂-舌脉、方剂-中药系统的《伤寒论》研究是中医方证对应研究的重要组成部分,对于中医理论客观化,规范化和中医临床疗效的提升都具有很大的帮助。由此可见,无论从中医经典传承或是对方证对应的角度而言,针对《伤寒论》其方剂-症状、方剂-舌脉、方剂-中药系统的现代研究都是巨有很大的研究价值。燕山大学洪文学教授将现代严密的形式概念分析理论数学方法和中医数量化辨证诊断结合,提出了一种基于可变尺度属性偏序结构图的多层次复杂概念网络生成方法,描述了事物的普遍性和特殊性。在中医诊断证名自动生成和中医诊断知识发现领域做出了卓有成效的研究成果。因此,为了解决中医复杂概念网络研究中出现的问题,本文以经典文献研究岭南伤寒论医家卢觉愚的《卢氏实用伤寒论讲义》学术著作。将基于属性偏序结构图的多层次复杂概念网络生成方法,对《卢氏实用伤寒论讲义》中的方剂-症状、方剂-舌脉、方剂-中药之间的关系及相关的知识结构进行研究,并试探其中可能隐含的知识为中医经典著作的传承及临床应用提供一种新的研究方法。通过构建《卢氏实用伤寒论讲义》方证结构群多层次复杂概念网络进行知识发现:第一,发现《卢氏实用伤寒论讲义》每一方对应的“症候群”及其内涵之基本发病机制,治疗原则,治疗方法和功效的结构知识,并进行各类方的比较与鉴别。第二,发现《卢氏实用伤寒论讲义》各种典型的证候,症状和体征等对应的常用方剂和选方鉴别,並进行各类方证用方用药的探析。方法:本文研究《卢氏实用伤寒论讲义》以广州中医药大学图书馆藏馆的影印版本为蓝本。根据广州中医药大学伤寒教研室《伤寒论》多年专业的教学、科研及临床经验,利用原文字词为表现形式,将《卢氏实用伤寒论讲义》中的全因素、规范化提取其方剂、症状、舌脉、中药组成等内容并构建“方剂-症状”、“方剂-舌脉”、“方剂-中药”数据知识库。通过相关数据制成Excel表格,应用数学原理,借助基于属性偏序结构图的多层次复杂概念网络生成方法,将Excel表格生成属性偏序结构示意图。对《卢氏实用伤寒论讲义》这部著作结构性进行知识分析与鉴定。对方剂、症状、舌脉、中药群结构与簇集子群结构基本规律,在不同状态和阶段以偏序结构图展现概念之间的复杂网络关系,从而进行数据化挖掘和可视化的表达进行解释和发现。此外以综述方式研究《觉庐医案新解》并举例了5则病案,探析卢氏在经方临床应用的学术思想,以期对卢氏研究《伤寒论》学术思想上进行补充。结果:根据建立的《卢氏实用伤寒论讲义》“方剂-症状”、“方剂-中药”、“方剂-舌脉”知识数据库,以113首方剂为对象,121项症状、21项舌脉、85种中药为属性,生成“方剂-症状”、“方剂-舌脉”、“方剂-中药”属性偏序结构图总图。所生成的属性偏序结构图,进行《卢氏实用伤寒论讲义》学术思想探析和知识发现。本文初步使用形式概念属性偏序结构图原理的多层次复杂概念网络生成方法,成功有效的描述多层次中医复杂概念和概念层次,对中医文献研究具有工具性和方法性的指导意义,为大数据知识发现提供了新的思路和方法。

关键词：伤寒论岭南医学方证形式概念分析属性偏序结构图

Evaluation of Toxicological Risk Related to Presence of Lead and Cadmium in <i>Moringa oleifera</i>Lam. Leaves Powders Marketed in Cotonou (Benin)

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Food and Nutrition Sciences 2014年第9期5卷 770-778页

作者： Alain K. Aissi Elisabeth Yehouenou Pazou Théodora A. Ahoyo Lauris fah Brice Fanou Luc Koumolou Hornel Koudokpon Clément Agbangla Kissao Gnandi Frédéric Loko Patrick A. Edorh Laboratory of Genetics Faculty of Science and Technology University of Abomey-Calavi Cotonou Benin Laboratory of Management Treatment and Valuation of Waste (GTVD) Faculty of Sciences University of Lome Lome Togo Laboratory of Management Treatment and Valuation of Waste (GTVD) Faculty of Sciences University of Lome Lome Togo department of Biochemistry and Cellular Biology Faculty of Science and Technology University of Abomey-Calavi Cotonou Benin Laboratory of Toxicology and Environmental Health Interfaculty Center of Formation and Research in Environment for the Sustainable Development University of Abomey-Calavi Cotonou Benin Research Laboratory in Applied Biology Polytechnic School of Abomey-Calavi University of Abomey-Calavi Cotonou Benin Research Laboratory in Applied Biology Polytechnic School of Abomey-Calavi University of Abomey-Calavi Cotonou Benin Laboratory of Toxicology and Environmental Health Interfaculty Center of Formation and Research in Environment for the Sustainable Development University of Abomey-Calavi Cotonou Benin

To evaluate lead and cadmium contamination in Moringa oleifera leaves powders marketed in Cotonou and health risks associated with its consumption, cross-sectional and analytical study were done from October 23th, 2012 to June 20th, 2013. Samples of Moringa powders were purchased at different outlets (health centers, supermarkets, pharmacy, etc.). Assays were performed by atomic absorption spectrophotometry after digestion according calcination method. Pb and Cd levels were compared with Codex Alimentarius standards, using the Student t test. daily Exposure doses (ddE) and Hazard Quotients (HQ) specific to each contaminant were calculated using a conventional method. Results revealed that the mean concentration of lead for all samples (1.526 mg/kg) exceeded of about 5.08 times the maximum allowable limit whereas cadmium levels (0.246 mg/kg) was not statistically higher than the standard. The highest concentrations of Pb and Cd are respectively 4.263 mg/kg and 0.354 mg/kg. Children are 2.3 to 3.8 times in greater danger than adults although all Qd calculated are less than 1, reflecting that there is a low risk to consumers in general. For both metals, dJE specifically linked to the consumption of Moringa was less than 2% compared to other kinds of food intake. In conclusion, the current level of contamination (with lead and cadmium) of Moringa leaves powders marketed in Cotonou is not yet an alarming threat to consumers’ health. However, care must be taken to reduce chemical pollution especially soils where these plants grow.

关键词： Moringa oleifera Lead Cadmium Hazard Food Supplement

Epitypification:should we epitypify?

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2008年第10期9卷 842-846页

作者： Kevin d. HYdE Ying ZHANG International Fungal Research and development Centre the Research Institute of Resource Insects Chinese Academy of Forestry Kunming 650224 China Fungal Research Group School of Science Mae Fah Luang University Tasud Muang Chiang Rai 5 7100 Thailand Centre for Research in Fungal diversity School of Biological Sciences University of Hong Kong Hong Kong China

Epitypification can solve many taxonomic problems and stabilize the understanding of species, genera, families or orders. The aim of this paper is to illustrate how to epitypify. A few examples where taxa have been epitypified are considered and the benefits and disadvantages of epitypification are discussed. We also outline some examples of taxa which need to be epitypifled with reasons.

关键词： Colletotrichum GenBank Molecular phylogeny Taxonomy Typification