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Circulation of Brucellaceae,Anaplasma and Ehrlichia *** borderline of Iran,Azerbaijan,and Armenia

Asian Pacific Journal of Tropical Medicine 2021年第5期14卷 223-230页

作者： Rahimeh Abdoli Hasan Bakhshi Sedigheh Kheirandish faezeh faghihi Asadollah Hosseini-Chegeni Mohammad Ali Oshaghi Zakkyeh Telmadarraiy Mohammad Mehdi Sedaghat Department of Medical Entomology and Vector Control School of Public HealthTehran University of Medical SciencesTehranIran Department of Oral and Maxillofacial Pathology School of DentistryBushehr University of Medical SciencesBushehrIran Cellular and Molecular Research Center Iran University of Medical SciencesTehranIran Department of Plant Protection Faculty of AgricultureLorestan UniversityKhorramabadIran Rahyan Novin Danesh(RND)Private University SariMazandaranIran

Objective:To estimate the infection of ticks to Anaplasma,Ehrlichia,Babesia,Theileria,and Brucellaceae using molecular methods in borderline of Iran,Azerbaijan,and ***:Totally,2022 ticks were collected from different ***,species were diagnosed under stereomicroscope according to valid morphological *** DNA was extracted followed by PCR to detect Anaplasma,Ehrlichia,Theileria,Babesia and Brucellaceae infection in ***:A total of 498 males[24.62%(95%CI 22.76%-26.57%)],741 females[36.64%(95%CI 34.54%-38.79%)],782 nymphs[38.67%(95%CI 36.55%-40.84%)]and 1 larva[0.04%(95%CI 0.00%-0.28%)]were *** identified samples,we found four genera including Hyalomma,Rhipicephalus,Haemaphysalis,and *** assay revealed that the prevalence of ticks to Anaplasma or Ehrlichia,and Brucellaceae was 22.02%(95%CI 16.01%-29.06%)and 15.03%(95%CI 9.43%-22.26%),*** analysis showed that the identified Anaplasma *** the most similarity with Anaplasma centrale,Anaplasma platys,Anaplasma camelii,and Anaplasma phagocytophilum,submitted in ***,the detected Ehrlichia *** Brucellaceae bacterium had the most similarity with Ehrlichia ruminantium and Mycoplana peli,***,no sign of the presence of Theileria and Babesia *** seen in the studied ***:Anaplasmosis,ehrlichiosis and brucellosis should be considered as important health threats in northwestern Iran and consistent monitoring on infection of ticks and livestock should be performed regularly.

关键词： Tick Anaplasma Ehrlichia Brucellaceae PCR

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Distribution of Tick Species Infesting Domestic Ruminants in Borderline of Iran-Afghanistan

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Journal of Biomedical Science and Engineering 2014年第12期7卷 982-987页

作者： Ahmad Jafarbekloo Hassan Vatandoost Alireza Davari faezeh faghihi Hasan Bakhshi Maryam Roya Ramzgouyan Mohammad Nasrabadi Zakkyeh Telmadarraiy School of Medicine Tehran University of Medical Sciences (TUMS) Tehran Iran School of Public Health Tehran University of Medical Sciences (TUMS) Tehran Iran Depatment of Tissu Engineering Iran University of Medical Sciences (IUMS) Tehran Iran School of Advanced Technologies in Medicine Tehran University of Medical Sciences (TUMS) Tehran Iran

To determine the tick species parasitizing domestic ruminants in Zabol, Zahak and Qaen Counties which are located in east of Iran and are bordered with Afghanistan country, about 73 sheep, 44 goats and 27 cattle of 12 herds in several villages in Zabol, Zahak and Qaen Counties were inspected for tick infestation. Separated ticks were preserved in 70% alcohol and identified. About 464 ticks (252 male;194 female) were collected;the occurrences of ticks on goats, cattle and sheep were about 17%, 15% and 26% respectively in all three Counties. The mean number of ticks on each animal was about 2 - 7 ticks per animal. Totally we found 3 genera hard ticks including Hyalomma, Rhipicephalus and Dermacentor in these regions. Hyalomma anatolicum, Hy. marginatum, Hy. asiaticum, Hy. detrinium, Rhipicephalus bursa, R. sanguineus, Dermacentorniveus, and D. marginatus, were the tick species we found. Hyalomma anatolicum and Hy. asiaticum were the most abundant species in the study area. The result of this study is a survey of tick species from domestic animals in east part of Iran and implication of possible prevention measures for diseases transmitted by ticks.

关键词： Tick Ruminants Borderline Iran Afghanistan

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Molecular Detection of <i>Anaplasma</i>and <i>Ehrlichia</i>Infection in Ticks in Borderline of Iran-Afghanistan

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Journal of Biomedical Science and Engineering 2014年第11期7卷 919-926页

作者： Ahmad Jafarbekloo Hasan Bakhshi faezeh faghihi Zakkyeh Telmadarraiy Atefeh Khazeni Mohammad Ali Oshaghi Maryam Roya Ramzgouyan Mohammad Mehdi Sedaghat School of Medicine Tehran University of Medical Sciences (TUMS) Tehran Iran School of Public Health Tehran University of Medical Sciences (TUMS) Tehran Iran Cellular and Molecular Research Center Iran University of Medical Sciences Tehran Iran School of Advanced Technologies in Medicine Tehran University of Medical Sciences Tehran Iran

Anaplasmosis, a disease caused by various species of Anaplasma, poses important economic constraints to animal breeders. Ehrlichiosis is a worldwide zoonosis illness and mostly occurs in tropical and subtropical regions that are close to the vector’s distribution. Tick-borne pathogens lead to over 100,000 cases of illness in the world each year. Besides the costs of the additional veterinary care, anaplasmosis causes abortion in animals, reduction of milk production, body weight, and frequently leads to death. In this study, we investigated on infection of ticks to Anaplasma and Ehrlichia pathogens in Zabol and Zahak County in Sistan and Baluchestan Province where is bordered with Afghanistan. Totally from June 2013 to May 2014, 369 ticks were caught from goats, cows and sheep. Molecular studies on 53 of these samples which represented all specimens, showed that Ehrlichia’s DNA and Anaplasma’s DNA was found in 14 (26.4%) out of the 53 selected specimens. The results showed the infection of Rhipicephalus sanguineus and Hyalomma anatolicum with Anaplasma ovis. Also we saw infection of H. anatolicum and H. asiaticum ticks to Ehrlichia spp. This study has been intended to do a comprehensive survey of Ehrlichia and Anaplasma distribution in ticks caught from east of Iran;it was designed to investigate the presence of Anaplasma spp. and Ehrlichia spp. in Zabol and Zahak Counties, Iran. These results show that these pathogens should be controlled in such regions.

关键词： Anaplasma Ehrlichia Tick Iran

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POLYMERIZATION OF N,N'-(PYROMELLITOYL)-BIS-L-LEUCINE DIACID CHLORIDE WITH HYDANTOIN DERIVATIVES BY MICROWAVE IRRADIATION

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Chinese Journal of Polymer Science 2004年第4期22卷 343-348页

作者： Khalil faghihi Organic Polymer Chemistry Research Laboratory Department of Chemistry Faculty of Science Arak University Arak 38156 Iran

Facile and rapid polycondensation reactions of N,N'-(pyromellitoyl)-bis-L-leucine diacid chloride 1 with eight different derivatives of hydantoin compounds 2a-h were developed by using a domestic microwave oven in the presence of a small amount of polar organic medium such as o-cresol. The polycondensation reactions proceeded rapidly, compared with the conventional solution polycondensation, and was completed within 7-10 min, producing a series of novel optically active poly(amide-imide)s 3a-h with high yield and inherent viscosity of 0.35-0.65 dL/g. All of the above polymers were fully characterized by FT-IR, elemental analyses, inherent viscosity (η inh ), solubility test and specific rotation. Some structural characterization and physical properties of these optically active poly(amide-imide)s are reported.

关键词： Microwave-assisted rapid polycondensation Optically active polymers Poly(amide-imide)s Hydantoin derivatives N,N'-(Pyromellitoyl)-bis-L-leucine diacid chloride

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SYNTHESIS AND CHARACTERIZATION OF OPTICALLY ACTIVE POLY(AMIDE-IMIDE)S CONTAINING PHOTOSENSITIVE CHALCONE UNITS IN THE MAIN CHAIN

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Chinese Journal of Polymer Science 2010年第5期28卷 695-704页

作者： Khalil faghihi Hassan Moghanian Organic Polymer Chemistry Research Laboratory Department of ChemistryFaculty of ScienceArak UniversityArak 38156Iran

A series of new optically active poly（amide-imide）s were synthesized by direct polycondensation reaction of 4,4＇-diaminochalcone with several N-trimellitylimido-L-amino acids using a tosyl chloride （TsCl）, pyridine （Py） and dimethylformamide （DMF） system as condensing agent. The resulting thermally stable poly（amide-imide）s were obtained in good to high yields and inherent viscosities ranging between 0.35 dL/g and 0.58 dL/g and were characterized with FTIR, IH-NMR, CHN, Ultraviolet, TGA and DTG techniques.

关键词： Poly(amide-imide)s Chalcone moeity Polycondensation Optically active polymers.

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Core designing of a new type of TVS-2M FAs:neutronics and thermal-hydraulics design basis limits

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Frontiers in Energy 2021年第1期15卷 256-278页

作者： Saeed GHAEMI Farshad faghihi Department of Nuclear Engineering School of Mechanical EngineeringShiraz UniversityShiraz 71936-16548Iran Radiation Research Center Shiraz UniversityShiraz 71936Iran Lonizing and Non-Ionizing Radiation Center Shiraz University of Medical ScienceShirazIran

One of the most important aims of this study is to improve the core of the current VVER reactors to achieve more burn-up(or more cycle length)and more intrinsic *** is an independent study on the Russian new proposed FAs,called TVS-2M,which would be applied for the future advanced *** important aspects of neutronics as well as thermal hydraulics investigations(and analysis)of the new type of Fas are conducted,and results are compared with the standards PWR *** TVS-2M FA contains gadolinium-oxide which is mixed with UO_(2)(for different Gd densities and U-235 enrichments which are given herein),but the core does not contain *** new type TVS-2M Fas are modeled by the SARCS software package to find the PMAXS format for three states of CZP and HZP as well as HFP,and then the whole core is simulated by the PARCS code to investigate transient *** addition,the WIMS-D5 code is suggested for steady core modeling including TVS-2M FAs and/or TVS *** neutronics aspects such as the first cycle length(first cycle burn up in terms of MWthd/kgU),the critical concentration of boric acid at the BOC as well as the cycle length,the axial,and radial power peaking factors,differential and integral worthy of the most reactive CPS-CRs,reactivity coefficients of the fuel,moderator,boric acid,and the under-moderation estimation of the core are conducted and benchmarked with the PWR ***,the burn-up calculations indicate that the 45.6 d increase of the first cycle length(which corresponds to 1.18 MWthd/kgU increase of burnup)is the best improving aim of the new FA type called ***,thermal-hydraulics core design criteria such as MDNBR(based on W3 correlation)and the maximum of fuel and clad temperatures(radially and axially),are investigated,and discussed based on the CDBL.

关键词： TVS-2M FAs core design basis limits VVER-1000 analysis mixture of uranium-gadolinium oxides fuels thermal-hydraulics PARCS WIMS-D5

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New optically active poly(amide-imide)s derived from N,N'-(4,4-diphthaloyl)-bis-L-leucine and hydantoin derivatives:Synthesis and properties

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Chinese Chemical Letters 2009年第10期20卷 1153-1156页

作者： Khalil faghihi Polymer Chemistry Research Laboratory Department of ChemistryFaculty of ScienceIslamic Azad UniversityArak BranchArakIran

Six new optically active poly（amide-imide）s （5a-f） were synthesized through the direct polycondensation reaction of N,N′-（4,4′- diphthaloyl）-bis-L-leucine （3） with six hydantoin derivatives （4a-f）. Tripbenyl phosphite （TPP）/pyridine in the presence of calcium chloride （CaCl2） and N-methyl-2-pyrrolidone （NMP） were successfully applied for direct polycondensation. The polycondensation reactions produce a series of new poly（amide-imide）s （5a-f） in high yields, and inherent viscosity between 0.42 and 0,55 dL/g. The resulting poly（amide-imide）s （5a-f） were characterized by elemental analysis, viscosity measurements, thermal gravimetric analysis （TGA and DTG）, solubility test and FT-IR spectroscopy.

关键词： High performance polymers Poly(amide-imide)s Direct polycondensation Hydantoin derivatives

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Synthesis and characterization of new polyesters based on 2,5-bis[(4-chloro carboxyanilino)carbonyl]pyridine and aromatic diols

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Chinese Chemical Letters 2010年第1期21卷 13-17页

作者： Khalil faghihi Polymer Research Laboratory Department of ChemistryFaculty of ScienceIslamic Azad UniversityBranch ArakArakIran

Six new polyesters 7a-f were synthesized through the solution polycondensation reaction of diacid chloride 5 with six aromatic diols 6a-f in N,N-dimethyl acetamide(DMAc) as solvent in the presence of pyridine as *** polycondensation reaction produced a series of novel polyester containing pyridyl moiety in the main chain in high yields with inherent viscosities between 0.35 and 0.54 dL/*** resulted polymers were fully characterized by means of FT-IR spectroscopy,elemental analyses,inherent viscosity ...

关键词： High-performance polymers Polyesters Pyridyl moiety Aromatic diols

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RAPID SYNTHESIS OF NOVEL OPTICALLY ACTIVE POLY(AMIDE-IMIDE)S DERIVED FROM N,N'-(PYROMELLITOYL)-BIS-L-ALANINE DIACID CHLORIDE AND HYDANTOIN DERIVATIVES UNDER MICROWAVE IRRADIATION

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Chinese Journal of Polymer Science 2005年第1期23卷 63-69页

作者： Khalil faghihi Azizollah Mirsamie Organic Polymer Chemistry Research Laboratory Department of ChemistryFaculty of ScienceArak UniversityArak38156Iran Chemical Engineering DeptFaculty of EngineeringAzad Univertsity of ArakArakIran Organic Polymer Chemistry Research LaboratoryDepartment of ChemistryFaculty of ScienceArak UniversityArak38156Iran

Eight novel poly(amide-imide)s were synthesized under microwave irradiation by using a domestic microwaveoven from the polycondensation reactions of N.N'-(pyromellitoyl)-bis-L-alanine diacid chloride(1)with eight differentderivatives of hydantoin compounds(2a-h)in the presence of a small amount of a polar organic medium such as *** polycondensation proceeded rapidly,compared with the conventional solution polycondensation and was completedwithin 8-10 min,producing a series of new poly(amide-imide)s(3a-h)with inherent viscosities about 0.35-0.68 dL/g inhigh *** obtained PAIs(3a-h)were fully characterized by means of FT-IR spectroscopy,elemental analyses,inherentviscosity(ηinh),solubility and specific rotation *** of the resulting polymers show optical rotation and areoptically *** properties of the poly(amide-imide)s were investigated by using thermal gravimetric analysis(TGA).

关键词： Microwave-assisted polycondensation Optically active polymers 5,5-Disubstituted hydantoin derivatives.

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OPTICALLY ACTIVE AND FLAME-RETARDANT POLY(AMIDE-IMIDE)S BASED ON PHOSPHINE OXIDE MOIETY AND N,N′-(PYROMELLITOYL)BIS-L-AMINO ACID IN THE MAIN CHAIN:SYNTHESIS AND CHARACTERIZATION

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Chinese Journal of Polymer Science 2010年第4期28卷 517-525页

作者： Khalil faghihi Mohsen Hajibeygi Organic Polymer Chemistry Research Laboratory Department of ChemistryFaculty of ScienceArak UniversityArak 38156Iran

Six new optically active and flame-retardant poly（amide-imide）s PAls 5a-5f containing phosphine oxide moiety as a flame-retardant unit in the main chain were synthesized from direct polycondensation reaction of six chiral N,N＇-（pyromellitoyl）-bis-L-amino acid 3a-3f with bis（3-aminophenyl）phenyl phosphine oxide 4 in a medium consisting of N-methyl-2-pyrrolidone （NMP）, triphenyl phosphite （TPP）, calcium chloride （CaCl2） and pyridine. The polymerization reactions produced a series of optically active poly（amide-imide）s with good yield and good inherent viscosity of 0.34-0.70 dLg^-1. The resulted polymers were fully characterized by means of FTIR and ^1H-NMR spectroscopy, gel permeation chromatography （GPC）, elemental analyses, inherent viscosity and solubility tests. Thermal properties and flameretardant behavior of the PAIs 5a-5f were investigated using thermal gravimetric analysis （TGA and DTG） and limiting oxygen index （LOI）. Data obtained by thermal analysis （TGA and DTG） revealed that these polymers showed good thermal stability. Furthermore, high char yield in TGA and good LOI values indicated that the resulting polymers were capable of exhibiting good flame retardant properties. N,N＇-（pyromellitoyl）-bis-L-amino acids 3a-3f were prepared in quantitative yields by the condensation reaction of pyromellitic dianhydride （1,2,4,5-benzenetetracarboxylicacid-1,2,4,5-dianhydride） 1 with L-alanine 2a, L-valine 2b, L-leucine 2c, L-isoleucine 2d, L-phenyl alanine 2e and L-2-aminobutyric acid 2f in acetic acid solution.

关键词： Optically active Flame-retardant polymers Poly(amide-imide)s Limiting oxygen index

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