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Report of Haemophilus Influenzae serotype a intracranial infections in older children

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Pediatric Investigation 2023年第2期7卷 132-136页

作者： Varvara Probst fadi Shahoud Aaron Fletcher Osborne Ana Alvarez Nizar Maraqa Ayesha mirza Department of Pediatrics University of Florida College of Medicine-JacksonvilleJacksonvilleFloridaUSA Department of Pediatrics Division of Infectious Diseases and ImmunologyUniversity of Florida College of Medicine-JacksonvilleJacksonvilleFloridaUSA

Introduction:Haemophilus influenzae(Hi)is subdivided into typeable(a-f)and non-typeable *** serotype b(Hib)has historically been one of the important pathogens responsible for invasive ***,after widespread Hib vaccination,the emergence of other Hi serotypes,specifically Hi serotype a(Hia),was noted during the last few decades,mostly in children younger than 5 years of *** presentation:We present two cases of severe intracranial infections with detected Hia in patients>5 years of age within a short time frame and within the same geographic ***:Epidemiological studies and surveillance on Hia-related illnesses in all age groups worldwide are needed to better understand the clinical and epidemiological characteristics of *** can establish a platform to develop a candidate vaccine against Hia that might protect children of all ages.

关键词： Haemophilus influenzae serotype b intracranial infection vaccine epidemiology

Minimum-Time and Minimum-Jerk Gait Planning in Joint Space for Assistive Lower Limb Exoskeleton

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Journal of Bionic Engineering 2023年第5期20卷 2164-2178页

作者： Habib Mohamad Sadjaad Ozgoli fadi Motawej Department of Electrical and Computer Engineering Tarbiat Modares UniversityTehran14117-13116Iran Department of Mechatronics Engineering Tishreen UniversityLattakia0096341Syria

Assistive lower limb exoskeleton robot has been developed to help paraplegic patients walk again.A gait planning method of this robot must be able to plan a gait based on gait parameters,which can be changed during the stride according to human intention or walking *** gait is usually planned in cartesian space,which has shortcomings such as singularities that may occur in inverse kinematics equations,and the angular velocity of the joints cannot be entered into the ***,it is vital to have a gait planning method in the joint *** this paper,a minimum-time and minimum-jerk planner is proposed for the robot *** do so,a third-order system is defined,and the cost function is introduced to minimize the jerk of the joints throughout the *** minimum time required is calculated to keep the angular velocity trajectory within the range specified by the motor’s maximum *** conditions of the joints are determined to secure backward balance and fulfill gait ***,the proposed gait planning method is tested by its implementation on the Exoped®exoskeleton.

关键词： Bionic robot Gait planning Optimization Complete paraplegic Lower limb exoskeleton

聚醚有机硅PSPE助剂对25%噻虫嗪水分散粒剂在豇豆花瓣表面润湿性能影响

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农药 2024年第6期63卷 401-407页

作者：叶火春闫超朱发娣张静许致远冯岗中国热带农业科学院环境与植物保护研究所海口571101 农业农村部热带作物有害生物综合治理重点实验室海口571101

[目的]了解豇豆花瓣表面润湿性能,提高防治药剂精准施药水平。[方法]采用座滴法测定豇豆花的旗瓣内外侧、翼瓣内外侧和龙骨瓣外侧等5个花瓣表面的接触角,采用朱定一(ZDY)法计算其固体表面自由能,进一步测定了25%噻虫嗪水分散粒剂(WG)稀... 详细信息

[目的]了解豇豆花瓣表面润湿性能,提高防治药剂精准施药水平。[方法]采用座滴法测定豇豆花的旗瓣内外侧、翼瓣内外侧和龙骨瓣外侧等5个花瓣表面的接触角,采用朱定一(ZDY)法计算其固体表面自由能,进一步测定了25%噻虫嗪水分散粒剂(WG)稀释液及其添加PSPE助剂后药液在花瓣表面的静态和动态接触角,并采用最大泡压法测定噻虫嗪药液及其添加助剂后药液动态表面张力(DST)。[结果]豇豆5个花瓣表面除了旗瓣外侧表面为亲水型,其他4个花瓣表面均为疏水型(接触角θ大于90°),花瓣表面自由能值在23.15~60.31 mJ/m^(2)之间。25%噻虫嗪WG的250、125 mg/L处理药液在豇豆花瓣表面上总体润湿性差,添加PSPE助剂后,药液对豇豆花瓣表面接触角在30 s时降至20°以下,静态接触角降低75%以上,显著低于未添加助剂的药液。添加助剂的药液在5个豇豆花瓣表面的接触角下降趋势相似,在0~10 s内快速下降而后平稳降低,DST在50~500 ms内快速降低,在10 s时降至23.15 mN/m及以下。药液添加助剂浓度由0.05%提高至0.1%,DST下降更快,5 s后在旗瓣内侧、翼瓣内外侧和龙骨瓣外侧表面接触角均低于10°,药液DST快速下降区时间提前。[结论]添加聚醚有机硅PSPE助剂可使25%噻虫嗪WG喷雾药液在豇豆花瓣表面快速润湿铺展。

关键词：豇豆花接触角表面自由能动态表面张力喷雾助剂噻虫嗪水分散粒剂

IoMT-Cloud Task Scheduling Using AI

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Computer Modeling in Engineering & Sciences 2023年第5期135卷 1345-1369页

作者： Adedoyin A.Hussain fadi Al-Turjman Computer Engineering Department and Research Centre for AI and IoT Near East UniversityNicosiaTurkey Computer Engineering Department CyprusWest UniversityGazimagusaTurkey Artificial Intelligence Engineering Department and AI and Robotics Institutes Near East UniversityNicosiaTurkey Research Centre for AI and IoT Faculty of EngineeringUniversity of KyreniaKyreniaTurkey

The internet of medical things(IoMT)empowers patients to get adaptable,and virtualized gear over the *** scheduling is the most fundamental problem in the IoMT-cloud since cloud execution commonly relies on ***,a proposition is being made for a distinct scheduling technique to suitably meet these *** manage the scheduling issue,an artificial intelligence(AI)method known as a hybrid genetic algorithm(HGA)is *** proposed AI method will be justified by contrasting it with other traditional optimization and AI scheduling *** CloudSim is utilized to quantify its effect on various parameters like time,resource utilization,cost,and *** proposed AI technique enhanced the viability of task scheduling with a better execution rate of 32.47ms and a reduced time of ***,the experimented outcomes show that the HGA reduces cost as well as time profoundly.

关键词： Artificial intelligence IoMT hybrid genetic algorithm cloud

Chimeric Antigen Receptors and Regulatory T Cells:The Potential for HLA-Specific Immunosuppression in Transplantation

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Engineering 2022年第3期8卷 30-43页

作者： Sabrina Wright Conor Hennessy Joanna Hester fadi Issa Nuffield Department of Surgical Sciences University of OxfordOxford OX39DUUK

Chimeric antigen receptors(CARs)are a breakthrough in genetic engineering that have revolutio nized the field of adoptive cellular therapy(ACT).Cells expressing these receptors are rerouted to a predefined target by the inclusion of an antigen-specific binding region within the synthetic CAR *** advantage of cells with programmed specificity has been demonstrated clinically in the field of oncology,and it is clear that such cells have greater accuracy,potency,and reduced off-target therapeutic effects compared with their unmodified *** contrast to conventional T cells(Tconvs),regulatory T cells(Tregs)play a major role in suppressing immune activation and regulating the host immune *** expression within Tregs has been proposed as a therapy for autoimmune and inflammatory diseases,graft-versus-host disease(GVHD),and organ transplant rejectio *** the latter,they hold immense potential as mediators of immune tolerance for recipients of ***,current research into CAR-Treg engineering is extremely limited,and there is uncertainty regarding optimal design for therapeutic *** review examines the rationale behind the development of CAR-Tregs,their significance for human transplantation,potential designs,safety considerations,and comparisons of CAR-Tregs in transplantation models to date.

关键词： Chimeric antigen receptors T cell Treg Alloimmunity Bioengineering Transplant Autoimmunity

Outpatient insulin use in type 2 diabetes mellitus and acute respiratory distress syndrome outcomes:A retrospective cohort study

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World Journal of Clinical Cases 2024年第17期12卷 2966-2975页

作者： Georges Khattar Samer Asmar Laurence Aoun Fares Saliba Shaza Almardini Saif Abu Baker Catherine Hong Carolla El Chamieh fadi Haddadin Toni Habib Omar Mourad Zeina Morcos Fatema Arafa Jonathan Mina Khalil El Gharib Mohammad Aldalahmeh Salman Khan Elie Bou Sanayeh Department of Medicine Holy Spirit University of KaslikJounieh 00000Lebanon Department of Internal Medicine Staten Island University HospitalStaten IslandNY 10305United States Public Heath and Biostatistics Independent ResearchBeirut 0000Lebanon Department of Medicine Lebanese UniversityBeirut 00000Lebanon Department of Medicine University of BalamandBeirut 00000Lebanon Department of Medicine Lebanese American UniversityBeirut 00000Lebanon Department of Medicine Northwell Health Staten Island University HospitalNew YorkNY 10305United States

BACKGROUND The impact of type 2 diabetes mellitus(T2DM)on acute respiratory distress syndrome(ARDS)is debatable.T2DM was suspected to reduce the risk and complications of ***,during coronavirus disease 2019(COVID-19),T2DM predisposed patients to ARDS,especially those who were on insulin at *** evaluate the impact of outpatient insulin use in T2DM patients on non-COVID-19 ARDS *** We conducted a retrospective cohort analysis using the Nationwide Inpatient Sample *** patients diagnosed with ARDS were stratified into insulin-dependent diabetes mellitus(DM)(IDDM)and non-insulindependent DM(NIDDM)*** applying exclusion criteria and matching over 20 variables,we compared cohorts for mortality,duration of mechanical ventilation,incidence of acute kidney injury(AKI),length of stay(LOS),hospitalization costs,and other clinical *** Following 1:1 propensity score matching,the analysis included 274 patients in each ***,no statistically significant differences emerged between the IDDM and NIDDM groups in terms of mortality rates(32.8%vs 31.0%,P=0.520),median hospital LOS(10 d,P=0.537),requirement for mechanical ventilation,incidence rates of sepsis,pneumonia or AKI,median total hospitalization costs,or patient disposition upon *** Compared to alternative anti-diabetic medications,outpatient insulin treatment does not appear to exert an independent influence on in-hospital morbidity or mortality in diabetic patients with non-COVID-19 ARDS.

关键词： Acute respiratory distress syndrome Type 2 diabetes mellitus Insulin Length of stay Mortality Endotracheal intubation Acute kidney injury Coronavirus disease 2019

Wearable Sensor:An Emerging Data Collection Tool for Plant Phenotyping

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Plant Phenomics 2023年第3期5卷 399-417页

作者： Cheng Zhang Jingjing Kong Daosheng Wu Zhiyong Guan Baoqing Ding fadi Chen College of Engineering Nanjing Agricultural UniversityNanjing 210095China State Key Laboratory of Crop Genetics&Germplasm Enhancement and Utilization Key Laboratory of Biology of Ornamental Plants in East ChinaNational Forestry and Grassland AdministrationCollege of HorticultureNanjing Agricultural UniversityNanjing 210095China Zhongshan Biological Breeding Laboratory No.50 Zhongling StreetNanjing 210014China

The advancement of plant phenomics by using optical imaging-based phenotyping techniques has markedly improved breeding and crop ***,there remains a challenge in increasing the spatial resolution and accuracy due to their noncontact measurement *** sensors,an emerging data collection tool,present a promising solution to address these *** using a contact measurement mode,wearable sensors enable in-situ monitoring of plant phenotypes and their surrounding *** a few pioneering works have been reported in monitoring plant growth and microclimate,the utilization of wearable sensors in plant phenotyping has yet reach its full *** review aims to systematically examine the progress of wearable sensors in monitoring plant phenotypes and the environment from an interdisciplinary perspective,including materials science,signal communication,manufacturing technology,and plant ***,this review discusses the challenges and future directions of wearable sensors in the field of plant phenotyping.

关键词： Tool Wear enable

A comprehensive survey on security issues in vehicle-to-grid networks

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Journal of Control and Decision 2023年第2期10卷 150-159页

作者： Arun Sekar Rajasekaran Maria Azees fadi Al-Turjman Department of Electronics and Communication Engineering GMR Institute of TechnologyRajamIndia Artificial Intelligence Engineering Department. Research Center for AI and IoTAI and Robotics InstituteNear East UniversityMersin 10Turkey

Vehicle to grid(V2G)is the most hopeful approach to transfer energy as well as information in the bidirectional way.V2G network is formed by electric vehicles which connect with smart metres for information and energy transfer in a wireless *** though many security preserving schemes developed in V2G networks,they were prone to enormous number of security breaches.A countless deal of works has been done towards it,but security mechanisms in V2G networks are not *** survey work provides a summary about the V2G network characteristics,significance,security services and the security ***,this work offers a summary of some foremost security attacks on various security services such as accessibility,confidentiality,authentication,integrity and non-repudiation and the related countermeasures to make the V2G communications more protected.

关键词： Authentication confidentiality integrity privacy security

Computer-aided Detection of Tuberculosis from Microbiological and Radiographic Images

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Data Intelligence 2023年第4期5卷 1008-1032页

作者： Abdullahi Umar Ibrahim Ayse Gunnay Kibarer fadi Al-Turjman Department of Biomedical Engineering Near East UniversityNicosiaMersin 10Turkey Research Center for Al and loT Faculty of EngineeringUniversity of KyreniaMersin 10Turkey Artificial Intelligence Engineering Dept. Al and Robotics InstituteNear East UniversityMersin 1Turkey

Tuberculosis caused by Mycobacterium tuberculosis have been a major challenge for medical and healthcare sectors in many underdeveloped countries with limited diagnosis *** can be detected from microscopic slides and chest X-ray but as a result of the high cases of tuberculosis,this method can be tedious for both Microbiologists and Radiologists and can lead to *** challenges can be solved by employing Computer-Aided Detection(CAD)via Al-driven models which learn features based on convolution and result in an output with high *** this paper,we described automated discrimination of X-ray and microscope slide images into tuberculosis and non-tuberculosis cases using pretrained AlexNet *** study employed Chest X-ray dataset made available on Kaggle repository and microscopic slide images from both Near East University Hospital and Kaggle *** classification of tuberculosis using microscopic slide images,the model achieved 90.56%accuracy,97.78%sensitivity and 83.33%specificity for 70:30 *** classification of tuberculosis using X-ray images,the model achieved 93.89%accuracy,96.67%sensitivity and 91.11%specificity for 70:30 *** result is in line with the notion that CNN models can be used for classifying medical images with higher accuracy and precision.

关键词： Tuberculosis Deep Learning Pretrained AlexNet Chest X-ray Microscopic slide