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Papillary fistulotomy vs conventional cannulation for endoscopic biliary access:A prospective randomized trial

World Journal of Gastroenterology 2018年第16期24卷 1803-1811页

作者： Carlos Kiyoshi Furuya Paulo Sakai fabio ramalho tavares marinho Jose Pinhata Otoch Spencer Cheng Lívia Lemes Prudencio Eduardo Guimaraes Hourneaux de Moura Everson Luiz de Almeida Artifon Department of Gastrointestinal Endoscopy Unit University of Sao PauloSao Paulo 05409001Brazil Department of Surgery University of Sao PauloSao Paulo 05403000Brazil Department of Gastroenterology and Radiology University of Sao PauloSao Paulo 04107-030Brazil

AIM To compare the cannulation success, biochemical profile, and complications of the papillary fistulotomy technique vs catheter and guidewire standard access.METHODS From July 2010 to May 2017, patients were prospectively randomized into two groups: Cannulation with a catheter and guidewire(Group Ⅰ) and papillary fistulotomy(Group Ⅱ). Amylase, lipase and C-reactive protein at T0, as well as 12 h and 24 h after endoscopic retrograde cholangiopancreatography, and complications(pancreatitis, bleeding, perforation) were recorded.RESULTS We included 102 patients(66 females and 36 males, mean age 59.11 ± 18.7 years). Group Ⅰ and Group Ⅱ had 51 patients each. The successful cannulation rates were 76.5% and 100%, respectively(P = 0.0002). Twelve patients(23.5%) in Group Ⅰ had a difficult cannulation and underwent fistulotomy, which led to successful secondary biliary access(Failure Group). The complication rate was 13.7%(2 perforations and 5 mild pancreatitis) vs 2.0%(1 patient with perforation and pancreatitis) in Groups Ⅰ and Ⅱ, respectively(P = 0.0597). CONCLUSION Papillary fistulotomy was more effective than guidewire cannulation, and it was associated with a lower profile of amylase and lipase. Complications were similar in both groups.

关键词： Catheterization Complications Endoscopic retrograde cholangiopancreatography Therapeutic use Common bile duct

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Comparison between endoscopic sphincterotomy vs endoscopic sphincterotomy associated with balloon dilation for removal of bile duct stones:A systematic review and meta-analysis based on randomized controlled trials

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World Journal of Gastrointestinal Endoscopy 2018年第8期10卷 130-144页

作者： Cesar Capel de Clemente Junior Wanderley Marques Bernardo Tomazo Prince Franzini Gustavo Oliveira Luz Marcos Eduardo Lera dos Santos Jonah Maxwell Cohen Diogo Turiani Hourneaux de Moura Fábio ramalho tavares marinho Martin Coronel Paulo Sakai Eduardo Guimaraes Hourneaux de Moura Gastrointestinal Endoscopy Unit Department of GastroenterologyUniversity of Sao Paulo Medical SchoolSao Paulo 05403-010Brazil Beth Israel Deaconess Medical Center Harvard Medical SchoolBostonMA 02215United States

AIM To compare gallstones removal rate and incidence of bleeding, pancreatitis, use of mechanical lithotripsy, cholangitis and perforation between isolated sphincterotomy vs sphincterotomy associated with balloon dilation of papilla in choledocholithiasis through the meta-analysis of randomized clinical trials. METHODS We conducted a systematic review according to the PRISMA guidelines. Literature search was restricted to randomized controlled trials(RCTs) on Med Line, Cochrane Library, LILACS, and EMBASE database platforms in July 2017. The manual search included references of retrieved articles. We extracted data focusing on outcomes: The primary endpoint was the stones removal rate; Secondary endpoints were rates of pancreatitis, bleeding, use of mechanical lithotripsy(ML), perforation and cholangitis. RESULTS Eleven RCTs with 1824 patients were included. EST was associated with more post-endoscopic retrograde cholangiopancreatography(ERCP) bleeding [FE RD-0.02, CI(-0.03,-0.00), I2 = 33%, P = 0.05] and more need of mechanical lithotripsy in general [RE RD-0.16, CI(-0.25,-0.06), I2 = 90%, P = 0.002] and in subgroup analysis of stones greater than 15 mm [RE RD-0.20, CI(-0.38,-0.02), I2 = 82%, P = 0.003]. Incidence of pancreatitis [FE RD-0.01, CI(-0.03, 0.01), I2 = 0, P = 0.36], cholangitis [FE RD-0.00, CI(-0.01, 0.01), I2 =0, P = 0.97] and perforation [FE RD-0.01, CI(-0.01, 0.00), I2 = 0, P = 0.23] was similar between the groups as well as similar stone removal rates in general [FE RD-0.01, CI(-0.01, 0.04), I2 = 0, P = 0.23] and pooled analysis of stones greater than 15 mm [FE RD-0.02, CI(-0.02, 0.07), I2 = 11%, P = 0.31]. CONCLUSION Through meta-analysis of randomized clinical trials we found that isolated sphincterotomy was associated with more post-ERCP bleeding and more need for mechanical lithotripsy. However, there was no statistical difference in the stone removal rate between isolated sphincterotomy and sphincterotomy associated with balloon dilation in the approach to remove gallstones.

关键词： Sphincterotomy Papillotomy Dilation Cholangiopancreatography Endoscopic retrograde Endoscopic retrograde cholangiopancreatography Cholangiography

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Infestation of Diatraea saccharalis(Fabr.)during Five Consecutive Cycles of Sugarcane Crop Succeeding Leguminous Crops

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Agricultural Sciences 2015年第1期6卷 14-21页

作者： Edmilson Jose Ambrosano Andre Luiz Lourencao Elaine Bahia Wutke Fabricio Rossi fabio Luis Ferreira Dias Silvio tavares Glaucia Maria Bovi Ambrosano Department of Regional Center South Pole APTA/Agronomic Institute of Campinas/IACPiracicabaBrazil Department of Plant Diseases APTA/Agronomic Institute of Campinas/IACCampinasBrazil Department of Grains and Fibers APTA/Agronomic Institute of Campinas/IACCampinasBrazil Department of Biosystem Engineering University of Sao Paulo/FZEAPirassunungaBrazil Department of Social Dentistry University of Campinas/FOPPiracicabaBrazil

The area cultivated with sugarcane in Brazil is expanding, and increasingly using legumes cover crop in new deployed areas and in those which were reformed. Long-term trials were carried out in Piracicaba, Sao Paulo, Brazil, to evaluate the effect of leguminous green manure on the natural infestation of Diatraea saccharalis (Fabr.) during five cropping cycles of sugarcane “IAC 87-3396”. This study was carried out from October 1999 to October 2005 in Piracicaba, Sao Paulo, Brazil, at coordinates 22°42''S and 47°38''W, 560 m above sea level, in soil classified as Typic Paleudult. Green manure crops were assigned to five treatments: peanuts (Arachis hypogaea L.) (cultivar “IAC-Tatu” and “IAC-Caiapó”), sunn hemp (Crotalaria juncea L.) (cultivar “IAC 1”) and velvet-bean [Mucuna aterrima (Piper & Tracy) Holland] (cultivar “common”). A treatment without any green manure or weed was used as the control. The previous sugarcane crop was destroyed and the soil was prepared in a conventional way (using plow and harrow) before the leguminous crops were sowed. Thirty days after the sowing, weeds were removed and, 120 days later, the crops were cut and its biomass was deposited on the soil surface without incorporation. Experimental plots comprised five rows of sugarcane, each one measuring 10 m long and spaced 1.40 m apart. The sugarcane was harvested 18 months after biomass deposit, on October 25th, 2001 and its stalks were collected at intervals of approximately 12 months in: 07/09/2002, 08/01/2003, 11/07/2004 and 10/06/2005. At harvest, the masses were determined from a sample of sugarcane, cut from three rows (2 m long) in the center of the plot. The losses caused by the sugarcane borer were estimated by the intensity of the infestation by randomly observing and collecting sugarcane stems from each plot. A great reduction in the number of stalks and in the yield was noted proportionally to the intensity of the infestation of the borer in the sugarcane crop grown after the velvet-bean. The sugarcane-velvet-bean rotation sho

关键词： Arachis hypogaea L. Crotalaria juncea L. Mucuna aterrima(Piper&Tracy)Holland Saccharum spp. Sugarcane Borer

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Optimal photonic indistinguishability tests in multimode networks

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Science Bulletin 2018年第22期63卷 1470-1478页

作者： Niko Viggianiello Fulvio Flamini Marco Bentivegna Nicolò Spagnolo Andrea Crespi Daniel J.Brod Ernesto F.Galvao Roberto Osellame fabio Sciarrino Dipartimento di Fisica Sapienza Universitadi RomoPiazzale Aldo Moro 51-00185RomaItaly Istituto di Fotonica e Nanotecnologie Consiglio Nazionale delle Ricerche (IFN-CNR)Piazza Leonardo da Vinci321-20133 MilanoItaly Diportimento di Fisica Politecnico di MilanoPiazza Leonardo da Vinci321-20133 MilanoItaly Perimeter Institute for Theoretical Physics 31 Caroline Street NorthWaterlooON N2L 2Y5Canada Instituto de Pisica Universidade Federal FluminenseAv.Gal.Milton Tavares de Souza s/nNiteroiRJ 24210-340Brazil

Particle indistinguishability is at the heart of quantum statistics that regulates fundamental phenomena such as the electronic band structure of solids, Bose-Einstein condensation and superconductivity.Moreover, it is necessary in practical applications such as linear optical quantum computation and simulation, in particular for Boson Sampling devices.It is thus crucial to develop tools to certify genuine multiphoton interference between multiple sources.Our approach employs the total variation distance to find those transformations that minimize the error probability in discriminating the behaviors of distinguishable and indistinguishable photons.In particular, we show that so-called Sylvester interferometers are near-optimal for this task.By using Bayesian tests and inference, we numerically show that Sylvester transformations largely outperform most Haar-random unitaries in terms of sample size required.Furthermore, we experimentally demonstrate the efficacy of the transformation using an efficient 3 D integrated circuits in the single-and multiple-source cases.We then discuss the extension of this approach to a larger number of photons and modes.These results open the way to the application of Sylvester interferometers for optimal assessment of multiphoton interference experiments.

关键词： Particle indistinguishability Quantum statistics Optical quantum computation Quantum simulation Sylvester interferometers Bayesian tests Multiphoton interference experiments

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Oral Health and Masticatory Performance in Adults Submitted to Bariatric Surgery: A Pilot Study

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Open Journal of Stomatology 2015年第3期5卷 87-93页

作者： Paula Valeska tavares Aline Coelho Micheline Coelho ramalho Vasconcelos Criseuda Maria Benício Barros Rosa Maria Mariz Melo Sales Marmhoud Coury Armiliana Soares Nascimento Maria da Conceicao de Barros Correia Luciana de Barros Correia Fontes Fundacao de Ensino Superior de Olinda(Funeso Unesf) OlindaBrazil Instituto de Medicina Integral Professor Fernando Figueira(Imip) RecifeBrazil Universidade Estadual da Paraiba(UEPB) Campina GrandeBrazil Universidade de Pernambuco(UPE) CamaragibeBrazil Universidade Federal de Pernambuco(UFPE) RecifeBrazil

Background: Obesity has reached epidemic patterns and constitutes a serious public health problem due to comorbidities and the impact on life quality of affected individuals. Bariatric surgery appears as one of the most recommended treatments;however much has been known about the effects of this intervention on the functional performance of the organism as a whole. Objective: To characterize the oral health of adults submitted to bariatric surgery, before and after the intervention, with emphasis on the performance of masticatory function. Methods: A prospective observational cohort study conducted in a public reference service to the treatment of obesity in the city of Recife, State of Pernambuco. The data were obtained during the first half of 2011, through interview, intraoral physical examination and evaluation of masticatory function. Statistical treatment adopted was a CI of 95% and the chi-square test. The collection was conducted in three stages, with initial assessment in the preoperative and follow-up at 60 and 180 days. Results: The sample consisted of 20 volunteers, aged between 23 and 58 years and mean BMI of 43.2 ± 2.8. When compared the pre-operative to the control periods, there were significant differences for variables with decreased tendency towards spontaneous gingival bleeding and increased tooth hypersensitivity and tooth mobility (p < 0.05). Regarding the masticatory function, we found significant differences for most of the variables investigated, except in the coordination of movements and breathing during this function. Conclusion: The performance of masticatory function shows differences in pre- and postoperative periods for bariatric surgery.

关键词： Obesity Bariatric Surgery Oral Health

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Characteristics of Students in Three Schools of General Education and Council of Christian Churches of Angola in the City of Huambo-Angola on Sexuality for Educational Intervention

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Open Journal of Obstetrics and Gynecology 2016年第10期6卷 572-587页

作者： Natércia Paulina S. de Almeida Carolina Lino da Silva José R. Molina Garcia Alberto Capoco Sachiteque Welema Cipriano da Fonseca Carla ramalho Frederico João Carlos Juliana Cezaltina Naduva Kahuli Hamilton dos Prazeres tavares Central Hospital of Huambo Huambo Angola Medical School University of Porto Porto Portugal Huambo Provincial Department of Health Huambo Angola Medical School UniversityJose Eduardo dos Santos Huambo Angola Municipal Hospital of Caála Medical School University José Eduardo dos Santos Huambo Angola

Sexual education is a social responsibility and is a part of the coherent strategy referred to the introduction in schools in Angola. It was made of a prospective, descriptive and longitudinal study that has been characterized the knowledge of sexual education of students in general education in three schools and the Council of Christian Churches in Huambo-Angola in July 2015. The sample consisted of 386 students chosen randomly;there are no sexual education programs in the education system, there are taboos on sexuality, the respondents do not know the sexual organs and much less contraceptive methods, there are still taboos in sexuality theme approach with adolescents, the results showed.

关键词： Characterization Students Schools Knowledge Sexuality

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Adaptation to Long-Term Rainfall Variability for Robusta Coffee Cultivation in Brazilian Southeast

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American Journal of Climate Change 2018年第4期7卷 487-504页

作者： Lima Deleon Martins Fernando Coelho Eugenio Wagner Nunes Rodrigues Sebastiao Vinicius Batista Brinati Tafarel Victor Colodetti Bruno Fardim Christo Dionicio Belisario Luis Olivas fabio Luiz Partelli Jose Francisco Teixeira do Amaral Marcelo Antonio Tomaz Jose Domingos Cochicho ramalho Alexandre Rosa dos Santos Center of Agrarian Sciences and Engineering Federal University of Espirito Santo—CCAE/UFESAlegreBrazil Geotechnology Applied to Global Environment—CNPq Advanced Research Group—GAGEN AlegreBrazil Federal University of Santa Maria Santa MariaBrazil Jose Faustino Sanchez Carrion National University HuachoPeru North University Center Federal University of Espirito Santo—CUNES/UFESSao MateusBrazil Plant-Environment Interactions&Biodiversity Lab(Plant Stress&Biodiversity) Linking LandscapeEnvironmentAgriculture and Food(LEAF)Dept.Recursos NaturaisAmbiente e Territorio(DRAT)Instituto Superior de Agronomia(ISA)Universidade de Lisboa(ULisboa)Quinta do MarquesOeirasPortugal

Coffee is one of the world most traded agricultural commodities. Currently, a lot of attention has been on Robusta coffee (Coffea canephora Pierre ex A. Froehner) because it seems to evidence a greater tolerance to extreme climatic events than Arabica coffee (C. arabica L.). Despite this, only a few works have been developed aimed at discriminating the climatic vulnerability in regions which prioritize robust coffee production. The aim of this work was to analyze historical climatic variables in space and time for the characterization of climatic vulnerability of micro-regions, in search of mitigation and adaptation, which might support the improvement of production systems of C. canephora coffee trees. The case study was carried out for one of the largest production regions of Robusta coffee of the world, in Brazil, geographically located between the 39°38' and 41°50' West longitude meridians and the 17°52' and 21°19' South latitude parallels. The vulnerability was characterized by the spatial and temporal variation of rainfall and rainfall seasonal pattern (based on 30 years of historical data), elements of climatic water balance, elevation and area planted with Robusta coffee. The choice of mitigation and adaptation were based on widely validated criteria. Overall, the results show that the vulnerability of Robusta coffee is related to low index of rainfall, the rainfall seasonability and the water deficiency. In the studied region, there is approximately 42% of some type of water vulnerability during the year, with a severe to medium scale;this vulnerability is very pronounced in regions farther away from the coast of the Atlantic Ocean, since for a year approximately 92% of them are water deficient. In addition, the data show that this distance from the ocean implies a reduction of 75% in the phases of water surplus not only. The strategies of greater potential for adaptation and mitigation are related to the planting of improved genotypes, utilization of polycultures systems, increasing plant density, the i

关键词： Coffea canephora Rainfall Climate Change Shade Irrigation

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使用酪蛋白磷酸肽-无定形磷酸钙（CPPACP）改良新型夜间牙齿漂白术的初步临床报告

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中国口腔医学继续教育杂志 2012年第5期15卷 294-298页

作者： Boniek Castillo Dutra Borges Adriana Alcantara Meira de Vasconselos Ana Gabriela Gama Cunha fabio Henrique de SaLeitao Pinheiro Claudia tavares Machado Alex Jose Souza dos Santos 刘若宇(译) 不详南方医科大学口腔医学院 510515

尽管指导性的夜间漂白术美白牙齿的功效已得到了充分肯定，然而却通常伴随着矿物质的丢失和牙齿敏感的问题。目前的研究报告介绍了一款新型的再矿化剂，同时推荐一项指导性的．可降低牙齿敏感性的夜间活髓牙漂白技术。将22％过氧化脲凝... 详细信息

尽管指导性的夜间漂白术美白牙齿的功效已得到了充分肯定，然而却通常伴随着矿物质的丢失和牙齿敏感的问题。目前的研究报告介绍了一款新型的再矿化剂，同时推荐一项指导性的．可降低牙齿敏感性的夜间活髓牙漂白技术。将22％过氧化脲凝胶与含有酪蛋白磷酸肽一无定形磷酸钙的MIPaste相混合。取过氧化物与MIPaste各1mI混合直至形成均质的糊剂。嘱5名患者接受进行3周的家庭漂白术治疗。通过Vitapan比色等级体系从视觉上直观地评估其治疗效果。所有患者在接受漂白治疗后均显示：降低了至少2个单位的VitaPan等级．且未出现敏感症状。MIPaste与过氧化物的共同使用并不会对凝胶的效能产生影响．且仍能有效降低其敏感性。

关键词：无定形磷酸钙酪蛋白磷酸肽牙齿漂白术临床报告过氧化脲凝胶牙齿敏感性改良过氧化物

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