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Evaluation of Mineral Elements Content of Senegal Fruits

Journal of Minerals and Materials Characterization and Engineering 2022年第2期10卷 163-173页

作者： Rokhaya Sylla Gueye Jérôme Ledauphin fabienne baraud Lydia Leleyter Mélanie Lemoine Rokhaya Gueye Adama Diedhiou Mamadou Balde Nango Gaye Matar Seck Djibril Fall Alassane Wele Laboratoire de Chimie Physique Minérale Organique et Thérapeutique Université Cheikh Anta Diop (UCAD) Dakar Sénégal Unité de Recherche “Aliments Bioprocédés Toxicologie Environnement” Université de Caen Normandie Caen France Laboratoire de Chimie Analytique et Bromatologie (UCAD) Dakar Sénégal

This study determined mineral value and antioxidant activity of Senegal fruits for contributing to improving healthy diet and preventing some chronic diseases. Mineral element contents of Dialium guineense, Landolphia heudelotti, Mangifera indica, Cyperus esculentus and Saba senegalensis, which are widely available and consumed, were studied. The results by ICP-OES spectrophotometry after acid mineralization showed highest levels of (per 100 g fruits), calcium (158 mg), potassium (1018 mg), magnesium (532 mg), zinc (26 mg) with juice of Landolphia heudelotti fruit pulp. Mangifera indica pulp is richer in sodium (89 mg), phosphorus (556 mg), sulphur (384 mg) and silicon (110 mg). Dialium senegalensis pulp is richer in iron (23 mg) and manganese (19 mg). Lyophilized Cyperus esculentus rhizomes analyzed by atomic absorption spectrophotometry gave highest concentrations of (per 100 g fruits), calcium (2550 mg), potassium (11,843 mg) and magnesium (7669 mg) but sodium content (22 mg) is lower. In vitro antioxidant activity evaluation with the DPPH radical showed for 10 mg/ml concentration, highest inhibition percentage for Saba senegalensis 4.03%, followed by Landolphia heudelotti and Dialium guineense, which were significantly similar 2.29% and 2.20% respectively, Mangifera indica 1.7% and finally Cyperus esculentus 0.5%, but much lower compared to the ascorbic acid equal to 96.32% used as a reference.

关键词： Fruits Senegal Mineral Elements Antioxidant Activity

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Production of micro-cuttings from acorns to test the plasticity of response to contrasting soil water regimes

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Journal of Forestry Research 2016年第5期27卷 995-1001页

作者： julien parelle sara belabbes fabienne tatin-froux UMR Chrono-Environnement 6249 Universite de Bourgogne Franche-Comte/CNRS USC INRA 16 route de Gray 25030 Besancon Cedex France

We collected acorns from selected Quercus robur and Quercus petraea mother trees growing at sta- tions with different depths to the water table. We produced pairs of micro-cuttings from these single acorns. The obtained pairs of cuttings represented phenotypes of high similarity according to photosynthetic parameters. These pairs of cuttings were used to test the plasticity of response to contrasting water regimes. For each pair, one cutting was submitted to drought and the other was submitted to waterlogging. Drought response was recorded according to gas exchange traits （stomatal closure and water use effi- ciency）. The response to waterlogging was recorded according to the capacity to form hypertrophied lenticels and to maintain the CO2 assimilation rate. Intermediary phenotypes presenting both high water use efficiency and the capacity to develop hypertrophied lenticels were expected.

关键词： Acorns Drought petraea Quercus sessiliflora Quercus robur Quercus Waterlogging

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Specialized or opportunistic how does the high mountain endemic butterfly Erebia nivalis survive in its extreme habitats？

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Insect Science 2018年第1期25卷 161-171页

作者： Stefan Ehl Vivian Dalstein fabienne Tull Patrick Gros Thomas Schmitt Biogeography Trier University Trier Germany Haus der Natur Salzburg Department Entomology Salzburg Austria Senckenberg German Entomological Institute Department Taxonomy and Biogeography Muncheberg Germany Entomology Department of Zoology Institute of Biology Martin Luther University Halle-Wittenberg Halle (Saale) Germany

High mountain ecosystems are a challenge for the survival of animal and plant species, which have to evolve specific adaptations to cope with the prevailing extreme conditions. The strategies to survive may reach from opportunistic to highly adapted traits. One species successfully surviving under these conditions is the here studied butterfly Erebia nivalis. In a mark-release-recapture study performed in the Hohe Tauern National Park （Austria） from 22 July to 26 August 2013, we marked 1386 individuals and recaptured 342 of these. For each capture event, we recorded the exact point of capture and various other traits （wing conditions, behavior, nectar sources）. The population showed a partial protandrous demography with the minority of males emerging prior to the females, but the majority being synchronized with them. Males and females differed significantly in their behavior with males being more flight active and females nectaring and resting more. Both sexes showed preferences for the same plant species as nectar sources, but this specialization apparently is the result of a rapid individual adaptation to the locally available flowers. Estimates of the realized dispersal distances predicted a comparatively high amount of long-distance flights, especially for females. Therefore, the adaptation of Erebia nivalis to the unpredictable high mountain conditions might be a mixture of opportunism and specialized traits.

关键词： alpine butterflies movement patterns nectar sources opportunistic behavior partial protandry population demography

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Computer animations of color markings revealthe function of visual threat signals inNeolamprologus pulcher

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Current Zoology 2017年第1期63卷 45-54页

作者： Valentina BALZARINI Michael TABORSKY fabienne VILLA Joachim G. FROMMEN Institute of Ecology and Evolution Behavioral Ecology Division University of Bern Wohlenstrasse 50a 3032Hinterkappelen Switzerland

Visual signals, including changes in coloration and color patterns, are frequently used by animalsto convey information. During contests, body coloration and its changes can be used to assess anopponent＇s state or motivation. Communication of aggressive propensity is particularly importantin group-living animals with a stable dominance hierarchy, as the outcome of aggressive inter-actions determines the social rank of group members. Neolamprologus pulcher is a cooperativelybreeding cichlid showing frequent within-group aggression. Both sexes exhibit two vertical blackstripes on the operculum that vary naturally in shape and darkness. During frontal threat displaysthese patterns are actively exposed to the opponent, suggesting a signaling function. To investi-gate the role of operculum stripes during contests we manipulated their darkness in computeranimated pictures of the fish. We recorded the responses in behavior and stripe darkness of testsubjects to which these animated pictures were presented. Individuals with initially darker stripeswere more aggressive against the animations and showed more operculum threat *** stripes of test subjects became darker after exposure to an animation exhibiting a paleoperculum than after exposure to a dark operculum animation, highlighting the role of the dark-ness of this color pattern in opponent assessment. We conclude that （i） the black stripes on theoperculum of N. pulcherare a reliable signal of aggression and dominance, （ii） these markings playan important role in opponent assessment, and （iii） 2D computer animations are well suited to elicitbiologically meaningful short-term aggressive responses in this widely used model system ofsocial evolution.

关键词： aggression, agonistic behavior, animated pictures, cichlid fish, communication, cooperation, social, threat display.

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Single-cell approaches to investigate B cells and antibodies in autoimmune neurological disorders

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Cellular & Molecular Immunology 2021年第2期18卷 294-306页

作者： Alicia Zou Sudarshini Ramanathan Russell C.Dale fabienne Brilot Brain Autoimmunity Group Kids Neuroscience CentreKids Research at the Children’s Hospital at WestmeadSydneyNSWAustralia Discipline of Child and Adolescent Health Faculty of Medicine and HealthThe University of SydneySydneyNSWAustralia Brain and Mind Centre The University of SydneySydneyNSWAustralia School of Medical Sciences Discipline of Applied Medical ScienceFaculty of Medicine and HealthThe University of SydneySydneyNSWAustralia

Autoimmune neurological disorders,including neuromyelitis optica spectrum disorder,anti-N-methyl-D-aspartate receptor encephalitis,anti-MOG antibody-associated disorders,and myasthenia gravis,are clearly defined by the presence of autoantibodies against neurological *** these autoantibodies have been heavily studied for their biological activities,given the heterogeneity of polyclonal patient samples,the characteristics of a single antibody cannot be definitively *** review details the findings of polyclonal serum and CSF studies and then explores the advances made by single-cell technologies to the field of antibody-mediated neurological ***-resolution single-cell methods have revealed abnormalities in the tolerance mechanisms of several disorders and provided further insight into the B cells responsible for autoantibody ***,several factors,including epitope specificity and binding affinity,finely regulate the pathogenic potential of an autoantibody,and a deeper appreciation of these factors may progress the development of targeted immunotherapies for *** options.

关键词： B cells Recombinant antibodies Autoimmunity Central nervous system Neurological disorders Monoclonal Single cell Sequencing Pathogenicity Epitope Affinity B cell tolerance

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Assessment of diaphragmatic function by ultrasonography:Current approach and perspectives

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World Journal of Clinical Cases 2020年第12期8卷 2408-2424页

作者： Alain Boussuges Sarah Rives Julie Finance fabienne Brégeon Institut de Recherche Biomédicale des Armées ERRSOToulon 83800France Center for Cardiovascular and Nutrition Research(C2VN) Aix Marseille UniversitéINSERM(1260)INRAE(1263)Toulon 83800France Service d’Explorations Fonctionnelles Respiratoires CHU NordAssistance Publique des Hôpitaux de Marseille et Aix Marseille UniversitéIRDAPHMMEPHIIHU-Méditerranée InfectionMarseille 13015France

This article reports the various methods used to assess diaphragmatic function by *** excursions of the two hemidiaphragms can be measured using two-dimensional or M-mode ultrasonography,during respiratory maneuvers such as quiet breathing,voluntary sniffing and deep *** the zone of apposition to the rib cage for both hemidiaphragms,it is possible to measure the thickness on expiration and during deep breathing to assess the percentage of thickening during *** two approaches make it possible to assess the quality of the diaphragmatic function and the diagnosis of diaphragmatic paralysis or *** methods are particularly useful in circumstances where there is a high risk of phrenic nerve injury or in diseases affecting the contractility or the motion of the diaphragm such as neuro-muscular *** methods such as speckle tracking imaging and ultrasound shear wave elastography should provide more detailed information for better assessment of diaphragmatic function.

关键词： Ultrasound Hemidiaphragm Motion Thickness Paralysis Dysfunction Two-dimensional mode M-mode Speckle tracking imaging Ultrasound shear wave elastography

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New tools for optimizing fluid resuscitation in acute pancreatitis

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World Journal of Gastroenterology 2014年第43期20卷 16113-16122页

作者： Perrine Bortolotti fabienne Saulnier Delphine Colling Alban Redheuil Sebastien Preau Critical Care Center University Hospital of Lille59037 LilleFrance Laboratoire de Physiologie EA 4484Lille Nord de France University59037 LilleFrance Cardiovascular Imaging Pitié Salpêtrière Hospital Institute of Cardiology75013 ParisFrance Sorbonne Universités Laboratoire d’Imagerie Biomédicale75005 ParisFrance Université Pierre et Marie Curie-Paris 6 75005 ParisFrance ICAN Imaging Core Lab 75005 ParisFrance

Acute pancreatitis(AP)is a frequent disease with degrees of increasing severity responsible for high *** continuous improvement in care,mortality remains *** hypovolemia,together with microcirculatory dysfunction lead to poor outcome,fluid therapy remains a cornerstone of the supportive ***,poor clinical evidence actually support the aggressive fluid therapy recommended in recent guidelines since available data are *** management remains unclear and leads to current heterogeneous *** strategies may help to improve fluid resuscitation in *** one hand,integration of fluid therapy in a global hemodynamic resuscitation has been demonstrated to improve outcomein surgical or septic *** fluid administration after early identification of patients with high-risk of poor outcome presenting inadequate tissue oxygenation is a major part of this *** the other hand,new decision parameters have been developed recently to improve safety and efficiency of fluid therapy in critically ill *** this review,we propose a personalized strategy integrating these new concepts in the early fluid management of *** new approach paves the way to a wide range of clinical studies in the field of AP.

关键词： Pancreatitis Fluid Passive leg raising Preload Central venous pressure

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Morphological studies of rose prickles provide new in sights

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Horticulture Research 2021年第1期8卷 2849-2860页

作者： Ningning Zhou fabienne Simonneau Tatiana Thouroude Laurence Hibrand-Saint Oyant Fabrice Foucher Univ Angers Institut AgroINRAEIRHSSFR QUASAVF-49000 AngersFrance National Engineering Research Center for Ornamental Horticulture Flower Research Institute(FRI)Yunnan Academy of Agricultural SciencesKunming 650231China Univ Angers INRAESFR QUASAVF-49000 AngersFrance

Prickles are common structures in plants that play a key role in defense against *** the Rosa genus,prickles are widely present with great diversity in terms of form and *** cut rose production,prickles represent an important issue,as they can damage the flower and injure *** objectives were to precisely describe the types of prickles that exist in roses,their tissues of origin and their *** performed a detailed histological analysis of prickle initiation and development in a rose F1 *** on the prickle investigation of 110 roses,we proposed the fi rst categorization of prickles in the Rosa *** are mainly divided into two categories,nonglandular prickles(NGPs)and glandular prickles(GPs),and subcategories were defined based on the presence/absence of hairs and *** demonstrated that NGPs and GPs both originate from multiple cells ofthe ground meristem beneath the *** GPs,the gland cells originate from the protoderm of the GP at the early developmental *** findings clearly demonstrate that prickles are notmodified trichomes(which originate from the protoderm).These conclusions are different from the current mainstream *** results provide a foundation for further studies on prickle initiation and development in plants.

关键词： beneath origin Morphological

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Developing Rational Empathy in Health Care Policy:The Usefulness of Online Comments

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外国语文研究（辑刊） 2021年第1期 29-51页

作者： fabienne Baider University of Cyprus

Studies of interactions have gained an increasing importance in research related to *** empirical studies have explored the dynamics of exchanges between patients and practitioners(Barry et al.,2001,Beach et al.,2001).This study is devoted to the analysis of discussions in two forums to investigate how to develop what we call‘a rational empathy’so as to understand the attitudes and beliefs which constitute the basis of these opinions.

关键词： rational empathy health care policy online comments

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Optic nerve injury-induced regeneration in the adult zebrafish is accompanied by spatiotemporal changes in mitochondrial dynamics

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Neural Regeneration Research 2023年第1期18卷 219-225页

作者： An Beckers Luca Masin Annelies Van Dyck Steven Bergmans Sophie Vanhunsel Anyi Zhang Tine Verreet fabienne EPoulain Karl Farrow Lieve Moons Neural Circuit Development and Regeneration Research Group Animal Physiology and Neurobiology SectionDepartment of BiologyKatholieke Universiteit LeuvenLeuvenBelgium Poulain Lab Department of Biological SciencesUniversity of South CarolinaColumbiaSCUSA Neuro-Electronics Research Flanders Vlaams Instituut voor Biotechnologie(VIB)LeuvenBelgium Leuven Brain Institute LeuvenBelgium Imec LeuvenBelgium

Axonal regeneration in the central nervous system is an energy-intensive *** contrast to mammals,adult zebrafish can functionally recover from neuronal *** raises the question of how zebrafish can cope with this high energy *** previously showed that in adult zebrafish,subjected to an optic nerve crush,an antagonistic axon-dendrite interplay exists wherein the retraction of retinal ganglion cell dendrites is a prerequisite for effective axonal *** postulate a‘dendrites for regeneration’paradigm that might be linked to intraneuronal mitochondrial reshuffling,as ganglion cells likely have insufficient resources to maintain dendrites and restore axons ***,we characterized both mitochondrial distribution and mitochondrial dynamics within the different ganglion cell compartments(dendrites,somas,and axons)during the regenerative *** nerve crush resulted in a reduction of mitochondria in the dendrites during dendritic retraction,whereafter enlarged mitochondria appeared in the optic nerve/tract during axonal *** dendritic regrowth in the retina,mitochondrial density inside the retinal dendrites returned to baseline ***,a transient increase in mitochondrial fission and biogenesis was observed in retinal ganglion cell somas after optic nerve *** together,these findings suggest that during optic nerve injury-induced regeneration,mitochondria shift from the dendrites to the axons and back again and that temporary changes in mitochondrial dynamics support axonal and dendritic regrowth after optic nerve crush.

关键词： axonal regeneration central nervous system dendrite remodeling energy metabolism fission mitochondria mitochondrial trafficking optic nerve crush retina zebrafish

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