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学龄儿童恒牙非创伤性充填远期疗效的临床观察

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中华口腔医学杂志 2004年第1期39卷 34-37页

作者：胡德渝万呼春刘红春李雪范旭 Edward C.m.lo 四川大学华西口腔医学院预防医学教研室成都610041 香港大学牙医学院

目的　评价非创伤性充填 (ArT)治疗恒牙龋的长期效果。方法　采用ArT标准器械和步骤 ,用高强度玻璃离子材料对 197名 12～ 13岁儿童完成充填。连续 6年进行临床评价 ,用美国公共卫生服务标准 (USPHS)同时验证。并用标准rheinberger测量... 详细信息

目的　评价非创伤性充填 (ArT)治疗恒牙龋的长期效果。方法　采用ArT标准器械和步骤 ,用高强度玻璃离子材料对 197名 12～ 13岁儿童完成充填。连续 6年进行临床评价 ,用美国公共卫生服务标准 (USPHS)同时验证。并用标准rheinberger测量器评价充填的磨损程度。结果第 6年小Ⅰ类洞充填的保留率为 75 % ,大Ⅰ类洞充填保留率为 6 1% ,差异有统计学意义 (P m ,明显高于以后每年的磨损值 2 0～ 2 5 μm(P rT充填恒牙龋是适合、有效和可接受的 ,其保留率与洞型大小有关 ,是一种有前途的治疗方法。

关键词：学龄儿童恒牙龋病非创伤性充填远期疗效玻璃离聚物粘固剂龋齿

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Wettability of silicon carbide ceramic by Al_2O_3/Dy_2O_3 and Al_2O_3/Yb_2O_3 systems

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Journal of rare Earths 2013年第6期31卷 634-638页

作者： J.A.da Silva B.m.moreschi G.C.r.Garcia S.ribeiro department of materials Engineering (demAr) Engineering School of Lorena (EEL)Pólo Urbo IndustrialGleba AI6CP 11612608-970LorenaSPBrazil

Wettability is an important phenomenon in the liquid phase sintering of silicon carbide （SiC） ceramics. This work involved a study of the wetting of SiC ceramics by two oxide systems, Al2O3 /Dy2O3 and Al2O3 /Yb2O3, which have so far not been studied for application in the sintering of SiC ceramics. Five mixtures of each system were prepared, with different compositions close to their respective eutectic ones. Samples of the mixtures were pressed into cylindrical specimens, which were placed on a SiC plate and subjected to temperatures above their melting points using a graphite resistance furnace. The behavior of the melted mixtures on the SiC plate was observed by means of an imaging system using a CCD camera and the sessile drop method was em.loyed to determine the contact angle, the parameter that measures the degree of wettability. The results of variation in the contact angle as a function of temperature were plotted in graphic form which showed that the curves displayed a fast decline and good spreading. All the samples of the two systems presented final contact angles of 40o to 10o indicating their good wetting on SiC in the argon atmosphere. The melted/solidified area and interface between SiC and melted/solidified phase were evaluated by scanning electron microscopy （SEm） and their crystalline phases were identified by X-ray diffraction （DrX）. The DrX analysis showed that Al2O3 and rE2O3 reacted and formed the Dy3Al5O12 （DyAg） and Yb3Al5O12 （YbAg） phases. The results indicated that the two systems had a promising potential as additives for the sintering of SiC ceramics.

关键词： liquid-phase sintering silicon carbide rare earth oxide wettability contact angle

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Occurrence of pharmaceuticals and perfluorinated compounds and evaluation of the availability of reclaimed water in Kinmen

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Emerging Contaminants 2016年第3期2卷 135-144页

作者： Webber Wei-Po Lai Yen-Ching Lin Hsin-Hsin Tung Shang-Lien lo Angela Yu-Chen Lin Graduate Institute of Environmental Engineering National Taiwan University71-Chou-shan RoadTaipei106Taiwan

Emerging contaminants have commonly been observed in environmental waters but have not been included in water quality assessments at many locations around the *** evaluate the availability of reclaimed water in Kinmen,Taiwan,this study provides the first survey of the distribution of thirty-three pharmaceuticals and five perfluorinated chemicals in lake waters and water from.local wastewater treatment plants(WWTPs).The results showed that the target emerging contaminants in Kinmen lakes were at trace ng/L *** addition,most of the target compounds were present in the Jincheng and Taihu WWTP influents at ng/L concentrations levels,of which 5 compounds(erythromycin-H2O(1340 ng/L),ibuprofen(1763 ng/L),atenolol(1634 ng/L),acetaminophen(2143 ng/L),and caffeine(3113 ng/L))reached mg/L *** overall treatment efficiencies of the Jincheng and Taihu WWTPs with respect to these pharmaceuticals and perfluorinated chemicals were poor;half of the compounds were less than 50%*** compounds(sulfamethoxazole,erythromycin-H2O,clarithromycin,ciprofloxacin and ofloxacin)with risk quotient(rQ)values>1 in the effluent should be further investigated to understand their effects on the aquatic *** and advanced treatment units are found necessary to provide high-quality recycled water and sustainable water resources.

关键词： Emerging contaminant Perfluorinated compound Pharmaceutical Water scarcity Wastewater treatment plant

How Secure Having IoT devices in Our Homes?

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Journal of Information Security 2020年第2期11卷 81-91页

作者： debora Estrada lo’ai Tawalbeh robert Vinaja department of Computing and Cyber Security Texas A&M University San Antonio Texas USA

Nowadays, technology has evolved to be in our daily lives to assist in making our lives easier. We now have technology helping us in our lives at home. devices used to create our “smart home” have done a great deal in making our lives at home less burdensome, but sadly, these devices have secured our personal lives to be more accessible to outsiders. In this paper, the security of home smart devices and their communication will be researched by using other academic articles to support facts found. The operation of the devices will be discussed along with security risks and future trends on security attacks. The results found will be crucial to knowing exactly how well our own home is protected. After understanding where the risks lie and a demonstration of how hackers can take control of our smart home, solutions will be given to shield ourselves from security attacks. We protect our homes from physical threats by locking doors, but it is time we guard ourselves from cyber threats as well.

关键词： IoT Smart Home Cloud

Cardiopulmonary changes in patients with sickle cell anemia:A systematic review

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World Journal of Hematology 2022年第3期9卷 20-29页

作者： Jamile Silva lopes Ícaro Garcia Viana maria Luísa Cordeiro Santos fa.rício freire de m.lo márcio Vasconcelos Oliveira Cláudio Lima Souza Instituto multidisciplinar em Saúde Universidade Federal da BahiaVitória da Conquista 45029-094BahiaBrazil

BACKGrOUND Given the high prevalence of cardiovascular and pulmonary abnormalities associated with sickle cell anemia(SCA),the clinical impact caused in addition to compromising the quality of life of patients and the overcharge that it represents to the public health system,this study systematized and evaluated scientific publications on pulmonary complications and cardiovascular diseases in sickle cell patients from 1920 to *** compilation aims to provide knowledge for health professionals and managers in order to draw attention to the importance of chronic diseases in SCA patients and in addition to providing elements that provide improvements in management of useful resources that contribute to improve the quality and increase the life expectancy of these *** To systematically compile information about cardiopulmonary changes in patients with *** A systematic literature review was performed based on the PrISmA recommendation including scientific articles indexed in the Scientific Electronic Library Online databases of the United States National Library of medicine and Biblioteca Virtual de Saú*** search period was delimited between 1990 and 2020 and selected in Portuguese,English and *** sets of descriptors were used for each database including research carried out with human *** reading the articles,those useful for this review were extracted using a collection instrument designed for this *** The final selection included 27 *** year with the highest number of publications was 2016 with 5 studies(18.51%),followed by 2017 with 4(14.81%).The type of study most carried out in the period was cohort 10(37.03%)followed by cross-sectional and case-control with 8 studies in each(29.62%).regarding the language of publication,the distribution was as follows:25(92.59%)in English,1(3.70%)in Spanish and 1(3.70%)in *** The findings of the present study suggest that cardiopulmonary alterations

关键词： Sickle cell anemia Cardiopulmonary alterations Clinical profile Systematic review

Prader-Willi Syndrome:16-Year Experience in Hong Kong

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Journal of Genetics and Genomics 2012年第4期39卷 191-194页

作者： Ivan F.m. lo Ho ming Luk luksite@*** Tony m.F. Tong Kent K.S. Lai Daniel H.C. Chan Albert C.F. Lam David K.H. Chan Edgar W.L. Hau Connie O.Y. Fung Stephen T.S. Lam Clin Genet Serv Dept Hlth Kowloon Hong Kong Peoples R China

Prader-Willi syndrome （PWS） is an important, well-recognized syndromic form of neurodevelopmental disorder. The incidence is about 1 in 15,000-25,000 live births, and it affects both males and females （Vogels et al... 详细信息

关键词： PWS Prader-Willi Syndrome

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Diversity of Arbuscular mycorrhizal Fungi Species Associated with Soybean (Glycine max L. merill) in Benin

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American Journal of Plant Sciences 2022年第5期13卷 686-701页

作者： Howell B. Houngnandan Appolinaire Adandonon Trévis S. B. Adoho Leslie D. r. Bossou Adélaïde H. fagnibo Oslo S. Gangnon moriaque Akplo Charlotte m. Zoundji Félix Kouèlo Adolphe Zeze Pascal Houngnandan Laboratoire des Sciences Végétale Horticole et Forestière (LaSVHF) Université Nationale d’Agriculture (UNA) Kétou République du Bénin Laboratoire de microbiologie des Sols et d’Ecologie microbienne Faculté des Sciences Agronomiques de l’Université d’Abomey-Calavi (UAC) Abomey-Calavi République du Bénin Laboratoire de Biotechnologies Végétale et microbienne Unité Mixte de Recherche et d’Innovation en Sciences Agronomiques et Génie Rural Institut National Polytechnique Felix Houphou&#235 t-Boigny (INPHB C&#244 te d’Ivoire) Yamoussoukro C&#244 te d’Ivoire Ecole de Gestion et de Production Vegetale et Semenciere (EGPVS) Université Nationale d’Agriculture (UNA) Kétou République du Bénin

Arbuscular mycorrhizal Fungi (AmFs) could be used to sustainably improve crop yields. The present study evaluated the diversity of AmF species associated with soybean (Glycine max L. merill) in main soybean-producing areas in Benin. Composite soil samples from 13 production areas at a rate of 04 villages per production areas were collected. A spore trapping device was set up to reveal the diversity of spores. The physical and chemical properties of the soils, the frequency and intensity of mycorrhization of roots, and the diversity of AmF spores were determined in the soil samples following trapping. As result, eight morphotypes belonging to four genera: Glomus, Acaulospora Gigaspora and Disversispora and three families: Diversisporales, Glomérales and Paraglomérales were observed. An important variability of spore densities was observed from one production areas to another with a higher abundance in the production areas of Copargo estimated at 3584 spores/100g soil. The biological diversity indexes as Shannon (0.0311), Simpson (0.0204) and Hill (0.0235), varied significantly (p rom one production areas to another. There was significant correlation between the parameters studied, particularly between the physico-chemical parameters of the soils and between the physico-chemical parameters and the biological diversity indexes. For the mycorrhization parameters, the mycorhization frequencies did not vary from one production areas to another, unlike the intensities, which significantly varied from one production areas to another (2.31% to 24.62%). Finally, this study revealed that the physico-chemical parameters of the soils had an influence on the other parameters studied. moreover, there were an abundance and a significant diversification of AmFs associated with soybean in the different production areas, which are influenced by certain physico-chemical soil parameters.

关键词： Arbuscular mycorrhizal Fungi (AmFs) Soybean Spore density Diversity

Investigational growth factors utilized in animal models of spinal fusion: Systematic review

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World Journal of Orthopedics 2019年第4期10卷 176-191页

作者： Ethan Cottrill A Karim Ahmed Noah Lessing Zachary Pennington Wataru Ishida Alexander Perdomo-Pantoja Sheng-fu lo Elizabeth Howell Christina Holmes C rory Goodwin Nicholas Theodore Daniel m Sciubba Timothy F Witham department of Neurosurgery The Johns Hopkins Hospital department of Neurosurgery Duke University Medical Center

BACKGrOUND Over 400000 Americans annually undergo spinal fusion surgeries, yet up to 40%of these procedures result in pseudoarthrosis even with iliac crest autograft, the current "gold standard" treatment. Tissue engineering has the potential to solve this problem via the creation of bone grafts involving bone-promoting growth factors(e.g., bone morphogenetic protein 2). A broad assessment of experimental growth factors is important to inform future work and clinical potential in this area. To date, however, no study has systematically reviewed the investigational growth factors utilized in preclinical animal models of spinal *** To review all published studies assessing investigational growth factors for spinal fusion in animal models and identify promising agents for *** We conducted a systematic review of the literature using Pubmed, Embase,Cochrane Library, and Web of Science databases with searches run on may 29 th,2018. The search query was designed to include all non-human, preclinical animal models of spinal fusion reported in the literature without a timespan limit. Extracted data for each model included surgical approach, level of fusion,animal species and breed, animal age and sex, and any other relevant characteristics. The dosages/sizes of all implant materials, spinal fusion rates,and follow-up time points were recorded. The data were analyzed and the results reported in tables and text. PrISmA guidelines were followed for this systematic *** Twenty-six articles were included in this study, comprising 14 experimental growth factors: AB204(n = 1); angiopoietin 1(n = 1); calcitonin(n = 3);erythropoietin(n = 1); basic fibroblast growth factor(n = 1); growth differentiation factor 5(n = 4), combined insulin-like growth factor 1 +transforming growth factor beta(n = 4); insulin(n = 1); NELL-1(n = 5); noggin(n= 1); P-15(n = 1); peptide B2 A(n = 2); and secreted phosphoprotein 24(n = 1).The fusion rates of the current gold sta

关键词： Spinal fusion Growth factor Pseudoarthrosis Systematic review

microfluidic actuators based on temperature-responsive hydrogels

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microsystems & Nanoengineering 2018年第1期4卷 534-540页

作者： loïc D'Eramo Benjamin Chollet marie Leman Ekkachai martwong mengxing Li Hubert Geisler Jules Dupire margaux Kerdraon Clémence Vergne fa.rice monti Yvette Tran Patrick Tabeling mmN IPGGMicrofluidiqueMEMSNanostructures(MMN)Institut Pierre-Gilles de Gennes(IPGG)GulliverEcole Supérieure de Physique et Chimie Industrielles(ESPCI Paris)PSL Research University10 rue VauquelinParis 75005France SImm ESPCI ParisSciences et Ingénierie de la Matière Molle(SIMM)Ecole Supérieure de Physique et Chimie Industrielles(ESPCI Paris)PSL Research University10 rue VauquelinParis 75005France microfactory 8 rue Jean CalvinParis 75005France

The concept of using stimuli-responsive hydrogels to actuate fluids in microfluidic devices is particularly attractive,but limitations,in terms of spatial resolution,speed,reliability and integration,have hindered its development during the past two *** patterning and grafting poly(N-isopropylacrylamide)PNIPAm hydrogel films on plane substrates with a 2μm horizontal resolution and closing the system afterward,we have succeeded in unblocking bottlenecks that thermo-sensitive hydrogel technology has been challenged with until *** this paper,we demonstrate,for the first time with this technology,devices with up to 7800 actuated micro-cages that sequester and release solutes,along with valves actuated individually with closing and opening switching times of 0.6±0.1 and 0.25±0.15 s,*** applications of this technology are illustrated in the domain of single cell handling and the nuclear acid amplification test(NAAT)for the Human Synaptojanin 1 gene,which is suspected to be involved in several neurodegenerative diseases such as Parkinson’s *** performance of the temperature-responsive hydrogels we demonstrate here suggests that in association with their moderate costs,hydrogels may represent an alternative to the actuation or handling techniques currently used in microfluidics,that are,pressure actuated polydimethylsiloxane(PDmS)valves and droplets.

关键词： actuator high throughput hydrogel microfluidics single cell valve