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Intraorbital wooden foreign bodies: case series and literature review

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International Journal of Ophthalmology(English edition) 2021年第10期14卷 1619-1627页

作者： ya-yan You Bing-Jie Shi Xin-yan Wang Jin Chen Zheng-Rong Wang Xing-Hua Wang fa.gang Jiang Department of Ophthalmology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022Hubei ProvinceChina

Intraorbital wooden foreign bodies(IOWFBs) constitute a relatively rare ocular trauma, which occupy a special type of intraorbital foreign bodies(IOFBs). Data regarding IOWFBs must be obtained from case reports or small case series due to their rarity. Here, we reported 5 cases of IOWFBs and reviewed the related literatures, which could provide comprehensive information regarding the clinical manifestations, diagnosis, and surgical treatment of IOWFBs. Combined with the published literature, a total of 51 independent cases were counted after we added 5 cases. Among them, the number of male and female patients was 35 and 16 respectively;the mean age was 27.3±18.2(range 1-66)y. Obviously, the disorder seemed to occur mainly in young and middle-aged people. Because of the diversity in the clinical manifestations and imaging characteristics of IOWFBs, misdiagnosis and missed diagnosis often occur during the initial visit. Delayed diagnosis may lead to a high risk of orbital infection caused by IOWFBs. Surgery is the treatment of choice for most patients;however, the missed diagnosis and residue of foreign bodies after previous surgery cannot be ignored. Therefore, an accurate diagnosis is governed by the detailed trauma history, careful ocular examination, close observation of clinical manifestations, correct imaging diagnosis [e.g., magnetic resonance imaging(MRI) or computerized tomography(CT)], and timely and completely elimination of IOWFBs.

关键词： orbit foreign body wooden trauma infection

No-tillage with straw mulching boosts wheat grain yield by improving the eco-physiological characteristics in arid regions

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Journal of Integrative Agriculture 2023年第11期22卷 3416-3429页

作者： YIN Wen fa. Zhi-long HU fa.long fa. Hong HE Wei SUN ya-li WANg Feng ZHAO Cai YU Ai-zhong CHAI Qiang State Key Laboratory of Aridland Crop Science Lanzhou 730070P.R.China College of Agronomy Gansu Agricultural UniversityLanzhou 730070P.R.China

Straw returning to the field is a technical measure of crop production widely adopted in arid areas. It is unknown whether crop yield can be further increased by improving the eco-physiological characteristics when straw returning is applied in the crop production system. So, a three-year field experiment was conducted with various straw returning treatments for wheat production:(i) no-tillage with straw mulching(NTSM),(ii) no-tillage with straw standing(NTSS),(iii) conventional tillage with straw incorporation(CTS), and(iv) conventional tillage with no straw returning(CT, control). The eco-physiological and yield formation indicators were investigated to provide the basis for selecting the appropriate straw returning method to increase wheat yield and clarifying its regulation mechanism on eco-physiology. The results showed that NTSM and NTSS treatments had better regulation of eco-physiological characteristics and had a higher yield increase than CTS and CT. Meanwhile, NTSM had a relatively higher yield than NTSS through better regulation of eco-physiological characteristics. Compared to CT, the leaf area index of NTSM was decreased by 6.1–7.6% before the Feekes 10.0 stage of wheat, but that of NTSM was increased by 38.9–45.1% after the Feekes 10.0 stage. NTSM effectively regulated the dynamics of the photosynthetic source of green leaves during the wheat growth period. NTSM improved net photosynthetic rate by 10.2–21.4% and 11.0–21.6%, raised transpiration rate by 4.4–10.0% and 5.3–6.1%, increased leaf water use efficiency by 5.6–10.4% and 5.4–14.6%, at Feekes 11.0 and 11.2 stages of wheat, compared to CT, respectively. NTSM had higher leaf water potential(LWP) by 7.5–12.0% and soil water potential(SWP) by 8.9–24.0% from Feekes 10.3 to 11.2 stages of wheat than CT. Meanwhile, the absolute value of difference on LWP and SWP with NTSM was less than that with CT, indicating that NTSM was conducive to holding the stability of water demand for wheat plants and water s

关键词： straw soil grain

Synthesis and Antibacterial Activities of 1,4-Disubstituted Phenyl-5-(halo-2-hydroxyphenyl)imino-1,2,3-triazole

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Chemical Research in Chinese Universities 2012年第3期28卷 424-429页

作者： ZHAO Xu LU Jun-rui XIN Chun-wei LU Bo-wei BAO Xiu-rong LI Jian-fa.LIU ya ya.g Xu-yun YUAN Yi College of Chemistry and Chemical Engineering Tianjin University of TechnologyTianjin 300384P.R.China College of Chemistry Nankai UniversityTianjin 300071P.R.China

According to the superposition principle of reinforcement of biological activities, 24 novel 1,4- disubstituted phenyl-5-（halo-2-hydroxyphenyl）imino-l,2,3-triazoles was synthesized and characterized by 1H NMR, ^13C NMR, elemental analysis and IR. All the target compounds were screened for their antibacterial potential in vitro against Monilia albican, Escherichia coli and Staphylococcus aureus. It was shown that all the compounds possessed efficient antibacterial activities at a concentration of 0.1 mg/mL, even at a concentration of 0.01 mg/mL, some of the compounds still exhibited antibacterial activities against Escherichia coli and Monilia albican. At last, the struc- ture-activity relationship was discussed based on the antibacterial results.

关键词： 1,4-Disubstituted phenyl-5-(halo-2-hydroxyphenyl)imino-l,2,3-triazole Antibacterial activity Structure-activity relationship

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研发背景高管权力与企业脱虚向实

软科学 2024年第6期38卷 137-143页

作者：李梦晓董雅浩贺晨彭博成都理工大学商学院成都3610059

利用手工收集的沪深A股上市公司年报中高管团队排名数据,实证检验了研发背景高管的权力增加能否促进企业脱虚向实。结果表明,研发背景高管在团队中的权力越大,企业金融化的程度越低,这一结论在控制内生性问题后仍然成立。机制检验发现,... 详细信息

利用手工收集的沪深A股上市公司年报中高管团队排名数据,实证检验了研发背景高管的权力增加能否促进企业脱虚向实。结果表明,研发背景高管在团队中的权力越大,企业金融化的程度越低,这一结论在控制内生性问题后仍然成立。机制检验发现,研发背景高管权力是通过提高研发投入和降低代理成本来降低企业金融化。进一步分析表明,研发背景高管权力促进企业脱虚向实的积极作用在高新技术企业中更显著.

关键词：高管权力企业金融化代理成本企业创新

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Optical state selection process with optical pumping in a cesium atomic fountain clock

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Chinese Physics B 2021年第8期30卷 269-274页

作者： Lei Han fa.g fa.g Wei-Liang Chen Kun Liu ya-Ni Zuo fa.Song Zheng Shao-ya.g Dai Tian-Chu Li School of Optics and Photonics Beijing Institute of TechnologyBeijing 100081China Key Laboratory of Time and Frequency Standards National Institute of Metrology(NIM)Beijing 100029China

We propose and realize a new optical state selection method on a cesium atomic fountain clock by applying a two-laser 3-3'optical pumping configuration to spin polarize *** atoms are prepared in|F=3,mF=0>clock state with optical pumping directly after being launched up,followed by a pushing beam to push away the atoms remaining in the|F=4>*** a state selection efficiency exceeding 92%,this optical method can substitute the traditional microwave state selection,and helps to develop a more compact physical package.A Ramsey fringe has been achieved with this optical state selection method,and a contrast of 90%is obtained with a full width half maximum of 0.92 *** short-term frequency stability of 6.8×10^(-14)(τ/s)^(-1/2) is *** addition,the number of detected atoms is increased by a fa.tor of 1.7 with the optical state selection.

关键词： optical pumping atomic fountain clock spin polarization optical state selection

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铸造工艺数据驱动的工程机械铸件缺陷预测

铸造 2024年第9期73卷 1329-1335页

作者：刘迎辉余朋潘徐政朱守琴计效园吴来发殷亚军沈旭解明国周建新华中科技大学材料成形与模具技术全国重点实验室湖北武汉430074 安徽合力股份有限公司合肥铸锻厂安徽合肥230022

针对砂型铸造过程缺陷难以寻因、工艺数据类别不平衡问题,提出了一种基于特征重分布与代价敏感学习的卷积神经网络缺陷预测方法。首先,根据样本特征相关性,对特征向量排列顺序进行了优化;其次,基于不平衡工艺数据样本设计了代价敏感正则... 详细信息

针对砂型铸造过程缺陷难以寻因、工艺数据类别不平衡问题,提出了一种基于特征重分布与代价敏感学习的卷积神经网络缺陷预测方法。首先,根据样本特征相关性,对特征向量排列顺序进行了优化;其次,基于不平衡工艺数据样本设计了代价敏感正则项,对模型损失函数进行了修正;最后,构建了缺陷预测模型(FR-CS-CNN)。测试结果表明,本研究构建的FR-CS-CNN在总体预测精度上达到了93.67%,相比卷积神经网络提升了2.96%。

关键词：砂型铸造缺陷预测代价敏感学习卷积神经网络

Development and characterization of a novel common wheat–Mexico Rye T1DL·1RS translocation line with stripe rust and powdery mildew resistance

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Journal of Integrative Agriculture 2023年第5期22卷 1291-1307页

作者： LI Jiao-jiao ZHAO Li Lü Bo-ya FU Yu ZHANg Shu-fa.LIU Shu-hui ya.g Qun-hui WU Jun LI Jia-chuang CHEN Xin-hong Shaanxi Key Laboratory of Plant genetic Engineering Breeding College of AgronomyNorthwest A&F UniversityYangling 712100P.R.China

Rye(Secale cereale L., 2n=2x=14, RR) is a significant genetic resource for improving common wheat because of its resistance to multiple diseases and abiotic-stress tolerant traits. The 1RS chromosome from the german cultivated rye variety Petkus is critical in wheat breeding. However, its weakened disease resistance highlights the need to identify new resources. In the present study, a novel derived line called D27 was developed from common wheat and Mexico *** observations characterized the karyotype of D27 as 2n=42=21 Ⅱ. genomic in situ hybridization indicated that a pair of whole-arm translocated Mexico Rye chromosomes were inherited typically in the mitotic and meiosis stages of D27. Experiments using fluorescence in situ hybridization(FISH) and gliadin electrophoresis showed that D27 lacked wheat 1DS chromosomes. They were replaced by 1RS chromosomes of Mexico Rye, supported by wheat simple-sequence repeat markers, rye sequence characterized amplified region markers, and wheat 40K SNP array *** wheat 1DS chromosomes could not be detected by molecular markers and wheat SNP array, but the presence of rye 1RS chromosomes was confirmed. Agronomic trait assessments indicated that D27 had a higher tiller number and enhanced stripe rust and powdery mildew resistance. In addition, dough properties analysis showed that replacing 1DS led to higher viscosity and lower dough elasticity in D27, which was beneficial for cake making. In conclusion, the novel cytogenetically stable common wheat–Mexico Rye T1DL·1RS translocation line D27 offers excellent potential as outstanding germplasm in wheat breeding programs focusing on disease resistance and yield improvement. Additionally,it can be valuable for researching the rye 1RS chromosome’s genetic diversity.

关键词： common wheat disease resistance dough properties rye translocation line

The Experimental Research of the Control System of Flexible Hose Instability

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International Journal of Plant Engineering and Management 2017年第4期22卷 243-249页

作者： WANg Shuai ZHOU Wang-fa.SU ya-yun Institute of Robotics and Intelligent Equipment Tianjin University of Technology and Education

The experimental control system of the superelastic hose instability is based on S7-200PLC as controller. The superelastic hoses are sealed at their both ends. The breakdown condition of that is taken as the object of study under different combined and working conditions. The upper computer of the experimental bench adopts MCgS configuration software. The test of experiment can meet the control and real-time monitoring of experimental platform conditions. In the experiment,we measure and monitor the data of temperature,tensile force,pressure and so on by the analog modules. During the process of experiment,the actuators like the solenoid valve and the motor are controlled by the switch. The paper describes that the constitution of experimental control system of the superelastic hose instability, control function and the achievement of monitoring condition. It is convenient to operate in the control system,the design cost is low,the man-machine interfa.e is simple and understandable,and the experimental control system will be significant in bio-engineering and medical research.

关键词： PLC MCgS superelastic hose experimental control system

新抗原脉冲树突状细胞疫苗在肿瘤免疫治疗中的作用

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解放军医学杂志 2024年第2期49卷 220-228页

作者：王彤昕张凡闫鑫张雅婷李玉民甘肃省消化系肿瘤重点实验室甘肃兰州730030 兰州大学第二医院肿瘤外科甘肃兰州730030

新抗原脉冲树突状细胞疫苗(Neo-DCVac)是一种新型肿瘤免疫治疗手段。新抗原是指肿瘤细胞突变产生的具有较强免疫原性和肿瘤特异性的肽段。Neo-DCVac是基于新抗原被树突状细胞摄取、加工后递呈并激活T细胞引发机体免疫反应,从而发挥抗肿... 详细信息

新抗原脉冲树突状细胞疫苗(Neo-DCVac)是一种新型肿瘤免疫治疗手段。新抗原是指肿瘤细胞突变产生的具有较强免疫原性和肿瘤特异性的肽段。Neo-DCVac是基于新抗原被树突状细胞摄取、加工后递呈并激活T细胞引发机体免疫反应,从而发挥抗肿瘤作用。在高通量测序基础上发展而来的个体化Neo-DCVac有望成为肿瘤精准免疫治疗的新方向。本文从个体化Neo-DCVac构建、在实体瘤中联合治疗的临床应用、适宜接种人群和目前存在的局限性等方面进行综述,旨在为肿瘤免疫治疗的相关研究提供参考。

关键词：新抗原树突状细胞疫苗肿瘤免疫治疗