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Rare Metals 2024年第4期43卷 1786-1792页

作者： Yuan-Feng Xie Xing-cheng Xie Zhong-Wu Li Rui-Jun Cao Zhong-Kun Lin Qing Li chen-Guang Lin Powder Metallurgy and Special Materials Research Department General Research Institute for Nonferrous MetalsBeijing100088China

The effects of cryogenic treatment(CT)and tempering-cryogenic treatment(TCT)on the microstructure and properties of coarse-grained WC-10Co cemented carbides with different carbon contents were *** binder phase,WC mean grain sizes,W solubility in the binder,relative magnetic s aturation,densities,hardness,wear resistance and second phase precipitation of cemented carbides with different heat treatments were *** results show that there are significant changes of microstructure and properties in the samples with CT and TCT,especially due to the precipitation of metastable nanoparticles W_(x)Co_(y)C_(z) in the binder during the heat treatments of CT and *** the simultaneous combination of microstructure and nanoparticle-reinforced binder,a dramatically improved combination of hardness and wear resistance of the samples after TCT has been achieved.

关键词： Cryogenic treatment Tempering Coarsegrained cemented carbide Carbon content Nanoparticlereinforced binder

抗黑色素瘤分化相关基因5抗体相关幼年皮肌炎的临床特征与治疗

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临床儿科杂志 2024年第3期42卷 238-242,258页

作者：张瑾程江闵月宋晓翔封其华苏州大学附属儿童医院风湿免疫科江苏苏州215000

目的总结抗黑色素瘤分化相关基因5抗体(MDA5)相关幼年型皮肌炎(JDM)的临床特征,研究其治疗及评估。方法回顾性分析2019年1月至2022年5月住院的5例抗MDA5相关JDM患儿的基本信息、临床表现、实验室及影像学检查、治疗及预后等临床资料... 详细信息

目的总结抗黑色素瘤分化相关基因5抗体(MDA5)相关幼年型皮肌炎(JDM)的临床特征,研究其治疗及评估。方法回顾性分析2019年1月至2022年5月住院的5例抗MDA5相关JDM患儿的基本信息、临床表现、实验室及影像学检查、治疗及预后等临床资料。结果 5例患儿中男3例、女2例,5例均有典型的高春疹/征,3例有皮肤溃疡表现,2例出现皮肤钙化,1例有指端坏死。5例患儿肌力均正常,但肌肉核磁共振均异常。肌炎特异性抗体均为抗MDA5抗体阳性,3例合并抗Ro-52阳性。5例高分辨CT均示间质性肺病,只有1例出现气促,2例涎液化糖链抗原(KL-6)升高;2例有消化道受累。5例均使用激素,4例使用环磷酰胺作为最初免疫抑制剂,2月内均可部分缓解。结论抗MDA 5相关JDM起病年龄偏小,临床表现以典型皮疹为主,肌肉受累表现不明显,以临床无肌病性皮肌炎为主,并高发间质性肺病;抗MDA5滴度、高分辨CT、KL-6检查对于诊断及疾病疗效评估尤为重要;治疗主要甲基泼尼松龙联合免疫抑制剂,联合托法替布者治疗效果良好。

关键词：抗MDA5抗体幼年皮肌炎临床无肌病性皮肌炎间质性肺病

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砂质海岸底栖硅藻的研究进展

生态科学 2024年第2期43卷 246-252页

作者：陈敏黄国彪戚洪帅刘璇许亚福州大学先进制造学院晋江362251 自然资源部第三海洋研究所厦门361005 自然资源部北部湾滨海湿地生态系统野外科学观测研究站北海536015 上海海洋大学海洋科学学院上海201306

文章综述了国内外关于砂质海岸底栖硅藻的研究进展。作为砂质海岸主要的植物群,底栖硅藻通过一系列机制以适应多变的沙生环境。在潮间带的沉积物中,底栖硅藻是初级生产力和沙滩食物网的重要组成部分。沉积物、温度、盐度、光照、营养盐... 详细信息

文章综述了国内外关于砂质海岸底栖硅藻的研究进展。作为砂质海岸主要的植物群,底栖硅藻通过一系列机制以适应多变的沙生环境。在潮间带的沉积物中,底栖硅藻是初级生产力和沙滩食物网的重要组成部分。沉积物、温度、盐度、光照、营养盐和生物因素等等都会对底栖硅藻的生长和群落分布产生影响。近年来,陆续有了关于我国潮间带底栖硅藻群落分布特征的研究,但总体来说,关于沙生境底栖硅藻的研究相对较少,需要进一步的调查以完善我国的硅藻生态学研究。

关键词：砂质海岸底栖硅藻潮间带

S-scheme heterojunction of crystalline carbon nitride nanosheets and ultrafine WO_(3)nanoparticles for photocatalytic CO_(2)reduction

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Journal of Environmental Sciences 2024年第6期140卷 103-112页

作者： Gongjie chen Ziruo Zhou Bifang Li Xiahui Lin Can Yang Yuanxing fang Wei Lin Yidong Hou Guigang Zhang Sibo Wang State Key Laboratory of Photocatalysis on Energy and Environment College of ChemistryFuzhou UniversityFujian 350116China

Highly crystalline carbon nitride polymers have shown great opportunities in overall water photosplitting;however,their mission in light-driven CO_(2)conversion remains to be *** this work,crystalline carbon nitride(CCN)nanosheets of poly triazine imide(PTI)embedded with melon domains are fabricated by KCl/LiCl-mediated polycondensation of dicyandiamide,the surface of which is subsequently deposited with ultrafine WO_(3)nanoparticles to construct the CCN/WO_(3)heterostructure with a S-scheme *** characterizations have been conducted to reveal the compositions and structures of the S-scheme CCN/WO_(3)hybrid,featuring strengthened optical capture,enhanced CO_(2)adsorption and activation,attractive textural properties,as well as spatial separation and directed movement of light-triggered charge *** mild conditions,the CCN/WO_(3)catalyst with optimized composition displays a high photocatalytic activity for reducing CO_(2)to CO in a rate of 23.0μmol/hr(i.e.,2300μmol/(hr·g)),which is about 7-fold that of pristine CCN,along with a high CO selectivity of 90.6%against ***,it also manifests high stability and fine reusability for the CO_(2)conversion *** CO_(2)adsorption and conversion processes on the catalyst are monitored by in-situ diffuse reflectance infrared Fourier transform spectroscopy(DRIFTS),identifying the crucial intermediates of CO_(2)^(*)-,COOH^(*)and CO^(*),which integrated with the results of performance evaluation proposes the possible CO_(2)reduction mechanism.

关键词： Crystalline carbon nitride Photocatalysis CO_(2)reduction S-scheme WO_(3)

Suppressing the Undesirable Energy Loss in Solution-Processed Hyperfluorescent OLEDs Employing BODIPY-Based Hybridized Local and Charge-Transfer Emitter

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Energy & Environmental Materials 2024年第2期7卷 372-380页

作者： Xuewei Nie Zafar Mahmood Denghui Liu Mengke Li Dehua Hu Wencheng chen Longjiang Xing Shijian Su Yanping Huo Shaomin Ji School of Chemical Engineering and Light Industry Guangdong University of TechnologyGuangzhou 510006China State Key Laboratory of Luminescent Materials and Devices and Institute of Polymer Optoelectronic Materials and Devices South China University of TechnologyGuangzhou 510640China

Hyperfluorescent organic light-emitting diodes(HF-OLEDs)approach has made it possible to achieve excellent device performance and color purity with low roll-off using noble-metal-free pure organic *** significant progress,the performance of HF-OLEDs is still unsatisfactory due to the existence of a competitive dexter energy transfer(DET)*** this contribution,two boron dipyrromethene(BODIPY)-based donor-acceptor emitters(BDP-C-Cz and BDP-N-Cz)with hybridized local and charge transfer characteristics(HLCT)are introduced in the HF-OLED to suppress the exciton loss by dexter mechanism,and a breakthrough performance with low-efficiency roll-off(0.3%)even at high brightness(1000 cd m^(-2))is *** is demonstrated that the energy loss via the DET channel can be suppressed in HF-OLEDs utilizing the HLCT emitter,as the excitons from the dark triplet state of such emitters are funneled to its emissive singlet state following the hot-exciton *** developed HF-OLED device has realized a good maximum external quantum efficiency(EQE)of 19.25%at brightness of 1000 cd m^(-2)and maximum luminance over 60000 cd m^(-2),with an emission peak at 602 nm and Commission International de L'Eclairage(CIE)coordinates(0.57,0.41),which is among the best-achieved results in solution-processed *** work presents a viable methodology to suppress energy loss and achieve high performance in the HF-OLEDs.

关键词： BODIPY hyperfluorescence organic light-emitting diodes solution-process

The Pursuit of Happiness

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China Today 2024年第10期73卷 63-65页

作者： chen SIJIA Hainan Inter-national Media Center based in Haikou

Xinjiang has effectively safeguarded the basic rights of people of all ethnic groups to work and employment,and made great strides in economic and social development,thus significantly improving people’s livelihoods.

关键词： Xinjiang Pursuit employment

Aggressive fluid management may be associated with disease progression in suspected sepsis patients admitted to the intensive care unit: a retrospective cohort study

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World Journal of Emergency Medicine 2024年第1期15卷 52-55页

作者： Miao Bian Zhihao Wang Yanling chen Yue Sun Hongsen Ji Yutao Wang Li Pang Department of Respiratory Qianwei Hospital of Jilin ProvinceChangchun 130012China Department of Geriatrics Jilin Provincial Geriatric Medicine Clinical Research Centerthe First Hospital of Jilin UniversityChangchun 130021China Department of Emergency the First Hospital of Jilin UniversityChangchun 130021China The First Operating Room the First Hospital of Jilin UniversityChangchun 130021China

Sepsis is a lethal condition characterized by multiple organ dysfunction due to disrupted host responses to severe infections.[1]Aff ected patients often have a Sequential Organ failure Assessment(SOfa)score≥2.[2]Patients with a SOfa scorefa(qSOfa)score≥2;(2)SOfa score=1;or(3)National Early Warning Score(NEWS)4-6.[3]Compared with studies on fluid resuscitation in sepsis patients,there are few studies on fluid management in patients with suspected ***,we conducted a retrospective cohort study to evaluate the relationship between fluid management and disease progression in suspected sepsis patients.

关键词： patients sepsis admitted

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炭质板岩冻融后蠕变特性试验及损伤模型研究

公路交通科技 2024年第3期41卷 143-150,162页

作者：刘国民黄梅陈华姬云平四川省长大公路隧道(群)运营安全工程实验室四川成都611130 四川省交通勘察设计研究院有限公司四川成都610017 中铁第一勘察设计院集团有限公司甘肃兰州730000

为了揭示炭质板岩冻融后蠕变力学,以汶川-马尔康高速公路卓克基隧道炭质板岩为研究对象。开展了不同冻融循环次数下的三轴压缩蠕变试验。假设岩石受荷载作用下的时效损伤服从Weibull概率密度分布,由此定义受荷损伤变量,依据唯象损伤力... 详细信息

为了揭示炭质板岩冻融后蠕变力学,以汶川-马尔康高速公路卓克基隧道炭质板岩为研究对象。开展了不同冻融循环次数下的三轴压缩蠕变试验。假设岩石受荷载作用下的时效损伤服从Weibull概率密度分布,由此定义受荷损伤变量,依据唯象损伤力学理论定义冻融损伤变量,考虑冻融与应力的耦合效应,构建冻融、受荷总损伤变量。基于炭质板岩蠕变行为表现,确定H-H|N-N|S蠕变模型结构,基于此进行了损伤演化,得到一个新的可反映冻融与应力耦合的蠕变损伤模型,拓展为三维应力状态。给出模型参数求解方法,并分析了损伤演化规律,采用所建模型识别炭质板岩蠕变数据,引入一个传统模型进行了对比,分析模拟对比曲线,验证新模型的可行性和合理性。结果表明:炭质板岩的蠕变试验曲线呈“台阶形”,轴向应变随着时间增长而递增;随着冻融作用的增强,长期强度随之递减,冻融循环作用可能会降低岩石蠕变破坏的难度;新模型对炭质板岩蠕变行为的模拟效果较好,平均R^(2)达0.9878,证明了新模型描述炭质板岩冻融后蠕变特性的可行性。冻融作用的加强,使得炭质板岩内部结构的损伤发展更快,对岩石蠕变破坏起一定促进作用。

关键词：隧道工程蠕变特性损伤模型炭质板岩冻融损伤变量

mA reader YTHDF2 governs the onset of atrial fibrillation by modulating Cacna1c translation

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Science China Life Sciences 2024年

作者： Chuansheng chen Guanghua Wang Qicheng Zou Ke Xiong Zhiwen chen Beihua Shao Yi Liu Duanyang Xie Yong Ji Key Laboratory of Cardiovascular and Cerebrovascular Medicine Nanjing Medical University State Key Laboratory of Cardiovascular Diseases Shanghai East Hospital School of Medicine Tongji University Department of Pathology and Pathophysiology School of Medicine Tongji University Department of Cardiology School of Medicine Tongji University Shanghai Arrhythmia Research Center Shanghai East Hospital School of Medicine Tongji University

Atrial fibrillation（AF） is the most common arrhythmia, which is tightly associated with the abnormal expression and function of ion channels in the atrial cardiomyocytes. N6-methyladenosine（m6A）, a widespread chemical modification in eukaryotic m RNA, is known to play a significant regulatory role in the pathogenesis of heart disease. However, the significance of m6A regulatory proteins in the onset of AF remains unclear. Here, we demonstrate that the m6A reader protein YTHDF2 regulates atrial electrical remodeling and AF onset by modulating the Cav1.2 expression. Firstly, YTHDF2 expression was selectively upregulated in rat atrial cardiomyocytes with AF. Secondly,YTHDF2 knockout reduced AF susceptibility in mice. Thirdly, the knockout of YTHDF2 increased Cav1.2 protein levels in an m6A-independent manner, ultimately prolonging the atrial myocardial refractory period, a critical electrophysiological substrate for the onset of AF. Fourthly, the N-terminal domain of YTHDF2 was identified as critical for Cacna1c m RNA translation regulation. Overall, our findings unveil that YTHDF2 can alter Cav1.2 protein expression in an m6A-independent manner, thereby facilitating the onset of AF. Our study suggests that YTHDF2 may be a potential intervention target for AF.

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软体机械手关键技术研究进展

科技导报 2024年第8期42卷 48-62页

作者：付敏王鹏王成梦曹众陈见坤东北林业大学机电工程学院哈尔滨150040

软体机械手具有良好的环境适应性、灵活性和人机交互性,可应用于作物采摘、水下探索、医疗康复、野外救援、物品分拣等众多领域。综述了软体机械手的驱动方式、制造技术、构型,以及建模与控制方法等关键技术进展,分析了其目前存在的问... 详细信息

软体机械手具有良好的环境适应性、灵活性和人机交互性,可应用于作物采摘、水下探索、医疗康复、野外救援、物品分拣等众多领域。综述了软体机械手的驱动方式、制造技术、构型,以及建模与控制方法等关键技术进展,分析了其目前存在的问题与难点,提出了未来软体机械手探索方向:制作材料智能化、提高控制精确度、探究新型驱动方式、仿生设计构型。

关键词：软体机械手驱动构型制造技术建模与控制