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No Effects of Meteorological Factors on the SARS-CoV-2 Infection Fatality Rate

Biomedical and Environmental Sciences 2021年第11期34卷 871-880页

作者： SOLANES Aleix LAREDO Carlos GUASP Mar fullana miquel angel FORTEA Lydia GARCIA-OLIVE Ignasi SOLMI Marco SHIN Jae II URRA Xabier RADUA Joaquim Institut d'lnvestigacions Biomediques August Pi i Sunyer(IDIBAPS) BarcelonaSpain Department of Psychiatry and Forensic Medicine Autonomous University of BarcelonaBarcelonaSpain Neurosciences Unit Hospital ClinicBarcelonaSpain Adult Psychiatry and Psychology Department Institute of NeurosciencesHospital ClinicBarcelonaSpain Biomedical Network Research Centre on Mental Health(CIBERSAM) Instituto de Salud Carlos IIIMadridSpain Department of Medicine University of BarcelonaBarcelonaSpain Department of Medicine Autonomous University of BarcelonaBarcelonaSpain Pneumology Department Hospital Germans Trias i PujolBadalonaSpain Neurosciences Department University of PaduaPaduaItaly Padua Neuroscience Center PaduaItaly Department of Psychosis Studies Institute of PsychiatryPsychology and NeuroscienceKing's College LondonLondonUK Department of Pediatrics College of MedicineYonsei UniversitySeoul 03722Korea Centre for Psychiatric Research and Education Department of Clinical NeuroscienceKarolinska InstitutetStockholmSweden

Objective Previous studies have shown that meteorological factors may increase COVID-19 mortality,likely due to the increased transmission of the ***,this could also be related to an increased infection fatality rate(IFR).We investigated the association between meteorological factors(temperature,humidity,solar irradiance,pressure,wind,precipitation,cloud coverage)and IFR across Spanish provinces(n=52)during the first wave of the pandemic(weeks 10–16 of 2020).Methods We estimated IFR as excess deaths(the gap between observed and expected deaths,considering COVID-19-unrelated deaths prevented by lockdown measures)divided by the number of infections(SARS-CoV-2 seropositive individuals plus excess deaths)and conducted Spearman correlations between meteorological factors and IFR across the *** We estimated 2,418,250 infections and 43,237 *** IFR was 0.03%in<50-year-old,0.22%in 50–59-year-old,0.9%in 60–69-year-old,3.3%in 70–79-year-old,12.6%in 80–89-year-old,and26.5%in≥*** did not find statistically significant relationships between meteorological factors and adjusted ***,we found strong relationships between low temperature and unadjusted IFR,likely due to Spain’s colder provinces’aging *** The association between meteorological factors and adjusted COVID-19 IFR is *** age differences or ignoring COVID-19-unrelated deaths may severely bias COVID-19 epidemiological analyses.

关键词： Climate COVID-19 Infection fatality rate SARS-CoV-2 Temperature Weather

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Multi-agent system simulation for urban policy design:open space land use change problem

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International Journal of Modeling, Simulation, and Scientific Computing 2016年第2期7卷 20-37页

作者： Roman Buil miquel angel Piera Egils Ginters Logistics and Aeronautics Unit Universitat Autonoma de Barcelona c.Emprius2 Sabadell 08202Spain Vidzeme University of Applied Sciences Cesu Street 4 Valmiera LV-4201Latvia

Multi-agent system(MAS)models have been increasingly applied to the simulation of complex phenomena in different areas,providing successful and credible *** behavior related to a specific urban activity(i.e.,recreation activities in a park,using bicycle for mobility purposes)can be modeled as an agent(actor)with several affinities and preferences which are dependent on aspects that affect the activity.A particular application of a MAS approach is in area of urban policy design,in which policies should be designed considering citizens needs,preferences and *** an open space in a city is available(i.e.,an industry is moved to an industrial area),a land use policy should contribute to identify the new use for the urban *** are different land use policies that can be applied depending on which services or facilities must be empowered in the *** is important to identify the correct policy in order to satisfy present citizens needs but considering also the future needs in a social changing context.A socio-technological simulation model has been developed to allow citizens to get a better understanding of the urban problem,its dynamics and explore the sustainability of the different solutions.,enhancing citizens to participate in the urban decisions through new technologies(i.e.,e-participation).This paper illustrates an open space MAS simulation model for land use design policies in which citizens can check their opinion and get a better understanding of the different choices and its acceptability by the community considering not only present neighborhood profiles,but also future neighborhood *** is the first step before the development of the final software including a user friendly interface to let citizens with different cultural profiles to perform simulations as an essential and neutral tool to reach consensus during the decision-making process in urban policy design.

关键词： Agent simulation,urban policy open space e-governance e-participation

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Diabetes mellitus, revascularization and outcomes in elderly patients with myocardial infarction-related cardiogenic shock

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Journal of Geriatric Cardiology 2020年第10期17卷 604-611页

作者： miquel Gual Albert Ariza-Solé María García Márquez Cristina Fernández JoséL Bernal Francesc Formiga María-Isabel Barrionuevo JoséC Sánchez-Salado Victòria Lorente Júlia Pascual Isaac Llaó Oriol Alegre angel Cequier Javier Elola Hospital Universitari de Bellvitge L’Hospitalet de LlobregatBarcelonaSpain Fundación Instituto para la Mejora de la Asistencia Sanitaria MadridSpain Hospital Clínico Universitario San Carlos MadridSpain Hospital Universitario 12 de Octubre MadridSpain

Background The prognostic role of diabetes mellitus(DM)in elderly patients with myocardial infarction-related cardiogenic shock(MI-CS)remains *** information exists about the impact of intensive cardiac care unit(ICCU)and revascularization on outcomes of elderly patients with *** aimed to assess the prognostic impact of DM according to age in patients with MI-CS,and to analyze the impact ICCU management and revascularization on in-hospital mortality in MI-CS patients at older *** Discharge episodes with diagnosis of CS associated with MI were selected from the Spanish National Health System’s Basic Data *** were classified according to their availability of *** outcome measured was in-hospital *** A total of 23,590 episodes of MI-CS were identified,of whom 12,447(52.8%)were in patients aged≥75 *** impact of DM on in-hospital mortality was different among age *** in younger patients,DM was associated to a higher mortality risk(0.52 vs.0.47,OR=1.12,95%CI:1.06–1.18,χ^2<0.001),this association became non-significant in older patients(0.76 vs.0.81,χ^2=0.09).Adjusted mortality rate of MI-CS aged≥75 years was lower in patients admitted to hospitals with ICCU(adjusted mortality rate:74.2%vs.77.7%,P<0.001)and in patients undergoing revascularization(74.9%vs.77.3%,P<0.001).Conclusions Prognostic impact of DM in patients with MI-CS was different according to age,with a significantly lower impact at older *** availability of ICCU and revascularization were associated with better outcomes in these complex patients.

关键词： Cardiogenic shock Diabetes mellitus Myocardial infarction Revascularization The elderly

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