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Treatment of Donor-derived Carbapenem-resistant Klebsiella pneumoniae Infection after Renal Transplantation with Tigecycline and Extended-infusion Meropenem

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Current Medical Science 2021年第4期41卷 770-776页

作者： zhi-qiang WANG zhi-liang GUO Hao FENG Cheng fu guang-yuan ZHAO Ke MA Lan ZHU Gang CHEN Institute of Organ Transplantation Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department of Infectious Disease Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Key Laboratory of Organ Transplantation Ministry of EducationMinistry of Public HealthChinese Academy of Medical SciencesWuhan 430030China

Objective Donor-derived carbapenem-resistant Klebsiella pneumoniae(CRKP)infection has recently emerged as a critical early complication after renal *** CRKP is usually sensitive to tigecycline,monotherapy with this drug is often less than *** investigated the efficacy of a combined regimen of tigecycline with high-dose,extended-infusion meropenem in the treatment of donor-derived CRKP infection after kidney *** From Jan.2016 to Dec.2017,a total of 12 CRKP isolates were detected from cultures of the organ preservation solution used for soaking the donor kidneys at our *** or possible donor-derived infection(DDI)was identified in 8 transplant *** data were retrospectively *** Klebsiella pneumoniae carbapenemase-2(KPC-2)-producing CRKP was reported to be positive in organ preservation solution cultures at 3.5±0.9 days after transplantation,leading to surgical site(n=3),urinary tract(n=4),and/or bloodstream(n=2)infections in 8 *** drug susceptibility tests showed that CRKP was sensitive to tigecycline,but resistant to *** 7 patients who received tigecycline combined with high-dose extended-infusion meropenem,DDIs were successfully *** length of hospital stay was 31(18–129)days,and the serum creatinine at discharge was 105.8±16.7µmol/*** one remaining patient who received tigecycline combined with intravenous-drip meropenem died of septic shock.A median follow-up of 43 months(33–55)showed no recurrence of new CRKP infection in the 7 surviving *** It was suggested that a prompt and appropriate combination therapy using tigecycline with high-dose extended-infusion meropenem is effective in treating donor-derived KPC-2-producing CRKP infection after renal transplantation.

关键词： renal transplantation donor-derived infection carbapenem-resistant Klebsiella pneumoniae tigecycline meropenem

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White Noise Approach to The Construction of Φ_4~4 Quantum Fields(Ⅱ)

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Acta Mathematica Sinica,English Series 2007年第5期23卷 895-904页

作者： guang Lin RANG zhi Yuan HUANG College of Mathematics and Statistics Wuhan University Wuhan 430072 P. R. China Department of Mathematics Hubei University Wuhan 430062 P. R. China Department of Mathematics Huazhong University of Science and Technology Wuhan 430074 P. R. China

In this paper a complete proof for the existence of generalized operators satisfying abstract 02 dynamical equations of quantum motions δ^2/δt^2Ф（t, x）＋（ △- m^2）Ф（t, x） = -λ ：Ф^3（t, x）, subject to a suitable initial condition, is given under the framework of white noise analysis. Also some important commutation relations related to Ф44 quantum fields are discussed and proved in detail.

关键词： White noise calculus Generalized operator Ф4 4 quantum fields

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Persistent Spin Current in a Hard-Wall Confining Quantum Wire with Weak Dresselhaus Spin-Orbit Coupling

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Communications in Theoretical Physics 2009年第2期51卷 341-344页

作者： fu Xi ZHOU guang-Hui Department of Physics Hunan Normal University Changsha 410081 China Department of Electronics and Physics Hunan College of Science and Technology Yongzhou 425100 China

We investigate theoretically the spin current in a quantum wire with weak Dresselhaus spin-orbit coupling connected to two normal conductors. Both the quantum wire and conductors are described by a hard-wall confining potential. Using the electron wave-functions in the quantum wire and a new definition of spin current, we have calculated the elements of linear spin current density j^Ts,xi and j^Ts,yi（i=x, y, z）. We find that the elements j^Ts,xx and j^Ts,yy have a antisymmetrical relation and the element j^Ts,yz has the same amount levelas j^Ts,xx and j^Ts,yy. We also find a net linear spin current density, which has peaks at the center of quantum wire. The net linear spin current can induce a linear electric field, which may imply a way of spin current detection.

关键词： quantum wire Dresselhaus spin-orbit coupling spin current

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Spin Accumulation in a Rashba Nanoribbon

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Communications in Theoretical Physics 2009年第7期52卷 159-162页

作者： fu Xi ZHOU guang-Hui Department of Physics Hunan Normal University Changsha 410081 China Department of Electronics and Physics Hunan University of Science and Engineering Yongzhou 425100 China

We investigate theoretically the spin accumulation in a Rashba spin-orbit coupling (SOC) nanoribbon nonadiabatically connected to a normal *** the nanoribbon and conductor are described by a hard-wall confining *** the scattering matrix approach within the effective free-electron approximation,we have calculated the out-of-plane spin accumulation in the *** is found that the spin accumulation shifts toward the two edges of nanoribbon with the increasing of propagation ***,as the Rashba SOC strength increases the spin accumulation in the nanoribbon will be enhanced and this result may suggest us a simple method to control the spin accumulation of the system by Rashba SOC strength.

关键词： nanoribbon Rashba spin-orbit coupling spin accumlation

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Formulations of a hydromechanical interface element

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Acta Mechanica Sinica 2011年第5期27卷 697-705页

作者： Zhong-zhi fu Si-Hong Liu College of Water Conservancy and Hydropower Engineering Hohai University 210098 Nanjing China

A hydromechanical interface element is proposed for the consideration of the hydraulic-mechanical coupling effect along the *** fully coupled governing equations and the relevant finite element formulations are derived in detail for the interface *** the involved matrices are of the same form as those of a solid element,which makes the incorporation of the model into a finite element program *** examples are then numerically simulated using the interface *** results confirm the correctness of the proposed model and motivate its application in hydromechanical contact problems in the future.

关键词： Hydromechanical interface element · Coupling effect · Finite element · Contact problem

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Design,fabrication and kinematics of a bio-inspired robotic bat wing

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Science China(Technological Sciences) 2016年第12期59卷 1921-1930页

作者： YIN Dong fu ZHANG zhi Sheng School of Mechanical Engineering Southeast University

The current work is oriented toward the development of a novel biologically inspired bat aerial robot with morphing wings. Based on the flight characteristics data of natural bats(Eptesicus fuscus), a novel four degrees of freedom robotic bat wing was developed to emulate the movements of bat wing. The design, fabrication, programing and wind tunnel experiments of the robot bat wing are described in this paper. Based on this robotic wing, the influence of flap amplitude, wind speed, flight frequency, downstroke ratio and stroke plane angle as well as the contributions of flap, elbow, sweep and wrist motions on the aerodynamic force and mechanical power were studied and analyzed. Results of wind tunnel experiments validated that higher lift would bring greater power consumption, and the flap motion would generate the most force and need more energy expenditure compared with other motions of bat. The experimental results suggest that the flap and fold motions are indispensable to make a robotic bat wing that has a better flight performance. This study provides some implications and a better understanding for the future robotic bat.

关键词： bio-inspiration wing robotic bat flight kinematics wrist motion

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Multivariate statistical analysis for the surface water quality of the Luan River,China

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2009年第1期10卷 142-148页

作者： zhi-wei ZHAO fu-yi CUI State Key Laboratory of Urban Water Resource and Environment Harbin Institute of Technology Harbin 150090 China

In order to analyze the characteristics of surface water resource quality for the reconstruction of old water treatment plant,multivariate statistical techniques such as cluster analysis and factor analysis were applied to the data of Yuqiao Reservoir-surface water resource of the Luan River,*** results of cluster analysis demonstrate that the months of one year were divided into 3 groups and the characteristic of clusters was agreed with the seasonal characteristics in North *** factors were derived from the complicated set using factor *** 1 included turbidity and chlorophyll,which seemed to be related to the anthropogenic activities;factor 2 included alkaline and hardness,which were related to the natural characteristic of surface water;and factor 3 included Cl and NO2-N affected by mineral and agricultural *** sinusoidal shape of the score plots of the three factors shows that the temporal variations caused by natural and human factors are linked to seasonality.

关键词： Surface water quality Cluster analysis Factor analysis Temporal variation of scores

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Jackson's Theorem on Bounded Symmetric Domains

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Acta Mathematica Sinica,English Series 2007年第8期23卷 1391-1404页

作者： Ming zhi WANG guang Bin REN School of Science Huzhou Teachers College Huzhou 313000 P. R. China Department of Mathematics University of Science and Technology of China Hefei 230026 P. R. China

Polynomial approximation is studied on bounded symmetric domain Ω in C^n for holomorphic function spaces X such as Bloch-type spaces, Bergman-type spaces, Hardy spaces, Ω algebra and Lipschitz space. We extend the classical Jackson＇s theorem to several complex variables：Eκ（f,X）≤ω（1/k,f,X）, where Eκ（f,X） is the deviation of the best approximation of f ∈X by polynomials of degree at most k with respect to the X-metric and ω（1/k,f,X） is the corresponding modulus of continuity.

关键词： bounded symmetric domains Bergman spaces polynomial approximation

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Use of Dispersion Relations in ππ and KK^- Coupled-Channel System

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Communications in Theoretical Physics 2007年第4X期48卷 685-694页

作者： XIAO zhi-guang ZHENG Han-Qing Department of Physics Peking University Beijing 100871 China

Systematic and careful studies are made on the properties of the IJ =00 7rTr and KK^- coupled-channel system, using newly derived dispersion relations between the phase shifts and poles and cuts. The effects of nearby... 详细信息

关键词： ππ scattering

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Wind tunnel simulation of wind loading on a solid structure of revolution

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Acta Mechanica Sinica 2010年第4期26卷 551-558页

作者： Le-Tian Yang zhi-fu Gu State Key Laboratory of Turbulence and Complex Systems and College of Engineering Peking University 100871 Beijing China

The wind tunnel simulations of wind loading on a solid structure of revolution with one smooth and five rough surfaces were conducted using wind tunnel tests. Timemean and fluctuating pressure distributions on the surface were obtained, and the relationships between the roughness Reynolds number and pressure distributions were analyzed and discussed. The results show that increasing the surface roughness can significantly affect the pressure distribution, and the roughness Reynolds numbers play an important role in the change of flow patterns. The three flow patterns of subcritical, critical and supercritical flows can be classified based on the changing patterns of both the mean and the fluctuating pressure distributions. The present study suggests that the wind tunnel results obtained in the supercritical pattern reflect more closely those of full-scale solid structure of revolution at the designed wind speed.

关键词： Wind tunnel simulation Roughness Reynolds number Pressure distribution Solid structure of revolution

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