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New Bradoriid Arthropods from the Early Cambrian Balang Formation of Eastern Guizhou, South China

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Acta Geologica Sinica(English Edition) 2010年第1期84卷 56-68页

作者： PENG Jin FENG Hongzhen fu xiaoping ZHAO Yuanlong YAO Lu College of Earth Science and Engineering Nanjing University Nanjing Jiangsu 210093 China College of Resource and Environment Engineering Guizhou University Guiyang Guizhou 550003 China State Key Laboratory Palaeobiology and Stratigraphy （NIGP CAS） Nanjing Jiangsu 210008 China Paleontological Museum ofShenzhen Xianhu Botanical Garden Shenzhen 5180004 China.

The Early Cambrian Balang Formation is comprised of mudrock and shale, which was deposited in a shelf environment in the eastern part of Guizhou, south China. The Balang Fauna, which consists of seven phyla, occurs in the middle and upper parts of the Balang Formation. Arthropods are important constituents of the Balang Fauna and include a great number of trilobites, large bivalved arthropods, and newly-discovered well-preserved bradoriid fossils. The bradoriids present include three genera and four species ： Comptaluta inflata （Cheng, 1974） emend Hou et al., 2002; Comptaluta kailiensis sp. nov., and Alutella elongeta sp. nov, Aluta sp. This faunal assemblage in the Balang Formation is distinguished from the Tsunyiella Chang, 1964, Songlinella Yin, 1978 and Kunmingella Hou, 1956 assemblage which occurs in the Niutitang and Mingxinsi formations of the Yangtze Platform in middle region of Guizhou and which is earlier than the Balang Formation in age. However, this assemblage resembles the Comptaluta Opik, 1968 assemblage from the Early Cambrian Heilinpu Formation in Wuding County, Yuanan Province and from the Ordian Stage of the Cambrian of Australia. The great abundance of Comptaluta Opik, 1968 and overall taxonomic diversity of the Comptaluta Opik, 1968 assemblage set it distinctly apart from theAlutella Kobayashi et Kato, 1951 and Aluta Hou, 1956 assemblages of the Balang Formation. Alutella Kobayashi et Kato, 1951 and Aluta Hou, 1956 also occur in the Early Cambrian Niutitang Formation of the Yangtze Platform of Guizhou. Individual Bradoriids from the Balang Formation are characterized by large size （〉3 mm）. The discovery of new Bradoriid assemblages not only expands the group＇s geographical range and assemblage affinities, but also indicates that Bradoriids migrated eastward from shallow-water to deeper-water environments during the Early Cambrian, indicating that they were capable of life in deeper-water, and adaptation to a new ecological setting.

关键词： Bradoriids Balang Formation Early Cambrian Guizhou China

Mechanism of action of cordycepin in the treatment of hepatocellular carcinoma via regulation of the Hippo signaling pathway

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Food Science and Human Wellness 2024年第2期13卷 1040-1054页

作者： Xiaomin Li Qing Liu Songyu Xie xiaoping Wu Junsheng fu College of Life Sciences Mycological Research CenterFujian Agriculture and Forestry UniversityFuzhou 350002China

Hepatocellular carcinoma(HCC)is one of the common most malignant *** study aimed to determine the in vitro and in vivo anticancer activity of cordycepin and elucidate its mechanism of *** results of in vitro and in vivo studies revealed that cordycepin inhibited proliferation and migration in HepG-2 cells and inhibited the growth of HepG-2 xenograft-bearing nude mice by inducing *** sequencing analysis revealed a total of 403 differential genes,which revealed that cordycepin may play an anti-HCC role by regulating Hippo signaling *** regulatory effects of cordycepin on the Hippo signaling pathway was further investigated using a YAP1 *** results demonstrated that cordycepin upregulated the expression of MST1 and LAST1,and subsequently inhibited YAP1,which activated the Hippo signaling *** in turn downregulated the expression of GBP3 and ETV5,and subsequently inhibited cell proliferation and ***,YAP1 regulated the expression of Bax and Bcl-2,regulated the mitochondrial apoptotic pathway,and induced apoptosis by upregulating the expression of the caspase-3 *** summary,this study reveals that cordycepin exerts its anti-hepatocarcinoma effect through regulating Hippo signaling pathway,and GBP3 and ETV5 may be potential therapeutic targets for hepatocarcinoma.

关键词： Cordycepin Hepatocellular carcinoma Hippo signaling pathway GBP3 ETV5

A New Arthropod,Guangweicaris Luo,fu et Hu gen. nov. from the Early Cambrian Guanshan Fauna,Kunming,China

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Acta Geologica Sinica(English Edition) 2007年第1期81卷 1-7页

作者： LUO Huilin fu xiaoping HU Shixue LI Yong HOU Shuguang YOU Ting PANG Jiyuan LIU Qi Yunnan Institute of Geological Sciences Kunming Yunnan 650051 Shenzhen Palaeontological Museum Shenzhen Guangdong 518004 Faculty of Earth Science China University of Geosciences Wuhan Hubei 430074

The Guanshan Fauna is a soft-bodied fauna dominated by arthropods （including trilobites, trilobitoides, Tuzoia, Isoxys, and bradorids） in association with priapulids, brachiopods, anomalocaridids, vetulicoliids, sponges, chancellorids, and echinoderms. This paper reports and describes a new arthropod from the yellowish green mudstone at the lower part of the Wulongqing Formation, Canglangpuan Stage, Lower Cambrian in Kunming, Yunnan, China. The stratigraphic and geographic distribution, classification, fossil preservation, life style of this new arthropod and comparisons with other fossil arthropods are also discussed in details. The discovery and research of the non-mineralized arthropod, Guangweicaris Luo, fu et Hu gen. nov. from the Guanshan Fauna adds new members to the taxonomic list and provides new information to the evolution of early arthropods. furthermore, this study would shed new light into the ＂Cambrian Explosion＂ and the evolution of early life.

关键词： Early Cambrian Wulongqing Formation Guanshan Fauna Arthropods Guangwei,Kunming Yunnan

New Record of Palaeoscolecids from the Early Cambrian of Yunnan,China

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Acta Geologica Sinica(English Edition) 2008年第2期82卷 244-248页

作者： HU Shixue LI Yong LUO Huilin fu xiaoping YOU Ting PANG Jiyuan LIU Qi Michael STEINER Yunnan Institute of Geological Sciences Kunming 650051 Yunnan China Shenzhen Palaeontological Museum Shenzhen 518004 Guangdong China State Key Laboratory of Palaeobiology and Stratigraphy （NIGP CAS） Nanjing 210008 China Faculty of Earth Science China University of Geosciences （Wuhan） Wuhan 430074 China Technische Universitdt Berlin D-13355 Berlin Germany

A new palaeoscolecid, Guanduscolex minor Hu, Luo et fu gen. et sp. nov., with preserved soft parts of introvert and intestines comes from the Lower Cambrian Guanshan fauna of Yunnan, South China. Microstructural details of the cuticle revealed by scanning electron microscopy （SEM） show that each annulation bears three rows of plates and each plate bears 9-10 marginal and 4-5 central nodes. This discovery sheds new light on the relationships and evolutionary pathway of the palaeoscolecids and other early priapulids.

关键词： Palaeoscolecid Guanshan fauna ultrastructure Early Cambrian Yunnan China

Fermented Lentinus edodes extract containingα-glucan ameliorates concanavalin A-induced autoimmune hepatitis in mice

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Food Science and Human Wellness 2024年第4期13卷 2102-2115页

作者： Xin Hu Dan Cheng Yingxia Zhang Po Li xiaoping Wu Junsheng fu College of Life Sciences Fujian Agriculture and Forestry UniversityFuzhou 350002China Mycological Research Center Fujian Agriculture and Forestry UniversityFuzhou 350002China Shanghai Lithy One-Health Group Technology Co. Ltd.Shanghai 200235China

Autoimmune hepatitis(AIH)is a chronic inflammatory liver disease that threatens human health *** aim of this study was to detect the protective effect of a fermented Lentinus edodes extract containingα-glucan(FLA),in a concanavalin A(Con A)-induced AIH mouse model and to determine the underlying liver-protective *** results showed that compared with the model group,the level of proinflammatory cytokines in serum of FLA pretreated mice was significantly decreased,and the degree of inflammatory cell infiltration in liver,thymus and spleen was significantly *** polymerase chain reaction,immunohistochemistry,and Western blotting showed that FLA pre-treatment inhibited the Con A-induced apoptosis of hepatocytes by down-regulating the expression of BAX and up-regulating the expression of *** research found that FLA may improve liver injury in mice by activating NRF2 signaling pathway and inhibiting TRAF6/NF-κB signaling ***,FLA may improve liver injury in mice by shifting gut microbial composition to reduce the release of inflammatory cytokines in the serum and prevent the necrosis of ***-regulation of NRF2 signaling pathway,down-regulation of TRAF6/NF-κB signaling pathway,and an increase in the relative abundance of Lactobacillus_johnsonii and Ligilactobacillus_murinus play a protective role in liver.

关键词： Autoimmune hepatitis Concanavalin A Lentinus edodes TRAF6/NF-κB NRF2

A PILLAR OF HUBEI'S POWER INDUSTRY

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China Today 2000年第8期49卷 75-78页

作者： fu xiaoping Jing Yi

Discusses the development of the power industry in Hubei, China. Emphasis on the role of Hubei Provincial Power Development Co. (HPPDC) in the development of the power industry; Statistics on the development of the power industry; How HPPDC started and contributed to the development of power industry in Hubei; Remarks from Xiao Hongjiang, general manager of HPPDC.

关键词： In A PILLAR OF HUBEI’S POWER INDUSTRY

Hubei: Building a Modern Communications Network

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China Today 2000年第10期49卷 22-25页

作者： Chen Zhihong fu xiaoping

Provides an update on the construction of roads and bridges in the Hubei Province, China as of October 2000. Information on the Xiangfan-Jingzhou Expressway; Construction of Changjing Railway; Details on the Yangtze R... 详细信息

关键词： Co Building a Modern Communications Network Hubei

New speices of Late Mesozoic wood fossils from southeastern Mongolia

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Global Geology 2011年第2期14卷 59-66页

作者： DING Qiuhong fu xiaoping LI Yong ZHANG Wu Shengyang Center of Geological Survey China Geological Survy Bureau Shenyang 110034 China Shenzhen Fairy Lake Botanical Garden Shenzhen 518004 Guangdong China

Three new species of fossil woods are reported from the Upper,Jurassic to Lower Cretaceous in southeastern Mongolia, including Protaxodioxylon mongolense sp. nov. Circoporoxylon mongolen.;e sp. nov. Protocircoporoylon... 详细信息

关键词： fossil woods new species Late Mesozoic southeastern Mongolia

农村中职学校内部质量保障建设策略的探索——以河南农村中职为例

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职业技术教育 2018年第17期39卷 9-12页

作者：付小平河南省新安县职业高级中学

基于30所河南农村中职学校的调查数据,参考全面质量管理的"戴明环"模型,把学校内部质量保障建设分为质量目标、质量建设、质量检测、反馈矫正四个部分,并以此作为中职学校内部质量管理的思想基础和方法依据。针对农村中职学校内部质量... 详细信息

基于30所河南农村中职学校的调查数据,参考全面质量管理的"戴明环"模型,把学校内部质量保障建设分为质量目标、质量建设、质量检测、反馈矫正四个部分,并以此作为中职学校内部质量管理的思想基础和方法依据。针对农村中职学校内部质量保障现状与存在问题,提出"准确定位质量目标,全面制定质量标准,重视质量建设过程,改进质量检测手段,提升反馈矫正效能"的农村中职学校内部质量保障建设策略。

关键词：农村中职学校教育质量内部质量质量保障