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The Mediating Effect of Body Dissatisfaction in Association between Obesity and Dietary Behavior Changes for Weight Loss in Chinese Children

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Biomedical and Environmental Sciences 2019年第9期32卷 639-646页

作者： GAO Huai Quan WANG Bang Xuan SUN Li Li LI Ting WU Lu fu lian guo MA Jun Department of Child and Adolescent Health School of Public HealthBengbu Medical CollegeBengbu 233030AnhuiChina Institute of Child and Adolescent Health School of Public HealthPeking University Health Science CenterBeijing 100191China

Objective The aim of this study was to analyze the mediating effect of body dissatisfaction in correlation between obesity and dietary behavior changes for weight loss(DBCWL).Methods A total of 680 primary and middle school students were included in this study. Their body height, weight, and waistline were effectively measured, and they were also evaluated to assess their body dissatisfaction, perception of dietary behaviors, and DBCWL. The correlation among these factors was analyzed using mediating effect *** The prevalence of overweight/obesity and abdominal obesity was significantly higher in males than in females(P < 0.05). Overweight/obesity, abdominal obesity, and body dissatisfaction significantly increased the risk for DBCWL(OR = 2.57, 2.77, and 1.95, respectively). Overweight/obesity and abdominal obesity significantly increased the risk for body dissatisfaction(OR = 6.00 and 4.70,respectively). Significant mediating effects of body dissatisfaction were observed in correlation between overweight/obesity and DBCWL and between abdominal obesity and DBCWL(OR = 2.20 and 1.92,respectively;P < 0.05), and the proportions of mediating effects among the total effects were 48.89% and 46.60%, *** Body dissatisfaction might play an important mediating effect in association between DBCWL and obesity, which indicates that guiding children to correctly recognize their body might be more conducive than promoting obese children toward weight loss through dietary behavior changes.

关键词： Children and adolescents Obesity Body dissatisfaction Dietary behavior changes for weight loss

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Research and Practice of Production Technology for High Performance Low Alloy Steels in WISCO

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Journal of Iron and Steel Research International 2011年第S1期18卷 99-103页

作者： fu lian-chun,guo Ai-ming,LIU Ji-bin,guo Bin,CHEN Yan-tang [Wuhan Iron and Steel (Group) Corporation,Wuhan 430080,Hubei,China] Wuhan Iron & Steel Grp Corp Wuhan 430080 Hubei Peoples R China

The product system of high strength low alloy steels (HSLA) produced by Wuhan Iron and Steel (Group) Corporation (WISCO) was presented.A series of high performance structural steels have been developed for important construction projects around the world in different areas,such as bridge,pressure vessel,pipe line,shipbuilding,architecture,machinery and railway *** order to promote the development of large heat input welding steel,high grade thick pipeline steel and long span bridge steel,a lot of advanced production technologies have been achieved through intensive investigation,such as the control of high purity,high homogenization and free defects in steel slabs,the rules of high melting point particle formation and distribution in micro and nano scale during steel production,and the TMCP technology for ultra low carbon bainite steel for medium and heavy *** will carry on research and application of economic and weather-resistant steels and promote the developing and producing technologies of HSLA steel.

关键词： WISCO high performance low alloy steels production technology

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The Influence of Secular Trends in Body Height and Weight on the Prevalence of Overweight and Obesity among Chinese Children and Adolescents

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Biomedical and Environmental Sciences 2016年第12期29卷 849-857页

作者： fu lian guo SUN Li Li WU Shao Wei YANG Yi De LI Xiao Hui WANG Zheng He WU Lu WANG fu Zhi MA Jun Department of Preventive Medicine Bengbu Medical College Department of Environmental Health Harvard T.H.Chan School of Public Health Institute of Child and Adolescent Health School of Public HealthPeking University Health Science Center

Objective To explore the influence of secular trends in body height and weight on the prevalence of overweight and obesity among Chinese children and adolescents. Methods The data were obtained from five cross-sectional Chinese National Surveys on Students＇ Constitution and Health. Overweight/obesity was defined as BMI-for-age Z-score of per the Wold Health Organization （WHO） reference values. Body height and weight for each sex and age were standardized to those reported in 1985 （standardized height＂ SHY, standardized weight： SWY） and for each sex and year at age 7 （standardized height： SHA; standardized weight： SWA） using the Z-score method. Results The prevalence of overweight/obesity in Chinese children was 20.2% among boys and 10.7% among girls in 2010 and increased continuously from 1985 to 2010. Among boys and girls of normal weight, SHY and SHA were significantly greater than SWY and SWA, respectively （P 〈 0.001）. Among boys and girls with overweight/obesity, SHY was significantly lower than SWY （P 〈 0.001）, and showed an obvious decreasing trend after age 12. SHA was lower than SWA among overweight boys aged 7-8 years and girls aged 7-9 years. SHY/SHW and SHA/SWA among normal-weight groups were greater than among overweight and obese groups （P 〈 0.001）. Conclusion The continuous increase in the prevalence of overweight/obesity among Chinese children may be related to a rapid increase in body weight before age 9 and lack of secular increase in body height after age 12.

关键词： Obesity Children Secular trends Body height Body weight

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An Objective Measure to Evaluate Actual Body Shape among Children and Adolescents in China

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Biomedical and Environmental Sciences 2014年第8期27卷 582-593页

作者： fu lian guo WANG Hai Jun LI Xiao Hui WANG Zhi Qiang Patrick WC Lau YANG Yi De MENG Xiang Kun MA Jun Institute of Child and Adolescent Health School of Public Health Peking University Health Science Center Centre for Chronic Disease School of Medicine University of Queensland Department of Physical Education Hong Kong Baptist University

Objective The purpose of this study was to explore an objective measure to assess actual body shape of children and adolescents in China. Methods Based on the Chinese National Survey on Student＇s Constitution and Health （CNSSCH） in 2005, 210 927 children and adolescents＇（7-18 years） body height, body weight, chest circumference, sitting height, chest circumference-height ratio, chest circumference-sitting height ratio, chest circumference-low limb ratio, and sitting height-low limb ratio measurements were used to develop an objective measure by using transformation variables and explored factor analysis （EFA）. Discrimination power of the objective measure was evaluated based on BMI reference and Receiver Operating Characteristic curves （ROC）. Results The objective measure included four dimensions scores：transverse dimension （TD） indicating weight and chest circumference; length dimension （LD） indicating height and sitting height;transverse-length ratio dimension （TLD） indicating chest circumference-height ratio, chest circumference-sitting height and chest circumference-low limb ratio; proportion dimension （PD） indicating sitting height-low limb ratio. The whole dimension （WD） indicating the whole body shape was showed by the average of four dimensions scores. Four dimensions and WD scores were approximately 80 in children and adolescents with normal weight, and higher than those of overweight, obesity, and underweight （all P-values〈0.001）. Areas under ROC of overweight and obesity compared with normal weight ranged from 0.88 to 1.00 for scores of TD, TLD, and WD. Conclusion The objective measure which included four dimensions was explored, and TD, TLD, and WD had significant discrimination power.

关键词： Objective measure Body shape Children and adolescents

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Reducing the measurement errors in nonadiabatic holonomic quantum computers

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 64-70页

作者： guo-fu Xu Department of Physics Shandong University

Nonadiabatic holonomic quantum computers serve as the physical platform for nonadiabatic holonomic quantum *** quantum computation has entered the noisy intermediate-scale era, building accurate intermediate-scale nonadiabatic holonomic quantum computers is clearly necessary. Given that measurements are the sole means of extracting information, they play an indispensable role in nonadiabatic holonomic quantum computers. Accordingly, developing methods to reduce measurement errors in nonadiabatic holonomic quantum computers is of great importance. However, while much attention has been given to the research on nonadiabatic holonomic gates, the research on reducing measurement errors in nonadiabatic holonomic quantum computers is severely lacking. In this study, we propose a measurement error reduction method tailored for intermediate-scale nonadiabatic holonomic quantum computers. The reason we say this is because our method can not only reduce the measurement errors in the computer but also be useful in mitigating errors originating from nonadiabatic holonomic gates. Given these features,our method significantly advances the construction of accurate intermediate-scale nonadiabatic holonomic quantum computers.

关键词： quantum holonomy quantum computation measurement errors

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中国11～15岁青春期男生遗精发生与身体形态发育的关系

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中华预防医学杂志 2013年第8期47卷 695-699页

作者：孟祥睿王海俊付连国董彬马军北京大学公共卫生学院北京大学儿童青少年卫生研究所 100191

目的调查中国11～15岁青春期男生遗精与身体形态发育的关系。方法从2010年全国学生体质与健康调查数据中选取11—15岁男生的身高、体重、胸围、腰围、臀围等体测项目和遗精情况等资料，并计算BMI和腰围身高比。按同年龄（相差±0．1岁）... 详细信息

目的调查中国11～15岁青春期男生遗精与身体形态发育的关系。方法从2010年全国学生体质与健康调查数据中选取11—15岁男生的身高、体重、胸围、腰围、臀围等体测项目和遗精情况等资料，并计算BMI和腰围身高比。按同年龄（相差±0．1岁）l：1随机匹配已遗精和未遗精男生，最终获得已遗精男生和未遗精男生各3440名，共计6880名。采用t检验分析不同年龄组中两组男生各项指标的差异；使用多水平模型分析遗精与身体形态发育的关系。结果在6880名调查对象中，11—15岁各组已遗精男生的身高分别为（150．96±8．叭）、（159．46±8．03）、（163．76±7．43）、（167．03±7．12）、（169．50±6．64）em，未遗精男生分别为（147．38±6．54）、（153．55±8．68）、（160．35±8．66）、（164．44±7．98）、（167．98±7．80）cm，差异有统计学意义（t值分别为3．70、9．96、10．76、8．26、3．21，P值均〈0．01）。多水平模型分析结果显示，11～13岁各组体重的差异最大，遗精组男生比非遗精组分别高4．20、7．23、3．93kg（Wald。值分别为13．11、70．73、72．93，P值均〈0．01）；14～15岁各组身高的差异最大，遗精组男生比非遗精组分别高2．81、1．99em（WaldX。值分别为87．80、19．54，P值均〈0．01）；遗精与未遗精男生各项指标的差异（p值）均随年龄呈抛物线变化，12岁组男生体重、BMI、身高、胸围、腰围、臀围、腰围身高比差异最大，8值分别为7．23kg、1．64kg／m2、5．55cm、4．40cm、4．63cm、4．94CITI、0．015；15岁组各项指标差异最小，B值分别为-0．39kg、-0．56kg／m2、1．99cm、-0．57cm、-1．59cm、-0．42cm、-0．015。结论中国11～15岁男生遗精发生与身体形态发育存在相关性，且随年龄呈抛物线变化趋势。

关键词：青春期模型,统计学青春期发育遗精身体形态多水平分析

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Regulation of graphdiyne-based nanozymes with enhanced oxidaselike activity by cobalt and nitrogen codoping

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Nano Research 2025年第1期18卷 21-29页

作者： Jiali Liu Xiaoli Wang Yongfu lian Xue Wang Xiuxiu Wang Xingfa Gao Baoyun Sun Xihong guo CAS Key Laboratory for Biomedical Effects of Nanomaterial&Nanosafety Institute of High Energy PhysicsChinese Academy of ScienceBeijing 100049China Key Laboratory of functional Inorganic Material Chemistry Ministry of EducationSchool of Chemistry and Materials ScienceHeilongjiang UniversityHarbin 150080China Laboratory of Theoretical and Computational Nanoscience National Center for Nanoscience and TechnologyBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China

The development of nanozymes with excellent intrinsic oxidase-like activity and specificity has received increasing ***(GDY)could be a promising choice for designing nanozymes with enhanced oxidase(OXD)-like activity due to its unique structure and ***,Co-N-GDY with high OXD activity but no peroxidase(POD)activity was synthesized by codoping of cobalt(Co)and nitrogen(N)into GDY and compared with other GDY-based nanozymes(including GDY,Co-GDY,and N-GDY).Upon analyzing the doping effect of Co and N on the OXD-like and POD-like activities,we found that the combination of Co and N in GDY played a significant role in enhancing the OXD-like activity,and even reversed the POD-like activity of N-GDY to OXD-like activity of *** electrochemical experiment and the theoretical calculations provided an explanation for the mechanism and showed that the activity was closely linked to the reduction ability of O_(2) or H_(2)O_(2) on the nanozyme substrates,which was determined by the ratedetermining step of the catalytic reaction.

关键词： nanozymes oxidase-like activity graphdiyne heteroatom doping regulation

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2010年中国7～18岁汉族学生超重、肥胖与生理功能的关系

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中华预防医学杂志 2012年第9期46卷 796-801页

作者：王海俊付连国马军宋逸胡佩瑾张冰北京大学公共卫生学院北京大学儿童青少年卫生研究所 100191

目的研究儿童青少年超重、肥胖状况与生理功能（收缩压、舒张压、脉搏、体重肺活量指数）之间的关系。方法利用2010年中国学生体质与健康调研资料，按性别、城乡分层频数匹配，以肥胖分组等比抽取7～18岁体重正常、超重、肥胖组学生各10... 详细信息

目的研究儿童青少年超重、肥胖状况与生理功能（收缩压、舒张压、脉搏、体重肺活量指数）之间的关系。方法利用2010年中国学生体质与健康调研资料，按性别、城乡分层频数匹配，以肥胖分组等比抽取7～18岁体重正常、超重、肥胖组学生各10601名。比较3组学生的生理功能水平，并分析生理功能水平随BMI百分位数的变化情况。结果与体重正常者相比，各年龄段肥胖男生收缩压增加8．0～12．0mmHg（1mmHg=0．133kPa），舒张压增加4．7—5．9mmHg，肥胖女生收缩压增加7．5～11．6mmHg，舒张压增加4．7—6．1mmHg，差异均有统计学意义（P值均〈0．05）。13～15岁肥胖男生脉搏比体重正常者增加0．8次／min，16～18岁肥胖男生脉搏分别比超重和体重正常者增加1．1次／min，16～18岁肥胖女生脉搏分别比超重和体重正常者增加1．5、1．7次／min（P值均〈0．05）。7～9岁男生BMI为第5、50、95百分位数（P5、P50、P95）时脉搏分别为87．63、87．00、87．83次／min，10～12岁男生分别为85．66、85．30、85．43次／min。13—15岁男生BMI为P5、P50、P95时脉搏分别为82．60、81．39、82．34次／min，16—18岁男生分别为80．15、79．00、79．980次／min。各年龄段男、女生的体重肺活量指数均表现为肥胖组〈超重组〈体重正常组（P〈0．05），与体重正常者相比，超重男生减少6．4～8．4ml／kg，肥胖男生减少11．9—14．8ml／kg，超重女生减少5．3～7．7ml／kg，肥胖女生减少11．0～11．5ml／kg。结论超重、肥胖的儿童青少年较体重正常者血压升高、脉搏增加、体重肺活量指数下降。

关键词：营养过剩生理学儿童青少年

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中国7～17岁青春期女生月经初潮较早与血压水平的关系

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中华预防医学杂志 2013年第8期47卷 726-730页

作者：邹志勇马军王海俊付连国董彬阳益德北京大学公共卫生学院北京大学儿童青少年卫生研究所 100191

目的分析中国7～17岁女生青春期月经初潮较早与血压水平的关系。方法从2010年全国学生体质与健康调研资料中，选择体测项目（身高、体重、血压等）、月经初潮史等资料记录完整的7～17岁女生作为研究对象，共76869名。采用概率单位回归... 详细信息

目的分析中国7～17岁女生青春期月经初潮较早与血压水平的关系。方法从2010年全国学生体质与健康调研资料中，选择体测项目（身高、体重、血压等）、月经初潮史等资料记录完整的7～17岁女生作为研究对象，共76869名。采用概率单位回归法计算女生月经初潮年龄的第10百分位数（P）概率界值，月经初潮出现年龄小于其对应的界值定义为初潮时间较早，按城乡、年龄进行1：2匹配未来初潮者，初潮较早者和未来潮者分别作为初潮较早组和未来潮组，收缩压或舒张压大于其对应的同年龄第95百分位数（P）值定义为“收缩压或舒张压偏高”，收缩压和（或）舒张压大于其对应的同年龄B，值定义为“血压偏高”。采用X2检验分析已来潮和未来潮女生血压偏高检出率的差异，并用多水平模型分析初潮较早与血压水平的关系。结果76869名女生身高为（152．2±10．4）cm，BMI为（18．7±3．1）kg／m2，收缩压和舒张压值分别为（103．4±11．0）mmHg（1mmHg=0．133kPa）和（65．0±9．1）mmHg，已来潮女生有47942名（62．4％），未来潮女生有28927名（37．6％）。女生9岁开始出现月经初潮，13岁时有81．5％（7123／8736）的女生已出现月经来潮。11岁组、12岁组、13岁组已来潮女生血压偏高的检出率分别为6．71％（100／1490）、5．99％（265／4423）、5．38％（383／7123），明显高于同龄未来潮女生的3．78％（265／7005）、3．33％（144／4328）、4．09％（66／1613），差异有统计学意义（x。值分别为25．62、32．36、4．46，P值均〈0．05）。初潮较早者年龄在9—11岁，其中11岁组血压偏高、收缩压偏高、舒张压偏高的检出率分别为6．08％（49／806）、4．84％（39／806）、3．35％（27／806），明显高于同年龄未来潮组的3．11％（50／1607）、2．30％（37／1607）、1．43％（23／1607），差异有统计学意义（）（2值分别为12．02、11．32、9．74，P值均〈0．01）。多水平模型分析显示，在控制了不同省（自治区、直辖市）和年龄后，初潮较早者血压偏高的检出率仍然高于同龄未来潮者[OR=2．188（95％CI：1．254—3．818）]，其中初潮较早者收缩压和舒张压偏高的检出率均高于同龄未来潮者[OR（95％CI）值分别为1．925（1．097～3．379）、2．088（1．072～4．065）]。结论月经初潮较早可能与血压升高有关联，可能会导致我国儿童青少年血压升高的年龄进一步提前。

关键词：青春期月经初潮血压模型,统计学

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扶正抑瘤颗粒对小鼠肝癌H22细胞凋亡率及线粒体膜电位的影响

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中西医结合学报 2006年第3期4卷 271-274页

作者：赵健雄郭芙莲白德成王学习兰州大学中西医结合研究所甘肃兰州730000

目的:观察扶正抑瘤颗粒对小鼠肝癌H22细胞凋亡率及线粒体膜电位的影响。方法:48只荷瘤小鼠随机分为模型组、环磷酰胺治疗组、扶正抑瘤颗粒大剂量治疗组和扶正抑瘤颗粒小剂量治疗组,分别予以相应药物治疗14 d。碘化丙啶染色,流式细胞术... 详细信息

目的:观察扶正抑瘤颗粒对小鼠肝癌H22细胞凋亡率及线粒体膜电位的影响。方法:48只荷瘤小鼠随机分为模型组、环磷酰胺治疗组、扶正抑瘤颗粒大剂量治疗组和扶正抑瘤颗粒小剂量治疗组,分别予以相应药物治疗14 d。碘化丙啶染色,流式细胞术检测各组小鼠肝癌H22细胞的凋亡率。采用荧光探针罗丹明123负载,激光扫描共聚焦显微镜下观察H22细胞的荧光强度,分析H22细胞线粒体膜电位的大小。结果:扶正抑瘤颗粒可以提高小鼠肝癌H22细胞的凋亡率,降低H22细胞的线粒体膜电位,与模型组比较,差异有统计学意义。结论:扶正抑瘤颗粒的抗肿瘤机制可能与降低肿瘤细胞线粒体膜电位,诱导肿瘤细胞凋亡有关。

关键词：扶正抑瘤颗粒癌,肝细胞细胞凋亡线粒体膜电位

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