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Effects of chitooligosaccharide-zinc on the ovarian function of mice with premature ovarian failure via the SESN2/NRF2 signaling pathway

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Chinese Journal of Natural Medicines 2021年第10期19卷 721-731页

作者： LI jia CHEN Yu-Hang XU jia-Yu LIU jiang-Ying fu jia-cheng CAO Xiu-Ping HUANG jian ZHENG Yue-Hui Medical Experimental Teaching Center Nanchang UniversityNanchang 330006China The Second Clinical Medical College Nanchang UniversityNanchang 330006China The First Clinical Medical College Nanchang UniversityNanchang 330006China School of Basic Medicine Nanchang UniversityNanchang 330006China Shenzhen Traditional Chinese Medicine Hospital Shenzhen 518000China Key Laboratory of Reproductive Physiology and Pathology of jiangxi Province Nanchang UniversityNanchang 330006China

Chitooligosaccharide-zinc(COS·Zn)is a powerful anti-oxidant and anti-aging scavenger,whose anti-oxidative ability immensely exceeds vitamin ***,this study was aimed to investigate the protective effects of COS·Zn against premature ovarian failure(POF)and potential *** KM adult mice were divided into the following groups:a treatment group(150 mg·kg^(−1)·d^(−1) COS·Zn),a treatment group(300 mg·kg^(−1)·d^(−1) COS·Zn),a prevention group,two control groups and two CY/BUS ***·Zn(150,300 mg·kg^(−1)·d^(−1))and COS·Zn(300 mg·kg^(−1)·d^(−1))were therapeutically and preventatively administered to POF mice in the treatment and prevention studies,*** the groups were administered for 21 *** primary and secondary follicles were observed in the COS·Zn-treated groups(including the treatment and prevention groups)than those of the control ***,the ovarian index and the levels of FSH and LH notably increased in the treatment and prevention groups compared with those in the CY/BUS *** levels of MVH,OCT4 and PCNA in the treatment group(300·kg^(−1)·d^(−1) COS·Zn)and MVH in the prevention group remarkably increased compared with those in the CY/BUS ***,the levels of P53 and P16 protein were down-regulated in the treatment and prevention groups compared with those in the CY/BUS ***,the amounts of Sestrin2(SESN2)and SOD2 protein were obviously higher in the treatment group(150 mg·kg^(−1)·d^(−1) COS·Zn)than those in the CY/BUS ***,the amounts of NRF2 and SESN2 protein were up-regulated in the prevention ***,an increased GSH level was observed in the two treatment groups,compared with that in the CY/BUS groups,and the same trend was also present in the prevention *** together,COS·Zn improves the ovarian and follicular development through regulating the SESN2/NRF2 signaling *** results suggest the role of COS·Zn as a novel agent for the treatment and preventi

关键词： Premature ovarian failure Chitooligosaccharide-zinc Sestrin2-nrf2 Ovarian function Aging

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侧链式含硅氧烷高分子的聚合度对晶体结构的影响

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高分子通报 2024年第9期37卷 1254-1262页

作者：贾富成尤恒之洪程阳刘浩东华大学纤维材料改性国家重点实验室先进低维材料中心上海201620

高分子结晶行为与其材料性能密切相关,是高分子物理学一个重要的基础研究领域。含团簇高分子是近年来兴起的一类新型杂化高分子,它结合了纳米团簇类物质丰富的功能性与高分子材料良好的可加工性,为先进杂化材料的开发提供了新的思路。... 详细信息

高分子结晶行为与其材料性能密切相关,是高分子物理学一个重要的基础研究领域。含团簇高分子是近年来兴起的一类新型杂化高分子,它结合了纳米团簇类物质丰富的功能性与高分子材料良好的可加工性,为先进杂化材料的开发提供了新的思路。本文以侧链式含多面体倍半硅氧烷(POSS)团簇高分子为研究对象,通过精准化学技术控制其分子参数,合成了一系列具有不同聚合度的精准高分子。通过在溶液中进行单晶生长,并对其形貌、结构与热力学参数进行系统分析,发现本文研究范围内的聚合度并不影响单晶的晶体结构,也与片晶厚度、熔融温度等无明显关联性。从溶液中生长的单晶受到溶剂、温度、浓度扰动等动力学因素的影响较大,并非热力学稳定态晶体。

关键词：含团簇高分子高分子单晶多面体倍半硅氧烷精准合成

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Advancements and Challenges in Organic–Inorganic Composite Solid Electrolytes for All‑Solid‑State Lithium Batteries

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Nano-Micro Letters 2025年第1期17卷 46-97页

作者： Xueyan Zhang Shichao cheng Chuankai fu Geping Yin Liguang Wang Yongmin Wu Hua Huo State Key Laboratory of Space Power‑Sources School of Chemistry and Chemical EngineeringHarbin Institute of TechnologyHarbin 150001People’s Republic of China College of Chemical and Biological Engineering Zhejiang UniversityHangzhou 310058People’s Republic of China State Key Laboratory of Space Power-Sources 2965 Dongchuan RoadMinhang DistrictShanghai 200240People’s Republic of China

To address the limitations of contemporary lithium-ion batteries,particularly their low energy density and safety concerns,all-solid-state lithium batteries equipped with solid-state electrolytes have been identified as an up-and-coming *** the various SEs,organic–inorganic composite solid electrolytes(OICSEs)that combine the advantages of both polymer and inorganic materials demonstrate promising potential for large-scale ***,OICSEs still face many challenges in practical applications,such as low ionic conductivity and poor interfacial stability,which severely limit their *** review provides a comprehensive overview of recent research advancements in ***,the influence of inorganic fillers on the main functional parameters of OICSEs,including ionic conductivity,Li+transfer number,mechanical strength,electrochemical stability,electronic conductivity,and thermal stability are systematically *** lithium-ion conduction mechanism of OICSE is thoroughly analyzed and concluded from the microscopic ***,the classic inorganic filler types,including both inert and active fillers,are categorized with special emphasis on the relationship between inorganic filler structure design and the electrochemical performance of ***,the advanced characterization techniques relevant to OICSEs are summarized,and the challenges and perspectives on the future development of OICSEs are also highlighted for constructing superior ASSLBs.

关键词： Composite solid electrolytes Inorganic filler Interfacial stability Li-ion conduction mechanism Characterization techniques

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Gradient‑Layered MXene/Hollow Lignin Nanospheres Architecture Design for Flexible and Stretchable Supercapacitors

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Nano-Micro Letters 2025年第2期17卷 447-462页

作者： Haonan Zhang cheng Hao Tongtong fu Dian Yu Jane Howe Kaiwen Chen Ning Yan Hao Ren Huamin Zhai jiangsu Provincial Key Lab of Sustainable Pulp and Paper Technology and Biomass Materials NanJing Forestry UniversityNanjing 210037People’s Republic of China Department of Chemical Engineering and Applied Chemistry University of Toronto200 College StreetTorontoON M5S 3E5Canada Department of Materials Science and Engineering University of Toronto184 College StreetTorontoON M5S 3E4Canada College of Materials Science and Engineering Nanjing Forestry UniversityNanjing 210037People’s Republic of China

With the rapid development of flexible wearable electronics,the demand for stretchable energy storage devices has *** this work,a novel gradient-layered architecture was design based on single-pore hollow lignin nanospheres(HLNPs)-intercalated two-dimensional transition metal carbide(Ti_(3)C_(2)T_(x) MXene)for fabricating highly stretchable and durable *** depositing and inserting HLNPs in the MXene layers with a bottom-up decreasing gradient,a multilayered porous MXene structure with smooth ion channels was constructed by reducing the overstacking of MXene ***,the micro-chamber architecture of thin-walled lignin nanospheres effectively extended the contact area between lignin and MXene to improve ion and electron accessibility,thus better utilizing the pseudocapacitive property of *** these strategies effectively enhanced the capacitive performance of the *** addition,HLNPs,which acted as a protective phase for MXene layer,enhanced mechanical properties of the wrinkled stretchable electrodes by releasing stress through slip and deformation during the stretch-release cycling and greatly improved the structural integrity and capacitive stability of the *** electrodes and symmetric flexible all-solid-state supercapacitors capable of enduring 600%uniaxial tensile strain were developed with high specific capacitances of 1273 mF cm^(−2)(241 F g^(−1))and 514 mF cm^(−2)(95 F g^(−1)),***,their capacitances were well preserved after 1000 times of 600%stretch-release *** study showcased new possibilities of incorporating biobased lignin nanospheres in energy storage devices to fabricate stretchable devices leveraging synergies among various two-dimensional nanomaterials.

关键词： Hollow lignin nanospheres MXene Gradient-layered architecture Wrinkled electrodes Stretchable supercapacitors

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苹果梨果汁澄清工艺研究

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保鲜与加工 2017年第6期17卷 47-50,55页

作者：王立正贾福晨李梁刘振东薛蓓西藏农牧学院食品科学学院西藏林芝860000

以透光率为考察指标,采用超声波协同壳聚糖、活性炭澄清处理苹果梨果汁,在单因素试验的基础上,通过正交试验筛选苹果梨果汁最佳澄清工艺。结果表明,苹果梨果汁澄清最佳工艺为:壳聚糖添加量0.3%,活性炭添加量4%,超声功率600 W,处理温度35... 详细信息

以透光率为考察指标,采用超声波协同壳聚糖、活性炭澄清处理苹果梨果汁,在单因素试验的基础上,通过正交试验筛选苹果梨果汁最佳澄清工艺。结果表明,苹果梨果汁澄清最佳工艺为:壳聚糖添加量0.3%,活性炭添加量4%,超声功率600 W,处理温度35℃,超声时间40 min,在此条件下,苹果梨果汁澄清效果最佳,透光率可达93%。

关键词：超声波壳聚糖活性炭苹果梨果汁澄清

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从近两届大学生物理竞赛再看工科物理实验教学

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物理实验 2004年第2期24卷 30-32页

作者：张昌芳刘家福季诚响装甲兵工程学院基础部北京100072

通过对近两届工科大学生物理竞赛成绩较好的 5所重点院校的理论得分和实验得分进行对比 ,分析了实验得分率明显偏低的原因 ,并对工科院校的大学物理实验教学提出新思考 .

关键词：大学教育物理实验物理竞赛教学改革实验素质数据处理实验设计

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Reducing the measurement errors in nonadiabatic holonomic quantum computers

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 64-70页

作者： Guo-fu Xu Department of Physics Shandong University

Nonadiabatic holonomic quantum computers serve as the physical platform for nonadiabatic holonomic quantum *** quantum computation has entered the noisy intermediate-scale era, building accurate intermediate-scale nonadiabatic holonomic quantum computers is clearly necessary. Given that measurements are the sole means of extracting information, they play an indispensable role in nonadiabatic holonomic quantum computers. Accordingly, developing methods to reduce measurement errors in nonadiabatic holonomic quantum computers is of great importance. However, while much attention has been given to the research on nonadiabatic holonomic gates, the research on reducing measurement errors in nonadiabatic holonomic quantum computers is severely lacking. In this study, we propose a measurement error reduction method tailored for intermediate-scale nonadiabatic holonomic quantum computers. The reason we say this is because our method can not only reduce the measurement errors in the computer but also be useful in mitigating errors originating from nonadiabatic holonomic gates. Given these features,our method significantly advances the construction of accurate intermediate-scale nonadiabatic holonomic quantum computers.

关键词： quantum holonomy quantum computation measurement errors

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时间规划问题中R_-时刻表及其应用

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微机发展 2004年第12期14卷 139-141页

作者：钱付兰程家兴阚涛余澄丹安徽大学计算智能与信号处理教育部重点实验室安徽合肥230039

为了处理实际生活中出现的对有时间先后关系约束的事件进行排序的问题,诸如学校排课问题、运动会会场安排问题等一系列资源分配问题,文中实现了一种解决该问题的算法。该算法以文献[1]中的关系矩阵的方法为基础,构造以时间关系约束为条... 详细信息

为了处理实际生活中出现的对有时间先后关系约束的事件进行排序的问题,诸如学校排课问题、运动会会场安排问题等一系列资源分配问题,文中实现了一种解决该问题的算法。该算法以文献[1]中的关系矩阵的方法为基础,构造以时间关系约束为条件的时刻表———R-时刻表的一种算法。利用该算法对运动会会场项目进行安排,结果表明在仅为时间关系约束的前提下取得了较好的效果,从而实现了对该类问题的一种新的解决方法。

关键词：时间规划 R_时刻表时刻表关系矩阵

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Research on the operating characteristics of parallel 4-DOF electric platform with 4TPS-PS structure

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2007年第11期8卷 1800-1807页

作者： cheng jia WANG Xuan-yin fu Xiao-jie LI Qiang The State Key Laboratory of Fluid Power Transmission and Control Zhejiang University Hangzhou 310027 China

The 4TPS-PS parallel platform designed for a stabilization and automatic tracking system is a novel lower-mobility parallel mechanism. In the first part of this paper, the structure of the platform is described and the kinematics model is built. The workspace of the platform is defined as the full reachable rotation workspace when the Z coordinate dimension of the upper plate varies continuously. A fast searching method of the full reachable workspace is presented, after which the inverse kinematics of the platform is deduced. The forward and inverse solutions of the speed and force of the platform are deduced. According to the characteristic of the 4TPS-PS platform’s structure, a fast searching algorithm of the maximum generalized speed and maximum generalized force output by the upper plate is put forward based on the forward and inverse solutions of the platform’s speed and force. The 4TPS-PS platform prototype built by the State Key Laboratory of Fluid Power Transmission and Control of China is taken as the research subject. The full reachable rotation workspace of the prototype is computed out and analyzed. The curves of maximum generalized speed and maximum generalized force of the prototype are computed out and plotted. Finally, the com- puting and analyzing results of the operating characteristics are confirmed through the experiment.

关键词： Parallel mechanism 4-DOF Workspace Generalized speed Generalized force

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A phenomenological model for plastic flow behavior of rotating band material with a large temperature range

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Defence Technology（防务技术） 2023年第7期25卷 121-133页

作者： Yi-cheng Zhu jia-wei fu Lin-fang Qian Jing-hua Cao School of Mechanical Engineering Nanjing University of Science and TechnologyNanjing210094JiangsuChina Northwest Institute of Mechanical and Electrical Engineering Xianyang712099ShaanxiChina School of Materials Science and Engineering Nanjing University of Science and TechnologyNanjing210094China

The plastic flow behavior of the rotating band material is investigated in this paper. The rotating band material is processed from H96 brass alloy, which is hardened to a much higher yield strength compared to the annealed one. The dynamically uniaxial compression behavior of the material is tested using the split Hopkinson pressure bar(SHPB) with temperature and strain rate ranging from 297 to 1073 K and500 to 3000 s^(-1), respectively, and a phenomenological plastic flow stress model is developed to describe the mechanical behavior of the material. The material is found to present noticeable temperature sensitivity and weak strain-rate sensitivity. The construction of the plastic flow stress model has two steps. Firstly, three univariate stress functions, taking plastic strain, plastic strain rate and temperature as independent variable, respectively, are proposed by fixing the other two variables. Then, as the three univariate functions describe the special cases of flow stress behavior under various conditions, the principle of stress compatibility is adopted to obtain the complete flow stress function. The numerical results show that the proposed plastic flow stress model is more suitable for the rotating band material than the existing well-known models.

关键词： Rotating band Plastic flow behavior Large temperature range Phenomenological model

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