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Efficacy of Huoxue Qianyang Qutan Recipe on essential hypertension:A randomized,double-blind,placebo-controlled trial

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Journal of Integrative Medicine 2024年第4期22卷 484-492页

作者： Jun Xie Yu-long Ma Ming-tai Gui Lei Yao Jian-hua Li Ming-zhu Wang Xun-jie Zhou Yi-fan Wang Ming-yi Zhao Hui Cao Bo Lu de-yu fu department of Cardiology Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghai 200437China Shanghai University of Traditional Chinese Medicine Shanghai 200120China

Background:Hypertension,a prevalent disease,is a significant risk factor for coronary heart *** Qianyang Qutan Recipe (HQQR),a traditional Chinese herbal remedy,has been used for treating hypertension over several ***:This study assesses HQQR’s efficacy for controlling blood pressure among patients with hypertension related to blood stasis,yang hyperactivity and ***,setting,participants and interventions:A randomized controlled trial was conducted at the Yueyang Hospital of Integrated Traditional Chinese and Western Medicine,Shanghai University of Traditional Chinese Medicine,China,from July 2020 to June *** components of HQQR were identified using thin-layer chromatography and high-performance liquid *** aged18–80 years,exhibiting traditional Chinese medicine syndromes of blood stasis,yang hyperactivity or phlegm,along with grades 1 or 2 hypertension,were randomly categorized into two *** intervention group was given HQQR granules alongside conventional hypertension treatment,while the control group was given placebo granules in addition to conventional treatment for 12 *** outcome measures:The primary outcome was clinic blood pressure,whereas secondary outcomes included metabolic indices (e.g.,homeostasis model assessment of insulin resistance[HOMA-IR],total cholesterol[TC],low-density lipoprotein cholesterol and triglyceride),target organ damage indices (left ventricular mass index and urinary albumin creatinine ratio[UACR]) and inflammation indices(interleukin-6[IL-6]and high-sensitivity C-reactive protein[hs-CRP]).Results:HQQR’s primary components were identified as salvianolic acid B,emodin and ferulic *** the 216 participants (108 in each group),compared to the control,the intervention group exhibited significant improvements (P<0.001) in clinic systolic blood pressure ([136.24±7.63]vs[130.06±8.50]mmHg),clinic diastolic blood pressure ([84.34±8.72]vs[80.46±6.05]mmHg),home systol

关键词： Huoxue Qianyang Qutan Recipe Hypertension Target organ damage Glycolipid metabolism Inflammatory Chinese herbal compound

Advancing the predictive accuracy of PNTML in rectal prolapse:An ongoing quest

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World Journal of Clinical Cases 2024年第29期12卷 6266-6270页

作者： Jin Meng zhi-Gang Wang Li-Mei Zhang de-Yu Chen Ying Wang Hai-Xia Bai Cheng-Chun Ji de-Long Liu Xiao-Fei Zhao Yuan Liu Bo-Yang Li Lei Wang Tian-fu Wang Wei-Gang Yu zhi-Tao Yin department of Anorectal Disease Shenyang Coloproctology HospitalShenyang 110000Liaoning ProvinceChina department of Neurology Central Hospital of Dalian University of TechnologyDalian 116001Liaoning ProvinceChina department of Acupuncture and Tuina college Liaoning University of Traditional Chinese MedicineShenyang 110032Liaoning ProvinceChina

Fecal incontinence is a common symptom among patients with rectal *** nerve terminal motor latency(PNTML)testing can serve as a reference indicator for predicting the outcomes of rectal prolapse surgery,thereby assisting surgeons in formulating more appropriate surgical *** direct correlation between preoperative PNTML testing results and postoperative fecal incontinence in patients with rectal prolapse remains a contentious issue,necessitating further ***,we analyze the existing publications from both clinical and statistical perspectives to comprehensively evaluate the accuracy of preoperative PNTML testing in rectal prolapse and provide some feasible statistical solutions.

关键词： Rectal prolapse Fecal incontinence Anal manometry Pudendal nerve terminal motor latency Diagnosis Surgical procedures

Surface decoration of mesocarbon microbeads with multifunctional TiNbO_(4-x)@C coating layer as high rate and stable anode of Li-ion batteries

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Rare Metals 2024年第5期43卷 2053-2066页

作者： Jia-Mei Lai zhi-Min Zou Yu Bai Yu-Tao Xing Chun-Hai Jiang fujian Provincial Key Laboratory of functional Materials and Applications Institute of Advanced Energy MaterialsSchool of Materials Science and EngineeringXiamen University of TechnologyXiamen 361024China Shanghai XFH Science and Technology development Co. Ltd.Shanghai 200949China fujian XFH New Energy Materials Co. Ltd.Yong'an 366000China Shenzhen XFH Science and Technology Co. Ltd.Shenzhen 518071China Laboratorio de Microscopia Eletronica de Alta Resolucao Centro de Caracterizagao Avangada Para a Industria de Petroleo(LaMAR/CAIPE)Universidade Federal FluminenseNiteroiRJ 24210-346Brazil

Surface modification of graphite anode with electroactive matters has been proven of a more practical strategy in enhancing the performance of Li-ion batteries than exploring alternative novel anode ***,rutile TiNbO_(4-x) nanoparticles with a tunnel structure are employed as multifunctional decoration substances in combination with a carbon coating layer to improve the rate and cycle properties of mesocarbon microbeads(MCMBs).As compared to pristine MCMB,the Li^(+)diffusion coefficients of the composite anodes are enhanced due to the synergistic effect of TiNbO_(4-x)@***,the overcharge and voltage polarization of the composite anodes at high rate are obviously minimized due to the current sharing effect of the high-potential TiNbO_(4-x).Moreover,the amorphous Li_(y)TiNbO_(4-x) converted from TiNbO_(4-x) in the initial lithiation process can deliver pseudocapacitive capacity to the composite anodes from the second *** of these functions of TiNbO_(4-x)@Ccoating layer have directly contributed to the improved rate and cycle performance of the MCMB/TiNbO_(4-x)@C composite *** one containing 12.0 wt%TiNbO_(4-x) exhibits a high reversible specific capacity of 118 m Ah·g^(-1)at 10C(1C=372 m A·g^(-1)),together with a high capacity retention of 90.9%after 300 cycles at 3C,which are all much superior to those of pristine MCMB.

关键词： Li-ion batteries MCMB TiNbO_(4-x)@C Surface decoration Rate capability

Association between sensitivity to thyroid hormones and non-highdensity lipoprotein cholesterol levels in patients with type 2 diabetes mellitus

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World Journal of Diabetes 2024年第10期15卷 2081-2092页

作者： Xiao-Ye Duan Jun-Ling fu Li-Na Sun zhi-Jing Mu Shuang-Ling Xiu department of Endocrinology Beijing Institute of GeriatricsXuanwu HospitalCapital Medical UniversityBeijing 100053China

BACKGROUND Dyslipidemia and type 2 diabetes mellitus(T2DM)are chronic conditions with substantial public health *** management of lipid metabolism in patients with T2DM is ***,there has been insufficient attention given to the relationship between thyroid hormone sensitivity and dyslipidemia in the T2DM population,particularly concerning non-high-density lipoprotein cholesterol(non-HDL-C).AIM To clarify the association between thyroid hormone sensitivity and dyslipidemia in patients with *** In this cross-sectional study,thyroid hormone sensitivity indices,the thyroid feedback quantile-based index(TFQI),the thyroid-stimulating hormone index(TSHI),the thyrotrophic T4 resistance index(TT4RI),and the free triiodothyronine(FT3)/free thyroxine(FT4)ratio were *** regression analysis was performed to determine the associations between those composite indices and non-HDL-C *** forest variable importance and Shapley Additive Explanations(SHAP)summary plots were used to identify the strength and direction of the association between hyper-non-HDL-C and its major *** Among the 994 participants,389(39.13%)had high non-HDL-C *** regression analysis revealed that the risk of hyper-non-HDL-C was positively correlated with the TFQI(OR:1.584;95%CI:1.088-2.304;P=0.016),TSHI(OR:1.238;95%CI:1.034-1.482;P=0.02),and TT4RI(OR:1.075;95%CI:1.006-1.149;P=0.032)but was not significantly correlated with the FT3/FT4 *** relationships between composite indices of the thyroid system and non-HDL-C levels differed according to *** increased risk of hyper-non-HDL-C was associated with elevated TSHI levels in men(OR:1.331;95%CI:1.003-1.766;P=0.048)but elevated TFQI levels in women(OR:2.337;95%CI:1.4-3.901;P=0.001).Among the analyzed variables,the average SHAP values were highest for TSHI,followed by *** Impaired sensitivity to thyroid hormones was associated with high non-HDL-C levels in

关键词： Non-high-density lipoprotein cholesterol Sensitivity to thyroid hormones Type 2 diabetes mellitus Thyroid feedback quantile-based index Free triiodothyronine/free thyroxine ratio

The Reason of Copper Strip Corrosion in LPG

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The Reason of Copper Strip Corrosion in LPG

鲍曼不动杆菌铁离子摄取机制与基于抑制铁摄取的抗菌策略

甘肃省化学会成立六十周年学术报告会暨二十三届年会

作者： Xing-guo Cheng~(a,b) Li Yang~b, Xing-guo fu~b, zhi-de Hu~a (a: department of Chemistry, Lanzhou University, Lanzhou 730000, P.R. China b: Lanzhou lube oil R(?)D institute of Petrochina, Lanzhou 730060, P.R. China)

Although the caustic sulfur components in LPG have been removed, the process converted the result of copper strip corrosion test from passing into failing sometimes still happens when the LPGs are stored in tanks for several days in some refineries. By analyzing the sulfur species in LPGs that passed and failed in copper strip corrosion test with GC-FPD and GC-MS, It was found that hydrogen sulfide and methanethiol were the main corrosive components. The partial conversion of dimethyl disulfide is the source of hydrogen sulfide and methanethiol in LPG.

关键词： LPG corrosion dimethyl disulfide

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药学学报 2024年第5期59卷 1113-1125页

作者：张芷萌游雪甫庞晶中国医学科学院、北京协和医学院医药生物技术研究所抗感染北京市重点实验室北京100050

细菌耐药一直是抗感染药物研究领域亟待攻克的难题。鲍曼不动杆菌作为引起院内感染的重要病原菌,严重威胁患者的生命健康。近年来,多重耐药、泛耐药,甚至全耐药鲍曼不动杆菌的检出率不断升高,因此开发新的治疗鲍曼不动杆菌感染的策略迫... 详细信息

细菌耐药一直是抗感染药物研究领域亟待攻克的难题。鲍曼不动杆菌作为引起院内感染的重要病原菌,严重威胁患者的生命健康。近年来,多重耐药、泛耐药,甚至全耐药鲍曼不动杆菌的检出率不断升高,因此开发新的治疗鲍曼不动杆菌感染的策略迫在眉睫。铁是鲍曼不动杆菌生存必需的基本元素,也是参与感染进程的重要物质。细菌为了应对宿主铁饥饿现象,发展了一系列铁摄取手段,如分泌铁载体螯合铁、摄取血红素、利用Feo系统转运亚铁等。开发相应的抗菌策略以抑制鲍曼不动杆菌的铁摄取,是应对鲍曼不动杆菌感染的有效手段。本文将从鲍曼不动杆菌铁摄取机制以及基于此机制发展的抗菌策略两个方面进行综述。

关键词：宿主铁饥饿铁摄取鲍曼不动杆菌细菌耐药抗菌策略

Testing the first law of black hole mechanics with gravitational waves

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Science China(Physics,Mechanics & Astronomy) 2024年第10期67卷 76-82页

作者： Chao-Wan-Zhen Wang Jin-Bao Zhu Guo-Qing Huang fu-Wen Shu department of Physics Nanchang UniversityNanchang 330031China Center for Relativistic Astrophysics and High Energy Physics Nanchang UniversityNanchang 330031China GCAP-CASPER Physics DepartmentBaylor UniversityWaco 76798-7316USA

The successful observation of gravitational waves has provided humanity with an additional method to explore the universe,particularly black *** this study,we utilize data from LIGO and Virgo gravitational wave observations to test the first law of black hole mechanics,employing two different *** consider the secondary compact object as a perturbation to the primary black hole before the merger,and the remnant black hole as a stationary black hole after the *** the pre-merger and post-merger analysis,our results demonstrate consistency with the first law,with an error level of approximate 25%at a68%credibility level for *** the full inspiral-merger-ringdown analysis,our results show consistency with the first law of black hole mechanics,with an error level of about 6%at a 68%credibility level and 10%at a 95%credibility level for ***,we observe that the higher the mass ratio of the gravitational wave source,the more consistent our results are with the first law of black hole ***,our study sheds light on the nature of compact binary coalescence and their implications for black hole mechanics.

关键词： gravitational waves black hole mechanics data analysis ringdown

Graphite recycling from spent lithium-ion batteries for fabrication of high-performance aluminum-ion batteries

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Rare Metals 2024年第5期43卷 2161-2171页

作者： Li Wang Chao Wang Jing-Yi Zhang Jia-Cheng Qiu Xu-Wang fu Zi-Rui Zhang Jian-Min Feng Lei Dong Cong-Lai Long de-Jun Li Xiao-Wei Wang Bao Zhang Jia-Feng Zhang Rui-Rui Zhao College of Physics and Materials Science Tianjin Normal UniversityTianjin300387China National Engineering Laboratory for High Efficiency Recovery of Refractory Nonferrous Metals School of Metallurgy and EnvironmentCentral South UniversityChangsha 410083China School of Chemistry South China Normal UniversityGuangzhou510631China

Efficient extraction of electrode components from recycled lithium-ion batteries(LIBs)and their highvalue applications are critical for the sustainable and ecofriendly utilization of *** work demonstrates a novel approach to stripping graphite anodes embedded with Li^(+)from spent LIBs directly in anhydrous ethanol which can be utilized as high efficiency cathodes for aluminum-ion batteries(AIBs).Recycled graphite(RG)with foam morphology and crystal structure defects was obtained under the action of ultrasonic peeling and gas generation reaction between residual lithium-graphite interlayer compound and *** inherent open structure of RG facilitates the intercalation/deintercalation of chloralum anions(AlCl_(4)^(-))and enhances its AIB cathode *** electrochemical measurements revea that the RG cathode has a specific capacity of 123 m Ah·g^(-1)at a current of 5 A·g^(-1),which is 1.55 times higher than tha of unprocessed natural graphite and 1.25 times higher than that of commercial artificial ***,the RG cathode demonstrated remarkable stability,retaining its high particular capacity of 138.15 mAh·g^(-1)even through2000 times at 10 A·g^(-1)in a low-cost electrolyte consisting of an ionic liquid/urea/AlCl_(3)*** work offers a novel approach to reusing of graphite anode waste materials from LIBs.

关键词： Aluminum ion batteries Lithium-ion batteries Graphite anode Recycling

Graphene-loaded nickel−vanadium bimetal oxides as hydrogen pumps to boost solid-state hydrogen storage kinetic performance of magnesium hydride

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Transactions of Nonferrous Metals Society of China 2024年第8期34卷 2645-2657页

作者： Dong-qiang GAO fu-ying WU zhi ZHANG Zi-chuan LU Ren ZHOU Hu ZHAO Liu-ting ZHANG School of Energy and Power Jiangsu University of Science and TechnologyZhenjiang 212003China Instrumental Analysis Center Jiangsu University of Science and TechnologyZhenjiang 212003China School of Mechanical and Aerospace Engineering Nanyang Technological UniversitySingapore 639798Singapore

To modify the thermodynamics and kinetic performance of magnesium hydride(MgH_(2))for solid-state hydrogen storage,Ni_(3)V_(2)O_(8)-rGO(rGO represents reduced graphene oxide)and Ni_(3)V_(2)O_(8)nanocomposites were prepared by hydrothermal and subsequent heat *** beginning hydrogen desorption temperature of 7 wt.%Ni_(3)V_(2)O_(8)-rGO modified MgH_(2)was reduced to 208℃,while the additive-free MgH_(2)and 7 wt.%Ni_(3)V_(2)O_(8)doped MgH_(2)appeared to discharge hydrogen at 340 and 226℃,respectively.A charging capacity of about 4.7 wt.%H_(2)for MgH_(2)+7 wt.%Ni_(3)V_(2)O_(8)-rGO was achieved at 125℃ in 10 min,while the dehydrogenated MgH_(2)took 60 min to absorb only 4.6 wt.%H_(2)at 215℃.The microstructure analysis confirmed that the in-situ generated Mg_(2)Ni/Mg_(2)N_(i)H_(4) and metallic V contributed significantly to the enhanced performance of MgH_(2).In addition,the presence of rGO in the MgH_(2)+7 wt.%Ni_(3)V_(2)O_(8)-rGO composite reduced particle aggregation tendency of Mg/MgH_(2),leading to improving the cyclic stability of MgH_(2)during 20 cycles.

关键词： hydrogen storage properties MgH_(2) graphene-loaded Ni−V bimetal oxides catalytic mechanism