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Near earth Vortices Driving of Field Aligned Currents Based on Magnetosphere Multiscale and Swarm Observations

空间科学学报 2019年第1期39卷 9-17页

作者： ZHANG C SHeN C YANG Y Y DUNLOP M W TI S RUSSeLL C T LüHR H BURCH J L LINDQVIST P A TORBeRT R B friis-christensen e State Key Laboratory of Space Weather National Space Science Center College of earth Science University of Chinese Academy of Sciences College of Science Harbin Institute of Technology Institute of China Seismological Bureau Crustal Stress Space Science Institute School of Astronautics Beihang University Rutherford Appleton Laboratory University of California German Research Center For Geosciences German Research Center for Geosciences Southwest Research Institute Royal Institute of Technology University of New Hampshire Danish National Space Center

A long-standing mystery in the study of Field-Aligned Currents(FACs) has been that: how the currents are generated and why they appear to be much stronger at high altitudes than in the ionosphere. Here we present two events of magnetotail FACs observed by the Magnetospheric Multiscale Spacecraft(MMS) on 1 st July and 14 th July 2016, to show how the Substorm Current Wedges(SCW) were formed. The results show that particles were transferred heading towards the earth during the expansion phase of *** azimuthal flow formed clockwise(counter-clockwise) vortex-like motion, and then generated downward(upward) FACs on the tailward/poleward side of the distorted field with opposite vorticity on their earthward/equatorward side. We also analyzed the Region 1 FACs observed by the earth explorer Swarm spacecraft on 1 st July 2016 and found that they were associated with FACs observed by MMS, although differing by a factor of 10. This difference suggests that either there was the closure of the currents at altitudes above 500 km or the currents were not strictly parallel to B and closed at longitudes away from where they were generated.

关键词： Substorm current wedge Magnetosphere Field-aligned currents Flow vorticity Multiple spacecraft measurements

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NeCAB family of neuronal calcium-binding proteins in health and disease

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Neural Regeneration Research 2025年第5期20卷 1236-1243页

作者： Diones Bueno Michael K.e.Schafer Sudena Wang Michael J.Schmeisser Axel Methner Institute for Molecular Medicine University Medical Center of the Johannes Gutenberg-UniversityMainzGermany Department of Anesthesiology University Medical Center of the Johannes Gutenberg-UniversityMainzGermany Institute of Anatomy University Medical Center of the Johannes Gutenberg-UniversityMainzGermany

The N-terminal eF-hand calcium-binding proteins 1–3(NeCAB1–3) constitute a family of predominantly neuronal proteins characterized by the presence of at least one eF-hand calcium-binding domain and a functionally less well characterized C-terminal antibiotic biosynthesis monooxygenase domain. All three family members were initially discovered due to their interactions with other proteins. NeCAB1 associates with synaptotagmin-1, a critical neuronal protein involved in membrane trafficking and synaptic vesicle exocytosis. NeCAB2 interacts with predominantly striatal G-protein-coupled receptors, while NeCAB3 partners with amyloid-β A4 precursor protein-binding family A members 2 and 3, key regulators of amyloid-β production. This demonstrates the capacity of the family for interactions with various classes of proteins. NeCAB proteins exhibit distinct subcellular localizations: NeCAB1 is found in the nucleus and cytosol, NeCAB2 resides in endosomes and the plasma membrane, and NeCAB3 is present in the endoplasmic reticulum and Golgi apparatus. The antibiotic biosynthesis monooxygenase domain, an evolutionarily ancient component, is akin to atypical heme oxygenases in prokaryotes but is not wellcharacterized in vertebrates. Prokaryotic antibiotic biosynthesis monooxygenase domains typically form dimers, suggesting that calcium-mediated conformational changes in NeCAB proteins may induce antibiotic biosynthesis monooxygenase domain dimerization, potentially activating some enzymatic properties. However, the substrate for this enzymatic activity remains uncertain. Alternatively, calcium-mediated conformational changes might influence protein interactions or the subcellular localization of NeCAB proteins by controlling the availability of protein–protein interaction domains situated between the eF hands and the antibiotic biosynthesis monooxygenase domain. This review summarizes what is known about genomic organization, tissue expression, intracellular localization, interac

关键词： calcium eF hand mitochondria nervous system signal transduction

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electrochemical Reaction Processes of Niobium Ions in FLINAK melt

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International Journal of Minerals,Metallurgy and Materials 1999年第2期13卷 83-89页

作者： Wang, Xindong Duan, Shuzhen christensen, e. Bjerrum, N.J. Ito, Y. Metallurgy School University of Science and Technology Beijing Beijing 100083 China Materials Science Group Chemistry Department A Technical University of Denmark DK-2800 Lyngby Denmark Department of energy Science and engineering Kyoto University Kyoto 606 Japan

ThecathodicProcessmechanismofniobiumreductionfromchloride-fluorideandfiuoridemeltshasbeenstudiedindetail[l-],batth***,threehoesofmodelshaVebeenPutforwardtoexplaintheelectrochemic... 详细信息

ThecathodicProcessmechanismofniobiumreductionfromchloride-fluorideandfiuoridemeltshasbeenstudiedindetail[l-],batth***,threehoesofmodelshaVebeenPutforwardtoexplaintheelectrochemic...

关键词： electrochemistry molten Salt FLINAK niobium reduction

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Recent Advancements in the Optimization Capacity Configuration and Coordination Operation Strategy of Wind-Solar Hybrid Storage System

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energy engineering 2025年第1期122卷 285-306页

作者： Hongliang Hao Caifeng Wen Feifei Xue HaoQiu Ning Yang Yuwen Zhang Chaoyu Wang edwin e.Nyakilla Department of New energy Storage Peking University Ordos Research Institute of EnergyOrdos017010China School of energy and Power engineering Inner Mongolia University of TechnologyHohhot010080China Key Laboratory of Wind energy and Solar energy Utilization Technology Inner Mongolia University of TechnologyHohhot010051China

Present of wind power is sporadically and cannot be utilized as the only fundamental load of energy *** paper proposes a wind-solar hybrid energy storage system(HeSS)to ensure a stable supply grid for a longer period.A multi-objective genetic algorithm(MOGA)and state of charge(SOC)region division for the batteries are introduced to solve the objective function and configuration of the system capacity,***/Simulink was used for simulation *** optimization results show that for a 0.5 MW wind power and 0.5 MW photovoltaic system,with a combination of a 300 Ah lithium battery,a 200 Ah lead-acid battery,and a water storage tank,the proposed strategy reduces the system construction cost by approximately 18,000 ***,the cycle count of the electrochemical energy storage systemincreases from4515 to 4660,while the depth of discharge decreases from 55.37%to 53.65%,achieving shallow charging and discharging,thereby extending battery life and reducing grid voltage fluctuations *** proposed strategy is a guide for stabilizing the grid connection of wind and solar power generation,capability allocation,and energy management of energy conservation systems.

关键词： electric-thermal hybrid storage modal decomposition multi-objective genetic algorithm capacity optimization allocation operation strategy

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Three-dimensional models:from cell culture to Patient-Derived Organoid and its application to future liposarcoma research

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Oncology Research 2025年第1期33卷 1-13页

作者： SAYUMI TAHARA SYDNeY ReNTSCH FeRNANDA COSTAS CASAL De FARIA PATRICIA SARCHeT ROMA KARNA FeDeRICA CALORe RAPHAeL e.POLLOCK Department of Surgery Division of Surgical OncologyThe James Comprehensive Cancer CenterThe Ohio State University Wexner Medical CenterColumbusOH 43210USA Department of Cancer Biology and Genetics The James Comprehensive Cancer CenterThe Ohio State University Wexner Medical CenterColumbusOH 43210USA

Liposarcoma is one of the most common soft tissue sarcomas,however,its occurrence rate is still rare compared to other *** to its rarity,in vitro experiments are an essential approach to elucidate liposarcoma *** cell culture-based research(2D cell culture)is still playing a pivotal role,while several shortcomings have been recently under *** vivo,mouse models are usually adopted for pre-clinical analyses with expectations to overcome the issues of 2D cell ***,they do not fully recapitulate human dedifferentiated liposarcoma(DDLPS)***,three-dimensional(3D)culture systems have been the recent research focus in the cell biology field with the expectation to overcome at the same time the disadvantages of 2D cell culture and in vivo animal models and fill in the gap between *** the liposarcoma rarity,we believe that 3D cell culture techniques,including 3D cell cultures/co-cultures,and Patient-Derived tumor Organoids(PDOs),represent a promising approach to facilitate liposarcoma investigation and elucidate its molecular mechanisms and effective therapy *** this review,we first provide a general overview of 3D cell cultures compared to 2D cell *** then focus on one of the recent 3D cell culture applications,Patient-Derived Organoids(PDOs),summarizing and discussing several PDO ***,we discuss the current and future applications of PDOs to sarcoma,particularly in the field of liposarcoma.

关键词： Cell culture Liposarcoma Patient-Derived Organoid(PDO) Spheroid Three-dimensional(3D)cell culture

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Merging bound states in the continuum in an open acoustic resonator

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 124-131页

作者： Lujun Huang Bin Jia Artem S.Pilipchuk Sibo Huang Chen Shen Almas F.Sadreev Yong Li Andrey e.Miroshnichenko School of Physics and electronic Sciences East China Normal University Institute of Acoustics Tongji University L.V.Kirensky Institute of Physics Department of Mechanical engineering Rowan University School of engineering and Technology University of New South Wales at Canberra

Bound states in the continuum （BICs） are perfectly localized resonances despite embedding in the continuum ***,an isolated BIC is very sensitive to the structure ***,we report merging acoustic BICs in a single open resonator,robust against the structure *** find that both symmetry-protected BIC and Friedrich-Wintgen BIC are sustained in a single coupled waveguide-resonator *** varying the height and length of the resonator,these two BICs move toward each other and merge into a single one at a critical *** to an individual BIC,the merged BIC is robust against fabrication error because its Q-factor is proportional to ΔL-4,whereΔL embodies the structure *** essence of this extraordinary phenomenon is perfectly explained by the two-and three-level approximations of the effective nonHermitian ***,we present direct experimental demonstrations of the moving and merging of BICs in a coupled 3D waveguide-resonator,which are evidenced by the vanishing of the linewidth of Fano resonance in the transmission *** results may find exciting applications in designing high-quality acoustic sources,sensors and filters.

关键词： acoustic resonances bound state in the continuum high-Q resonances

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enhancing perianal disease management with integrated physical and psychological approaches

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World Journal of Clinical Cases 2025年第2期13卷 59-63页

作者： Uchenna e Okpete Haewon Byeon Department of Digital Anti-aging Healthcare(BK21) Inje UniversityGimhae 50834South Korea

This article provides a comprehensive analysis of the study by Hou et al,focusing on the complex interplay between psychological and physical factors in the postoperative recovery(POR)of patients with perianal *** study sheds light on how illness perception,anxiety,and depression significantly influence recovery *** et al developed a predictive model that demonstrated high accuracy in identifying patients at risk of poor *** article explores the critical role of pre-operative psychological assessment,highlighting the need for mental health support and personalized recovery plans in enhancing POR quality.A multidisciplinary approach,integrating mental health professionals with surgeons,anesthesiologists,and other specialists,is emphasized to ensure comprehensive care for *** study’s findings serve as a call to integrate psychological care into surgical practice to optimize outcomes for patients with perianal diseases.

关键词： Perianal disease Post-operative recovery Anxiety Depression Pain management emotional well-being Multidisciplinary approach

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太阳周期长度:太阳活动性与气候紧密联系的一个“指示器”

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世界科学 1992年第9期 39-40页

作者： e.friis.christensen 吴继星

科学家进行了许多尝试,力图探讨CO2大量释放到大气中后对气候的影响。从现实情况考虑,在全球范围进行实验是不可能的,物理学理论的证据就是依赖模型模拟和观察。模型模拟需要某种假设,而获得大量基本数据则需长时间的观察。太阳辐射是... 详细信息

科学家进行了许多尝试,力图探讨CO2大量释放到大气中后对气候的影响。从现实情况考虑,在全球范围进行实验是不可能的,物理学理论的证据就是依赖模型模拟和观察。模型模拟需要某种假设,而获得大量基本数据则需长时间的观察。太阳辐射是与地球气候相关的一个最基本因素。这是无法准确知道的一个参数。埃迪（eddy）指出,太阳活动性与全球气候的某些“指示器”之间的长期关系可能是由太阳辐照度的变化所引起的。但是,只有在当今人造卫星时代,才能测得有关太阳辐照度的可靠

关键词：太阳地磁长期变化恒星磁学周期变化太阳辐照度气候指示器活动性

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An efficient Boron Source Activation Strategy for the Low‑Temperature Synthesis of Boron Nitride Nanotubes

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Nano-Micro Letters 2025年第1期17卷 548-558页

作者： Ying Wang Kai Zhang Liping Ding Liyun Wu Songfeng e Qian He Nanyang Wang Hui Zuo Zhengyang Zhou Feng Ding Yue Hu Jin Zhang Yagang Yao National Laboratory of Solid State Microstructures College of Engineering and Applied SciencesJiangsu Key Laboratory of Artificial Functional Materialsand Collaborative Innovation Center of Advanced MicrostructuresNanjing UniversityNanjing 210093People’s Republic of China School of electronic Information and Artificial Intelligence Shaanxi University of Science&TechnologyXian 710000People’s Republic of China College of Bioresources Chemical and Materials engineering Shaanxi University of Science&TechnologyXian 710000People’s Republic of China Key Laboratory of Carbon Materials of Zhejiang Province College of Chemistry and Materials EngineeringWenzhou UniversityWenzhou 325000People’s Republic of China Shenzhen Institutes of Advanced Technology Chinese Academy of SciencesShenzhen 518000People’s Republic of China College of Chemical and Molecular engineering Peking UniversityBeijing 100871People’s Republic of China

Lowering the synthesis temperature of boron nitride nanotubes(BNNTs)is crucial for their *** primary reason for adopting a high temperature is to enable the effective activation of highmelting-point solid *** this study,we developed a novel approach for efficiently activating boron by introducing alkali metal compounds into the conventional MgO–B *** approach can be adopted to form various low-melting-point AM–Mg–B–O growth *** growth systems have improved catalytic capability and reactivity even under low-temperature conditions,facilitating the synthesis of BNNTs at temperatures as low as 850℃.In addition,molecular dynamics simulations based on density functional theory theoretically demonstrate that the systems maintain a liquid state at low temperatures and interact with N atoms to form BN *** findings offer novel insights into the design of boron activation and are expected to facilitate research on the low-temperature synthesis of BNNTs.

关键词： Boron nitride nanotubes Low-temperature Boron activation Density functional theory

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Determination of Oxide in FLINAK Melt by electrochemical Titration Technique

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Rare Metals 1993年第2期12卷 97-102页

作者：王新东段淑贞 christensen e. Von Barner J.H. Bjerrum N.J. University of Science and Technology Beijing Beijing 100083China The Technical University of Denmark DK-2800 LyngbyDenmark

The use of K2NbF7 as a probe solute for the cyclic voltammetric determination of oxide in FLINAK melts was studied and demonstrated. This method is based on a complex reaction and the peak current density of NbF72- reduction. The reaction constant was determined to be very large at 973 K. A cyclic voltammetric standard addition experiment was also employed to determine the amount of oxide in FLNAK melt. The oxide content of FLINAK melts is equal to the amount of Nb(V) added minus the amount of NbF72- which is obtained from the voltammogram.

关键词： electrochemistry Liquid metals Niobium Oxides Titration

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