检索结果-南通市图书馆

常染色体显性遗传性感觉神经病变伴慢性咳嗽和胃食管反流:2个染色体3p22-p24相关家族的临床特征

世界核心医学期刊文摘（神经病学分册） 2006年第6期2卷 54-54页

作者： Spring P.j. kok C. Nicholson G.A. 高宗恩 Department of Neurology Concord Hospital Hospital Road Concord NSW 2139 Australia Dr.

Autosomal dominant hereditary sensory neuropathy (HSN I) is a clinically and genetically heterogeneous group of disorders, and in some families it is due to mutations in the serine palmitoyltransferase (SPTLC1) gene. We have characterized two families with HSN I associated with cough and gastro-oesophageal reflux (GOR). From a large Australian family, 27 individuals and from a smaller family, 11 individuals provided clinical information and blood for genetic analysis. Affected individuals had an adult onset of paroxysmal cough, GOR and distal sensory loss. Cough could be triggered by noxious odours or by pressure in the external auditory canal (Arnold’s ear-cough reflex). Other features included throat clearing, hoarse voice, cough syncope and sensorineural hearing loss. Neurophysiological and pathological studies demonstrated a sensory axonal neuropathy. Gastric emptying studies were normal, and autonomic function and sweat tests were either normal or showed distal hypohidrosis. Cough was likely to be due to a combination of denervation hypersensitivity of the upper airways and oesophagus, and prominent GOR. Most affected individuals were shown on 24 h ambulatory oesophageal pH monitoring to have multiple episodes of GOR, closely temporally associated with coughing. Hoarse voice was probably attributable to acid-induced laryngeal damage, and there was no evidence of vocal cord palsy. No other cause for cough was found on most respiratory or otorhinological studies. Linkage to chromosome 3p22-p24 has been found in both families, with no evidence of linkage to loci for known HSN I, autosomal dominant hereditary motor and sensory neuropathy, hereditary GOR or triple A syndrome. These families represent a genetically novel variant of HSN I, with a distinctive cough owing to involvement of the upper aerodigestive tract.

关键词：常染色体显性遗传性感觉神经病变胃食管反流慢性咳嗽临床特征个染色体家族感觉神经性耳聋外耳道压力

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

快速评价髂动脉栓塞的多普勒频谱分析与股动脉直接测量

引用

实用医学影像杂志 1998年第1期 8-8页

作者： j. Adam van der Vliet Willem N. j. C. Van Asten j.se' H. Haenen Albert P. M. Boll frans G. M. Buskens 郝彦威

为了减轻临床工作负担并提高髂动脉系统无创性血液动力学评价效果,需要选择合适的病人。利用传统的股动脉压直接穿刺测量技术和计算机多普勒频谱分析,研究了股动脉中的血流速率。为了证实50％或以上的狭窄,上述两种快速评价髂动脉栓塞... 详细信息

为了减轻临床工作负担并提高髂动脉系统无创性血液动力学评价效果,需要选择合适的病人。利用传统的股动脉压直接穿刺测量技术和计算机多普勒频谱分析,研究了股动脉中的血流速率。为了证实50％或以上的狭窄,上述两种快速评价髂动脉栓塞的试验均与利用2.5的高峰收缩速率比值的双重超声成像做了比较。在一系列怀疑有髂动脉栓塞性疾病的17例患者(34根髂动脉)中,发现两种方法与双重扫描比较时。

关键词：髂动脉快速评价多普勒频谱股动脉压直接测量动脉栓塞性疾病血流速率峰收缩双重扫描无创性

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Coastal wetlands in Lianyungang,j.angsu Province,China:probably the most important site globally for the Asian Dowitcher(Limnodromus semipalmatus)

引用

Avian Research 2021年第3期12卷 364-374页

作者： Ziyou Yang j.ng Li Yongxiang Han Chris j.Hassell Kar-Sin Katherine Leung David S.Melville Yat-tung Yu Lin Zhang Chi-Yeung Choi Spoon-Billed Sandpiper(Shanghai)Environmental Protection Technology Co. Ltd.Shanghai 201100China Lianyungang Xugou Primary School Lian-yungang 222042China Global Flyway Network PO Box 3089BroomeWA 6725Australia Hong Kong Waterbirds Ringing Group Mai Po Nature ReserveHong KongChina 1261 Dovedale Road RD 2 WakefieldNelson 7096New Zealand Hong Kong Bird Watching Society 7CV Ga Building532 Castle Peak RoadLai Chi KokKowloonHong KongChina School of Environmental Science and Engineering Southern University of Science and TechnologyShenzhen 518055China

Background:Despite an increasing number of surveys and a growing interest in birdwatching,the population and distribution of Asian Dowitcher(Limnodromus semipalmatus),a species endemic to the East Asian-Australasian and Central Asian Flyways,remains poorly understood,and published information about the species is largely *** boreal spring 2019,over 22,432 Asian Dowitchers were recorded in a coastal wetland at Lianyungang,j.angsu Prov-ince,China,constituting 97.5%of its estimated global ***:In 2019 and 2020,we conducted field surveys at Lianyungang to determine the numbers of Asian Dow-itchers using the area during both southward and northward *** also assessed the distribution and abun-dance of Asian Dowitchers elsewhere along the China coast by searching literature and consulting expert ***:The coastal wetlands of Lianyungang are the most important stopover site for Asian Dowitchers during both northward and southward migrations;they supported over 90%of the estimated global population during north-ward migration in two consecutive years(May 2019 and 2020).This area also supported at least 15.83%and 28.42%(or 30.74%and 53.51%using modelled estimates)of the global population during southward migration in 2019 and 2020 *** wetlands in the west and north of Bohai Bay also have been important stopover sites for the species since the *** comprehensive,long-term monitoring data are lacking,available evidence sug-gests that the population of the species may have ***:The high concentration of Asian Dowitchers at Lianyungang during migration means the species is highly susceptible to human disturbances and natural stochastic *** coastal wetlands of Lianyungang should be protected and potentially qualify for inclusion in China’s forthcoming nomination for World Heritage listing of Migratory Bird Sanctuaries along the Coast of Yellow Sea-Bohai Gulf of China(Phase II)in ***

关键词： Lianyungang Limnodromus semipalmatus Shorebird Stopover ecology Yellow Sea World Heritage

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The enhanced X-ray Timing and Polarimetry mission—eXTP

引用

Science China(Physics,Mechanics & Astronomy) 2019年第2期62卷 3-27页

作者： ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu Fangj.n Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga j.ri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu j.an j.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso j.rg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen j.rome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino j.séLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long j. ShuMei j.a WeiChun j.ang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu Xiaoj.ng Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte j.nLu Qu Alexandre Rachevski Irina Rashevskaya j.rome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng j.angBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang j.an Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen j.rn Wilms ShaoLin Xiong j.aWei Yang Sheng Yang Yanj. Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej.A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao Shij.e Zheng Yu Peng Zhou Key Laboratory for Particle Astrophysics Institute of High Energy PhysicsChinese Academy of Sciences Institut für Astronomie und Astrophysik Eberhard Karls Universität INAF-Istituto di Astrofisica e Planetologia Spaziali INFN-Roma Tor Vergata Via della Ricerca Scientifica 1 Department of Engineering Physics and Center for Astrophysics Tsinghua University DTU Building 327DK-2800 Kongens Institute of Space Sciences 08193 Cerdanyola del Valles Institut d’Estudis Espacials de Catalunya Sezione di Pisa Istituto Nazionale di Fisica NucleareLargo Bruno Pontecorvo3 Department of Astronomy University of Genevachemin d’Ecogia 16 Osservatorio di Astrofisica e Scienza Dello Spazio di Bologna Istituto Nazionale di Astofisica Astronomical Institute Czech Academy of Sciences Max Planck Institute for Extraterrestrial Physics Giessenbachstr.1 CEA Paris-Saclay/IRFU Beij.ng Institute of Spacecraft System Engineering CAST Osservatorio Astronomico di Brera Istituto Nazionale di Astofisica Space Research Center Polish Academy of Sciences Key Laboratory of Advanced Material Microstructure of Education Ministry of China Institute of Precision Optical EngineeringSchool of Physics Science and EngineeringTongji University Department of Physics and Center for Astrophysics Tsinghua University Universita’degli Studi di Udine Via delle Scienze 206 Mullard Space Science Laboratory University College London Department of Nuclear and Particle Physics University of Geneva SRON Netherlands Institute for Space Research Politecnico di Milano Sezione di Perugia Istituto Nazionale di Fisica Nucleare Dipartimento di Fisica e Chimica Fondazione Bruno Kessler Dr.Karl Remeis-Observatory and Erlangen Centre for Astroparticle Physics Universität Erlangen-Nürnberg University of Pavia Department of ElectronicsInformation and Biomedical Engineering and INFN Pavia Sezione di Torino Istituto Nazionale di Fisica NucleareVia Pietro Giuria1 Department of Physics and Astronomy University of Leicester Sezione di Trieste Istituto Nazionale di Fisica Nucleare

In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic obj.cts. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave *** paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment.

关键词： X-ray instrumentation X-ray polarimetry X-ray timing space mission:eXTP

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

TAVI术前应用MDCT评估主动脉根部及主动脉瓣以获得心动周期中的最佳成像时间点

引用

国际医学放射学杂志 2015年第5期 492-492页

作者： T.j.rencak j.Turek B.L.j.H.Kietselaer C.Mihl M.kok V.G.V.A.van Ommen 宋茜 Department of Radiology Maastricht University Medical Center

摘要目的通过综合评估主动脉根部以确定制定经导管主动脉瓣置换术治疗计划的最佳成像时间点。方法回顾连续64例行TAVI术前评估的病人资料,所有病人均已行带心电门控的多层螺旋CT(MDCT)检查。在心动周期11个不同时间点评估主动脉根部的1... 详细信息

摘要目的通过综合评估主动脉根部以确定制定经导管主动脉瓣置换术治疗计划的最佳成像时间点。方法回顾连续64例行TAVI术前评估的病人资料,所有病人均已行带心电门控的多层螺旋CT(MDCT)检查。在心动周期11个不同时间点评估主动脉根部的18个不同参数,确定最大或最小测量尺寸的时间点,然后评估与其他时间点尺寸的差异,比较基于不同测量的理论假体大小。结果在心动周期的

关键词：心动周期时间点成像时间主动脉大动脉 TAVI MDCT

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Nat Genet:单细胞分析解开结直肠癌细胞的神秘面纱

引用

现代生物医学进展 2017年第15期17卷 I0003-I0003页

作者： Huipeng Li, Elise T Courtois, Debarka Sengupta, Yuliana Tan Shyam Prabhakar Elise T Courtois, Yuliana Tan Paul Robson Debarka Sengupta kok Hao Chen, j.lene j.e Lin Goh Paul j.ngj.on Choi Say Li Kong, Axel M Hillmer Iain Beehuat Tan Clarinda Chua Iain Beehuat Tan Lim Kiat Hon Wah Siew Tan Mark Wong Lawrence j.K Wee Iain Beehuat Tan Paul Robson Paul Robson Paul Robson Computational and Systems Biology Genome Institute of Singapore Singapore Developmental Cellomics Laboratory Genome Institute of Singapore Singapore Department of Computer Science and Engineering and Center for Computational Biology Indraprastha Institute of Information Technology Delhi India Synthetic Biology Genome Institute of Singapore Singapore Cancer Therapeutics and Stratified Oncology Genome Institute of Singapore Singapore Department of Medical Oncology National Cancer Centre Singapore Singapore Department of Pathology Singapore General Hospital Singapore Department of Colorectal Surgery Singapore General Hospital Singapore Data Analytics Department Institute for Infocomm Research Singapore Program in Cancer and Stem Cell Biology Duke-NUS Medical School Singapore The j.ckson Laboratory for Genomic Medicine Farmington Connecticut USA Department of Genetics and Genome Sciences Institute for Systems Genomics University of Connecticut Farmington Connecticut USA Department of Biological Sciences National University of Singapore Singapore.

结合单细胞基因组学和计算机技术，一个研究团队（包括来自杰克逊实验室（j.x）单细胞生物学主任Paul Robson博士在内）鉴定出了11种结直肠癌肿瘤的癌细胞组成及邻近的非癌细胞。这对于更好的肿瘤靶向诊断和治疗很重要。”使用单细胞测... 详细信息

结合单细胞基因组学和计算机技术，一个研究团队（包括来自杰克逊实验室（j.x）单细胞生物学主任Paul Robson博士在内）鉴定出了11种结直肠癌肿瘤的癌细胞组成及邻近的非癌细胞。这对于更好的肿瘤靶向诊断和治疗很重要。”使用单细胞测序。”j.X科学家、这篇发表在Nature Genetics上的文章共同第一作者Elise Courtois说道。”我们可以根据肿瘤中的细胞组成将结直肠癌进一步分类。因为每种亚型的肿瘤病人生存率存在差别，我们的方法将为肿瘤医生提供更多的关于肿瘤预后和治疗的信息。”

关键词：单细胞分析结直肠癌癌细胞 Nat 细胞组成肿瘤病计算机技术细胞生物学

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

SurePath、ThinPrep和传统细胞学3种方法常规筛查阴性后的宫颈癌发病率的研究：基于人群研究

引用

英国医学杂志中文版 2018年第3期21卷 177-177页

作者： Kirsten Rozemeij.r Steffie K Naber Corine Penning Lucy H Overbeek Caspar W N Looman Inge M C M de kok Suzette M Matthij.se Matej.a Rebolj.Folkert j.van Kemenade Marj.lein van Ballegooij.n 张雪芳王淑珍不详首都医科大学附属北京朝阳医院妇产科

摘要目的比较3种不同筛查方法即传统细胞学、液基细胞学（Sure Path和Thin Prep）检测阴性后72个月内宫颈癌的累积发病率。设计以人群为基础的回顾性队列研究。背景从2000年1月-2013年3月在荷兰全国范围内网络登记的有组织病理学或细... 详细信息

摘要目的比较3种不同筛查方法即传统细胞学、液基细胞学（Sure Path和Thin Prep）检测阴性后72个月内宫颈癌的累积发病率。设计以人群为基础的回顾性队列研究。背景从2000年1月-2013年3月在荷兰全国范围内网络登记的有组织病理学或细胞病理学情况的宫颈癌数据。

关键词：细胞学屏蔽学习人口癌症样品

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：