检索结果-南通市图书馆

npj Computational Materials 2023年第1期9卷 1227-1236页

作者： Yihang Li Ruijie Zhu Yuanqing Wang lingyan feng Yi Liu Materials Genome Institute Shanghai UniversityShanghai 200444China Department of Materials Science and Engineering Northwestern UniversityEvanstonIL 60208USA Shanghai Engineering Research Center of Organ Repair Shanghai UniversityShanghai 200444China Zhejiang Laboratory Hangzhou 311100China

In data-driven materials design where the target materials have limited data,the transfer machine learning from large known source materials,becomes a demanding strategy especially across different crystal *** this work,we proposed a deep transfer learning approach to predict thermodynamically stable perovskite oxides based on a large computational dataset of spinel *** deep neural network(DNN)source domain model with“Center-Environment”(CE)features was first developed using the formation energy of 5329 spinel oxide structures and then was fine-tuned by learning a small dataset of 855 perovskite oxide structures,leading to a transfer learning model with good transferability in the target domain of perovskite *** on the transferred model,we further predicted the formation energy of potential 5329 perovskite structures with combination of 73 *** the criteria of formation energy and structure factors including tolerance factor(0.7

关键词： perovskite oxides transfer

Electrochemically and DNA-triggered cell release from ferrocene/β-cyclodextrin and aptamer modified dual- functionalized graphene substrate

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2015年第3期8卷 887-899页

作者： lingyan feng Wen Li Jinsong Ren Xiaogang Qu Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun 130022 P. R. China University of Chinese Academy of Sciences Beijing 100039 P. R. China

Here we report a dual-functionalized electrochemical substrate to trigger cancer cells release based on the supramolecular interaction between β-cyclodextrin （β-CD） and Fc on clinical trial II aptamer AS1411 functionalized graphene platform. On one hand, the host-guest interaction can be reversible electrochemically controlled to realize cancer cells capture/release, and 1-adamantylamine binding can further amplify this surface change by competing interaction with β-CD. On the other hand, the AS1411 aptamer and its complementary DNA （cDNA） also can be used as a switchable anchor for cell adhesion. Our work gives an example for label-free, multi-functionalized triggered cell release based on aptamer and β-CD/graphene-modified surface and this multi-ways for cell catch-and-release on graphene modified surface also provides their potential biomedical application.

关键词： cell release ferrocene/β-cyclodextrin AS1411 graphene

Flocculating Properties and Production of the Compound Bioflocculant by Rhizobium Radiobacter F2 and Bacillus Sphaeicus F6

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Harbin Institute of Technology(New Series) 2015年第4期22卷 20-26页

作者： Lixin Li lingyan feng Fang Ma Qianshen Zhao State Key Laboratory of Urban Water Resource and Environment School of Municipal and Environmental EngineeringHarbin Institute of Technology School of Environment and Chemical Engineering Heilongjiang University of Science and Technology School of Energy and Civil Engineering Harbin University of Commerce

A compound bioflocculant CBF,produced by mixed culture of Rhizobium radiobacter F2 and Bacillus sphaeicus F6, was investigated with regard to its production and flocculating properties. The optimization of the culture medium constituents including carbon source,nitrogen source and C / N ratio,metal ions and ionic strength on CBF production were studied. Flocculating properties of CBF were examined by a series of experiments and CBF had good flocculating activities in kaolin suspension with divalent cations and stable over wide range of p H. Studies of the flocculating properties revealed that the flocculation could be stimulated by cations Ca2+,Mg2+,Fe2+,Al3+and Fe3+. In addition,it was stable at 4-30 ℃ in the presence of Ca Cl2. It was found to be effective for flocculation of a kaolin suspension under neutral and weak alkaline conditions( p H 7. 0- 9. 0),and flocculating activities of higher than 95% were obtained when the CBF concentrations among 6- 14 mg / L at p H 8. 0. The results of this study indicate that CBF is a potential replacement of conventional synthetic flocculants and is widely applied in water treatment and downstream processing of food and fermentation industries.

关键词： compound bioflocculant Rhizobium radiobacter Bacillus sphaeicus production flocculating activity

Correlation between women's sub-health and reproductive diseases with pregnancies and labors

在线全文

学校读者我要写书评

暂无评论

Journal of Traditional Chinese Medicine 2014年第4期34卷 465-469页

作者： Xiaojuan Xu Qian Zeng Hong Ding lingyan feng Linwen Deng Department of Gynecology Clinical College of MedicineChengdu University of Traditional Chinese Medicine Department of Gynecology Affiliated Hospital of Chengdu University of Traditional Chinese Medicine The National Center for Traditional Chinese Medicine Clinical Trials Research Affiliated Hospital of Chengdu University of Traditional Chinese Medicine Women's Health Training Center of Tianjin Municipal Women and Children's Health Care Center

OBJECTIVE: To investigate whether female sub-health conditions and reproductive diseases areassociated with pregnancies and ***: A cross-sectional survey was performed by using a structured questionnaire. A total of 1343 women aged 35 years or younger in six urban areas of Chengdu were included in the *** to the Screening Criteria of sub-health conditions, these women were categorized into three groups: postpartum healthy group,sub-healthy group, and reproductive disease group. Data were double-entered using EpiData and the nanalyzed by ***: Pregnancy and labor were correlated with postpartum sub-health conditions. The number of pregnancies was negatively correlated with women's postnatal health but was positively correlated with the incidence of postpartum reproductive ***: The number of pregnancies and labors is probably an important factor leading to sub-health conditions and the occurrence of reproductive diseases in women. Avoiding or reducing unwanted pregnancies and labors, enhancing the awareness of health among child bearing-age women are effective measures for preventing sub-health conditions.

关键词： Sub-health Reproductive disease Pregnancy Labor Correlation Medicine Chinese traditional

High-throughput experiments facilitate materials innovation:A review

在线全文

学校读者我要写书评

暂无评论

Science China(Technological Sciences) 2019年第4期62卷 521-545页

作者： LIU Yi Hao HU ZiHeng SUO ZhiGuang HU LianZhe feng lingyan GONG XiuQing LIU Yi ZHANG JinCang Materials Genome Institute Shanghai University Chongqing Key Laboratory of Green Synthesis and Application College of Chemistry Chongqing Normal University

Since the Material Genome Initiative(MGI) was proposed, high-throughput based technology has been widely employed in various fields of materials science. As a theoretical guide, material informatics has been introduced based on machine learning and data mining and high-throughput computation has been employed for large scale search, narrowing down the scope of the experiment trials. High-throughput materials experiments including synthesis, processing, and characterization technologies have become valuable research tools to pin down the prediction experimentally, enabling the discovery-to-deployment of advances materials more efficiently at a fraction of cost. This review aims to summarize the recent advances of high-throughput materials experiments and introduce briefly the development of materials design based on material genome concept. By selecting representative and classic works in the past years, various high-throughput preparation methods are introduced for different types of material gradient libraries, including metallic, inorganic materials, and polymers. Furthermore, high-throughput characterization approaches are comprehensively discussed, including both their advantages and limitations. Specifically, we focus on high-throughput mass spectrometry to analyze its current status and challenges in the application of catalysts screening.

关键词： Material Genome Initiative(MGI) high-throughput material development materials synthesis materials characterization

In-situ formation of“electron conductive wires”threaded ZIF-8 membrane for multiplexed immunoassay of human interleukins

在线全文

学校读者我要写书评

暂无评论

Nano Research 2023年第2期16卷 2866-2874页

作者： Yu Lv Mingshi Deng Xuefeng Wang Xinghua Gao lingyan feng Wei Chen Chung-Chiun Liu Xinxin Li Yuan Zhang Materials Genome Institute Shanghai UniversityShanghai 200444China State Key Laboratory of Transducer Technology Shanghai Institute of Microsystem and Information TechnologyChinese Academy of SciencesShanghai 200050China Department of Emergency Tongji HospitalTongji University School of MedicineShanghai 200065China Department of Chemical and Biomolecular Engineering Case Western Reserve UniversityClevelandOH 44106

To address the challenge of highly sensitive and accurate detection of biomarkers in complex environments,a rational engineering strategy for designing electrochemical immunosensing platform is ***,we develop a microsensor chip through the combination of multiplexed electrodes and microfluidic channels for the parallel detection of human interleukins(IL-6 and IL-8).For the construction of an efficient sensing interface,the conductive silver nanowires(Ag NWs)wrapped with zeolitic imidazolate framework(ZIF-8)thin film(denoted as ZIF-8@Ag NWs)are prepared,and then employed for the multi-functionalization of *** immunodetection of ILs is based on the direct signal transduction ability of Ag NWs and specific interaction of periodically arranged Zn2+ions in ZIF-8 films with biomolecules,which offer the high assay sensitivity and good *** immunosensor chip achieves a wide detection range from pg/mL to ng/mL and possesses the ability to resist non-specific proteins adsorption in biological complex *** clinical serum samples assay verifies that the combination of IL-6 and IL-8 levels yields high diagnostic *** component analysis(PCA)reveals that 18 patient samples could be fully separated from healthy control *** low-cost,easily fabricated electrochemical immunosensing platform provides a rapid serum test for diagnosis and personalized therapy of inflammatory diseases,and can also be generalized to other immunoreaction-based biomarkers detections.

关键词： zeolitic imidazolate framework(ZIF) integrated nanostructure microsensor biomarker detection interleukins

RhIr@MoS2 nanohybrids based disposable microsensor for the point-of-care testing of NADH in real human serum

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2020年第8期31卷 2115-2118页

作者： Dongqing Ji Zi Ying Yuan Zhang Wei Chen Metini Janyasupab Xinghua Gao lingyan feng Weijia Wen Materials Genome Institute Shanghai UniversityShanghai 200444China State Key Laboratory of Transducer Technology Shanghai Institute of Microsystem and Information TechnologyChinese Academy of Sciences.Shanghai 200050China Department of Emergency Tongji HospitalTongji University School of MedicineShanghai 200065China Department of Electronics Engineering King Mongkut's Institute of Technology LadkrabangBangkok 10520Thailand

Dihydronicotinamide adenine dinucleotide(NADH)is an important enzyme in all living cells,which is found to be abnormally expressed in cancer *** it is redox-active,an electrochemical detection method would be suitable for monitoring its concentration in biological *** we present a strategy for specific determination of NADH in real human serum by using RhIr@MoS2 nanohybrids based *** implement the protocol,RhIr nanocrysrals are in-situ grown onto MoS2 interlayers forming a nanohybrid structure(RhIr@MoS2).After being locally deposited on an electrochemical microsensor,it could be used for the analysis of *** developed RhIr@MoS2 nanohybrids based microsensor possesses the ability for analyzing NADH at the applied potential of 0.07 V(much lower than most reported values).The detection limit is evaluated as low as 1 nmol/L even in bovine serum albumin(BSA)*** addition,the sampling analysis of human serum from cancer patients and health controls shows that the microsensor displays good diagnostic sensitivity and specificity,illustrating that this developed detection technique is a relatively accurate method for measuring NADH in biological *** proposed electrochemical microsensor assay also owns the benefits of convenience,disposable and easy processing,which make it a great possibility for future point-of-care cancer diagnosis.

关键词： MoS2 Nanohybrid Electrochemical microsensor Point-of-care(POC)test Cancer diagnosis

KIR2DL2/C1 is a Risk Factor for Chronic Infection and Associated with Non-response to PEG-IFN and RBV Combination Therapy in Hepatitis C Virus Genotype 1b Patients in China

在线全文

学校读者我要写书评

暂无评论

Virologica Sinica 2018年第4期33卷 369-372页

作者： Song Hu Fahu Yuan lingyan feng Fang Zheng Feili Gong Hanju Huang Binlian Sun Medical College Jianghan University Department of Immunology School of Basic MedicineTongji Medical College Huazhong University of Science and Technology Department of Pathogen Biology Tongji Medical CollegeHuazhong University of Science and Technology

Dear Editor,Natural killer(NK)cells are lymphocytes that play important roles in the host defense against hepatitis C virus(HCV)*** cell immunoglobulin-like receptors(KIRs)are a group of regulatory molecules expressed on NK cells and a subset of T cells(Parham 2005).Ligands for KIRs are human leukocyte antigen(HLA)class Ⅰ molecules,and HLA-C1 is a ligand for the

关键词：丙肝病毒风险因素联合治疗感染遗传型反应中国免疫球蛋白

在线全文

学校读者我要写书评

暂无评论

基于数字图书馆的高校文检课教学模式的研究

黑龙江科技信息 2011年第2期 187-188页

作者：冯菱燕天津医科大学图书馆天津300070

随着计算机技术、通信技术、网络技术的迅猛发展,数字图书馆已成为高校建设与发展的重要组成部分。而伴随着图书馆数字化建设程度的提高,计算机检索已成为主要检索方式。面对信息网络环境,高校文检课教学必须探索出一条适应数字环境和... 详细信息

随着计算机技术、通信技术、网络技术的迅猛发展,数字图书馆已成为高校建设与发展的重要组成部分。而伴随着图书馆数字化建设程度的提高,计算机检索已成为主要检索方式。面对信息网络环境,高校文检课教学必须探索出一条适应数字环境和网络环境的新路子以实现高校人才培养的总体目标。

关键词：数字图书馆图书馆数字化建设文检课教学

结合生涯教育开展近视防控的探索与实践——以江苏省苏州工业园区星洲小学为例

在线全文

学校读者我要写书评

暂无评论

中小学校长 2022年第1期 25-28页

作者：冯凌燕江苏省苏州工业园区星洲小学

健康的视力是学生生涯发展的重要保障。当前青少年近视呈现低龄化趋势,小学阶段是学生生涯发展的初期,近视防控工作尤为重要。江苏省苏州工业园区星洲小学通过"精准制定近视防控方案、精细实施近视防控措施、精彩收获近视防控成果"的系... 详细信息

健康的视力是学生生涯发展的重要保障。当前青少年近视呈现低龄化趋势,小学阶段是学生生涯发展的初期,近视防控工作尤为重要。江苏省苏州工业园区星洲小学通过"精准制定近视防控方案、精细实施近视防控措施、精彩收获近视防控成果"的系统推进,以"全动员、全达标、全时段、全过程、全融合、全督查"的系统落实,有效促进了近视防控工作的深入实施,收获了显著成效。

关键词：小学近视防控生涯教育 “三精六全”系统