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冠脉支架术后患者支架内再狭窄原因的回顾性研究

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冠脉支架术后患者支架内再狭窄原因的回顾性研究

作者： farhan Shaikh（王强）苏州大学

学位级别：硕士

目的：通过对冠脉支架植入术后复查造影患者的回顾性分析，研究引起支架内再狭窄的可能原因。方法：入选我院2009年至2010年期间所有复查造影的冠心病支架治疗患者73例（年龄67.90±8.83岁，男性59人，女性14人），将其分成支架内... 详细信息

目的：通过对冠脉支架植入术后复查造影患者的回顾性分析，研究引起支架内再狭窄的可能原因。方法：入选我院2009年至2010年期间所有复查造影的冠心病支架治疗患者73例（年龄67.90±8.83岁，男性59人，女性14人），将其分成支架内再狭窄组及无再狭窄组，分析两组间可能导致支架内再狭窄的因素间差异。结果：73名患者共植入177枚支架，其中有22枚支架发生再狭窄（支架内再狭窄定义为随访时造影提示支架内管腔内径损失≥50%）。分析两组基本临床资料特征及支架长度、直径，是否为药物涂层支架等因素;支架内再狭窄组及无再狭窄组在吸烟、2型糖尿病、支架长度、直径和药物/非药物支架方面有显著差异（P ＜0.05）。Cox比例风险回归模型显示仅支架长度（P=0.009）、直径（P=0.029）和药物/非药物支架（P=0.026）为冠心病介入患者发生ISR的预测因子结论：冠脉支架植入后发生再狭窄的主要原因为支架长度、直径及是否为药物支架。

关键词：冠心病冠脉介入术支架内再狭窄

Manipulation of SlMXl for enhanced carotenoids accumulation and drought resistance in tomato

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Science Bulletin 2016年第18期61卷 1413-1418页

作者： Mohamed Ewas Yanqiang Gao Shouchuang Wang Xianqing Liu Hongyan Zhang Elsayed M. E. Nishawy farhan Aii Raheel Shahzad Khurram Ziaf Hizar Subthain Cathie Martin Jie Luo National Key Laboratory of Crop Genetic Improvement andNational Center of Plant Gene Research (Wuhan) Huazhong Agricultural University Wuhan 430070 China College of Life Science and Technology Huazhong Agricultural University Wuhan 430070 China Key Laboratory of Horticultural Plant Biology Ministry of Education Huazhong Agricultural University Wuhan 430070China John Innes Centre Norwich Research Park Colney Norwich NR4 7UH UK

Plants are the ultimate source of nutrients in the human diet. To ensure adequate availability of high quality food for an increasing world population, traits including improved tolerance of stresses and nutrient levels need to be selected in crops, both individually and in combination. Here we report the identification of Sl MX1 encoding a MIXTA-like MYB transcription factor in tomato that simultaneously modulates drought resistance and metabolic processes through regulating key structural and regulatory genes of the corresponding pathways. Over-expression of Sl MX1 results in substantially increased drought tolerance and improved fruit quality, while knocking down Sl MX1 resulted in the opposite phenotypes. Our study indicates an effective way with multiple beneficial traits by genetic engineering of a single regulatory gene and can be a novel approach to breeding crops.

关键词：抗旱性类胡萝卜素番茄 MYB转录因子操纵积累果实品质世界人口

饲料中添加黄芪和杜仲提取物对鲫鱼生长性能、血液生化指标、抗氧化性能以及组织结构的影响

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饲料中添加黄芪和杜仲提取物对鲫鱼生长性能、血液生化指标、抗氧...

作者： farhan Aye Tahir 南京农业大学

学位级别：硕士

开展研究的目的,在于探究饲料中添加黄芪（Astragalus membranaceus,AM）和杜仲（Eucommia ulmoides,EU）叶提取物对鲫鱼的生长性能、机体抗氧化应激能力以及组织结构产生的影响。饲料中添加黄芪和杜仲叶提取物对鲫鱼生长性能、饲料利... 详细信息

开展研究的目的,在于探究饲料中添加黄芪（Astragalus membranaceus,AM）和杜仲（Eucommia ulmoides,EU）叶提取物对鲫鱼的生长性能、机体抗氧化应激能力以及组织结构产生的影响。饲料中添加黄芪和杜仲叶提取物对鲫鱼生长性能、饲料利用率和全鱼体成分的影响实验设置了六组等氮等能的饲料,分别为添加了 0.02%AM,0.1%EU,0.02%AM＆0.05%EU,0.02%AM＆0.1%EU（kg-1）以及 0.02%AM＆0.2%EU 的试验日粮。用六组饲料分别投喂养殖在循环水系统中的实验鱼（初始均重为10.01g±0.002g）,养殖周期为8周。养殖期间,每天人工投喂4次至表观饱食。养殖试验结束后发现,投喂0.02%AM＆0.05%EU,0.02%AM＆0.1%EU 以及 0.02%AM＆0.2%EU（kg-1）饲料组的鱼体重（FBW）、体重增长率（WGR）以及特定生长率（SGR）显著高于对照组、0.02%AM组以及0.1%EU组（P＜0.05）,尽管其中0.02%AM与0.02%AM＆0.1%EU组之间的这些指标并无显著差异（P＞0.05）。此外,处理组的饲料系数（FCR）与对照组无显著差异（P＞0.05）,但 0.02%AM＆0.05%EU 组的 FCR 显著低于 0.1%EU 组的（P＜0.05）。全鱼体成分结果来看,0.02%AM+0.05%EU组和0.02%AM+0.2%EU组水分含量显著低于对照组之外,其余所有组的全鱼水分含量均无显著差异（P＞0.05）,其他所有组之间均无显著差异。所有处理组鱼体粗蛋白水平与对照组无显著差异,除了处理组中的0.02%AM＆0.05%EU组显著高于0.02%AM组之外（P＜0.05）。不同日粮投喂实验对鱼体灰分含量并没有显著影响。0.2%AM组的粗脂肪含量显著低于0.02%AM＆0.2%EU组（P＜0.05）,但与对照组无显著差异。饲料中添加黄芪和杜仲叶提取物对鲫鱼血浆生化指标以及鱼体抗氧化应激能力的影响饲料中添加黄芪和杜仲叶提取物对鲫鱼血浆葡萄糖（GLU）、谷丙转氨酶（ALT）、谷草转氨酶（AST）、总蛋白（TP）、白蛋白（ALB）、总甘油三酯（TG）以及总胆固醇（TC）水平有显著影响。结果发现,投喂添加了 0.02%AM饲料的鱼体血糖水平显著低于对照组和其他处理组（P＜0.05）。0.02%AM＆0.2%EU组血浆ALT水平显著低于对照组和 0.02%AM＆0.1%EU 组（P＜0.05）,但与 0.02%AM、0.1%EU 和 0.02%AM＆0.05 EU%差异不显著（P＞0.05）。处理组血浆AST水平与对照组相比无显著差异,但是0.1%EU 组的 AST 水平显著高于 0.02%AM＆0.2%EU 组（P＜0.05）。0.02%AM＆0.05%EU组血浆TP和ALB水平最高,且显著高于对照组、0.02 AM%组和0.02%AM＆0.2%EU组（P＜0.05）。0.02%AM和0.02%AM＆0.2%EU组鱼体血浆TG和TC含量显著低于对照组及剩余处理组（P＜0.05）。在本研究中,饲料中添加黄芪和杜仲叶提取物同样对鱼体肝脏过氧化氢酶（CAT）、超氧化物歧化酶（SOD）和溶菌酶（LYSOZYME）产生显著影响,但对丙二醛（MDA）没有影响。所有实验组中,除0.02%AM＆0.2%EU饲料组的鱼体肝脏CAT活性显著高于对照组和0.02%AM组外（P＜0.05）,均与对照组无显著差异,且0.02%AM＆0.2%EU与剩余的其他处理组也无显著差异。摄食添加了 0.02%AM＆0.2%EU的饲料的鱼体肝脏SOD活性显著高于对照组、0.02%AM组以及0.02%AM＆0.1%EU组（P＜0.05）,但与剩余组无差异。溶菌酶活性在所有处理组中无显著差异,但0.02%AM＆0.05%EU和0.02%AM＆0.2%EU组的溶菌酶活性显著低于对照组（P＜0.05）。饲料中添加黄芪和杜仲叶提取物对鲫鱼肝脏和肠道组织结构的影响通过对肝脏和肠道组织切片进行HE染色观察其组织结构的变化。结果显示,与对照组、0.02%AM（Fig-4.1B）,0.02%AM＆0.05%EU（Fig-4.1D）以及 0.02%AM＆0.2%EU（Fig-4.1F）组不同的是,摄食添加了 0.1%EU（Fig-4.1C）、0.02%AM＆0.1%EU（Fig-4.1E）饲料组的肝脏细胞出现严重的水肿和细胞核固缩现象。与对照组相比,摄食0.02%AM（Fig-4.2B）,0.02%AM＆0.05%EU（Fig-4.2D）和 0.02%AM＆0.2%EU（Fig-4.2F）组的鱼肠道切片染色结果无显著差异。但是,添加了 0.1%EU（Fig-4.2C）和0.02%AM＆0.1%EU（Fig-4.2

关键词：黄芪杜仲生长性能抗氧化性组织学

Hypsometric Analysis of Wadi Mujib-Wala Watershed (Southern Jordan) Using Remote Sensing and GIS Techniques

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International Journal of Geosciences 2016年第2期7卷 158-176页

作者： Yahya farhan Adel Elgaziri Ibtisam Elmaji Intisar Ali Department of Geography University of Jordan Amman Jordan

Hypsometric analysis is considered an effective tool for understanding the stages of geomorphic evolution and geological development of river catchment, and for the delineation of erosional proneness of watershed. In the present study, twenty eight fourth order sub-basins of W. Mujib-Wala (Southern Jordan) were selected, and hypsometric analysis was carried out using 30 m ASTER DEM. Elevation-relief ratio method was employed to calculate the hypsometric integral values within GIS environment. The hypsometric integral values range from 0.71 to 0.88, whereas, the hypsometric curves exhibit remarkably upward convex shapes which indicate that all sub-basins and the W. Mujib-Wala watershed are at the youth-age stage of geomorphic development. Thus, they are of high susceptibility to erosion, incised channel erosion and mass movement activity. Marginal differences exist in mass removal from the watershed and the 28 sub-basins are attributed to variation in tectonic effect, lithology and rejuvenation processes. The relation between basin area and hypsometric integral was examined using regression analysis. Results reveal that negative and weak relationships dominate, where r2 ranges from 0.05 to 0.478 which confirm with other results reported elsewhere. Indirect assessment of erosion status based on hypsometric integral values was validated using estimated sediment yield information related to wadi Mujib and wadi Wala watersheds separately. The recorded sediment yields were in affirmation with high hypsometric integrals values, where higher values of hypsometric integrals and sediment yields occurred in the western part of the W. Mujib-Wala watershed. These findings would help in the construction of appropriate soil and water conservation measures across the watershed and its sub-basins to control soil erosion, to conserve water, and to reduce sediment discharge into the W. Mujib and W. Wala reservoirs.

关键词： Hypsometric Analysis Geomorphic Evolution RS GIS Hypsometric Integral Projected Profiles

Microstructure Evolution of Extruded Mg-6Gd Alloy Under 175 ℃ and 150 MPa

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Acta Metallurgica Sinica(English Letters) 2019年第2期32卷 245-252页

作者： Rong-Guang Li farhan Asghar Jing-Huai Zhang Guang-Yan Fu Qun Liu Bei-Tao Guo Yong-Mei Yu Shu-Guo Guo Yong Su Xue-Jiao Chen Lin Zong School of Mechanical Engineering Shenyang University of Chemical Technology Key Laboratory of Superlight Material and Surface Technology Ministry of Education College of Material Science and Chemical Engineering Harbin Engineering University

The tensile creep behavior of extruded Mg-6 Gd alloy,having the tensile yield strength of～ 110 MPa at 175 ℃,has been investigated under 175 ℃ and 150 MPa. In this study, the extruded Mg-6 Gd sample exhibits the total tensile strain of ～10.5% after the creep time of 1100 h,and the fast plastic strain of ～4.6% at the beginning of the creep test. The microstructure result suggests that the dislocation deformation is the main deformation mode during creep, and the grains with orientation close to(0001) II ED disappear after creep. The creep process containing a low creep strain has no effective promotion for the precipitation compared with the aging process without strain. The origination of creep crack is related to the formation of precipitate-free zone during creep. The work offers an important implication to research the microstructure evolution under an applied stress in a weak aging response Mg alloy.

关键词： Mg–Gd alloy Texture Creep Precipitates Crack

Regional Hypsometric Analysis of the Jordan Rift Drainage Basins (Jordan) Using Geographic Information System

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Open Journal of Geology 2016年第10期6卷 1312-1343页

作者： Yahya farhan Rami Mousa Arij Dagarah Durgham Shtaya Department of Geography University of Jordan Amman Jordan

This research is intended to assess the regional pattern of hypsometric curves (HCs) and hypsometric integrals (HIs) for the watersheds draining into the Jordan Rift (River Jordan, the Dead Sea, and Wadi Araba watersheds). Hypsometric analysis was performed on 22 drainage basins using ASTER DEM (30 m resolution) and GIS. The area-elevation ratio method was utilized to extract the hypsometric integral values within a GIS environment. A prominent variation exists in the HC shapes and HI values. The highest hypsometric values are found for the Dead Sea ( = 0.87) and River Jordan ( = 0.77) watersheds. Whereas the lowest values ( = 0.51) characterized Wadi Araba catchments, except Wadi Nukhaileh (lower Wadi Araba) which yields an HI value of 0.26. Seventeen HCs pertained to the River Jordan and the Dead Sea watersheds evince remarkably upward convex shapes indicating that such drainage basins are less eroded, and at the youth-stage of the geomorphic cycle of erosion. Catchments draining to Wadi Araba are of intermediate HI values (0.41 - 0.58) which are associated with a balance, or dynamic equilibrium between erosion and tectonic processes. Accordingly, they correspond to a late mature stage of geomorphic development. Additionally, Wadi Nukhaileh yields the lowest HI value (0.26) and is associated with highly eroded terrain of late mature geomorphic evolution, approaching an old stage therefore, with distorted concave upward curves. High HI values indicate that these watersheds have been subjected to tectonic uplift, down faulting of the Rift and intense rejuvenation. Differences in HI values can be attributed to disparity in tectonic uplift rate, base level heights, and mean heights of the River Jordan watersheds, the Dead Sea and Wadi Araba watersheds, and variation in lithology, which caused noticeable differences in rejuvenation processes, and channel incision. Regression analysis reveals that R2 values which represent the degree of control of driving par

关键词： Hypsometric Analysis Tectonic Activity GIS ASTER DEM Regression Analysis Jordan Rift

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使用深度学习的恶意网址检测

使用深度学习的恶意网址检测

作者： farhan Douksieh Abdi 山东科技大学

学位级别：硕士

In recent years,with the rapid development of the Internet,websites registering becomes extremely ***,the number and size of websites grow *** one hand,this has become an important part of our everyday life for information communication and knowledge *** helps to transact information timely,rapidly and *** the other hand,Malicious URLs host unsolicited content（spam,phishing,drive-by exploits,etc.）and lure unsuspecting users to become victims of scams（monetary loss,theft of private information,and malware installation）,and cause losses of billions of dollars every *** also provides living space for malicious *** detection is one of the most important technologies to prevent attacks from malicious ***,to detect such crimes systems should be fast and precise with the ability to detect new malicious ***,this detection is done mostly through the usage of ***,blacklists cannot be exhaustive,and lack the ability to detect newly generated malicious *** malicious URL becomes more complex,traditional URL detection methods seem to be unable to handle ***,it is particularly important to explore new,more reliable and accurate URL detection *** work is a high-precision,susceptible-learning and rapidly-reacting malicious URL detection system based on the deep learning *** whole work can be divided into three parts:the features selecting and processing,the training part and the classification *** the features selecting and processing,we get the word2vec feature,TF-IDF feature and content-based feature *** features have been used to train different machine learning and deep learning algorithms to detect and predicting URLs it is good or *** the results section,the performance evaluation of each of these algorithms have been *** results show that the algorithns Convolutional Neural Network（CNN）achieved the highest accuracy to compared wit

关键词：网络检测恶意网址深度学习

Amiodarone Improper Rapid Intravenous Injection Can Be Ended with Serious Complications and Even Death

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Journal of Pharmacy and Pharmacology 2015年第4期3卷 191-193页

作者： Hasan Ali farhan Israa Fadhil Yaseen Department of Cardiology Baghdad Teaching Hospital-Medical City Iraqi Board for Medical Specializations Scientific Councilof Cardiology Baghdad 00964 Iraq Department of Cardiology Baghdad Teaching Hospital-Medical City lraqi Board for Medical Specializations Scientific Councilof Clinical Pharmacy Baghdad 00964 Iraq

Amiodarone is one of the widely used antiarrhythmic drugs related to class III, used in the treatment of SVT (supraventricular) and ventricular arrhythmias. However, improper use of this drug such as pushing high concentration with rapid injection can increase the rate of adverse effects. The most common adverse effects associated with intravenous amiodarone are hypotension (16%), heart block or bradycardia (4.9%), and peripheral phlebitis (8-55%), this can be treated by diluting the drug and slowing the rate of infusion or discontinuing the drug. In addition, hypotension can be refractory and lead to a fatal outcome and death. Because phlebitis may occur, the drug should be given through a central line when possible. Some literatures refer to the administration of intravenous amiodarone in the treatment of arrhythmias such as in SVT, as "given over 10 minute" without focusing on the dilution and rate of infusion, therefore many residents give it with rapid direct intravenous injection without dilution and even during less than 10 minutes. From currently daily practice we are reporting two cases of amiodarone improper administration, first case "amiodarone-associated refractory hypotension" and second case "amiodarone-associated death".

关键词：药剂学药理学药学数学化学

Haplotype-based Genome-wide Association Study of Resistance Loci to Northern Leaf Blight in Maize

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Haplotype-based Genome-wide Association Study of Resistance ...