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Circuit model based design and analysis for a four-structure-switchable wireless power transfer system

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Science China(Technological Sciences) 2015年第3期58卷 534-544页

作者： fang xuelin LIU Hao LI GuiYang SHAO Qi LI HongYi State Key Laboratory of Robotics Shenyang Institute of Automation Chinese Academy of Sciences University of Chinese Academy of Sciences

The four-coil wireless power transfer(WPT)technology can effectively improve the transfer *** high efficiency,however,cannot be obtained along the whole transfer distance due to the phenomenon of frequency splitting in the over coupled *** at this limitation,this paper presents a switchable WPT system to improve the overall efficiency by changing the number of working *** switching conditions for the designed system are determined based on the analysis of the transfer efficiencies of four structures,which is deduced through modeling the equivalent *** simulation results well comply with the experimental results and both of them indicate that the switchable system can greatly improve the overall transfer efficiency along the whole transfer *** overall efficiency of the experimental system can reach above 70%at9.97 MHz without additional complexity,which is higher than any single structure system.

关键词： magnetic resonance coupling efficiency analysis structures switched wireless power transfer

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非对称式磁耦合谐振无线能量传输系统

信息与控制 2017年第2期46卷 243-247页

作者：方学林王重阳李洪谊中国科学院沈阳自动化研究所机器人学国家重点实验室辽宁沈阳110016 中国科学院大学北京100049

为解决无线能量传输系统中因接收端尺寸限制而导致传输效率下降,基于电路理论建立非对称式四线圈无线能量传输系统模型,并推导出系统效率表达式;分析系统主要参数对传输效率的影响,结果表明可通过提高发射线圈尺寸来补偿减小接收线圈组... 详细信息

为解决无线能量传输系统中因接收端尺寸限制而导致传输效率下降,基于电路理论建立非对称式四线圈无线能量传输系统模型,并推导出系统效率表达式;分析系统主要参数对传输效率的影响,结果表明可通过提高发射线圈尺寸来补偿减小接收线圈组尺寸所带来的效率损失,最后建立有限元仿真模型并搭建相关实验平台,实验数据、仿真数据与理论数据均具有较好的一致性,从而验证了本文理论分析,为后续非对称系统研究提供基础及实验数据.

关键词：磁耦合谐振非对称式传输效率无线能量传输(WPT)

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江苏先进制造业低碳集群供应链创新战略研究

物流科技 2022年第12期45卷 131-134页

作者：方雪琳南京财经大学红山学院江苏南京210003

为将中国的CO_(2)排放力争于2030年前达到峰值,在不足10年的时间内完成碳达峰值,对中国制造业而言,转型升级迫在眉睫。文章基于江苏先进制造业集群供应链,对其创新发展过程中所面对的战略环境进行分析,发现仍存在以下不足:例如产业集群... 详细信息

为将中国的CO_(2)排放力争于2030年前达到峰值,在不足10年的时间内完成碳达峰值,对中国制造业而言,转型升级迫在眉睫。文章基于江苏先进制造业集群供应链,对其创新发展过程中所面对的战略环境进行分析,发现仍存在以下不足:例如产业集群发展低度化;供应链内部集成度不足;供应链集群创新能力不足,缺乏核心竞争力;空间布局分散,区域发展不均衡以及集群供应链外部机制不完善等方面。因此,文章在把握全球供应链重构趋势和竞争要求的基础上,尤其是在碳达峰的目标下,对江苏先进制造业集群供应链创新的战略路径进行研究,以期促进实现传统制造业供应链的转型升级。

关键词：碳达峰集群供应链先进制造业

我国粮食物流发展研究(2018-2019年)

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粮食科技与经济 2019年第4期44卷 79-84页

作者：吴志华方雪琳刘念南京财经大学营销与物流管理学院/江苏一带一路研究院/江苏省现代粮食流通与安全协同创新中心

2018年是实施"十三五"规划承上启下的关键一年,也是粮食行业深化改革、转型发展的攻坚之年。2018年供给侧结构性改革进一步促进了粮食物流的高质量发展,粮食智慧物流与供应链创新得到进一步推进,"一带一路"粮食物流与供应链合作得到一... 详细信息

2018年是实施"十三五"规划承上启下的关键一年,也是粮食行业深化改革、转型发展的攻坚之年。2018年供给侧结构性改革进一步促进了粮食物流的高质量发展,粮食智慧物流与供应链创新得到进一步推进,"一带一路"粮食物流与供应链合作得到一定程度的推动。2019年如何科学与有效地解决稻谷库存过亿吨的难题日益迫切,"一带一路"粮食物流与供应链合作将得到高度重视与切实推进,粮食物流信息化建设将得到进一步提升,粮食安全与物流供应链风险防控将得到进一步的重视。

关键词：粮食物流回顾展望

Engineered Cancer Nanovaccines:A New Frontier in Cancer Therapy

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Nano-Micro Letters 2025年第2期17卷 134-168页

作者： Yijie Wang Congrui Liu Chao fang Qiuxia Peng Wen Qin Xuebing Yan Kun Zhang Central Laboratory and Department of Medical Ultrasound Sichuan Academy of Medical SciencesSichuan Provincial People’s HospitalSchool of MedicineUniversity of Electronic Science and Technology of ChinaNo.32West Second SectionFirst Ring RoadChengdu 610072People’s Republic of China Department of Stomatology and Central Laboratory School of MedicineShanghai Tenth People’s HospitalTongji UniversityNO.301 Yan‑Chang‑Zhong RoadShanghai 200072People’s Republic of China Jiangsu Provincial Innovation and Practice Base for Postdoctors Suining People’s HospitalAffiliated Hospital of Xuzhou Medical UniversityNo.2Bayi West RoadSuiningXu Zhou 221000Jiangsu ProvincePeople’s Republic of China

Vaccinations are essential for preventing and treating disease,especially cancer nanovaccines,which have gained considerable interest recently for their strong anti-tumor immune *** can prompt the immune system to generate antibodies and activate various immune cells,leading to a response against tumor tissues and reducing the negative effects and recurrence risks of traditional chemotherapy and *** enhance the flexibility and targeting of vaccines,nanovaccines utilize nanotechnology to encapsulate or carry antigens at the nanoscale level,enabling more controlled and precise drug delivery to enhance immune *** nanovaccines function by encapsulating tumor-specific antigens or tumor-associated antigens within *** small size of these nanomaterials allows for precise targeting of T cells,dendritic cells,or cancer cells,thereby eliciting a more potent anti-tumor *** this paper,we focus on the classification of carriers for cancer nanovaccines,the roles of different target cells,and clinically tested cancer nanovaccines,discussing strategies for effectively inducing cytotoxic T lymphocytes responses and optimizing antigen presentation,while also looking ahead to the translational challenges of moving from animal experiments to clinical trials.

关键词： Cancer nanovaccines Immunotherapy Nanobiotechnology Immune targets Signaling pathway

Inhibitory gamma-aminobutyric acidergic neurons in the anterior cingulate cortex participate in the comorbidity of pain and emotion

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Neural Regeneration Research 2025年第10期20卷 2838-2854页

作者： Lu Guan Mengting Qiu Na Li Zhengxiang Zhou Ru Ye Liyan Zhong Yashuang Xu Junhui Ren Yi Liang Xiaomei Shao Jianqiao fang Junfan fang Junying Du Department of Neurobiology and Acupuncture Research Third School of Clinical MedicineZhejiang Chinese Medical UniversityHangzhouZhejiang ProvinceChina Key Laboratory for Research of Acupuncture Treatment and Transformation of Emotional Diseases Third School of Clinical MedicineZhejiang Chinese Medical UniversityHangzhouZhejiang ProvinceChina Fuchun Community Health Service Center of Fuyang District HangzhouZhejiang ProvinceChina

Pain is often comorbid with emotional disorders such as anxiety and *** of the anterior cingulate cortex has been implicated in pain and pain-related negative emotions that arise from impairments in inhibitory gamma-aminobutyric acid *** review primarily aims to outline the main circuitry(including the input and output connectivity)of the anterior cingulate cortex and classification and functions of different gamma-aminobutyric acidergic neurons;it also describes the neurotransmitters/neuromodulators affecting these neurons,their intercommunication with other neurons,and their importance in mental comorbidities associated with chronic pain *** understanding on their role in pain-related mental comorbidities may facilitate the development of more effective treatments for these ***,the mechanisms that regulate gamma-aminobutyric acidergic systems remain *** is also unclear as to whether the mechanisms are presynaptic or *** exploration of the complexities of this system may reveal new pathways for research and drug development.

关键词： anterior cingulate cortex anxiety chronic pain circuit communication comorbidity depression gamma-aminobutyric acidergic neurons parvalbumin neurons synaptic transmission

肌肉定量MRI技术在脊髓性肌萎缩症中的研究进展

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临床神经病学杂志 2023年第4期36卷 305-307页

作者：黄杨陈嘉坤方雪琳李志勇深圳市儿童医院放射科 518000 汕头大学医学院深圳市龙岗区人民医院放射科

脊髓性肌萎缩症(SMA)是由脊髓前角α-运动神经元退行性变导致的常染色体隐性遗传病。定量MRI(qMRI)对SMA的病情评估及疗效监测有重要临床价值。本文就qMRI在SMA肌肉成像的研究进展进行综述。

关键词： MRI 肌肉脊髓性肌萎缩定量成像

High Fe‑Loading Single‑Atom Catalyst Boosts ROS Production by Density Effect for Efficient Antibacterial Therapy

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Nano-Micro Letters 2025年第2期17卷 187-203页

作者： Si Chen fang Huang Lijie Mao Zhimin Zhang Han Lin Qixin Yan Xiangyu Lu Jianlin Shi Department of Cardiology Shanghai Tenth People’s HospitalSchool of MedicineTongji UniversityShanghai 200092People’s Republic of China Shanghai Institute of Ceramics Chinese Academy of SciencesShanghai 200050People’s Republic of China Shanghai Frontiers Science Center of Nanocatalytic Medicine School of MedicineTongji UniversityShanghai 200092People’s Republic of China

The current single-atom catalysts(SACs)for medicine still suffer from the limited active site ***,we develop a synthetic method capable of increasing both the metal loading and mass-specific activity of SACs by exchanging zinc with *** constructed iron SACs(h^(3)-FNC)with a high metal loading of 6.27 wt%and an optimized adjacent Fe distance of~4 A exhibit excellent oxidase-like catalytic performance without significant activity decay after being stored for six months and promising antibacterial ***,a“density effect”has been found at a high-enough metal doping amount,at which individual active sites become close enough to interact with each other and alter the electronic structure,resulting in significantly boosted intrinsic activity of single-atomic iron sites in h^(3)-FNCs by 2.3 times compared to low-and medium-loading ***,the overall catalytic activity of h^(3)-FNC is highly improved,with mass activity and metal mass-specific activity that are,respectively,66 and 315 times higher than those of commercial Pt/*** addition,h^(3)-FNCs demonstrate efficiently enhanced capability in catalyzing oxygen reduction into superoxide anion(O_(2)·^(−))and glutathione(GSH)*** in vitro and in vivo assays demonstrate the superior antibacterial efficacy of h^(3)-FNCs in promoting wound *** work presents an intriguing activity-enhancement effect in catalysts and exhibits impressive therapeutic efficacy in combating bacterial infections.

关键词： Nanocatalytic medicine Single-atom catalysts Reactive oxygen species(ROS) High metal loading Oxidase catalysis

Duchenne型肌营养不良儿童大腿肌肉脂肪含量的MRS研究

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临床放射学杂志 2022年第12期41卷 2285-2289页

作者：方雪琳陈嘉坤路新国方佃刚孟宪磊曾洪武李志勇深圳市儿童医院放射科 518026 深圳市儿童医院神经内科 518026 汕头大学医学院 515041

目的探讨快速多回波T_(2)校正单体素波谱技术(HISTO-MRS)定量分析Duchenne型肌营养不良(DMD)患儿大腿肌肉脂肪含量的可行性及准确性,论证其诊断价值。方法纳入84例DMD患儿和36例年龄相匹配的健康男童,先行大腿T_(1)WI和多回波水脂分离技... 详细信息

目的探讨快速多回波T_(2)校正单体素波谱技术(HISTO-MRS)定量分析Duchenne型肌营养不良(DMD)患儿大腿肌肉脂肪含量的可行性及准确性,论证其诊断价值。方法纳入84例DMD患儿和36例年龄相匹配的健康男童,先行大腿T_(1)WI和多回波水脂分离技术(ME-Dixon)序列扫描,于右侧大收肌和股外侧肌行HISTO-MRS检查,自动得出HISTO-脂肪分数(FF)值。在ME-Dixon的FF图上手动勾画肌肉轮廓得到ME-Dixon-FF值。在轴位T_(1)WI图像上对大腿肌肉进行脂肪浸润程度半定量分级。采用Bland-Altman方法评估右侧大收肌两次HISTO-FF值的一致性,独立样本t检验比较DMD组和对照组HISTO-FF值的差异;最后分别评估DMD组HISTO-FF值与T_(1)WI脂肪浸润分级、ME-Dixon-FF值的相关性。结果大收肌HISTO-FF值95.2%数据点在95%一致性界限内,组内相关系数(ICC)为0.973。DMD组大收肌和股外侧肌的HISTO-FF值明显高于对照组(29.7%±22.0%vs.2.9%±1.9%,23.1%±20.0%vs.2.4%±2.0%,P均<0.001)。大收肌和股外侧肌的HISTO-FF值与T_(1)WI脂肪浸润程度分级高度正相关(r=0.793;r=0.881;P均<0.001),与ME-Dixon-FF值亦呈高度正相关(r=0.987;r=0.996;P均<0.001)。结论HISTO-MRS技术可快速准确测定DMD患儿大腿肌肉脂肪含量,对诊断疾病和评估脂肪浸润严重程度具有重要临床意义。

关键词：肌营养不良杜氏脂肪分数磁共振成像质子磁共振光谱