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The QTL analysis of seedling cold tolerance in a double haploid population derived from anther culture of indica/japonica

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Rice Science 1999年第2期 1-2页

作者： QIAN Qian~(1,2)) ZheN Dali~(2)) HUANG fang~(2)) he ping(1)) ZheNG Xianwu~(1)) CheN Ying~(1)) ZHU Lihuang~(1)) ~(1))Inst of Genetics,Academia Sinica,Beijing 100101 ~(2))CNRRI,Hangzhou 310006,China

A double haploid population,derived from anther eulture of F1of intersubspecies cross Zheyeqing 8/Jingxi 17（ZYQ 8/JX 17）was used to investigate the seedling eold tolerance （SCT） in growth cabinet.

关键词： QTL QTLs The QTL analysis of seedling cold tolerance in a double haploid population derived from anther culture of indica/japonica

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多元理性:家户制传统下的农户一家两制实践

华中师范大学学报（人文社会科学版） 2024年第4期63卷 14-28页

作者：周立方平中国人民大学农业与农村发展学院北京100872 广西民族大学管理学院广西南宁530006

怎样在实践中把握农户在食物生产上的一家两制?本文在家户制传统下提出多元理性框架,和单一理性的农业经济理论假定展开对话。本文认为,农户理性包含多元向度且相互联系:既依循差序责任,区分“自家人”和“外部人”,进行内外有别的食物... 详细信息

怎样在实践中把握农户在食物生产上的一家两制?本文在家户制传统下提出多元理性框架,和单一理性的农业经济理论假定展开对话。本文认为,农户理性包含多元向度且相互联系:既依循差序责任,区分“自家人”和“外部人”,进行内外有别的食物生产,“让自家人吃自家饭”,带来“个体自保”,也能进行推己及人的价值权衡,在场域约束与道义反思的互构中,将“外部人”视同为“自家人”,从而“让有条件的自家人吃上自家饭”,促进“社会共保”。基于东亚家户制传统的多元理性,与基于西方农业经济理论的单一经济理性假定的对话,有助于更新农民学研究的认识基础,构建基于中国实践的理论,发现能够促进食物体系可持续发展的小农路径。

关键词：多元理性一家两制家户制小农户差序责任

Breast cancer and rectal cancer associated with Lynch syndrome:A case report

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World Journal of Clinical Oncology 2024年第9期15卷 1215-1221页

作者： Pei-fang Qin Ling Yang Jun-ping Hu Jing-Yue Zhang Department of Laboratory Medicine The People Hospital of GuigangGuigang 537100Guangxi Zhuang Autonomous RegionChina

BACKGROUND The development mechanisms of Lynch syndrome(LS)-related breast cancer(BC)and rectal cancer are complex and variable,leading to personalized variations in diagnosis and treatment *** SUMMARY This paper presents a comprehensive review of clinical diagnosis and treatment data from a patient with LS-associated BC and rectal ***,screening data and management guidelines,as well as relevant literature on LS,are included in this *** study summarizes the molecular pathogenesis,clinicopathological features,and screening and management protocols for LS-associated BC and rectal *** Implementing early screening,prevention,and timely diagnosis and treatment measures is expected to reduce mitigate the incidence and mortality of LS-related BC and rectal cancer.

关键词： Lynch syndrome Breast cancer Rectal cancer Mismatch repair gene Case reports

Deciphering the mechanism of Liu Wei Di Huang Wan in treating premature ovarian failure:a comprehensive exploration through network pharmacology and molecular docking analysis

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Journal of Chinese Pharmaceutical Sciences 2024年第9期33卷 805-818页

作者： ping Shang Lin Liu Yi fang Chongqing health Center for Women and Children Women and Children's Hospital of Chongqing Medical UniversityChongqing 401147China

Premature ovarian failure(POF)is a prevalent gynecological disorder with significant implications for the physical and mental well-being of affected *** Wei Di Huang Wan(LWDHW),a Chinese herbal compound,has demonstrated efficacy in alleviating the effects of ***,the underlying mechanism of action of LWDHW remains *** study aimed to elucidate the potential molecular mechanism of LWDHW in treating POF using network pharmacology and molecular docking *** active ingredients of LWDHW were initially screened through the TCMSP *** the same time,the relevant target genes associated with POF were identified using databases such as Disgenet,TTD,Drugbank,Gene Cards,OMIM,and Pharm *** analysis was conducted using the R language,Cytoscape,and STRING to construct and analyze the traditional Chinese medicine(TCM)regulatory network and protein-protein interaction(PPI)network ***,GO and KEGG enrichment analyses were performed using the R ***,molecular docking was carried out between the protein receptors of the core genes and the corresponding small-molecule *** study revealed 49 components and 189 predicted targets(after de-duplication)of LWDHW,along with 4524 targets(after de-duplication)associated with *** comparative analysis,163 potential genes were identified as common targets of LWDHW and POF,participating in biological processes such as response to chemical substances,molecular function regulation,and signaling receptor *** biological pathways implicated included the MAPK signaling pathway,IL-17 signaling pathway,and HIF-1 signaling pathway,among *** docking results demonstrated a robust binding ability between the core genes of LWDHW and their corresponding *** conclusion,this comprehensive analysis provided insights into the potential molecular mechanisms of LWDHW in treating *** identified common targets and associated pathways contributed to

关键词： Network pharmacology Liu Wei Di Huang Wan Premature ovarian failure Molecular docking

IAPWS-IF97公式在调节级特性曲线分析中的应用

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热力透平 2015年第1期44卷 67-71页

作者：方和平梅政文中国长江动力集团有限公司武汉430074

介绍了在用Fortran语言编写的调节级特性计算程序中,直接调用由WASPCN软件提供的IAPWSIF97公式链接库,利用其函数来计算水和水蒸气的热力特性。通过对比结果发现,该方法能够有效地提高计算精度。

关键词：调节级特性计算链接库 IAPWS-IF97公式

Pathogenesis of primary biliary cholangitis

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Gastroenterology & hepatology Research 2024年第3期6卷 7-9页

作者： Yong-fang Yang Xiao-Hui Yang Rong-ping Ye Wei Zhai School of Acupuncture Moxibustion and Tuina Tianjin University of Traditional Chinese MedicineTianjin 301617China College of Integrated Chinese and Western Medicine Tianjin University of Traditional Chinese MedicineTianjin 301617China

Disease overview of primary biliary cholangitis(PBC).PBC is one of the main subgroups of chronic cholestatic liver *** 2015,the designation of PBC was changed from primary biliary cirrhosis to remove the“cirrhosis stigma”to more accurately reflect the disease and its natural course[1,2].PBC is a chronic cholestasis disease mediated by autoimmunity.

关键词： biliary cirrhosis cholangitis

What Controls the Distribution of Ore Veins in Quartz Vein-type Tungsten Deposits: Constrains from Fan-shaped Mineralization in SE China

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Journal of Earth Science 2024年

作者： Gui-Cong fang Deng-Hong Wang Fu-Qiang Yang Zhan-Xu Ni Chang-Shuai Huang ping Wang Meng Feng Zuo-Hai Feng Guangxi Key Laboratory of Hidden Metallic Ore Deposits Exploration， College of Earth Science， Guilin University of Technology Collaborative Innovation Center for Exploration of Nonferrous Metal Deposits and Efficient Utilization of Resources By the Province and Ministry，Guilin University of Technology Institute of Mineral Resources， Chinese Academy of Geological Sciences Guangxi Zhuang Autonomous Region Institute of Geophysical Exploration Geological Team No.271 of Guangxi Zhuang Autonomous Region China Nonferrous Metal Guilin Research Institute of Geology for Mineral Resources Co.， Ltd Guangdong Geologic Survey Institute

Quartz vein-type tungsten deposits are a common W deposit type. Their ore vein distribution was previously considered to be controlled by regional horizontal tectonic stress. In this paper， 14 tungsten deposits with fan-shaped mineralization in SE China are summarized， and the relations between their ore veins and granite and the ore-forming structural stress field are analyzed. These deposits have a post-magmatic hydrothermal genesis and involve the formation of two sets of veins with similar strike and opposite dips at the top of the ore-causative granite bodies， forming a vertical fan-shaped profile. Their ore veins were coeval with the underlying granite bodies， and generally extend along the long axis of the granite. In such fan-shaped ore formation， the stress is highly focused at the top of the granite and gradually weakens outward. The maximum principal stress (σ1) is perpendicular to the granite contact surface， and radiates outward from the pluton. Meanwhile， the minimum principal stress (σ3) forms an arc-shaped band parallel to the contact surface. Our findings， together with published numerical modeling indicate that the emplacement dynamics of granitic magma (rather than regional horizontal tectonic stress) are essential controls on the distribution of ore veins in quartz vein-type tungsten deposits.

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Quantifying peripapillary vessel density and retinal nerve fibre layer in type 1 diabetic children without clinically detectable retinopathy using OCTA

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International Journal of Ophthalmology(English edition) 2024年第2期17卷 278-281页

作者： Ling Chen Yun Feng Sha-Sha Zhang Yan-fang Liu ping Lin Xi’an Children’s Hospital Affiliated to Xi’an Jiaotong University Xi’an 710002Shaanxi ProvinceChina

AIM:To quantify changes in radial peripapillary capillary vessel density(ppVD)and the peripapillary retinal nerve fiber layer(pRNFL)in children with type 1 diabetes without clinical diabetic retinopathy by optical coherence tomography angiography(OCTA),providing a basis for early retinopathy in children with type 1 ***:This was a retrospective study.A total of 30 patients(3–14y)with type 1 diabetes without clinical diabetic retinopathy(NDR group)were included.A total of 30 age-matched healthy subjects were included as the normal control group(CON group).The HbA1c level in the last 3mo was measured once in the NDR *** pRNFL thickness and ppVD were automatically measured,and the mean pRNFL and ppVD were calculated in the nasal,inferior,temporal,and superior *** changes in ppVD and pRNFL in the two groups were ***:Compared with CON group,the nasal and superior ppVDs decreased in the NDR group(all Phe thickness of the nasal pRNFL decreased significantly(Phe inferior,temporal and superior pRNFLs slightly decreased but not significant in the NDR group(all P>0.05).Person and Spearman correlation analysis of ppVD and pRNFL thickness in each quadrant of the NDR group showed a positive correlation between nasal and superior(all P0.05).There was no significant correlation between the HbA1c level and ppVD and pRNFL in any quadrant(all P>0.05).There was no significant correlation between the course of diabetes mellitus and ppVD and pRNFL in any quadrant(all P>0.05).CONCLUSION:ppVD and pRNFL decrease in eyes of children with type 1 diabetes before clinically detectable retinopathy and OCTA is helpful for early monitoring.

关键词： diabetic retinopathy children peripapillary vessel density peripapillary retinal nerve fiber layer optical coherence tomography angiography

基于多智能体近端策略优化的多信道动态频谱接入

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电子学报 2024年第6期52卷 1824-1831页

作者：陈平平张旭谢肇鹏丘毓萍方毅福州大学先进制造学院福建晋江362251 福州大学物理与信息工程学院福建福州350108 广东工业大学信息工程学院广东广州510006

为了在多用户多信道通信场景中应用动态频谱接入(Dynamic Spectrum Access,DSA)技术提高通信效率,保证用户公平,本文基于多智能体近端策略优化(Multi-Agent Proximal Policy Optimization,MAPPO)提出了MAPPO-DSA算法.该算法首先针对单... 详细信息

为了在多用户多信道通信场景中应用动态频谱接入(Dynamic Spectrum Access,DSA)技术提高通信效率,保证用户公平,本文基于多智能体近端策略优化(Multi-Agent Proximal Policy Optimization,MAPPO)提出了MAPPO-DSA算法.该算法首先针对单信道接入在多个信道同时空闲时存在的频谱浪费问题,使用多信道接入作为解决方案.同时,多信道接入导致状态空间与动作空间指数增长,计算成本高,学习难度大.为此本文引入MAPPO深度强化学习(Deep Reinforcement Learning,DRL)算法,在复杂环境中高效学习和优化接入策略.通过设计优化MAPPO中观测及奖励等强化学习要素和共享网络参数来保证用户公平.最后,在不同场景下的实验结果表明,所提出的MAPPO-DSA能够学习到近似最优的接入策略,部分场景中的网络吞吐量逼近理论上限,显著优于现有算法,且有效保证用户公平.

关键词：动态频谱接入深度强化学习多智能体近端优化多信道接入