检索结果-南通市图书馆

EXPRESSION OF A TELOMERASE-ASSOCIATED GENE IN NORMAL, ATROPHIC ,AND TUMOROUS TESTES

Chinese Medical Sciences Journal 2005年第3期20卷 217-220页

作者： fang Mei bo Zhang Zhi-wei Tang Lin Hou Department of Pathology Health Science Center Peking University Beijing 100083

Objective To evaluate the expression of telomerase transcriptional elements-interacting factor （TEIF） in human testis under different status and its relation with human telomerase reverse transcriptase （hTERT） expression. Methods Specific antisera against TEIF were generated by immunization of rabbits with purified recombinated partial TEIF. Samples were assigned to three groups according to their pathological types, including 16 normal testes, 8 atrophic testes, and 6 testicular seminomas. They were subjected to immunohistochemical staining of TEIF and hTERT. Results from both TEIF and hTERT were analyzed semi-quantitatively and compared. The expressions of TEIF and hTERT were detected in all samples of normal, atrophic testes, and seminomas. No differences of TEIF expressions among these three groups were observed （P 〉 0.05）. On the contrary, the expressions of hTERT were significantly lower in atrophic testes compared with those of normal testes and seminomas （both P 〈 0.05）. Nevertheless, co-expressions of TEIF with hTERT were revealed to be in normal and malignant cases （P 〈 0.05） but not in atrophic testes, which generally presented TEIF expression. The cellular distributions of both proteins were similar and mainly in spermatocytes and some Sertoli cells, while were all negative in the interstitial cells and other stromal cells. Conclusion The uniform expressions of TEIF in all these specimens suggest that it may be a marker of testis and its related diseases. The strong expression of hTERT in normal testes and testicular seminomas comparing with the low expression in atrophic testes may suggest a role for telomerase in maintaining proliferation of germ cells.

关键词： telomerase transcriptional elements-interacting factor human telomerase reverse transcriptase immunohistochemistry testis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Refractive index sensor based on high-order surface plasmon resonance in gold nanofilm coated photonic crystal fiber

引用

Chinese Physics B 2019年第9期28卷 212-219页

作者： Zhen-Kai Fan Shao-bo fang Shu-Guang Li Zhi-Yi Wei School of Information Science and Engineering Hebei University of Science and TechnologyShijiazhuang 050018China State Key Laboratory of Metastable Materials Science and Technology and Key Laboratory of Microstructural Material Physics of Hebei ProvinceSchool of ScienceYanshan UniversityQinhuangdao 066004China Institute of Physics Chinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China

We propose a novel kind of wide-range refractive index optical sensor based on photonic crystal fiber(PCF) covered with nano-ring gold *** refractive index sensing performance of the PCF sensor is analyzed and simulated by the finite element method(FEM).The refractive index liquid is infiltrated into the cladding air hole of the *** comparing the sensing performance of two kinds of photonic crystal fiber structures, a wide range and high sensitivity structure is *** surface plasmon resonance(SPR) excitation material is chose as gold, and large gold nanorings are embedded around the first cladding air hole of the *** higher order surface plasmon modes are generated in this designed optical fiber *** resonance coupling between the fundamental mode and the 5 th order surface plasmon polariton(SPP)modes is excited when the phase matching condition is ***, the 3 rd loss peaks appear obvious red-shift with the increase of the analyte refractive index, which shows a remarkable polynomial fitting *** fitnesses of two structures are 0.99 and 0.98, *** the range of refractive indices is from 1.40 to 1.43, the two kinds of sensors have high linear sensitivities of 1604 nm/RIU and 3978 nm/RIU, respectively.

关键词： surface plasmon resonance photonic crystal fiber sensor

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A PFM-based Global Convergence Visual Servo Path Planner

引用

自动化学报 2008年第10期34卷 1250-1256页

作者： ZHANG Xue-bo fang Yong-Chun MA bo-Jun Institute of Robotics and Information Automatic System NankaiUniversity Tianjin 300071 P.R. China

作为计划方法的一条古典本地路径，因为它的简洁和优雅，潜在的地方法(PFM ) 在机器人学地里广泛地被使用。然而，当产生一条路径让一个机器人列在后面时，这个方法的一个主要缺点是本地最小的存在。在这份报纸，我们在场由使用 PFM 方... 详细信息

作为计划方法的一条古典本地路径，因为它的简洁和优雅，潜在的地方法(PFM ) 在机器人学地里广泛地被使用。然而，当产生一条路径让一个机器人列在后面时，这个方法的一个主要缺点是本地最小的存在。在这份报纸，我们在场由使用 PFM 方法在看法(FOV ) 的照相机地以内保留特征为视觉伺服计划途径的一条路径。严密分析然后被介绍证明计划方法的构造路径的全球稳定性。而且，怎么获得的问题一更好三维(3D ) 照相机路径也广泛地被学习。模拟结果被提供验证建议路径规划者的表演。

关键词：自动化系统设计方案过程控制方法机器人

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

米粉稻早季与晚季种植品质差异研究

引用

作物学报 2024年第2期50卷 451-463页

作者：肖正午胡丽琴黎星解嘉鑫廖成静康玉灵胡玉萍张珂骞方升亮曹放波陈佳娜黄敏作物生理与分子生物学教育部重点实验室/湖南农业大学湖南长沙410128 衡阳市农业科学院湖南衡阳421101

为探明不同种植季节气候条件对米粉稻米粉蒸煮品质的影响,于2020—2022年在湖南浏阳开展大田试验,以5个米粉稻品种(广陆矮4号、中嘉早17、湘早籼24号、中早39、株两优729)为材料,比较米粉稻早季与晚季种植米粉蒸煮品质和稻米品质的差异... 详细信息

为探明不同种植季节气候条件对米粉稻米粉蒸煮品质的影响,于2020—2022年在湖南浏阳开展大田试验,以5个米粉稻品种(广陆矮4号、中嘉早17、湘早籼24号、中早39、株两优729)为材料,比较米粉稻早季与晚季种植米粉蒸煮品质和稻米品质的差异。结果表明,米粉稻品种在晚季种植时,灌浆期平均温度和平均辐射量比在早季种植分别降低18.7%和12.7%。米粉稻在晚季种植时,米粉损失率比在早季种植降低7.4%;米粉断条率和吸水率早晚季间差异不显著。与早季种植相比,米粉稻在晚季种植时稻米RVA谱特征值中峰值黏度、热浆黏度、崩解值、最终黏度、回复值和糊化温度分别下降25.8%、22.9%、34.3%、19.7%、14.2%和2.0%,而消减值和峰值时间分别上升11.8%和2.3%。相关性分析表明,灌浆期平均温度与稻米峰值黏度、热浆黏度、崩解值、最终黏度、回复值和糊化温度呈显著正相关,与消减值呈显著负相关;灌浆期平均辐射量与峰值黏度、热浆黏度、最终黏度呈显著正相关,与消减值呈显著负相关;米粉蒸煮损失率与最终黏度、糊化温度和峰值时间呈显著正相关。由此可见,米粉稻在晚季种植有助于米粉蒸煮品质提高。米粉稻RVA谱特征值中最终黏度和糊化温度是影响米粉损失率的关键指标。

关键词：米粉稻直链淀粉含量 RVA 米粉蒸煮品质温度辐射

来源：

维普期刊数据库

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Stability Analysis of Stochastic Swarm Systems

引用

Wuhan University Journal of Natural Sciences 2007年第3期12卷 506-510页

作者： YANG bo fang Huajing Department of Control Science and Engineering Huazhong University of Science and Technology Wuhan 430074 Hubei China

In this paper, we present a model of stochastic swarm system and prove the stability of this kind of systems. We establish the stable aggregating behavior for the group using a coordination control scheme. This individual-based control scheme is a combination of attractive and repulsive interactions among the individuals in the group, which ensures the cohesion of the group and collision avoidance among the individuals. The dynamics of each individual depends on the relative positions between the individuals and the influences of the random disturbances. Under the influences of the noises, this position-based control strategy still generates the stable aggregating behavior harmoniously for the group and the self-organized swarm pattern is formed.

关键词： stochastic swarm systems swarm pattern stochastic differential equations Lyapunov stability theory

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Photorheologically reversible micelle composed of polymerizable cationic surfactant and 4-phenylazo benzoic acid

引用

Chinese Journal of Chemical Engineering 2016年第2期24卷 289-292页

作者： Jie Chen bo fang Hao Jin Licheng Yu Meng Tian Kejing Li Leiping Jin Mo Yang Shanghai Key Laboratory of Multiphase Materials Chemical Engineering Lab of Chemical Engineering RheologyResearch Center of Chemical EngineeringEast China University of Science and Technology

A photorheologically reversible micelle composed of polymerizable cationic surfactant n-cetyl dimethylallyl am- monium chloride （CDAAC） and trans-4-phenylazo benzoic acid （trans-ACA） was prepared. The effects of molar ratio of CDAAC/trans-ACA, time of UV and visible light irradiation and temperature on the rheological properties of micellar system were investigated. The results show that before UV irradiation the system with an optimum CDAAC/trans-ACA molar ratio of 1.4 forms viscoelastic micelles at 45 ℃. After 365 nm UV irradiation, the viscos- ities of micelle systems with different concentrations at fixed molar ratio of 1.4 are decreased by 85%-95%. The CDAAC/trans-ACA （14 mmol. L- 1/10 mmol. L- 1 ） micelle system exhibits shear thinning property and its viscos- ity is decreased obviously with the increases of UV irradiation time less than I h. The rheological process during LIV irradiation for CDAAC/trans-ACA （14 mmol- L- 1/10 mmol. L 1） micelle proves that viscosity, elastic modulus G＇ and viscous modulus G＂ will reduce quickly with the UV light. Furthermore, the micelle system after 1 h UV- irradiation is able to revert to its initial high viscosity with 460 nm visible light irradiation for 4 h, and the micelle can be cycled between low and high viscosity states by repetitive UV and visible light irradiations. The LIV-Vis spectra of CDAAC/trans-ACA micelle indicate that its photosensitive theological properties are related closely to photoisomerization of trans-ACA to c/s-ACA.

关键词： Photorheological micelle Polymerizable cationic surfactant4-Phenylazo benzoic acid Rheological properties

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Inhibition of microRNA-29b suppresses oxidative stress and reduces apoptosis in ischemic stroke

引用

Neural Regeneration Research 2022年第2期17卷 433-439页

作者： Yao-Hua Ma Wen-Jing Deng Zhi-Yi Luo Jing Jing Peng-Wei Pan Yao-Bing Yao Yan-bo fang Jun-fang Teng Neurological Intensive Care Unit the First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan ProvinceChina

MicroRNAs(miRNAs) regulate protein expression by antagonizing the translation of mRNAs and are effective regulators of normal nervous system development, function, and disease. Micro RNA-29 b(mi R-29 b) plays a broad and critical role in brain homeostasis. In this study, we tested the function of mi R-29 b in animal and cell models by inhibiting mi R-29 b expression. Mouse models of middle cerebral artery occlusion were established using the modified Zea-Longa suture method. Prior to modeling, 50 nmol/kg mi R-29 b antagomir was injected via the tail vein. Mi R-29 b expression was found to be abnormally increased in ischemic brain tissue. The inhibition of mi R-29 b expression decreased the neurological function score and reduced the cerebral infarction volume and cell apoptosis. In addition, the inhibition of mi R-29 b significantly decreased the malondialdehyde level, increased superoxide dismutase activity, and Bcl-2 expression, and inhibited Bax and Caspase3 expression. PC12 cells were treated with glutamate for 12 hours to establish in vitro cell models of ischemic stroke and then treated with the mi R-29 antagomir for 48 hours. The results revealed that mi R-29 b inhibition in PC12 cells increased Bcl-2 expression and inhibited cell apoptosis and oxidative damage. These findings suggest that the inhibition of mi R-29 b inhibits oxidative stress and cell apoptosis in ischemic stroke, producing therapeutic effects in ischemic stroke. This study was approved by the Laboratory Animal Care and Use Committee of the First Affiliated Hospital of Zhengzhou University(approval No. 201709276 S) on September 27, 2017.

关键词： Akt apoptosis cerebral artery occlusion ischemic stroke malondialdehyde microRNA-29b oxidative stress PI3K superoxide dismutase

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The roles of microRNAs in spinal cord ischemia-reperfusion injury

引用

Neural Regeneration Research 2022年第12期17卷 2593-2599页

作者： Feng-Shou Chen Xiang-Yi Tong bo fang Dan Wang Xiao-Qian Li Zai-Li Zhang Department of Anesthesiology the First Hospital of China Medical UniversityShenyangLiaoning ProvinceChina

Spinal cord ischemia/reperfusion injury is a devastating medical disorder with poor prognosis that is associated with several pathophysiological ***,multiple stimuli can trigger SCII,so the underlying mechanism of this pathology has not yet been fully ***(miRNAs)are a class of non-coding RNAs that mediate a variety of nervous system diseases and regulate numerous physiological functions,including apoptosis,autophagy,inflammation,and blood-spinal cord barrier *** expression profiles are known to be altered after spinal cord ischemia/reperfusion ***,gaining a better understanding of the significant roles that miRNAs play in spinal cord ischemia/reperfusion injury could help develop potential preventive and therapeutic strategies for spinal cord ischemia/reperfusion *** review summarizes the current state of our knowledge about the relationship between miRNAs and spinal cord ischemia/reperfusion injury,as well as potential miRNAs that could be targeted to treat spinal cord ischemia/reperfusion injury.

关键词： apoptosis autophagy blood-spinal cord barrier inflammation microRNAs pathophysiology review spinal cord ischemia-reperfusion injury

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

CLUTTER SUPPRESSION METHOD IN GPR USING PARTICLE CLUSTERING

引用

Journal of Electronics(China) 2009年第5期26卷 584-587页

作者： Lu Cewu Liu Xiaojun Zhao bo fang Guangyou The Institute of Electronics Chinese Academy of Sciences Beijing 100091 China

In this paper, a novel clutter suppression method in Ground Penetrating Radar (GPR) is proposed. Time segments of hill are represented by their corresponding particle in B-scan. Those particles in B-scan are clustered to represent reflectors (such as buried targets, air-soil interface). The clusters of buried target have a particle sequence with single peak. Therefore, if the particles donot belong to the cluster of buried target, time segment they represent will be suppressed. Experimental results and simulation are provided to demonstrate that the new algorithm outperforms existing approaches.

关键词： Ground Penetrating Radar (GPR) Clutter suppression Clustering

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Study on Fractionated Total body Irradiation before Hematopoietic Stem Cell Transplantation

引用

Chinese Journal of Clinical Oncology 2009年第1期6卷 47-50页

作者： Tong fang bo Liu Hong Gao Department of Radiation Oncology BeijingShijitan Hospital Beijing 100038 China.

OBJECTIVE To observe the dose and the complicationsfrom total body irradiation before hematopoietic stem *** This study involved 312 patients with total bodyirradiation before hematopoietic stem cell transplantation. Theywere entered into the treated research from May 1999 to October2005. All patients had received the irradiation from ^(60)Co of anabsorbed dose rate of (5.2 ± 1.13) cGy/min. The total dose of TBIwas 7～12 Gy, 1 f/d × 2 d. A high-dose rate group (≥10 Gy) included139 cases and a low-dose rate group (body irradiation at a doserate of 5 cGy/min, with a total dose of 7～12 Gy, 1 f/d × 2 d , withthe lung receiving under 7.5 Gy is a safe and effective pretreatmentfor hematopoietic stem cell transplantation.

关键词： hematopoietic stem cell transplantation pretreatment total body irradiation absorbed dose rate.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：