检索结果-南通市图书馆

Chinese Journal of Structural Chemistry 2015年第6期34卷 917-924页

作者： LIU Wen-Qian ZHOU Shi-Lei fan ming-zhu PAN Zhi-Quan CHEN Yun-Feng School of Chemistry and Environmental Engineering Wuhan Institute of Technology

The novel dinuclear copper complex [Cu2（H20）2（DMF）2（L）2] （1, H2L = 5-phenyl- 2H-1,2,3-triazole-4-carboxylic acid, DMF = N,N-dimethyl-formamide） has been synthesized and characterized by X-ray single-crystal diffraction. The compound crystallizes in triclinic system, space group P1 with a = 9.591, b = 10.508, c = 15.515A,β = 75.11°, V= 1446.2 A3, Z= 2, Mr = 683.62, Dc = 1.570 g/cm3, μ = 1.531 mm^-1, F（000） = 700, the final R = 0.0404 and wR = 0.1130 for 5327 observed reflections with I 〉 2σ（I）. In each unit of the complex, two Cu2＋ ions coordinated with two triazole ligands to form a dimeric [5,6,5] tricyclic structure. The central Cu atom is five-coordinated, and each copper atom shows a square pyramidal geometry. The crystal structure is stabilized by the inversion-related O-H…O hydrogen bond and C-H…O hydrogen bonding interactions to form a layer structure. Fluorescent spectra show an obvious quenching of fluorescence compared with free 1,2,3-triazole ligand. The results of agarose gel electrophoresis indicate that this complex can cleave the plasmid supercoiled DNA within shorter time in the 50-folds excess of ascorbate under physiological conditions, providing a new example in the research for artificial metal nucleic acid enzyme.

关键词： 1,2,3-triazole copper complex crystal structure fluorescent property DNA cleavage activity

在线全文

学校读者我要写书评

暂无评论

无铁心永磁同步直线电机推力谐波分析与消除

中国电机工程学报 2017年第7期37卷 2101-2109页

作者：支凡张鸣朱煜李鑫摩擦学国家重点实验室(清华大学) 北京市海淀区100084

直线电机的推力波动较大,限制其在超精密领域的应用。推力中的谐波是无铁心永磁同步直线电机推力波动的主要原因之一,消除推力中的部分谐波可以有效降低推力波动。该文建立了无铁心永磁体同步直线电机推力谐波的解析模型,揭示了结构参... 详细信息

直线电机的推力波动较大,限制其在超精密领域的应用。推力中的谐波是无铁心永磁同步直线电机推力波动的主要原因之一,消除推力中的部分谐波可以有效降低推力波动。该文建立了无铁心永磁体同步直线电机推力谐波的解析模型,揭示了结构参数与推力波动间的关系,并提出了低推力波动直线电机的设计准则。将设计准则应用于一类直线电机的优化设计中,提出了消除推力中特定阶次谐波的结构参数设计方法。设计结果与有限元仿真结果和实验结果进行比对,验证了解析模型的准确性和设计方法的有效性。

关键词：无铁心永磁同步直线电机推力波动谐波麦克斯韦应力张量方法

Clinical results of combined palliative procedures for cyanotic congenital heart defects with intractable hypoplasia of pulmonary arteries

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2013年第9期126卷 1678-1682页

作者： fan Xiang-ming zhu Yao-bin SU Jun-wu ZHANG Jing LI Zhi-qiang XU Yao-qiang LI Xiao-feng LIU Ying-long Department of Pediatric Heart Center Department of Children Heart Center Beijing Anzhen Hospital Capital Medical University Beijing 100029 China

Background Congenital heart defects with intractable hypoplasia of the pulmonary arteries without intercourse or with intercourse stenosis is unsuitable for surgical correction or regular palliative procedures. We reported our experience with combined palliative procedures for congenital heart defects with intractable hypoplasia pulmonary arteries. Methods From 2001 to 2012, a total of 41 patients with cyanotic congenital heart defects and intractable hypoplasia of the pulmonary arteries underwent surgical procedures. From among them, 31 patients had pulmonary atresia with ventricular septal defect （VSD） and the other 10 cases had complicated congenital heart defects with pulmonary stenosis. Different kinds of palliative procedures were performed according to the morphology of the right and left pulmonary arteries in every patient. If the pulmonary artery was well developed, a Glenn procedure was performed. A modified Blalock-Taussig shunt or modified Waterston shunt was performed if pulmonary arteries were hypoplastic. If the pulmonary arteries were severely hypoplastic, a Melbourne shunt was performed. Systemic pulmonary artery shunts were performed bilaterally in 25 cases. A systemic-pulmonary shunt was performed on one side and a Glenn procedure was performed contralaterally in 16 cases. Major aortopulmonary collateral arteries were unifocalized in six cases, ligated in two cases and interventionally embolized in two cases. There was one early death because of cardiac arrest and the hospital mortality was 2.4%. Results Five patients suffered from postoperative low cardiac output syndrome, three had perfusion of the lungs, and two pulmonary infections. Systemic pulmonary shunts were repeated after the original operation in three cases due to the occlusion of conduits. The mean follow-up time was 25 months. The pre- and the post-operation left pulmonary indices were （8.13±3.68） vs. （14.9±6.21） mm2/m2. The pre- and post-operation right pulmonary indices were （12.7±

关键词： congenital heart disease hypoplasia of pulmonary artery palliation

异质性股东引入与企业创新质量——来自中国A股上市公司的经验证据

在线全文

学校读者我要写书评

暂无评论

山西财经大学学报 2023年第5期45卷 99-112页

作者：范明珠王京徐璟娜中国海洋大学管理学院山东青岛266100

立足于中国混合所有制改革的现实情境,基于2008—2021年度沪深两市A股上市企业的财务数据,考察异质性股东引入对企业创新质量的影响。研究发现,异质性股东引入对企业创新质量具有积极作用,股权多元化、股权制衡程度和异质性股东委派董... 详细信息

立足于中国混合所有制改革的现实情境,基于2008—2021年度沪深两市A股上市企业的财务数据,考察异质性股东引入对企业创新质量的影响。研究发现,异质性股东引入对企业创新质量具有积极作用,股权多元化、股权制衡程度和异质性股东委派董事与企业创新质量正相关。进一步研究发现,异质性股东引入通过促进企业获取资源支持和提升创新意愿提高自身创新质量;在知识产权保护力度和产品市场竞争较强的企业中,异质性股东引入对创新质量的促进作用更为显著;异质性股东引入对创新质量的正向作用能够促进企业价值增值。

关键词：创新质量异质性股东引入政府补助创新意愿外部环境

在线全文

学校读者我要写书评

暂无评论

论领导者在组织中的角色定位

商丘职业技术学院学报 2008年第4期7卷 16-18页

作者：范明珠郑州大学公共管理学院河南郑州450052

领导者有六种主要角色。以这六种主要角色归类为平台,结合领导者在管理中的实践可知:领导者是学习教育和实践经验的产物。领导者必须通过不断加强学习,积累和掌握理论知识,积极了解相关领域动态,努力进行领导开发,在实践中总结提高,才... 详细信息

领导者有六种主要角色。以这六种主要角色归类为平台,结合领导者在管理中的实践可知:领导者是学习教育和实践经验的产物。领导者必须通过不断加强学习,积累和掌握理论知识,积极了解相关领域动态,努力进行领导开发,在实践中总结提高,才能胜任组织中的领导者角色。

关键词：角色定位影响力领导者追随者情境

Dynamic Regulation of Hydrogen Bonding Networks and Solvation Structures for Synergistic Solar‑Thermal Desalination of Seawater and Catalytic Degradation of Organic Pollutants

在线全文

学校读者我要写书评

暂无评论

Nano-Micro Letters 2025年第2期17卷 548-565页

作者： ming‑Yuan Yu Jing Wu Guang Yin fan‑Zhen Jiao Zhong‑Zhen Yu Jin Qu Beijing Key Laboratory of Advanced Functional Polymer Composites Beijing University of Chemical TechnologyBeijing 100029People’s Republic of China State Key Laboratory of Organic‑Inorganic Composites College of Materials Science and EngineeringBeijing University of Chemical TechnologyBeijing 100029People’s Republic of China

Although solar steam generation strategy is efficient in desalinating seawater,it is still challenging to achieve continuous solar-thermal desalination of seawater and catalytic degradation of organic ***,dynamic regulations of hydrogen bonding networks and solvation structures are realized by designing an asymmetric bilayer membrane consisting of a bacterial cellulose/carbon nanotube/Co_(2)(OH)_(2)CO_(3)nanorod top layer and a bacterial cellulose/Co_(2)(OH)_(2)CO_(3)nanorod(BCH)bottom ***,the hydrogen bonding networks inside the membrane can be tuned by the rich surface–OH groups of the bacterial cellulose and Co_(2)(OH)_(2)CO_(3)as well as the ions and radicals in situ generated during the catalysis ***,both SO_(4)^(2−)and HSO_(5)−can regulate the solvation structure of Na^(+)and be adsorbed more preferentially on the evaporation surface than Cl^(−),thus hindering the de-solvation of the solvated Na^(+)and subsequent nucleation/growth of ***,the heat generated by the solar-thermal energy conversion can accelerate the reaction kinetics and enhance the catalytic degradation *** work provides a flow-bed water purification system with an asymmetric solar-thermal and catalytic membrane for synergistic solar thermal desalination of seawater/brine and catalytic degradation of organic pollutants.

关键词： Solar steam generation Seawater desalination Catalytic degradation Bacterial cellulose Cobalt hydroxycarbonate nanorods

在线全文

学校读者我要写书评

暂无评论

新一轮全国煤层气资源评价方法与结果

天然气工业 2009年第11期29卷 130-132页

作者：刘成林朱杰车长波杨虎林樊明珠中国石油大学油气资源与探测国家重点实验室国土资源部油气资源战略研究中心中国石化石油勘探开发研究院

新一轮的全国煤层气资源评价是迄今为止评价规模最大、范围最广、资源系列最全的一次,其成果已经得到了广泛应用。为此,详细介绍了新一轮全国煤层气资源评价采用的方法,并与我国历次煤层气资源评价进行了对比。新一轮全国煤层气资源评... 详细信息

新一轮的全国煤层气资源评价是迄今为止评价规模最大、范围最广、资源系列最全的一次,其成果已经得到了广泛应用。为此,详细介绍了新一轮全国煤层气资源评价采用的方法,并与我国历次煤层气资源评价进行了对比。新一轮全国煤层气资源评价采用了以体积法为主的评价方法体系,以煤层含气量、可采系数、煤层气资源类别评价标准等为关键评价参数,系统评价了全国42个主要含煤层气盆地(群)、121个含气区带的煤层气资源。评价结果表明:全国埋深2000m以浅煤层气地质资源量为36.81×1012m3,可采资源量为10.87×1012m3;煤层气资源集中分布在鄂尔多斯、沁水、准噶尔等大型盆地,在层系、深度和地理环境的分布上具有很强的不均衡性,资源品质较好,以Ⅰ、Ⅱ类为主。

关键词：新一轮煤层气资源评价方法评价参数分布盆地

Cpne5,a new Ca2+ dependent phospholipids binding protein,works as a negative factor in the neuronal migration

在线全文

学校读者我要写书评

暂无评论

Cpne5,a new Ca2+ dependent phospholipids binding protein,wor...

前列腺素和白三烯在内毒素所致肺动脉高压中的意义

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Xuefeng DING,Yan WU,Fei WANG,Yongqi ZHAO,Ying WU,Shuhong LIU,Wenhong fan,Lingling zhu,ming fan Department of Brain Protection & Plasticity Research,Beijing Institute of Basic Medical Sciences,Beijing 100850, China

Cpne5 is a new Ca dependent phospholipids binding *** Previous studies on Cpne5 showed that it was mainly expressed in the ventricular zone(VZ).Further investigation demonstrated that Cpne5 was expressed both in the neural progenitor cells and newborn neurons in *** indicates that Cpne5 might play an important role in neurogenesis of the ventricular *** confirm our presumption,we established in utero electroporation model. With the shRNA expression vector targeting Cpne5 mRNA,we knocked down Cpne5 expression in the neurocytes in VZ at embryonic day 16(E16d),and the human GFP-CPNE5 expression vector was transfected into the neurocytes in VZ at embryonic day 16,and then Postnatal mouse brain at 3 days after birth(P3d,6d after electroporation) were fixed with 4%PFA and then sliced at 30μm *** analysis on slices showed that inhibiting Cpne5 expression can remarkably increase the number of neuron migrating to the cortex surface,and overexpressed CPNE5 protein can remarkably decrease the number of neuron migrating to the cortex *** indicates that Cpne5 may work as a negative factor in the neuronal migration.

关键词： Cpne5 neurodevelopment in utero electroporation neuronal migration

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

同济医科大学学报 1991年第4期20卷 225-228页

作者：范明朱振汉王迪浔同济医科大学基础医学部病理生理学教研室

给狗一次注射大肠杆菌内毒素5μg/kg,引起肺动脉压和肺血管阻力显著增加,肺动脉嵌压无明显变化。动脉血浆血栓素β_z和6-酮-PGF1α水平及白三烯含量均明显升高。环氧合酶抑制剂消炎痛可缓解肺动脉压力升高;脂氧合酶抑制剂乙胺嗪,阻断白... 详细信息

给狗一次注射大肠杆菌内毒素5μg/kg,引起肺动脉压和肺血管阻力显著增加,肺动脉嵌压无明显变化。动脉血浆血栓素β_z和6-酮-PGF1α水平及白三烯含量均明显升高。环氧合酶抑制剂消炎痛可缓解肺动脉压力升高;脂氧合酶抑制剂乙胺嗪,阻断白三烯生成及部分抑制血栓素B_2的增加,可以阻止肺动脉高压形成。提示:内毒素所致肺动脉高压与血栓素A_2和白三烯有关。

关键词：肺动脉高压前列腺素内毒素

在线全文

学校读者我要写书评

暂无评论

晚期肿瘤患者鞘内镇痛与预防感染的措施

中华医院感染学杂志 2014年第12期24卷 2980-2981,2984页

作者：张菊明魏琴孟丽琴范明珠杜建龙桐乡市第一人民医院肿瘤内科浙江桐乡314500 桐乡市第一人民医院疼痛科浙江桐乡314500

目的观察晚期肿瘤患者在应用鞘内镇痛的临床效果及安全性,同时为治疗中感染的预防措施提供参考依据。方法对2011年2月-2012年2月收治的28例晚期肿瘤患者采用硬膜外置管自控镇痛泵鞘内注射吗啡,观察其临床效果、并发症的发生及预防感染措... 详细信息

目的观察晚期肿瘤患者在应用鞘内镇痛的临床效果及安全性,同时为治疗中感染的预防措施提供参考依据。方法对2011年2月-2012年2月收治的28例晚期肿瘤患者采用硬膜外置管自控镇痛泵鞘内注射吗啡,观察其临床效果、并发症的发生及预防感染措施,并对恶性肿瘤患者病原菌及耐药性进行统计分析,数据采用SPSS13.0软件进行处理。结果 28例患者治疗后24、72h、1周、1个月视觉模拟疼痛(VAS)评分、睡眠质量测定(QS)评分均优于治疗前,差异有统计学意义(P<0.05);治疗后24hVAS、QS评分分别为(4.12±0.21)、(2.44±0.25)分,均优于治疗后72h、1周、1月VAS、QS评分,差异有统计学意义(P<0.05);28例患者在吗啡鞘内镇痛输注过程中,未发生硬膜外腔感染;治疗后1个月便秘、尿潴留、恶心呕吐、瘙痒、嗜睡发生率较治疗前减少,差异有统计学意义(P<0.05)。结论对于晚期肿瘤患者应用鞘内注射吗啡镇痛技术同时加强对感染的控制,临床效果好且治疗安全,是一种治疗晚期肿瘤疼痛的有效方法。

关键词：晚期肿瘤患者鞘内镇痛感染