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软科学 2016年第8期30卷 42-46页

作者：范莉莉江玉国西南交通大学经济管理学院成都610031 西南科技大学经济管理学院四川绵阳621010

通过对钢铁企业现状的描述和经典文献的研究,构建了钢铁企业的低碳竞争力评价指标体系;提出了熵值法的评价模型,在搜集全国重点钢铁企业相关数据的基础上,运用该模型计算了各指标的信息熵、效用值、权重;通过实证研究得出了样本企业的... 详细信息

通过对钢铁企业现状的描述和经典文献的研究,构建了钢铁企业的低碳竞争力评价指标体系;提出了熵值法的评价模型,在搜集全国重点钢铁企业相关数据的基础上,运用该模型计算了各指标的信息熵、效用值、权重;通过实证研究得出了样本企业的低碳竞争力水平。

关键词：低碳经济低碳竞争力熵值法指标体系

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铁路运输高新技术装备社会效益评价的研究

系统工程学报 2005年第1期20卷 38-42页

作者：范莉莉王晓刚西南交通大学经济管理学院四川成都610031

针对铁路运输特点,从可持续发展、资源利用、对社会的贡献、对行业的贡献、安全以及人文环境六方面研究了铁路运输装备高新技术产品社会效益的评价指标体系,采用熵权法建立评价模型,定量与定性相结合,对我国生产的铁路运输装备高新技术... 详细信息

针对铁路运输特点,从可持续发展、资源利用、对社会的贡献、对行业的贡献、安全以及人文环境六方面研究了铁路运输装备高新技术产品社会效益的评价指标体系,采用熵权法建立评价模型,定量与定性相结合,对我国生产的铁路运输装备高新技术产品———"蓝箭"动车组、"大白鲨"动车组以及韶山9型电力机车进行了综合评价.评价结果表明"蓝箭"动车组的社会效益明显好于其他另外两个产品.

关键词：铁路运输装备高新技术产品品质指标评价

信息不对称条件下竞价排名机制的信息匹配效率研究

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运筹与管理 2022年第2期31卷 119-125页

作者：蔡祖国刘璐范莉莉西南交通大学经济管理学院四川成都610031

本文聚焦消费者依赖搜索引擎平台的关键词检索实施购买商品行为的现象,尝试将消费者购买策略引入搜索平台竞价排名机制,构造内嵌搜索引擎平台、销售商、消费者三方主体的博弈模型,考察在互联网信息不对称条件下,竞价排名机制的信息匹配... 详细信息

本文聚焦消费者依赖搜索引擎平台的关键词检索实施购买商品行为的现象,尝试将消费者购买策略引入搜索平台竞价排名机制,构造内嵌搜索引擎平台、销售商、消费者三方主体的博弈模型,考察在互联网信息不对称条件下,竞价排名机制的信息匹配效率,阐释产品质量信号改善竞价排名机制信息匹配效率的理论机理。研究发现,在信息不对称及无产品质量信号机制的条件下,竞价排名均衡结果完全不能匹配消费者的购买策略,致使消费者福利因销售商逆向选择而遭受双重损失;植入产品质量信号后,搜索引擎平台能够通过识别销售商自带的产品质量信号,提高竞价排名机制的均衡结果与消费者购买策略的匹配度,进而部分地改善竞价排名机制的信息匹配效率。

关键词：竞价排名信息不对称搜索引擎平台信息匹配效率

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酸枣仁-合欢花对抑郁模型大鼠行为学及内质网应激PERK/ATF4/CHOP通路的影响

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中国实验方剂学杂志 2021年第7期27卷 66-72页

作者：曹智怡李玲范丽丽王明杰郭超峰施学丽广西中医药大学南宁530200 广西中医药大学第一附属医院南宁530023

目的:研究酸枣仁-合欢花对抑郁模型大鼠行为学及内质网应激蛋白激酶R样内质网激酶(PERK)/活化的转录因子4(ATF4)/CCAAT/增强子结合蛋白同源蛋白(CHOP)通路的影响,并探讨其抗抑郁作用的机制。方法:将雄性SD大鼠按随机数字表法分为正常组... 详细信息

目的:研究酸枣仁-合欢花对抑郁模型大鼠行为学及内质网应激蛋白激酶R样内质网激酶(PERK)/活化的转录因子4(ATF4)/CCAAT/增强子结合蛋白同源蛋白(CHOP)通路的影响,并探讨其抗抑郁作用的机制。方法:将雄性SD大鼠按随机数字表法分为正常组,模型组,盐酸文拉法辛组(0.008 g·kg^(-1)),酸枣仁-合欢花高、中、低剂量组(16,8,4 g·kg^(-1)),每组15只。除正常组外,其余5组采用慢性不可预见性温和应激(CUMS)结合孤养的方式建立抑郁模型,造模的同时给予正常组和模型组大鼠等体积的蒸馏水灌胃,各给药组大鼠予相应剂量的药物灌胃,连续21 d。于实验的第1天和第21天进行旷场实验和糖水消耗实验观察各组大鼠行为学变化;采用透射电镜观察大鼠海马神经元超微结构变化;采用原位末端标记(TUNEL)法检测大鼠海马区神经元凋亡情况;采用蛋白免疫印迹法(Western blot)技术检测大鼠海马组织PERK,CHOP,B淋巴细胞瘤-2相关X蛋白(Bax),半胱氨酸天冬氨酸蛋白酶-3(Caspase-3)蛋白表达情况。结果:与正常组比较,模型组大鼠旷场实验得分、糖水消耗率显著下降(P<0.01);与模型组大鼠比较,酸枣仁-合欢花各剂量组及盐酸文拉法辛组大鼠旷场实验得分、糖水消耗率均显著升高(P<0.01);透射电镜显示,与正常组比较,模型组大鼠海马区神经元损伤明显,与模型组比较,酸枣仁-合欢花各剂量组及盐酸文拉法辛组大鼠海马区神经元损伤减轻;TUNEL显示,与正常组比较,模型组大鼠海马区神经元凋亡数量增加(P<0.01),与模型组比较,酸枣仁-合欢花各剂量组及盐酸文拉法辛组大鼠海马区神经元凋亡数量减少(P<0.01)。Western blot结果显示,与正常组大鼠比较,模型组大鼠海马PERK,CHOP,Bax,Caspase-3蛋白表达水平显著升高(P<0.01);与模型组大鼠比较,盐酸文拉法辛组和酸枣仁-合欢花各剂量组大鼠海马PERK,CHOP,Bax,Caspase-3蛋白表达水平均降低(P<0.05,P<0.01)。结论:酸枣仁-合欢花可能通过调节内质网应激PERK/ATF4/CHOP通路而发挥抗抑郁作用。

关键词：酸枣仁-合欢花抑郁症内质网应激蛋白激酶R样内质网激酶(PERK) CCAAT/增强子结合蛋白同源蛋白(CHOP)

Changes of chymase,angiotensin converting enzyme and angiotensin Ⅱ type 1 receptor expressions in the hamster heart during the development of heart failure

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Chinese Medical Journal 2005年第22期118卷 1886-1892页

作者： CHEN Peng-min LENG Xi-gang fan li-li MA Jun WANG Ya-fang CHEN Lan-ying Department of Biochemistry Institute of Clinical Medicine China-Japan Friendship Hospital Beijing 100029 Department of Biochemistry Fuwai Hospital and CardiovascularInstitute Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100037 China Department of Biochemistry Institute of Biomedical EngineeringChinese Academy of Medical Sciences and Peking Union Medical College Tianjin 300192 China Department of Pharmacology Institute of Materia Medica Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100050 China

Background little is known about the role of dual angiotensin Ⅱ forming pathways during heart failure. In the present study, the changes of chymase and angiotensin converting enzyme （ACE） expressions in the failing hearts of hamsters were analysed. Methods Heart failure was induced by ligation of left anterior descending branch of the coronary artery. Chymase, ACE and angiotensin Ⅱ type 1 receptor （AT1R） mRNA levels were analysed by reverse transcription polymerase chain reaction （RT-PCR）. The activities of chymase and ACE were determined by radioimmunoassay （RIA）. Myocardial collagen fibre analysis was performed under optical microscope. Results Left ventricular systolic pressure （LVSP） and maximum left ventricular developed pressure increase rate （ dp/dtmax, mmHg/s） gradually moved lower at 2, 3,4 and 8 weeks after operation. On the other hand, left ventricular end-diastolic pressure （LVEDP） increased gradually after operation. Compared with the control group （3.55±0. 06, 4.79±0.70）, the heart weight/body weight ratio in operation group had increased significantly at 4 weeks and 8 weeks （4. 28±0. 43, 6. 17±0.73）（P 〈0. 01 ）. Collagen staining showed that the quantity of myocardial collagen fibre increased significantly in the operation group. RT-PCR showed that the chymase mRNA level in the operation group was consistently greater than that in the control group. ATIR mRNA level was also increased significantly at 3 weeks and 4 weeks, both being 1.3 times that of the control group （ P〈0.01 ）, whereas ACE mRNA level was not changed. Higher activity of chymase was detected in operation group, being 4, 8, 13 and 19 times that of the control group at 2, 3, 4 and 8 weeks （P〈0.01 ）, respectively. ACE activity was also significantly higher at the same time, being 7, 10, 10 and 3.5 times that of the control（P〈0.01）. Angiotensin Ⅱ （Ang Ⅱ） level in operation group increased significantly, being 2.5, 2.7, 3.5 and 2 times that of the control group at 2, 3, 4 and 8 weeks, res

关键词： chymase angiotensin converting enzyme angiotensin Ⅱ· heart failure ·angiotensin Ⅱ type 1 receptor

Polybenzimidazolium-reinforced polyimide separators to inhibit dendrites for high-security lithium-ion batteries

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Science China Chemistry 2025年

作者： Guohua Sun Jiaqi Cui Qingsong Zhang Yisong Zhou Xinluo li Yingying Zhang Zhanao Zhang Xin Zhang Jiantao fan Pengpeng li lianlong Hou Nanjun Chen Hebei Key Laboratory of Flexible Functional Materials School of Materials Science and Engineering Hebei University of Science and Technology State Key Laboratory of Organic-Inorganic Composites Beijing University of Chemical Technology Academy for Advanced Interdisciplinary Studies Southern University of Science and Technology State Key Laboratory of Physical Chemistry of Solid Surfaces College of Chemistry and Chemical Engineering Xiamen University

lithium dendrite formation poses a significant safety hazard in lithium-ion batteries（liBs）, severely impeding their widespread adoption and further technological advancements. Here, we present a novel quaternized polybenzimidazolium（q-PBI） to armor polyimide（PI） nanofiber separator（q-PBI@PI）, in which the q-PBI containing lithiophilicity and anionphilicity sites serves as the multifunctional nano-layers to suppress the li dendrite and reinforce the mechanical properties of PI nanofiber ***, the q-PBI@PI separator displays an unprecedented mechanical strength of 82.8 MPa, significantly outperforming previously reported PI nanofiber membranes（typically below 50.0 MPa）. Besides, we demonstrate that the q-PBI@PI separator simultaneously possesses low nucleation overpotential（59 mV） and exceptional average coulombic efficiency due to the suppression of li dendrite. Importantly, q-PBI@PI-based li||li battery enables a stable li plating-stripping at 1.0 m A cm-2for600 h. Attributing to these exceptional merits, the armored PI separator-based liBs display remarkable specific capability and capacity retention. The density function theory calculations reveal that q-PBI is conducive to the desolvation of li+and can immobilize li+and PF6-ions near affinity sites of PI nanofibers for inhibiting the formation of li dendrites. Our work paves a new avenue for the design of next-generation high-performing separators in liBs.

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注塑制品残余应力的研究进展

高分子通报 2017年第1期 66-70页

作者：李廷健朱辉樊利阳立张杰四川大学高分子科学与工程学院成都610065

由于实际工艺条件往往与理想值存在一定偏差,制品在成形后通常会存在一些难以避免的缺陷,而残余应力正是最为常见的一种。注塑制品的残余应力是在注塑成形过程中,外界约束去除后,仍存在于塑件内部的应力,在后期使用过程中容易引起塑件... 详细信息

由于实际工艺条件往往与理想值存在一定偏差,制品在成形后通常会存在一些难以避免的缺陷,而残余应力正是最为常见的一种。注塑制品的残余应力是在注塑成形过程中,外界约束去除后,仍存在于塑件内部的应力,在后期使用过程中容易引起塑件的翘曲、变形、乃至断裂破损,多数情况下对制品不利。因此,在塑料制品设计时应充分考虑到残余应力的影响。本文较为全面地介绍了注塑制品残余应力的产生、检测、减小残余应力的措施及残余应力的计算机模拟等内容。

关键词：残余应力残余应力检测方法 MOLDFLOW

Development and Preliminary Application of Double Antibody Sandwich EliSA for Detection of Swine Vesicular Disease Virus

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Animal Husbandry and Feed Science 2011年第4期3卷 24-26,42页

作者： WU Guo-hua YAN Xin-min ZHAO Zhi-xun CUI li-fan li Jian ZHU Hai-xia ZHU Cai-zhu ZHANG Qiang State Key Laboratory of Veterinary Etiological Biology National Foot and Mouth Disease Reference Laboratory Lanzhou Veterinary Research In-stitute Chinese Academy of Agricultural Sciences Lanzhou 730046 China

[Objective] The aim of this study was to develop an indirect sandwich EUSA method for detection of swine vesicular disease virus （SVDV）. [Method] High titer serum against SVDV was prepared respectively by inoculated rabbits and guinea pigs with purified virus. To develop an indirect sandwich EliSA, the optimum concentrations of capture antibody, detection antibody, enzyme conjugate and standard antigen were determined using block titration, and positive threshold value was also determined. The specificity, sensitivity and repeatability of the developed IEliSA were evaluated using cross-reaction test, comparison test and intra-assay repeated test. In addition, standard samples and clinical samples were detected by this method. [ Result] The best working conditions of the developed EliSA are as follows： capture antibody, 1：400; detection antibody, 1 ： 200; enzyme conjugate, 1 ： 8 000; and standard antigen, 1 ： 4. The positive threshold value was found to be 0.20. For the detection by the developed EUSA, no cross-reaction with foot and mouth disease was observed. The developed EliSA had close sensitivity with EliSA recommended by the World Organisation for Animal Health （OIE） but had sensitivity 2 -4 times higher than that of reverse indirect hernagglutination test. In addition, the developed method also had good reproducibility, and the detection results of standard samples were in line withtheir own background. All the 36 clinical samples were negative in the developed EliSA. [ Conclusion] The developed indirect sandwich EliSA can be used for diagnosis of swine vesicular disease.

关键词： Swine vesicular disease virus Sandwich EliSA Diagnosis

Factors Affecting the Extraction of Polysaccharide from Phellinus igniarius Fruit Bodies

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食用菌学报 2006年第4期 53-55页

作者： GUO Shu-fan, ZHANG Hui-li, li Yu, XIN Ru, liU Hong-sheng College of life Science, liaoning University, Shenyang, liaoning 110036, China

Optimum conditions for extracting polysaccharide from Phellinus igniarius fruit bodies were studied using monofactorial and orthogonal testing. Optimal conditions for hot water extraction of polysaccharide were: 1∶30 sample∶water ratio, 3 h lixiviation time, 90 ℃ lixiviation temperature, and 80% final ethanol concentration. Polysaccharide yields obtained from P. igniarius fruit bodies using ultrasound were higher than those achieved using the hot water lixiviation method. The optimal treatment time for ultrasonic extraction was 50 min, and the yield was 4.65%.

关键词： Extraction conditions Fruit body polysaccharide Phellinus igniarius

薄壁囊腔型肺癌与薄壁空洞性肺结核的MDCT表现鉴别诊断研究

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临床放射学杂志 2017年第1期36卷 44-49页

作者：望云范丽李清楚刘士远第二军医大学附属长征医院影像医学与核医学科上海200003

目的对比分析薄壁囊腔型肺癌与薄壁空洞性肺结核的CT表现特点。方法回顾性分析经病理或临床证实的30例薄壁囊腔型肺癌和29例薄壁空洞性肺结核患者的一般资料及MDCT征象。采用t检验、Mann-Whitney U检验、χ~2检验及Fisher确切概率法进... 详细信息

目的对比分析薄壁囊腔型肺癌与薄壁空洞性肺结核的CT表现特点。方法回顾性分析经病理或临床证实的30例薄壁囊腔型肺癌和29例薄壁空洞性肺结核患者的一般资料及MDCT征象。采用t检验、Mann-Whitney U检验、χ~2检验及Fisher确切概率法进行统计分析。结果肺癌组与结核组的患者性别差异无统计学意义(P>0.05),肺癌组平均发病年龄高于结核组[(60.07±10.26)岁vs(43.41±17.21)岁,P0.05)。肺癌组的分叶征、短毛刺、清楚光整的界面、多囊、内部分隔及血管穿行、磨玻璃征的比例高于结核组,差异有统计学意义(P0.05)。结论薄壁囊腔型肺癌与薄壁空洞性肺结核的CT征象不同,分叶征、毛刺征、尖角、瘤肺界面、内壁光整度、腔内结构、磨玻璃征、卫星灶有助于鉴别诊断。

关键词：周围型肺癌含气囊腔肺结核空洞 CT