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Redistribution of Pb, Zn and Cu Fractions in Tailing Soils Treated with Different Extractants

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Pedosphere 2006年第3期16卷 312-318页

作者： liU Yun-Guo WANG Xian-Hai ZENG Guang-Ming li Xin ZHOU Chun-Hua fan Ting li Yong-li YUAN Xin-Zhong Department of Environmental Science and Engineering Hunan University Changsha 410082 （China） Institute of Applied Ecology Chinese Academy of Sciences Shenyang 110016 （China） Graduate School of Chinese Academy of Sciences Beijing 100039 （China）

The efficiency of EDTA, HNO3 and CaCl2 as extractants to remove Pb, Zn and Cu from tailing soils without varying soil pH was investigated with distributions of Pb, Zn and Cu being determined before and after extraction using the sequential extraction procedure of the optimized European Community Bureau of Reference (BCR). Results indicated that EDTA and HNO3 were both effective extracting *** extractability of extractants for Pb and Zn was in the order EDTA > HNO3 > CaCl2, while for Cu it was HNO3 > EDTA > CaCl2. After EDTA extraction, the proportion of Pb, Zn and Cu in the four fractions varied greatly, which was related to the strong extraction and complexation ability. Before and after extraction with HNO3 and CaCl2, the percentages of Pb, Zn and Cu in the reducible, oxidizable and residual fractions changed little compared to the acid-extractable fraction. The lability of metal in the soil and the kinds of extractants were the factors controlling the effects of metal extraction.

关键词： BCR extraction fraction heavy metals redistribution

Increase of peripheral Th17 lymphocytes during acute cellular rejection in liver transplant recipients

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Hepatobiliary & Pancreatic Diseases International 2012年第6期11卷 606-611页

作者： Hua fan, li-Xin li, Dong-Dong Han, Jian-Tao Kou, Ping li, Qiang He Department of Hepatobiliary Surgery, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China Department of Hepatobiliary Surgery Beijing Chaoyang Hospital Capital Medical University Beijing 100020 China

BACKGROUND: Although many human inflammatory and autoimmune diseases were previously considered to be mediated by T helper type 1 (Th1) cells, the recently described Th17 cells play dominant roles in several of these diseases. We and others speculated that allograft rejection after organ transplantation may also involve Th17 cells. Episodes of acute rejection occur in 30% of liver transplants. This study aimed to determine the frequency of circulating Th17 cells in patients who had received liver transplants for benign end-stage liver disease and to identify any association between acute rejection episodes and levels of Th17 cells in the peripheral blood. METHODS: A prospective study compared Th17 cells from 76 consecutive benign end-stage liver disease patients who had undergone orthotopic liver transplantation from 2007 to 2011 with those from 20 age-matched healthy individuals. Peripheral blood samples were collected at different time points within one year after transplant. Blood samples and liver biopsies were also collected at the diagnosis of acute rejection. Percentages of circulating CD4+ IL-17+ cells were measured by flow cytometry The transplant patients were classified into two groups: a rejection group consisting of 17 patients who had an episode of acute rejection, and a non-rejection group comprising the remaining 59 patients with no acute rejection episodes Percentages of circulating Th17 cells were compared between the two groups and controls. RESULTS: The levels of circulating CD4+ IL-17+ T cells in the rejection group were higher during acute rejection than those in the non-rejection group (2.56±0.43% versus 1.79±0.44% Pliver transplant recipients.

关键词： liver transplantation Th17 cells acute cellular rejection transplant immunology

From Perspective of Hippocampal Plasticity:Function of Antidepressant Chinese Medicine Xiaoyaosan

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Chinese Journal of Integrative Medicine 2024年第8期30卷 747-758页

作者： ZHANG Wu-jing GUO Ze-xuan WANG Yi-di fanG Shao-yi WAN Chun-miao YU Xiao-long GUO Xiao-fang CHEN Yue-yue ZHOU Xuan HUANG Jun-qing li Xiao-juan CHEN Jia-xu fan li-li Guangzhou Key Laboratory of Formula-Pattern of Traditional Chinese Medicine School of Traditional Chinese MedicineJinan UniversityGuangzhou510632China

The hippocampus is one of the most commonly studied brain regions in the context of *** volume of the hippocampus is significantly reduced in patients with depression,which severely disrupts hippocampal ***,antidepressant therapies that target hippocampal neuroplasticity have not been identified as *** medicine(CM)can slow the progression of depression,potentially by modulating hippocampal ***(XYS)is a CM formula that has been clinically used for the treatment of *** is known to protect Gan(liver)and Pi(Spleen)function,and may exert its antidepressant effects by regulating hippocampal *** this review,we have summarized the association between depression and aberrant hippocampal ***,we have discussed the researches published in the last 30 years on the effects of XYS on hippocampal neuroplasticity in order to elucidate the possible mechanisms underlying its therapeutic action against *** results of this review can aid future research on XYS for the treatment of depression.

关键词： depression hippocampal neuroplasticity Xiaoyaosan Chinese medicine

Defect Engineering:Can it Mitigate Strong Coulomb Effect of Mg^(2+)in Cathode Materials for Rechargeable Magnesium Batteries?

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Nano-Micro Letters 2025年第1期17卷 135-159页

作者： Zhengqing fan Ruimin li Xin Zhang Wanyu Zhao Zhenghui Pan Xiaowei Yang School of Chemistry and Chemical Engineering Shanghai Jiao Tong UniversityShanghai 200240People’s Republic of China School of Chemistry and Chemical Engineering Taiyuan University of TechnologyTaiyuan 030024People’s Republic of China School of Materials Science and Engineering Tongji UniversityShanghai 201804People’s Republic of China

Rechargeable magnesium batteries(RMBs)have been considered a promising“post lithium-ion battery”system to meet the rapidly increasing demand of the emerging electric vehicle and grid energy storage ***,the sluggish diffusion kinetics of bivalent Mg^(2+)in the host material,related to the strong Coulomb effect between Mg^(2+)and host anion lattices,hinders their further development toward practical *** engineering,regarded as an effective strategy to break through the slow migration puzzle,has been validated in various cathode materials for *** this review,we first thoroughly understand the intrinsic mechanism of Mg^(2+)diffusion in cathode materials,from which the key factors affecting ion diffusion are further ***,the positive effects of purposely introduced defects,including vacancy and doping,and the corresponding strategies for introducing various defects are *** applications of defect engineering in cathode materials for RMBs with advanced electrochemical properties are also ***,the existing challenges and future perspectives of defect engineering in cathode materials for the overall high-performance RMBs are described.

关键词： Rechargeable magnesium battery Sluggish diffusion kinetic Defect engineering Cathode materials Ion migration

Research on Effect of SMA Damper in Passive Control

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Journal of China University of Geosciences 2003年第2期14卷 169-174页

作者： Peng Gang fan Jian li li Tan Jiaxiang College of Civil Engineering & Mechanics, Huazhong University of Science and Technology, Wuhan 430074 College of Civil Engineering & Mechanics Huazhong University of Science and Technology Wuhan 430074

In this article, mechanics model of SMA center tension from damper is developed. According to the theory of Brinson constitutive model and thermodynamics first law, damper thermodynamics non linear equation has been developed. Dynamics non linear equation of frame structure under operation of SMA damper and its solution have been worked out; the software of seismic response analysis for frame structure and of damper characteristic analysis have been compiled with MATLAB software, and the examples have been computed with it. The result indicates that SMA damper has obvious damp characteristics and it can provide with obvious restraint effect for seismic response of frame structure. Decreasing rate of displacement and velocity on top of frame structure reaches 50 %-60 %. The result is in accordance with other pundits experimentation results, which indicates that the above methods are correct and useful.

关键词： shape memory alloy (SMA) transformation pseudo elasticity damper seismic response passive control.

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安全壳冷却系统蒸汽冷凝传热研究综述

原子能科学技术 2016年第11期50卷 1956-1966页

作者：宿吉强范黎高力中国核电工程有限公司北京100840

为保证事故条件下核电厂安全壳的完整性,新一代核电厂广泛采用安全壳冷却系统对事故中释放的蒸汽进行冷却,达到持续稳定导出堆芯蓄热与衰变余热的目的。含不凝性气体(空气、氢气等)的蒸汽在安全壳换热壁面上的冷凝传热成为疏导安全壳内... 详细信息

为保证事故条件下核电厂安全壳的完整性,新一代核电厂广泛采用安全壳冷却系统对事故中释放的蒸汽进行冷却,达到持续稳定导出堆芯蓄热与衰变余热的目的。含不凝性气体(空气、氢气等)的蒸汽在安全壳换热壁面上的冷凝传热成为疏导安全壳内部热量的重要手段。本工作对核电厂事故条件下含不凝性气体蒸汽的冷凝传热进行综述研究,深入全面分析传热过程,提出针对性意见,为核电厂安全壳冷却系统的热工水力研究奠定了基础。

关键词：不凝性气体蒸汽冷凝传热综述

Long-read sequencing reveals novel genetic polymorphisms in the major histocompatibility complex region and their impacts on the Han Chinese population

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Science China life Sciences 2025年

作者： Cong Zhou Tingting Gong Shuhang li li Jin Shaohua fan State Key Laboratory of Genetic Engineering Lab for Evolutionary Synthesis School of Life Sciences Human Phenome Institute Fudan University Research Unit of Dissecting the Population Genetics and Developing New Technologies for Treatment and Prevention of Skin Phenotypes and Dermatological Diseases (2019RU058) Chinese Academy of Medical Sciences

Human leukocyte antigen(HLA) genes in the major histocompatibility complex(MHC) region are crucial for immunity and are associated with numerous diseases and phenotypes. The MHC region's complexity and high genetic diversity make it challenging to analyze using short-read sequencing(SRS) technology. We sequence the MHC region of 100 Han Chinese individuals using both long-read sequencing(LRS) and SRS platforms at approximately 30X coverage to study genetic alterations and their potential functional impacts. LRS provides significantly greater coverage of the MHC region and eight classical HLA genes, particularly at the HLA-DRB1 locus, compared with SRS. We detect 78,249 single nucleotide polymorphisms(SNPs) using LRS, with 26.0% undetectable by SRS. Based on SNP and inferred HLA allele types, we construct an LRS-based MHC reference panel for the Han Chinese, containing approximately 2.6 times more genetic variants than the SRS-based Han-MHC reference panel. A phenome-wide association study assessing 26,024 phenotypes across 15 categories identifies significant associations for 7,879 independent variants(including 809 LRS-specific SNPs) with 409 phenotypes in nine categories. This analysis reveals 24 unreported HLA allele associations in the bioelectric and cellular categories. The conditional analysis identifies 530independent signals across the 409 phenotypes, including 28 previously unreported signals of eight classical HLA genes associated with 33phenotypes. Of the top-associated SNPs, 191 are detected by LRS only. Fine-mapping identifies 126 independent candidate causal SNPs for three immune-related cellular phenotypes, with 17 detected exclusively by LRS. Our study reveals previously unreported variants and their functional impacts in the MHC region, enhancing our understanding of genetic diversity and its potential biological implications in the Han Chinese population.

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我国信息资源产业发展制度环境的构建与完善

情报科学 2008年第8期26卷 1155-1160,1178页

作者：范丽莉长安大学人文学院陕西西安710064

信息社会,发展信息资源产业已经成为加强信息资源开发利用的必然选择。鉴于制度环境对信息资源产业的重要性,本文从市场准入、产权安排、公平竞争、激励机制、市场监管、投融资体系等方面探讨了如何构建和完善我国信息资源产业发展的制... 详细信息

信息社会,发展信息资源产业已经成为加强信息资源开发利用的必然选择。鉴于制度环境对信息资源产业的重要性,本文从市场准入、产权安排、公平竞争、激励机制、市场监管、投融资体系等方面探讨了如何构建和完善我国信息资源产业发展的制度环境。

关键词：信息资源产业制度安排

羟苯氨酮对离体鼠心停灌-复灌损伤的保护作用

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药学学报 2005年第8期40卷 705-710页

作者：范礼理李华范明杰张润东中国医学科学院中国协和医科大学药物研究所北京100050

目的研究羟苯氨酮对全心停灌复灌损伤的影响。方法采用离体大鼠心脏停灌40min复灌30min模型,从心脏功能、心肌能量代谢、抗氧化、线粒体钙超载及超微结构等方面观察药物作用。结果停灌前和复灌时给予羟苯氨酮(1～10μmol·L-1)明显增加... 详细信息

目的研究羟苯氨酮对全心停灌复灌损伤的影响。方法采用离体大鼠心脏停灌40min复灌30min模型,从心脏功能、心肌能量代谢、抗氧化、线粒体钙超载及超微结构等方面观察药物作用。结果停灌前和复灌时给予羟苯氨酮(1～10μmol·L-1)明显增加复灌时心肌收缩力与冠脉流量,降低冠脉流出液的肌酸磷酸激酶(CPK)活性,对抗损伤所致的心肌三磷酸腺苷(ATP)与磷酸肌酸(PCr)含量降低,增强心肌抗氧化能力,对抗线粒体钙超载,使线粒体超微结构保持得比较完整。结论羟苯氨酮明显对抗停灌复灌致心肌损伤,为该药保护再灌注损伤提出有力依据。

关键词：羟苯氨酮心脏停灌-复灌线粒体心肌能量代谢抗氧化钙超载