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Epidemiological Characteristics of Leprosy in China,2.18

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international Journal of Dermatology and Venereology 2020年第1期3卷 27-30页

作者： wang Le Sun Pei-Wen Yu Mei-Wen Gu Heng wang Hong-Sheng Chen Xiang-Sheng National center for Leprosy Control Chinese Centers for Disease Control and PreventionHospital for Skin Diseases(Institute of Dermatology)Chinese Academy of Medical Sciences and Peking Union Medical CollegeNanjingJiangsu 210042China

Objective::To describe the epidemiological characteristics of leprosy in China in 2.18 and provide the essential evidences for leprosy ***::We collected data of leprosy cases nationwide from Leprosy Management Information System in China(LEPMIS)except Hong Kong,Macao,and *** then we performed a descriptive and comparative ***::A total of 52. new leprosy cases were detected nationwide in 2.18,with a case detection rate of 0.03./100,*** proportion of children under 15 years of age,multi-bacillary(MB)cases,and cases with WHO grade 2.disability(G2.)were 1.3.,89.4.,and 19.0%,*** were 2.4.9 registered cases of leprosy in China by the end of 2.18,accounting for a prevalence rate of 0.178/100,000,with 4.3}replase *** China separately accounted for 3.2.52.(59.9%)newly detected cases and 1,180/2.4.9(4..6%)registered cases of leprosy in ***::China is a low endemic country for leprosy and the detection rate was much lower than the global *** China is still the {14.y regions for leprosy control,including Yunnan,Guizhou,and *** addition,leprosy in low endemic provinces also needs to be focused.

关键词： leprosy epidemiology China endemic

The Relationship between Total Ozone and Local Climate at Kunming Using Dobson and TOMS Data

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Atmospheric and Oceanic Science Letters 2010年第4期3卷 207-212页

作者： wang Jun wang Hui-Jun nansen-zhu {2. {3. Centre Institute of Atmospheric Physics Chinese Academy of Sciences Beijing 100029 China Climate Change research center Institute of Atmospheric Physics Chinese Academy of Sciences Beijing 100029 China Graduate University of chinese academy of sciences Beijing 100049 China

This paper uses Dobson spectrometer total ozone data,Total Ozone Mapping Spectrometer(TOMS) data and radiosonde reports from Kunming,which is located in southwest China,from 1980 to 2.08 to analyze the total ozone-climate *** total ozone decadal long-term trend and abrupt change were studied using enhanced Dobson data whose missing data were amended by the TOMS *** linear regression was used for the selection of the key factors that influence total ozone,including temperatures,geopotential heights,depressions of the dew point,wind velocities,and total solar *** relationship between the selected factors and total ozone was analyzed using the methods of stepwise regression and partial least squares regression(PLSR).Results showed that although the PLSR method was slightly better and more reasonable to study the relationship than stepwise regression,while the two regression results were only slightly *** was also suggested that local climate,especially local circulation and temperature,were important for the variations in total ozone,and the local climate could almost linearly explain 80% of the variance of total *** relationship also indicated that the abrupt change of total ozone in the year 1994.may be related to abrupt local climate change.

关键词： Dobson TOMS Total ozone partial least squares regression

Efficacy and safety of LY01005 versus goserelin implant in chinese patients with prostate cancer: A multicenter, randomized, open-label, phase III, non-inferiority trial

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chinese Medical Journal 2023年第10期136卷 1207-1215页

作者： Chengyuan Gu Zengjun wang Tianxin Lin Zhiyu Liu Weiqing Han Xuhui Zhang Chao Liang Hao Liu Yang Yu Zhenzhou Xu Shuang Liu Jingen wang Linghua Jia Xin Yao Wenfeng Liao Cheng Fu Zhaohui Tan Guohua He Guoxi {2. Rui {3. Wenzeng Yang Xin Chen Zhizhong Liu Liqiang Zhong Benkang Shi Degang Ding Shubo Chen Junli Wei Xudong Yao Ming Chen Zhanpeng Lu Qun Xie Zhiquan Hu Yinhuai wang Hongqian Guo Tiwu {3. Zhaozhao Liang Peng Chen Wei wang Tao Xu Chunsheng Li Jinchun Xing Hong Liao Dalin He Zhibin Wu Jiandi Yu Zhongwen Feng Mengxiang Yang Qifeng Dou Quan Zeng Yuanwei Li Xin Gou Guangchen Zhou Xiaofeng wang Rujian {2. Zhonghua Zhang Bo Zhang Wanlong Tan Xueling Qu Hongliang Sun Tianyi Gan Dingwei Ye Department of Urology Fudan University Shanghai Cancer CenterShanghai 200032China Department of Oncology Shanghai Medical CollegeFudan UniversityShanghai 200032China Department of Urology The First Affiliated Hospital of Nanjing Medical UniversityNanjingJiangsu 210029China Department of Urology Sun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhouGuangdong 510120China Department of Urology The Second Affiliated Hospital of Dalian Medical UniversityDalianLiaoning 116023China Department of Urology The Affiliated Cancer Hospital of Xiangya School of MedicineCentral South UniversityHunan Cancer CenterChangshaHunan 410013China Department of Urology First Hospital of Shanxi Medical UniversityTaiyuanShanxi 030000China Department of Urology Jiangxi Provincial People’s HospitalSchool of MedicineNanchang UniversityNanchangJiangxi 330006China Department of Urology Tianjin Medical University Cancer Institute and HospitalTianjin 300060China Department of Urology Cancer Hospital of China Medical UniversityLiaoning Cancer Hospital and InstituteShenyangLiaoning 110043China Department of Urology Inner Mongolia People’s HospitalHohhotInner Mongolia 010010China Department of Urinary Surgery Taizhou Hospital of Traditional Chinese MedicineTaizhouJiangsu 225300China Department of Urology Linfen People’s HospitalLinfenShanxi 041000China Department of Urology Zhengzhou Central Hospital Affiliated to Zhengzhou UniversityZhengzhouHenan 450006China Department of Urology The Affiliated Hospital of Hebei UniversityBaodingHebei 071000China Department of Urology Chifeng Municipal HospitalChifeng Clinical Medical College of Inner Mongolia Medical UniversityChifengInner Mongolia 024000China Department of Urology Baogang HospitalBaotouInner Mongolia 014010China Department of Oncology The Second People’s Hospital of YibinYibinSichuan 644000China Department of Urology Qilu Hospital of Shandong UniversityJinanShandong 250014China Department of Urology Henan Provincial People’s Hos

Background:LY01005(Goserelin acetate sustained-release microsphere injection)is a modified gonadotropin-releasing hormone(GnRH)agonist injected *** phase III trial study aimed to evaluated the efficacy and safety of LY01005 in chinese patients with prostate ***:We conducted a randomized controlled,open-label,non-inferiority trial across 4. sites in *** study included 2.0 patients with prostate cancer who received either LY01005 or goserelin implants every 2. days for three *** primary efficacy endpoints were the percentage of patients with testosterone suppression≤50 ng/dL at day 2. and the cumulative probability of testosterone≤50 ng/dL from day 2. to ***-inferiority was prespecified at a margin of-10%.Secondary endpoints included significant castration(≤2. ng/dL),testosterone surge within 72.h following repeated dosing,and changes in luteinizing hormone,follicle-stimulating hormone,and prostate specific antigen ***:On day 2.,in the LY01005 and goserelin implant groups,testosterone concentrations fell below medical-castration levels in 99.3.(14.9}4.8}and 100%(14./14.)of patients,respectively,with a difference of-0.7%(95%confidence interval[CI],-3.9%to 2.0%)between the two *** cumulative probabilities of maintaining castration from days 2. to 85 were 99.3.and 97.8%,respectively,with a between-group difference of 1.5%(95%CI,-1.3.to 4.4.).Both results met the criterion for *** endpoints were similar between *** treatments were ***01005 was associated with fewer injection-site reactions than the goserelin implant(0%vs.1.4.[2.14.]).Conclusion:LY01005 is as effective as goserelin implants in reducing testosterone to castration levels,with a similar safety *** registration:***,NCT04.63.3..

关键词： Prostatic neoplasms LY01005 Gonadotropin-releasing hormone agonist Efficacy Safety

Smart control system for the precision cultivation of black fungus

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international Journal of Agricultural and Biological Engineering 2023年第1期16卷 193-202页

作者： Yongcheng Jiang Jianjun Li Yang Li Shide Li Xin Song Haiyun Wu Shiwei zhu College of Engineering and Technology Tianjin Agricultural UniversityTianjin 300392China College of Mechanical Engineering Jiamusi UniversityJiamusi 154007HeilongjiangChina School of Innovation and Entrepreneurship/School of E-Business Yangzhou Polytechnic InstituteYangzhou 225000JiangsuChina College of Basic Science Tianjin Agricultural UniversityTianjin 300392China

Black fungus,with high nutritional and medicinal value,has been cultivated in China for a long time,and Heilongjiang alone accounts for about 4.%of the global *** present,the cultivation of black fungus derives mainly from the inheritance of relatively primitive practices and experience of farmers,resulting in inconsistent quality of *** this study,a smart control system for the precision cultivation of black fungus was designed by using intelligent detection and control *** system includes a precision culture test environment and remote control *** precision cultivation environment contains four sub-independent *** key parameters such as temperature,humidity,and light behavior were collected and can be adjusted individually,according to the precision cultivation *** intelligent remote control system included a controller cabinet,sensors unit,temperature control unit,humidity control unit,light control unit,and information transmitting *** controller cabinet includes a key controller which can auto-control the temperature,humidity,and lightly adjust components according to the precision cultivation conditions and *** temperature sensors were installed in a 3. array close to the fungus bags about 5 cm in *** light tape was installed on the six walls and also had three colors(Red,Blue,and Green)which could be controlled independently in each *** control strategy through the analysis of the data collected by all sensors,the current cultivate situation of the cultivation environment was obtained,and the heater,{2.,light,and nozzle were regulated according to the strategy to maintain a suitable precision cultivation environment for *** verify the feasibility of the precision cultivation processing and control system,the test result shows that the error of temperature control was about 0℃-1℃,the error of humidity control was about 1%-4.,and the error of illuminance control was about 0-50 lx

关键词： black fungus precision cultivation smart control system growth environment remote control system sensor

维普期刊数据库评论

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X线骨龄评估方法研究进展与展望

法医学杂志 2007年第5期23卷 365-369页

作者：王亚辉朱广友乔可卞士中范利华程亦斌应充亮沈彦苏州大学医学院基础医学系江苏苏州215123 司法部司法鉴定科学技术研究所上海200063 西安交通大学医学院第二附属医院陕西西安710004

骨龄评估的传统方法主要包括计数法、图谱法及计分法等,近年来又有一些学者不断提出其他新的方法。利用骨骼X线片影像学特征推断骨龄是当前法医学工作者进行骨龄评估的主要手段。但是,将此骨龄推断结论作为"证据"直接提供给司法审判机关... 详细信息

骨龄评估的传统方法主要包括计数法、图谱法及计分法等,近年来又有一些学者不断提出其他新的方法。利用骨骼X线片影像学特征推断骨龄是当前法医学工作者进行骨龄评估的主要手段。但是,将此骨龄推断结论作为"证据"直接提供给司法审判机关,因其存在着一定的误差尚值得商榷。因此,为了提高骨龄鉴定结论的精确度,还需进行更多方法学的研究。经参阅国内、外大量相关文献,现就X线片骨龄评估方法的研究与进展进行综述。

关键词： X线片骨龄评估方法计分法法医学骨龄鉴定

我国白酒蒸馏过程及原酒、成品酒中乙醛的研究

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食品与发酵工业 2016年第4期42卷 6-11页

作者：朱梦旭范文来徐岩教育部工业生物技术重点实验室江南大学生物工程学院酿造微生物与应用酶学研究室江苏无锡214122

乙醛广泛存在于酒精饮料中,被国际癌症研究机构（IARC）确认为Ⅰ类致癌物（对人类致癌证据充分）。利用气相色谱-氢火焰离子化检测（GC-FID）技术检测我国馏分酒、原酒和成品白酒中乙醛,发现白酒固态蒸馏和液态二次蒸馏过程中乙醛和乙... 详细信息

乙醛广泛存在于酒精饮料中,被国际癌症研究机构（IARC）确认为Ⅰ类致癌物（对人类致癌证据充分）。利用气相色谱-氢火焰离子化检测（GC-FID）技术检测我国馏分酒、原酒和成品白酒中乙醛,发现白酒固态蒸馏和液态二次蒸馏过程中乙醛和乙缩醛很快被馏出,含量较集中于前几个馏分,随着蒸馏进行,含量逐渐减少。原酒中乙醛质量浓度在4..10-763.93.mg/L,乙缩醛的质量浓度在61.50-2.871.52.mg/L,乙缩醛和乙醛的比例在2.2.∶1-2.87∶1。成品白酒中乙醛质量浓度4.7}6-4.1.70 mg/L,乙缩醛的质量浓度在68.54.811.3.0}mg/L,乙缩醛和乙醛的比例在1.2.∶1-1.96∶1,且成品白酒乙醛的平均质量浓度（173.2. mg/L）高于其他国家蒸馏酒中乙醛的质量浓度（≤86 mg/L）。我国成品白酒中乙醛的暴露边界（margin of exposure,MOE）值为62.,因此白酒中乙醛对人类健康的潜在危害应给予较高关注。

关键词：乙醛乙缩醛蒸馏原酒成品酒暴露边界

我国白酒蒸馏过程以及不同年份产原酒和成品酒中甲醛的研究

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食品与发酵工业 2015年第9期41卷 153-158页

作者：朱梦旭范文来徐岩教育部工业生物技术重点实验室江南大学生物工程学院酿造微生物与应用酶学研究室江苏无锡214122

甲醛广泛存在于酒精饮料中,被国际癌症研究机构(IARC)确认为Ⅰ类致癌物(对人类致癌证据充分)。利用o-(2.3,4.5,6-五氟苄基)羟胺(PFBHA)衍生与顶空固相微萃取-气相色谱-质谱(HS-SPME-GC-MS)联用技术检测我国馏分酒、不同年份产原酒和成... 详细信息

甲醛广泛存在于酒精饮料中,被国际癌症研究机构(IARC)确认为Ⅰ类致癌物(对人类致癌证据充分)。利用o-(2.3,4.5,6-五氟苄基)羟胺(PFBHA)衍生与顶空固相微萃取-气相色谱-质谱(HS-SPME-GC-MS)联用技术检测我国馏分酒、不同年份产原酒和成品白酒中甲醛,发现白酒固态蒸馏过程中甲醛呈现先下降后上升再下降的趋势,白酒二次蒸馏过程中甲醛的变化与固态蒸馏类似。原酒中有15个酒样(占样品总量的16%)的甲醛浓度高于国际化学品安全规划(IPCS)建议的产品中甲醛的允许浓度(2.6 mg/L)。总体上讲,生产年份越早,原酒中甲醛浓度越高。成品酒中仅有3.酒样(0.09%)高于2.6 mg/L,但我国成品白酒甲醛平均浓度(0.89 mg/L)普遍高于其他国家蒸馏酒中甲醛的浓度(≤0.7 mg/L).

关键词：甲醛衍生化蒸馏原酒成品酒

国际旅游研究趋势特点与规律:基于1985—2.15年Web of Science收录文献的分析

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旅游学刊 2019年第3期34卷 125-133页

作者：刘俊任泽伟王胜宏李云云朱江欢陈帆王灵恩四川大学旅游学院四川成都610065 中国科学院地理科学与资源研究所北京100101 中国科学院大学北京100049

基于综合数据库对旅游研究进展进行文献梳理能够避免单类期刊主题的局限,更加客观全面地反映旅游学科的多学科交叉特征和实际。文章通过主题词筛选,对1985—2.15年Web of Science数据库收录的2. 591篇旅游研究文献进行了系统的文献计量... 详细信息

基于综合数据库对旅游研究进展进行文献梳理能够避免单类期刊主题的局限,更加客观全面地反映旅游学科的多学科交叉特征和实际。文章通过主题词筛选,对1985—2.15年Web of Science数据库收录的2. 591篇旅游研究文献进行了系统的文献计量分析。分析发现:(1)通过多年的发展,旅游已成为国际科学研究的重要领域,一些旅游研究领域的国际学术期刊成为旅游学科知识创新和传播的稳定载体;(2.旅游研究展现了鲜明的多学科交叉特征,研究领域与方法涉及社会科学和自然科学的各个范畴;(3.国际旅游研究呈现出以Wall G、Bec{3.n S、Nunkoo R、Rogerson C M和Saarinen J等为中心的作者合作群,以及以香港理工大学、澳大利亚格里菲斯大学、加拿大滑铁卢大学和英国萨里大学为中心的基本格局;(4.可持续旅游、乡村旅游等是过去3.年旅游研究的热点主题,气候变化等国际科学热点在旅游研究领域体现充分,中国逐步成为旅游研究的热点区域。

关键词：旅游发展文献计量网络分析国际

Twentieth-century Pacific Decadal Oscillation simulated by CMIP5 coupled models

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Atmospheric and Oceanic Science Letters 2018年第1期11卷 94-101页

作者： wang Tao MIAO Jia-Peng anansen-zhu {2. {3.{4. Institute of Atmospheric Physics Chinese Academy of Sciences Beijing China Collaborative Innovation center on Forecast and Evaluation of Meteorological Disasters Nanjing University of Information Science and Technology Nanjing China College of Earth sciences University of Chinese Academy of Sciences Beijing China

The authors examine the spatial and temporal characteristics of the simulated Pacific Decadal Oscillation （PDO） in 109 historical （i.e. all forcings） simulations derived from 2. coupled models within CMIPS. Compared with observations, most simulations successfully simulate the observed PDO pattern and its teleconnections to the SSTs in the tropical and southern Pacific. BNU-ESM, CanESM2. CCSM4. CESM 1 -FASTCHEM, FGOALS-g2. GFDL CM3. MIROCS, and NorESM 1 -M show better performance. Compared with the temporal phases of the observed PDO in the twentieth century, only five simulations -- from CNRM^CMS, CSIRO Mk3.6.0, HadCM3. and IPSL-CMSA-LR -- simulate an evolution of the PDO similar to that derived from observation, which suggests that current coupled models can barely reproduce the observed phase shifting of the PDO. To capture characteristics of the observed PDO in the twentieth century, a requirement is that all the relevant external forcings are included in the models. How to add realistic oceanic initial states into the model may be another {3.y point.

关键词： Pacific Decadal Oscillation CMIPS twentieth century coupled model