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辛伐他汀对脑动脉粥样硬化患者炎性因子和血脂的影响

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临床医学研究与实践 2018年第13期3卷 26-27页

作者：李立娟樊强合阳县中医院陕西渭南715300 陕西省宝鸡市陈仓区陈仓医院陕西宝鸡721300

目的研究辛伐他汀对脑动脉粥样硬化患者炎性因子和血脂的影响。方法将我院收治的2.0例脑动脉粥样硬化患者根据治疗方法分为A组和B组,各100例。A组行常规治疗,B组在A组基础上运用辛伐他汀。比较两组的治疗效果。结果治疗后,两组患者的CRP... 详细信息

目的研究辛伐他汀对脑动脉粥样硬化患者炎性因子和血脂的影响。方法将我院收治的2.0例脑动脉粥样硬化患者根据治疗方法分为A组和B组,各100例。A组行常规治疗,B组在A组基础上运用辛伐他汀。比较两组的治疗效果。结果治疗后,两组患者的CRP、IL-6、IL-18、HDL-C、TC、LDL-C及TG水平明显优于治疗前,且B组明显优于A组(P<0.05)。结论对脑动脉粥样硬化患者采取辛伐他汀进行治疗,不仅可以降低炎性因子水平,还能改善患者的血脂水平,有利于进一步提高治疗效果。

关键词：脑动脉粥样硬化辛伐他汀炎性因子血脂

Complete Universal Scaling in First-Order Phase Transitions

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Chinese Physics Letters 2024年第10期41卷 8-13页

作者： fan Zhong School of Physics and State Key Laboratory of Optoelectronic Materials and Technologies Sun Yat-sen UniversityGuangzhou 510275China

Phase transitions and critical phenomena are among the most intriguing phenomena in nature and *** are classified into first-order phase transitions(FOPTs)and continuous *** the latter shows marvelous phenomena of scaling and universality,whether the former behaves similarly is a long-standing controversial *** we definitely demonstrate complete universal scaling in field driven FOPTs for Langevin equations in both zero and two spatial dimensions by rescaling all parameters and subtracting nonuniversal contributions with singular dimensions from an effective temperature and a special field according to an effective *** offers a perspective different from the usual nucleation and growth but conforming to continuous phase transitions to study FOPTs.

关键词： theory. transitions scaling

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国内外药物临床试验GCP检查概述与启示

中国药事 2018年第4期32卷 423-431页

作者：万征范玉明国家食品药品监督管理总局高级研修学院北京100073 中国食品药品检定研究院北京100050

本文概述了美国、欧盟、日本和中国的GCP检查要求,对GCP检查中涉及的组织机构、检查员数量及能力、检查与稽查类型、检查对象、检查过程、检查评价、处罚措施等方面进行分析和比较,为我国GCP检查制度的改革提供参考。

关键词：药物临床试验质量管理规范 GCP检查有因检查常规性检查集中检查计划当地检查计划 GCP现场检查药物评价和研究中心试验和研究办公室管理事物办公室

14个类型流苏树叶片和叶柄解剖学特征的比较研究

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中国农业大学学报 2018年第5期23卷 38-51页

作者：陈弯樊莉丽许笑蒙邢国珍郑文明樊巍李春奇河南农业大学生命科学学院郑州450002 河南省林业科学研究院生态林业工程技术研究中心郑州450002

为系统地研究流苏树的分类、形态特征和解剖特征,对华北地区14个主要类型的流苏树的形态特征和叶片及叶柄的解剖学特征进行分析。形态比较结果表明:14个不同类型的流苏树在外观形态有显著差异,其树冠、枝姿、树皮性状和叶形等形态特征... 详细信息

为系统地研究流苏树的分类、形态特征和解剖特征,对华北地区14个主要类型的流苏树的形态特征和叶片及叶柄的解剖学特征进行分析。形态比较结果表明:14个不同类型的流苏树在外观形态有显著差异,其树冠、枝姿、树皮性状和叶形等形态特征都有显著不同,反映类型间可能存在遗传分化;解剖结构的观察结果显示:1)14个类型流苏树叶片均为异面叶,表皮细胞和栅栏组织均为1层,排列紧密,叶片和叶柄表面均覆有毛被和角质层;2.叶片和叶柄横切面结构有差异,叶柄中部横切面形状均为近半圆形,但维管束轮廓有近半圆形、半圆形和近圆形3种形状;3)维管束类型均为近周韧,但每个类型的维管束数目和大小都不尽相同。并根据筛选出的19个解剖特征数据对14个类型流苏树的分化关系进行聚类分析。综合比较形态和解剖特征可以发现在各类型之间差异比较明显,可为流苏树的类型鉴定及植株选优提供依据,在株型定向培育和资源鉴定方面具有一定的理论和应用价值。

关键词：流苏树叶片叶柄解剖学分类学

Semi-analytical Solutions for Wellbores with Graded Skin Zones in Poroelastic Media

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Acta Mechanica Solida Sinica 2024年第3期37卷 385-395页

作者： Zhiqiang fan Zhihe Jin School of Mechanics Civil Engineering and ArchitectureNorthwestern Polytechnical UniversityXi’an710072China Department of Mechanical Engineering University of MaineOronoME04469USA

In analyzing the complex interaction between the wellbore and the reservoir formation,the hydromechanical properties of the region proximal to the wellbore,referred to as the“wellbore skin zone”,play a pivotal role in determining flow dynamics and the resulting formation *** models of the wellbore skin zone generally assume a constant permeability throughout,resulting in a sharp permeability discontinuity at the skin-reservoir *** paper introduces a model for a wellbore with a continuously graded skin zone of finite thickness within a poroelastic *** solutions are derived using the Laplace transform method,addressing both positive and negative skin *** results are presented to illustrate the effects of graded permeability/skin zone thickness on pore pressures and stresses around a *** results highlight a distinct divergence in stress and pore pressure fields when comparing wellbores with negative skin zones to those with positive skin zones or no skin at all.

关键词： Poroelastic Graded permeability Analytical solution Wellbore Skin zone

A progressive framework for rotary motion deblurring

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Defence Technology（防务技术） 2024年第2期32卷 159-172页

作者： Jinhui Qin Yong Ma Jun Huang fan fan You Du School of Electronic Information Wuhan UniversityWuhan430072China

The rotary motion deblurring is an inevitable procedure when the imaging seeker is mounted in the rotating *** rotary motion deblurring methods suffer from ringing artifacts and noise,especially for large blur *** solve the above problems,we propose a progressive rotary motion deblurring framework consisting of a coarse deblurring stage and a refinement *** the first stage,we design an adaptive blur extents factor(BE factor)to balance noise suppression and details *** a novel deconvolution model is proposed based on BE *** the second stage,a triplescale deformable module CNN(TDM-CNN)is designed to reduce the ringing artifacts,which can exploit the 2. information of an image and adaptively adjust spatial sampling *** establish a standard evaluation benchmark,a real-world rotary motion blur dataset is proposed and released,which includes rotary blurred images and corresponding ground truth images with different blur *** results demonstrate that the proposed method outperforms the state-of-the-art models on synthetic and real-world rotary motion blur *** code and dataset are available at https://***/JinhuiQin/RotaryDeblurring.

关键词： Rotary motion deblurring Progressive framework Blur extents factor TDM-CNN

Seismic response of pile-supported structures considering the coupling of inertial and kinematic interactions in different soil sites

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Frontiers of Structural and Civil Engineering 2024年第9期18卷 1350-1361页

作者： Huiling ZHAO fan ZHANG Department of Civil Engineering Shanghai UniversityShanghai 200444China

Dynamic soil−pile−superstructure interaction is crucial for understanding pile behavior in earthquake-prone *** the safety of piles requires determining the seismic bending moment caused by combined inertial and kinematic interactions,which is *** paper addresses this problem through numerical simulations of piles in different soil sites,considering soil *** reveal that the period of the soil site significantly affects the interaction among soil,piles,and *** moments in soft and hard soil sites exceed those in medium soil sites by more than *** modes of piles exhibit distinct characteristics between hard and soft soil *** soil sites exhibit a singular inflection point,while hard soil sites show two inflection *** soft soil sites,pile-soil kinematic interaction gradually increases bending moment from tip to head,with minor influence from superstructure’s inertial *** hard soil sites,significant inertial effects from soil,even surpassing pile-soil kinematic effects near the tip,lead to reversed superposition bending ***’s inertial interaction notably impacts pile head in hard soil sites.A simplified coupling method is proposed using correlation coefficient to represent inertial and kinematic *** findings provide insights into complex seismic interactions among soil,piles,and structures.

关键词： pile seismic response soft soil inertial interaction kinematic interaction

Impact of non-ideal UE hardware on cell-free massive MIMO network with centralized operation

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Science China(Information Sciences) 2024年第4期67卷 255-271页

作者： Ning LI Pingzhi fan Institute of Mobile Communications Southwest Jiaotong University

This paper investigates the impact of non-ideal user equipment(UE) hardware on a cell-free(CF) massive MIMO(mMIMO) network with centralized operation under spatially correlated channels. The minimum mean-squared error(MMSE) estimator can be derived with the help of the generic non-ideal UE hardware model. It is demonstrated that even if the effective signal-to-noise ratio approaches infinity, pilot contamination and imperfect hardware can cause a non-zero estimation error floor. After that, a lower bound is determined for the ergodic uplink capacity of the centralized CF mMIMO network under non-ideal UE hardware. Moreover, the optimal receive combining vector is obtained to maximize the uplink spectral efficiency(SE). The maximum ratio(MR) and regularized zero-forcing(RZF) combining schemes are offered as alternatives in light of the computational complexity of the MMSE receiver. Comparing the RZF to the MMSE scheme under different levels of hardware impairments, our findings indicate that the RZF receiver suffers a negligible loss in total SE. For MR combining, a novel closed-form uplink achievable SE expression is obtained based on the MMSE estimator and the use-and-then-forget bounding technique. This expression gives vital insights into the achievable uplink performance with UE hardware impairments. Besides, for various hardware impairment factors, the impact of pilot sequence length on average sum SE is disclosed for different receive combining schemes. To increase the overall SE of the max-min fairness scheme, a heuristic fractional power control scheme with UE hardware impairments is developed, which can essentially avoid sacrificing the SE of other UEs while maximizing the SE of the unluckiest UE in the whole network. Finally,our theoretical performance analysis and power control algorithm are validated by simulation results, and fundamental design guidelines are provided for selecting hardware satisfying the practical UE requirements.

关键词： cell-free massive MIMO centralized operation spatially correlated channels hardware impairments channel estimation uplink spectral efficiency optimal receive combining pilot length design fractional power control

Bi_(2.WO_(6)/AgInS_(2.S-scheme heterojunction:Efficient photodegradation of organic pollutant and toxicity evaluation

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Journal of Materials Science & Technology 2024年第3期170卷 200-211页

作者： Yanyan Zhao Xu fan Hongxing Zheng Enzhou Liu Jun fan Xuejun Wang College of Biology Pharmacy and Food Engineering Shangluo UniversityShangluo 726000China QinLing-Bashan Mountains Bioresources Comprehensive Development C.I.C. Shaanxi University of TechnologyHanzhong 723001China School of Chemical Engineering Northwest UniversityXi’an 710069China

Constructing of heterojunction was identified as a feasible way to improve photocatalytic activity of *** this work,a n-p type Bi_(2.WO_(6)/AgInS_(2.S-scheme heterojunction was successfully prepared for organic pollutants *** Bi_(2.WO_(6)/AgInS_(2.S-scheme heterojunction exhibited much higher pho-tocatalytic activity towards Rhodamine B(92.2.%,expose to visible light for 60 min),norfloxacin(81.73%,expose to visible light for 90 min)and levofloxacin(87.46%,expose to visible light for 90 min)than pure Bi_(2.WO_(6)and pure AgInS_(2..Toxicity analysis indicated the low environmental toxicity of Rhodamine B degradation intermediates for Rye seeds and Sudangrass seeds germination and *** study displayed that AgInS_(2.and Bi_(2.WO_(6)work as the primary photocatalyst to form·O_(2.−and ·OH,*** improved photocatalytic activity of the Bi_(2.WO_(6)/AgInS_(2.S-scheme heterojunction was due to the im-proved light response range and intensified carrier separation ***,a S-scheme charge transfer mechanism including multiple charge transfer channels was *** work could provide an effective strategy for organic pollutants degradation in wastewater.

关键词： Photocatalysis S-scheme heterojunction AgInS_(2. Bi_(2.WO_(6) Toxicity experiments