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Chinese Physics Letters 2005年第1期22卷 69-71页

作者： f.N.Khattak E.u.khan TabassumNasir J.J.Baluch f.u.khan u.W.C. GomalUniversityDeraIsmailKhanPakistan RadiationPhysicsDivision PINSTECHNiloreIslamabadPakistan DepartmentofPhysics GomalUniversityDeraIsmailKhanPakistan

Two detector materials mica and cellulose-nitrate(CN)-85 have been used to study (14.0MeV/u) Pb + Pb reaction. Events of different multiplicities were registered in mica and CN-85 detectors using the 2π-geometry technique of solid state nuclear track detection. After removing the target material from the detectors the damaged trails in the detectors were revealed as tracks by proper chemical etching. The irradiated area of each sample was scanned and events of different multiplicities were traced. The binary events were bifurcated into elastic and inelastic events. The elastic binary events and three prong events, observed in the reaction, have been used to search out coefficients Cμν in the presence of both the detectors, for the reaction under study. using these coefficients 3- and 4-prong events have been analysed. from the detailed analysis of the results of (14.0MeV/u) Pb+Pb reaction, obtained from mica and CN-85 track detectors we observed a great resemblance of results obtained from the two detectors. Combining the results of both the detectors, we report some important outcomes.

关键词： CN-85轨迹探测器高能物理学铅原子碰撞反应固态

Magnesium (II) Adsorption from Aqueous Solutions on China Clay and the Stability Constants for Complex formation

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Pedosphere 1998年第2期8卷 169-174页

作者： S．BEGuM f.u.khan PakistanCouncilofScientificandIndustrialResearchLabs Peshawer（Pakistan） PakistanCouncilofScientifican

China clay was employed as an adsorbent for the removal of Mg 2+ from water at pH 7.0 within the temperature range of 303～328 K. The linearity of the plots indicated Langmuir type isotherms. The reaction was exothermic. A maximum removal of 35% was obtained at 0.50 mmol L -1 metal concentration and a pH of 7.0 at 303 K. The H + rel /Mg 2+ ads ratio changed from a fractional value to 2.5. Strong chemical bondings took place between oxygen atom of the surface and Mg 2+ , resulting in a surface complex species. Temperature had a significant effect on H + rel , and the stability constants also increased with increasing temperature.

关键词： H + releasing Mg 2+ adsorption stability constants temperature

Trace-Rare-Gas Optical Emission Spectroscopy of Nitrogen Plasma Generated at a frequency of 13.56 MHz

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Plasma Science and Technology 2011年第2期13卷 208-212页

作者： N.u.REHMAN f.u.khan S.NASEER G.MuRTAZA S.S.HuSSAIN I.AHMAD M.ZAKAuLLAH Department of Physics COMSATS Institute of Information Technology Department of Physics Gomal University Department of Physics Peshawar University Department of Physics Quaid-i-Azam University

Optical emission spectroscopic measurement of trace rare gas is carried out to determine the density of nitrogen （N） atom, in a nitrogen plasma, as a function of filling pressure and Rf power applied. 2% of argon, used as an actinometer, is mixed with nitrogen. In order to normalize the changes in the excitation cross section and electron energy distribution function at different operational conditions, the Ar-I emission line at 419.83 nm is used, which is of nearly the same excitation efficiency coefficient as that of the nitrogen emission line at 493.51 nm. It is observed that the emission intensity of the selected argon and atomic nitrogen lines increases with both pressure and Rf power, as does the nitrogen atomic density.

关键词： optical actinometry N atomic density EEDf Rf plasma

Hsa-miR-214-3p inhibits breast cancer cell growth and improves the tumor immune microenvironment by downregulating B7H3

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Oncology research 2025年第1期33卷 103-121页

作者： Yan Lu Kang Wang Yuanhong Peng Meng Chen Lin Zhong Luji Huang f u Cheng Xindan Sheng Xin Yang Manzhao Ouyang George A Calin Zhiwei He China-America Cancer Research Institute Guangdong Medical University Dongguan 523808 China. GCP Center Shunde Hospital Southern Medical University (The First People's Hospital of Shunde Foshan) Shunde 528300 China. Department of Gastrointestinal Surgery Shunde Hospital Southern Medical University (The First People's Hospital of Shunde Foshan) Shunde 528300 China. The Second School of Clinical Medicine Southern Medical University Guangzhou 510080 China. Department of Translational Molecular Pathology The University of Texas MD Anderson Cancer Center Houston TX 77030 USA. Department of Oncology Shunde Hospital Southern Medical University (The First People's Hospital of Shunde Foshan) Shunde 528300 China.

Background:Immune checkpoint inhibitors play an important role in the treatment of solid tumors, but the currently used immune checkpoint inhibitors targeting programmed cell death-1 (PD-1), programmed cell death ligand-1 (PD-L1), and cytotoxic T-lymphocyte antigen-4 (CTLA-4) show limited clinical efficacy in many breast cancers. B7H3 has been widely reported as an immunosuppressive molecule, but its immunological function in breast cancer patients remains unclear.Methods:We analyzed the expression of B7H3 in breast cancer samples using data from the Cancer Genome Atlas Program (TCGA) and the Gene Expression Omnibus (GEO) databases. MicroRNAs were selected using the TarBase, miRTarBase, and miRBase databases. The regulatory role of the microRNA hsa-miR-214-3p on B7H3 was investigated through dual-luciferase reporter assays, which identified the specific action sites of interaction. The expression levels of B7H3 and hsa-miR-214-3p in human breast cancer tissues and adjacent normal tissues were quantified using Western blotting and quantitative PCR (qPCR). experiments were performed to observe the effects of modulating the expression of B7H3 or hsa-miR-214-3p on breast cancer cell proliferation and apoptosis. Additionally, the regulatory impact of hsa-miR-214-3p on B7H3 was examined. Enzyme-linked immunosorbent assays (ELISA) and flow cytometry were employed to assess the effects of co-cultured breast cancer cells and normal human peripheral blood mononuclear cells (PBMCs) on immune cells and associated cytokines.Results:In breast cancer tissues, the expression level of B7H3 is inversely correlated with that of hsa-miR-214-3p, as well as with the regulatory effects on breast cancercell behavior. Hsa-miR-214-3p was found to inhibit breast cancer cell growth by downregulating B7H3. Importantly, our research identified, for the first time, two binding sites for hsa-miR-214-3p on the 3' uTR of B7H3, both of which exert similar effects independently. Co-culture experime

关键词： B7H3 Breast cancer Hsa-miR-214-3p Immunotherapy

Correction of failure in antenna array using matrix pencil technique

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Chinese Physics B 2017年第6期26卷 491-498页

作者： S u khan M K A Rahim Advanced Rf & Microwave Research Group Department of Communication Engineering Faculty of Electrical Engineering Universiti Teknologi Malaysia 81310 Skudai Johor Malaysia

In this paper a non-iterative technique is developed for the correction of faulty antenna array based on matrix pencil technique（MPT）. The failure of a sensor in antenna array can damage the radiation power pattern in terms of sidelobes level and nulls. In the developed technique, the radiation pattern of the array is sampled to form discrete power pattern information set. Then this information set can be arranged in the form of Hankel matrix（HM） and execute the singular value decomposition（SVD）. By removing nonprincipal values, we obtain an optimum lower rank estimation of HM. This lower rank matrix corresponds to the corrected pattern. Then the proposed technique is employed to recover the weight excitation and position allocations from the estimated matrix. Numerical simulations confirm the efficiency of the proposed technique, which is compared with the available techniques in terms of sidelobes level and nulls.

关键词： array correction low rank estimation matrix pencil technique singular value decomposition

Varying Track Etch Rates along the fission fragments＇ Trajectories in CR-39 Detectors

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Chinese Physics Letters 2010年第5期27卷 76-79页

作者： N. All E. u. khan A. Waheed S. Karim f. khan A. Majeed DPAM PLEAS P.O. Nilore Islamabad Pakistan P.D PINSTECH P.O. Nilore Islamabad Pakistan International Islamic university Islamabad Pakistan Department of Physics CIIT Islamabad Pakistan

We determine the behavior of track etch rate VT along the tracks in CR-39 detectors exposed to fission fragments from ^252Cf source. CR-39 detectors are etched at 70℃ in different concentrations of Na2COa-mixed 6M NaOH solutions for different etching time intervals of 5-10min starting from 15 min up to 210min. Two values of track etch rate are determined along the fission fragment trajectories. The variation in VT is correlated with the energy loss rate of the fission fragment in the detector material.

关键词： PARTICLE track etching NuCLEAR fission NuCLEAR fragmentation NuCLEAR track detectors TEMPERATuRE effect SODIuM compounds CORRELATION (Statistics) ENERGY dissipation

Swine flu pandemic:a global concern

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Asian Pacific Journal of Tropical Medicine 2010年第1期3卷 81-82页

作者： Asad u khan Interdisciplinary Biotechnology unit AMU Aligarh 202002 India

Recently WHO has again declared Influenza pandemic due to the outbreak of H1N1 which has infected over 254,206 people in 80 countries,with 625 *** lab has started working on the proteome analysis of H1N1,2009 out brea... 详细信息

关键词： Influenza A Virus Swine

On the detection of closed orbits in time-dependent systems by using double-pulse lasers

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Communications in Theoretical Physics 2020年第9期72卷 111-117页

作者： S u khan M L Du Institute of Theoretical Physics Chinese Academy of Sciences.Beijing 100190China university of Chinese Academy of Sciences Beijing100049China

In the photodetachment of atoms or negative ions by a double-pulse laser, the first pulse of the double-pulse laser generates waves and the delayed second pulse may detect them. The phenomenon of the excitation and detection of waves by a double-pulse laser can be used to identify the closed orbits in the system. We demonstrate this phenomenon with a negative hydrogen ion(H^-) by analyzing the total population excited by a double-pulse laser in a timedependent field for different physical parameters. By analyzing the total excited population using a double-pulse laser, we can uncover all the closed orbits existing in the system. We demonstrate that this can be realized by scanning the first pulse position and the time delay between the two pulses.

关键词： double-pulse laser detection of closed orbits photodetachment spectra time-dependent systems

Multiple drug resistance and bacterial infection

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Asian Pacific Journal of Tropical Medicine 2008年第2期1卷 76-82页

作者： Asad u khan Interdisciplinary Biotechnology unit Aligarh Muslim UniversityAligarh 202002India

Drug resistance is becoming a great problem in developing countries due to excessive use and misuse of antibiotics. The emergence of new pathogenic strains with resistance developed against most of the antibiotics which may cause,difficult to treat *** understand the current scenario in different mode of infection is most important for the clinicians and medical *** article summarized some common infections and antibiotic resistance pattern found among these pathogens.

关键词： Drug resistance Bacteria Infection

Cross Section of Heavy Ion Reaction （14.5 MeV/u） ^132Xe ＋ Bi

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Chinese Physics Letters 2006年第3期23卷 572-575页

作者： G. Sher M.I. Shahzad M. Hussain M. A. Rana E. u. khan Physics Research Division PINSTECH P.O Nilore Islamabad Pakistan Department of Physics University of the Punjab Lahore Pakistan

We investigate the cross section of the heavy ion reaction （14.5 MeV/u） ^132Xe ＋ Bi by using a CR-39 plastic track detector. The target-detector assembly is exposed at uNILAC beam facility of GSI, Germany. After etching under appropriate etching conditions, the detector is scanned for multipronged events produced as a result of interactions of projectile ions with target atoms. The elastic events are separated from binary events and used for the determination of the quarter-point angle. The quarter-point angle obtained is used to determine the total reaction cross section. The total experimental reaction cross section is determined by using statistics of inelastic events of two-pronged and higher multiplicity events. The experimental reaction cross sections determined by using elastic and inelastic data observed in the reaction under study are found to be in good agreement with the theoretically calculated value of reaction cross section using a sharp cutoff model.

关键词： SEQuENTIAL fISSION COuLOMB BARRIER TRACK DETECTORS NuCLEAR SCATTERING PB-208