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动漫界（幼教365） 2024年第25期 4-5页

作者： pe365研究院 pe365研究院

每天爸爸妈妈都会告诉毛毛喝水的重要性,可有一天毛毛想喝点特别的水。在尝试了各种特别的水后,毛毛的身体开始抗议了,他越来越虚弱,直到回家后喝了一杯普通的水。喝完水的毛毛发生了什么事情呢?一起走进绘本《我要喝有颜色的水》来看看吧!

关键词：绘本颜色重要性水

Threshold-Based Software-Defined Networking(SDN)Solution for Healthcare Systems against Intrusion Attacks

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Computer Modeling in Engineering & Sciences 2024年第2期138卷 1469-1483页

作者： Laila M.Halman Mohammed J.f.Alenazi Department of Computer Engineering College of Computer ScienceKing Saud UniversityRiyadh11451Saudi Arabia

The healthcare sector holds valuable and sensitive *** amount of this data and the need to handle,exchange,and protect it,has been increasing at a fast *** to their nature,software-defined networks(SDNs)are widely used in healthcare systems,as they ensure effective resource utilization,safety,great network management,and *** this sector,due to the value of thedata,SDNs faceamajor challengeposed byawide range of attacks,such as distributed denial of service(DDoS)and probe *** attacks reduce network performance,causing the degradation of different key performance indicators(KPIs)or,in the worst cases,a network failure which can threaten human *** can be significant,especially with the current expansion of portable healthcare that supports mobile and wireless devices for what is called mobile health,or *** this study,we examine the effectiveness of using SDNs for defense against DDoS,as well as their effects on different network KPIs under various *** propose a threshold-based DDoS classifier(TBDC)technique to classify DDoS attacks in healthcare SDNs,aiming to block traffic considered a hazard in the form of a DDoS *** then evaluate the accuracy and performance of the proposed TBDC *** technique shows outstanding performance,increasing the mean throughput by 190.3%,reducing the mean delay by 95%,and reducing packet loss by 99.7%relative to normal,with DDoS attack traffic.

关键词： Network resilience network management attack prediction software defined networking(SDN) distributed denial of service(DDoS) healthcare

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早起的一天

动漫界（幼教365） 2024年第1期 16-17页

作者： pe365研究院 pe365研究院

天还没亮,小珍珠就起床跟奶奶一起出门了,她们经过公园来到菜市场、花店,买了很多东西,做了一整天的准备。到了下午,爸爸妈妈、叔叔姑姑都回来了,大家欢聚一堂,是为了做什么呢?一起走进绘本《早起的一天》来揭晓答案吧!

关键词：绘本菜市场早起

Pathogenesis and clinical features of severe hepatitis E virus infection

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World Journal of Virology 2024年第2期13卷 19-33页

作者： László Orosz Károly Péter Sárvári Áron Dernovics András Rosztóczy Klára Megyeri Department of Medical Microbiology University of SzegedSzeged 6720Csongrád-CsanádHungary Department of Internal Medicine Division of GastroenterologyUniversity of SzegedSzeged 6725Csongrád-CsanádHungary

The hepatitis E virus(HEV),a member of the Hepeviridae family,is a small,non-enveloped icosahedral virus divided into eight distinct genotypes(HEV-1 to HEV-8).Only genotypes 1 to 4 are known to cause diseases in *** 1 and 2 commonly spread via fecal-oral transmission,often through the consum-ption of contaminated *** 3 and 4 are known to infect pigs,deer,and wild boars,often transferring to humans through inadequately cooked *** hepatitis caused by HEV in healthy individuals is mostly asymptomatic or associated with minor symptoms,such as ***,in immunosup-pressed individuals,the disease can progress to chronic hepatitis and even escalate to *** pregnant women,an HEV infection can cause fulminant liver failure,with a potential mortality rate of 25%.Mortality rates also rise amongst cirrhotic patients when they contract an acute HEV infection,which can even trigger acute-on-chronic liver failure if layered onto pre-existing chronic liver *** the prevalence of HEV infection continues to rise worldwide,highlighting the particular risks associated with severe HEV infection is of major medical *** text offers a brief summary of the characteristics of hepatitis developed by patient groups at an elevated risk of severe HEV infection.

关键词： Hepatitis E virus Cirrhosis Acute-on-chronic liver failure Pregnancy Immune dysfunction Open reading frames 1-4

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我爸爸

动漫界（幼教365） 2024年第33期 18-19页

作者： pe365研究院 pe365研究院

在每个孩子的心目中,爸爸是最棒的,也是最勇敢的。可是,想让宝宝说出爸爸棒在什么地方,又有哪些勇敢之处,很困难。不过,英国作家安东尼•布朗有办法,他将爸爸的形象用一个又一个生动有趣的比喻表现出来,形象易懂。让我们翻开绘本《我爸爸... 详细信息

在每个孩子的心目中,爸爸是最棒的,也是最勇敢的。可是,想让宝宝说出爸爸棒在什么地方,又有哪些勇敢之处,很困难。不过,英国作家安东尼•布朗有办法,他将爸爸的形象用一个又一个生动有趣的比喻表现出来,形象易懂。让我们翻开绘本《我爸爸》,一起去寻找棒棒的爸爸吧!

关键词：绘本生动有趣安东尼宝宝勇敢爸爸

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我喜欢书

动漫界（幼教365） 2024年第14期 8-9页

作者： pe365研究院 pe365研究院

书的世界多姿多彩、趣味缤纷甚至千奇百怪,但如果我们找不到通往图书世界的路,也许就会错过很多美好的“风景”。而《我喜欢书》这本绘本则为我们指出了这样一条路,让我们跟着绘本里的小猩猩.

关键词：绘本图书喜欢多姿多彩

Asymmetric reversible structural switching of a diene coordination polymer promoted by UV-visible light

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Science China Chemistry 2024年第2期67卷 536-541页

作者： Yong Wang Qiaoqiao Zhang Yong-Yong Cao Qi Liu Brendan f.Abrahams Jian-Ping Lang College of Chemistry Chemical Engineering and MaterialsSoochow UniversitySuzhou215123China State Key Laboratory of Organometallic Chemistry Shanghai Institute of Organic ChemistryChinese Academy of SciencesShanghai200032China College of Biological Chemical Science and EngineeringJiaxing UniversityJiaxing314001China School of Chemistry University of MelbourneVictoria3010Australia

In natural and artificial systems,reversible reactions are commonly asymmetric with respect to the time scale and nature of the stimuli which drive the forward and backward *** applications for which switching behavior is required,it is desirable that the reversible reaction goes as close to symmetric as possible;however,such systems are ***,we report an example of ultraviolet(UV)-visible light-regulated asymmetric reversible structural switching involving a diene-based coordination polymer,CP1 and its monocyclobutane product,*** is possible to cycle at least ten times through a forward [2+2] photocycloaddition reaction and the reverse,photocleavage reaction.A single cycle can be completed within a few *** transformation is accompanied by fast and distinct fluorescence changes,arising from optimisation of the reaction *** functional theory calculations allow rationalisation of the asymmetric reversible transformation between CP1 and CP1a rather than between CP1 and its dicyclobutane product *** work provides a clear illustration of reversible structural switching which approaches symmetric behaviour with respect to reaction rate and *** insights gained from this work also assist in the design of fast,reversible switching materials.

关键词： asymmetrical reversible structural switching coordination polymer photocycloaddition UV-visible light-controlled fluorescence switching

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太棒了,我们的职业

动漫界（幼教365） 2024年第18期 4-5页

作者： pe365研究院 pe365研究院

阿尔贝托和迪阿娜是学校的两位老师,今天,他们要讲各种各样的职业和职业领域。世界上的职业多得数不清,两位老师建议孩子们选一个自己感兴趣的职业聊一聊。孩子们会选择哪些职业呢?让我们翻开绘本,看一看吧!

关键词：绘本老师阿尔贝托职业感兴趣学校看一看

Omics-based biomarkers as useful tools in metabolic dysfunctionassociated steatotic liver disease clinical practice:How far are we?

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World Journal of Gastroenterology 2024年第14期30卷 1982-1989页

作者： Julieta Trinks María f Mascardi Adrián Gadano Sebastián Marciano Instituto de Medicina Traslacional e Ingeniería Biomédica-Consejo Nacional de Investigaciones Científicas y Técnicas-Instituto Universitario del Hospital Italiano-Hospital Italiano de Buenos Aires Ciudad Autónoma de Buenos Aires C1199ACLArgentina Consejo Nacional de Investigaciones Científicas y Técnicas Ciudad Autónoma de Buenos Aires C1425FQBArgentina Liver Unit Hospital Italiano de Buenos AiresCiudad Autónoma de Buenos Aires C1199DFArgentina Department of Research Hospital Italiano de Buenos AiresCiudad Autónoma de Buenos Aires C1199DFArgentina

Unmet needs exist in metabolic dysfunction-associated steatotic liver disease(MASLD)risk *** ability to identify patients with MASLD with advanced fibrosis and at higher risk for adverse outcomes is still *** novel biomarkers could represent a meaningful improvement to current risk *** this aim,omics technologies have revolutionized the process of MASLD biomarker discovery over the past *** the research in this field is thriving,much of the publication has been haphazard,often using single-omics data and specimen sets of convenience,with many identified candidate biomarkers but lacking clinical validation and *** we incorporate these biomarkers to direct patients’management,it should be considered that the roadmap for translating a newly discovered omics-based signature to an actual,analytically valid test useful in MASLD clinical practice is rigorous and,therefore,not easily *** article presents an overview of this area’s current state,the conceivable opportunities and challenges of omics-based laboratory diagnostics,and a roadmap for improving MASLD biomarker research.

关键词： Metabolic dysfunction-associated steatotic liver disease Non-alcoholic steatohepatitis Biomarker Risk stratification Omics

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牙齿大街的新鲜事

动漫界（幼教365） 2024年第35期 20-21页

作者： pe365研究院 pe365研究院

牙齿大街住着哈克和迪克两兄弟,这两个小东西看起来古灵精怪,其实是两个野心勃勃的危险分子--他们在牙齿大街挖洞建房,贮藏粮食,他们不仅要修建自己的舒适小窝,还梦想着修建可以出租的豪华公寓……就在他们的梦想快要实现的时候,很多警... 详细信息

牙齿大街住着哈克和迪克两兄弟,这两个小东西看起来古灵精怪,其实是两个野心勃勃的危险分子--他们在牙齿大街挖洞建房,贮藏粮食,他们不仅要修建自己的舒适小窝,还梦想着修建可以出租的豪华公寓……就在他们的梦想快要实现的时候,很多警察出现在牙齿大街上,紧接着,一个巨大的钩子从天而降,伸向了哈克和迪克的家……哈克和迪克的命运将会怎样呢?那些警察是从哪里来的呢?牙齿大街还能恢复往日的平静吗?让我们一起来读一读《牙齿大街的新鲜事》吧!

关键词：哈克古灵精怪牙齿警察