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数学译林 2015年第3期34卷 285-288,217页

作者： Valerio de angelis 陆柱家陈凌宇

1．引言对于阶乘函数n!的完全渐进展开——我们称其为Stirling（斯特林）级数，我们提出一个简洁和初等的推导．对于Stirling级数及由Stirling公式（见[3],[2],[4],[1]）

关键词：级数 Stirling公式渐进展开斯特林函数阶乘

Liver resection vs radiofrequency ablation in single hepatocellular carcinoma of posterosuperior segments in elderly patients

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World Journal of Gastrointestinal Surgery 2021年第12期13卷 1696-1707页

作者： Antonella delvecchio Riccardo Inchingolo Rita Laforgia francesca Ratti Maximiliano Gelli Massimiliano ferdinando Anelli Alexis Laurent Giulio Vitali Paolo Magistri Giacomo Assirati Emanuele felli Taiga Wakabayashi Patrick Pessaux Tullio Piardi fabrizio di Benedetto Nicola de'angelis Javier Briceño Antonio Rampoldi RenèAdam Daniel Cherqui Luca Antonio Aldrighetti Riccardo Memeo Unit of General Surgery "A.Perrino"HospitalCeglie Messapica 70124BariItaly Interventional Radiology Unit "F.Miulli"General Regional HospitalAcquaviva delle Fonti 75100Italy Unit of Laparoscopic Surgery University of BariBary 70124Italy Unit of Hepato-Pancreatic-Biliary Surgery University Vita Salute San RaffaeleMilan 20132Italy department of Surgical Oncology Gustave Roussy Cancer Campus Grand ParisVillejuif 94800France of General Surgery Reina Sofia University HospitalCordoba 14004Spain department of Digestive and Hepatobiliary Surgery Henry Mondor University HospitalCreteil 94000France Division of Transplantation Geneva University HospitalGeneva 44041Switzerland Hepato-Pancreato-Biliary Surgery and Liver Transplantation Unit University of Modena and Reggio EmiliaModena 42121Italy department of Digestive Surgery Strasbourg University HospitalStrasbourg 67000France department of Digestive and Hepatobiliary Surgery Robert DebrèUniversity HospitalReims 51100France Unit of Minimally Invasive and Robotic Digestive Surgery "F.Miulli"General Regional HospitalAcquaviva delle Fonti 70124Italy Interventional Radiology Unit Niguarda HospitalMilan 20162Italy department of Hepatobiliary Surgery Paul Brousse University HospitalVillejuif 94800France department of Hepatobiliary Surgery University Vita Salute San RaffaeleMilan 20132Italy Unit of Hepato-Pancreatic-Biliary Surgery "F.Miulli"General Regional HospitalAcquaviva delle Fonti 70124Italy

BACKGROUND Liver resection and radiofrequency ablation are considered curative options for hepatocellular *** choice between these techniques is still controversial especially in cases of hepatocellular carcinoma affecting posterosuperior segments in elderly *** To compare post-operative outcomes between liver resection and radiofrequency ablation in elderly with single hepatocellular carcinoma located in posterosuperior *** A retrospective multicentric study was performed enrolling 77 patients age≥70-years-old with single hepatocellular carcinoma(≤30 mm),located in posterosuperior segments(4a,7,8).Patients were divided into liver resection and radiofrequency ablation groups and preoperative,peri-operative and long-term outcomes were retrospectively analyzed and compared using a 1:1 propensity score *** After propensity score matching,twenty-six patients were included in each *** time and overall postoperative complications were higher in the resection group compared to the ablation group(165 min vs 20 min,Pficantly longer in the resection group than in the ablation group(7.5 d vs 3 d,Pficant differences between resection and ablation group in terms of overall survival and disease free survival at 1,3,and 5 *** Radiofrequency ablation in posterosuperior segments in elderly is safe and feasible and ensures a short hospital stay,better quality of life and does not modify the overall and disease-free survival.

关键词： Elderly Hepatocellular carcinoma Posterosuperior segments Liver resection Radiofrequency ablation Multicentric study

Anthocyanins from purple corn affect gut microbiota and metabolome in inflammatory bowel disease patients under infliximab infusion: the SiCURA pilot study

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food Science and Human Wellness 2024年第6期13卷 3536-3543页

作者： Mirco Vacca Eduardo Maria Sommella Marina Liso Giulio Verna Aurelia Scarano Annamaria Sila Margherita Curlo Mauro Mastronardi Katia Petroni Chiara Tonelli Bruno Di Jeso Angelo Santino Vincenzo Vestuto fabrizio Merciai Gianluigi Giannelli Pietro Campiglia Maria de angelis Marcello Chieppa francesco Maria Calabrese department of Soil Plant and Food ScienceUniversity of Bari Aldo MoroBari 70126Italy department of Pharmacy School of PharmacyUniversity of SalernoFisciano 84084Italy functional Gastrointestinal Disorders Research Group National Institute of Gastroenterology IRCCS“S.de Bellis”Castellana Grotte 70013Italy department of Medicine Digestive Health Research InstituteCase Western Reserve University School of MedicineCleveland 44106USA Unit of Lecce Institute of Sciences of Food Production C.N.R.Lecce 73100Italy department of Biosciences University of MilanMilan 20133Italy department of Biological and Environmental Sciences and Technologies University of SalentoLecce 73100Italy department of Biological and Environmental Sciences and Technologies(DISTEBA) University of SalentoLecce 73100Italy

Nowadays,inflammatory bowel disease(IBD)-patient therapies are mainly based on corticosteroid,thiopurine,and immunomodulator *** with active disease,that do not respond to corticosteroid and/or thiopurine treatment,can switch to the usage of the chimeric monoclonal antibody infliximab(IfX).However,to date,no treatment appeared to be conclusive in lowering the incidence of IBD *** the aim to increase the effectiveness of IfX treatment,we combined it with an adjuvant purple corn supplementation enriched in ***-patients were enrolled before they underwent to the IfX-infusion,and they were allocated in 2 different study *** in the intervention-arm followed a dietary supplementation with purple corn water-soluble extract,whereas control patients had a daily consumption of red fruit tea.16S rDNA gene-sequencing and high-resolution mass-spectrometry metabo-lipidomics analyses were conducted on stool and sera samples,*** a result,the experimental intervention mainly affected the serum metabolome of IBD-patients by decreasing the concentration of specific *** on IBD patient annotated taxa,a significant decrease in Lactobacillus and Bifi dobacterium relative abundances was *** far as it concerns the ulcerative colitis patient subset,the experimental intervention led to a decrease in Alistipes and Erysipelotrichaceae UCG-003 genus abundances and a concomitant Parabacteroides *** the contrary,after treatment,Crohn’s disease patients did not exhibit metataxonomics differences at the genus *** the end of the treatment that led to a reshaped microbiota community,the gathered data paves the way for the usage of a specifically designed probiotic supplementation as a valuable strategy for IBD-patients under IfX infusion.

关键词： Inflammatory bowel disease infliximab infusion Antioxidants Nutrigenomics Adjuvant therapy

可扩张聚酯硅酮覆膜支架的暂时置入治疗难治性良性食管狭窄

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世界核心医学期刊文摘（胃肠病学分册） 2005年第5期1卷 18-19页

作者： Repici A. Conio M. de angelis C. 翟惠虹

Background: Benign, refractory esophageal strictures are an important therapeutic challenge. Metal stents occasionally have been used, but results have been disappointing. The present study assessed the safety and the efficacy of temporary placement of the new expandable polyester silicone-covered stent for management of problematic esophageal strictures. Methods: fifteen patients with benign esophageal strictures were treated by temporary (6 weeks) placement of an expandable polyester silicone-covered stent. All patients had previously been treated, unsuccessfully, by repetitive endoscopic dilation. Results: Stent placement was successful in all patients. There was no procedure-related complication. Dilation with over-the-guidewire polyvinyl dilators was required before stent placement. With the stent in situ, dysphagia completely resolved in all patients. Six weeks after placement, one stent was found to have migrated into the stomach. In the remaining patients, the stent was easily removed with a foreign body forceps. The pretreatment dysphagia score was 3 (range 24); the post-treatment score was 1 (range 0-1) (p follow-up 22.7 [2.6] months) of the stricture was achieved in 12 patients (80%). The treatment failed in 3 patients, all of whom continue to require periodic dilation. Conclusions: In patients with benign esophageal strictures refractory to conventional dilation, temporary placement of a removable expandable polyester silicone-covered stent may lead to long-term relief of dysphagia with minimal morbidity.

关键词：食管狭窄覆膜支架性良扩张术扩张器吞咽困难金属支架令人

Impact of body mass index in elderly patients treated with laparoscopic liver resection for hepatocellular carcinoma

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World Journal of Gastrointestinal Surgery 2023年第1期15卷 72-81页

作者： Maria Conticchio Riccardo Inchingolo Antonella delvecchio francesca Ratti Maximiliano Gelli Massimiliano ferdinando Anelli Alexis Laurent Giulio Cesare Vitali Paolo Magistri Giacomo Assirati Emanuele felli Taiga Wakabayashi Patrick Pessaux Tullio Piardi fabrizio di Benedetto Nicola de’angelis Javier Briceño Antonio Rampoldi RenèAdam Daniel Cherqui Luca Antonio Aldrighetti Riccardo Memeo Unit of Hepato-Pancreatic-Biliary Surgery “F.Miulli”Regional General HospitalBari 70021Italy Interventional Radiology Unit “F.Miulli”Regional General HospitalBari 70021Italy Unit of Hepatobiliary Surgery San Raffaele HospitalMilano 20132Italy departement de Chirurgie Viscérale Gustave Roussy Cancer Campus Grand ParisParis 94800France Unit of Oncologic and Pancreatic Surgery Hospital University Reina SofíaCordoba 14004Spain Assistance Publique-Hôpitaux de Paris Department of Digestive and Hepatobiliary SurgeryCentre Hospitalier Universitaire Henri MondorCréteilParis 94000France Service of Abdominal Surgery Poliambulanza FoundationBrescia 25124Italy Hepato-Pancreato-Biliary Surgery and Liver Transplantation Unit University of Modena and Reggio EmiliaModena 41121Italy Institut de Recherche Contre les Cancers de l’Appareil Digestif(IRCAD) Strasbourg 67000France Service de Chirurgie Viscérale et Digestive Nouvel Hôpital CivilStrasbourg 67000France department of Surgery Hôpital Robert DebréReims 51092France Interventional Radiology Unit Niguarda HospitalMilan 20162Italy department of Surgery Centre HepatobiliaireHopital Paul BrousseParis 94000France

BACKGROUND The impact of obesity on surgical outcomes in elderly patients candidate for liver surgery is still *** To evaluate the impact of high body mass index(BMI)on perioperative and oncological outcome in elderly patients(>70 years old)treated with laparoscopic liver resection for hepatocellular carcinoma(HCC).METHODS Retrospective multicenter study including 224 elderly patients(>70 years old)operated by laparoscopy for HCC(196 with a BMIfrom January 2009 to January *** After propensity score matching,patients in two groups presented comparable results,in terms of operative time(median range:200 min vs 205 min,P=0.7 respectively in non-obese and obese patients),complications rate(22%vs 26%,P=1.0),length of hospital stay(median range:4.5 d vs 6.0 d,P=0.1).There are no significant differences in terms of short-and long-term postoperative *** The present study showed that BMI did not impact perioperative and oncologic outcomes in elderly patients treated by laparoscopic resection for HCC.

关键词： Hepatocellular carcinoma Body mass index Laparoscopy Surgical resection Elderly patients Propensity score matching

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采用新型风扇的高性能计算机

现代制造 2007年第31期 50-51页

作者： Walter angelis

高性能计算机JUBL是运算速度最快的计算机。然而,它对能源的供给提出了更高的要求。比如必须有效地为上千个处理器散热。一个特殊的通风方案是通过电子控制的对角线风扇输送冷风,实现电脑的顺利运行。

关键词：高性能计算机风扇运算速度电子控制通风方案处理器对角线散热

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^(183)Au核高自旋态转动带结构研究

高能物理与核物理 2005年第8期29卷 736-740页

作者：宋立涛周小红张玉虎郭应祥雷相国郑勇柳敏良 G.de angelis N.Marginean A.Gadea D.R.Napoli M.Axiotis C.Rusu T.Martinez 中国科学院近代物理研究所 Istituto Nazionale di fisisca Nuclear Laboratori Nazionali di LegnaroItaly

通过重离子熔合蒸发反应和在束核谱学实验方法研究了奇A核183Au的高自旋态能级结构.扩展并更新了183Au的能级纲图.首次建立了183Au的πi13/2转动带的能量非优先带.分析并讨论了183Au中πh9/2转动带的能量非优先带和πf7/2转动带间的相... 详细信息

通过重离子熔合蒸发反应和在束核谱学实验方法研究了奇A核183Au的高自旋态能级结构.扩展并更新了183Au的能级纲图.首次建立了183Au的πi13/2转动带的能量非优先带.分析并讨论了183Au中πh9/2转动带的能量非优先带和πf7/2转动带间的相互作用.

关键词： ^183Au核高自旋态转动带能级纲图重离子

further investigation on the fusion of ^(6)Li with ^(209)Bi target at near-barrier energies

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Chinese Physics C 2024年第7期48卷 106-117页

作者：张高龙焦振威张广鑫 M.R.Cortes 胡世鹏钱建强 D.Mengoni 屈卫卫李聪博郑云张焕乔孙慧斌王楠张春雷 J.J.Valiente-Dobón D.Testov M.Mazzocco A.Gozzelino C.Parascandolo D.Pierroutsakou M.La Commara A.Goasduff D.Bazzacco D.R.Napoli f.Galtarossa f.Recchia A.Illana S.Bakes I.Zanon S.Aydin G.de angelis M.Siciliano R.Menegazzo S.M.Lenzi J.L.ferreira J.Rangel Serkan Akkoyun L.f.Canto J.Lubian School of Physics Beihang UniversityBeijing 100191China Sino-french Institute of Nuclear Engineering and Technology Sun Yat-Sen UniversityZhuhai 519082China Instituto de física Universidade Federal Fluminense24210-340NiteróiRio de JaneiroBrazil Institute for Advanced Study in Nuclear Energy&Safety Shenzhen UniversityShenzhen 518060China Shenzhen Key Laboratory of Research and Manufacture of High Purity Germanium Materials and fetectors Shenzhen UniversityShenzhen 518060China INfN Sezione di PadovaPadovaItaly Dipartimento di fisica Astronomia dell'Universita di padova PadovaItaly State Key Laboratory of Radiation Medicine and Protection School of Radiation Medicine and ProtectionSoochow UniversitySuzhou 215123China China Institute of Atomic Energy Beijing 102413China The Key Laboratory of Beam Technology and Material Modification of Ministry of Education College of Nuclear Science and TechnologyBeijing Normal UniversityBeijing 100875China INfN Laboratori Nazionali di LegnaroI-35020 LegnaroItaly INfN Sezione di NapoliI-80126 NapoliItaly Dipartimento di farmacia Universitàdi Napoli"Federico II"I-80131 NapoliItaly department of Natural and Mathematical Sciences Faculty of EngineeringTarsus University33480 MersinTurkiye Physics Division Argonne National LaboratoryLemont-ILUSA departamento de Matemaética Física e Computaç˜ao Universidade do Estado do Rio de JaneiroFaculdade de Tecnologia27537-000ResendeRio de JaneiroBrazil department of Physics Sivas Cumhuriyet UniversitySivasTurkey Instituto de física Universidade Federal do Rio de JaneiroCP 6852821941-972Rio de JaneiroBrazil

The complete and incomplete fusion cross sections for ^(6)Li+^(209)Bi were measured using the in-beamγ-ray method around the Coulomb *** cross sections of.deuteron captured)incomplete fusion(ICf)products were re-quantified experimentally for this reaction *** results reveal that the ICf cross section is equivalent to that of complete fusion(Cf)above the Coulomb barrier and dominant near or below the Coulomb barrier.A theoretical calculation based on the continuum discretized coupled channel(CDCC)method was performed for the aforementioned Cf and ICf cross sections;the result is consistent with the *** universal fusion function(Uff)was also compared with the measured Cf cross section for different barrier parameters,demonstrating that the Cf suppression factor is significantly influenced by the choice of potential,which can reflect both dynamic and static effects of breakup on the fusion process.

关键词： cross section incomplete fusion suppression factor weakly bound nuclei

Time-of-flight methodologies with large-area diamond detectors for ion characterization in laser-driven experiments

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High Power Laser Science and Engineering 2022年第1期10卷 53-63页

作者： M.Salvadori G.Di Giorgio M.Cipriani M.Sciscio C.Verona P.L.Andreoli G.Cristofari R.de angelis M.Pillon N.E.Andreev P.Antici N.G.Borisenko D.Giulietti M.Migliorati O.Rosmej S.Zahter f.Consoli fusion and Nuclear Safety department ENEAFrascatiItaly INRS-EMT VarennesQCCanada Industrial Engineering department University of Rome"Tor Vergata"RomeItaly Joint Institute for High Temperatures RASMoscowRussia P.N.Lebedev Physical Institute RASMoscowRussia department of Physics University of PisaPisaItaly INfN of Pisa PisaItaly University of Rome“La Sapienza” RomeItaly INfN of Rome RomeItaly GSI Helmotzzentrum fur Schwerionenforschung GmbH DarmstadtGermany Goethe University frankfurt FrankfurtGermany

The time-of-flight technique coupled with semiconductor detectors is a powerful instrument to provide real-time characterization of ions accelerated because of laser-matter ***,the presence of strong electromagnetic pulses(EMPs)generated during the interactions can severely hinder its *** this reason,the diagnostic system must be designed to have high EMP *** we present a new advanced prototype of.detector,developed at ENEA-Centro Ricerche frascati(Italy),with a large-area(15 mm×15 mm)polycrystalline diamond sensor having 150 μm *** tailored detector design and testing ensure high sensitivity and,thanks to the fast temporal response,high-energy resolution of the reconstructed ion *** detector was offline calibrated and then successfully tested during an experimental campaign carried out at the PHELIX laser facility(E_(L)~100 J,τ_(L)=750 fs,I_(L)(1-2.5)×10^(19)W/cm^(2))at GSI(Germany).The high rejection to EMP fields was demonstrated and suitable calibrated spectra of the accelerated protons were obtained.

关键词： diamond detector ion diagnostics laser-matter interaction time of flight

Peri-operative score for elderly patients with resectable hepatocellular carcinoma

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World Journal of Hepatology 2023年第12期15卷 1307-1314页

作者： Maria Conticchio Riccardo Inchingolo Antonella delvecchio francesca Ratti Maximiliano Gelli Massimiliano ferdinando Anelli Alexis Laurent Giulio Cesare Vitali Paolo Magistri Giacomo Assirati Emanuele felli Taiga Wakabayashi Patrick Pessaux Tullio Piardi fabrizio di Benedetto Nicola de'angelis Javier Briceño Antonio Rampoldi RenèAdam Daniel Cherqui Luca Antonio Aldrighetti Riccardo Memeo Unit of Hepato-Pancreatic-Biliary Surgery “F.Miulli”Regional General HospitalAcquaviva Delle Fonti 70021Italy Interventional Radiology Unit Department of Radiology“F.Miulli”Regional General HospitalAcquaviva Delle Fonti 75100Italy Hepatobiliary Surgery Division IRCSS San Raffaele Scientific InstituteMilan 20132Italy Hepatobiliary Surgery Division Vita-Salute San Raffaele UniversityMilan 20132Italy Département de Chirurgie Viscérale Gustave Roussy Cancer Campus Grand ParisParis 94800France Unit of Oncologic and Pancreatic Surgery Hospital University Reina SofíaCordoba 14004Spain department of Digestive and Hepatobiliary Surgery Assistance Publique-Hôpitaux de ParisCréteil 94000France Service of Abdominal Surgery Poliambulanza FoundationBrescia 25124Italy Hepato-Pancreato-Biliary Surgery and Liver Transplantation Unit University of Modena and Reggio EmiliaModena 41121Italy department of Surgery Institut de Recherche Contre les Cancers de l'Appareil Digestif(IRCAD)Strasbourg 67000France Service de Chirurgie Viscérale et Digestive Nouvel Hôpital CivilUnitéINSERM U1110Strasbourg 67000France department of Surgery Hôpital Robert DebréReims 51092France Assistance Publique-Hôpitaux de Paris Centre Hospitalier Universitaire Henri MondorParis 94000France Unit of Hepatobiliary Surgery and Liver Transplantation Hospital University Reina SofíaCordoba 14004Spain Interventional Radiology Unit Niguarda HospitalMilan 20162Italy department of Surgery Centre HepatobiliaireHopital Paul BrousseParis 94000France

BACKGROUND Liver resection is the mainstay for a curative treatment for patients with resectable hepatocellular carcinoma(HCC),also in elderly *** this,the evaluation of patient condition,liver function and extent of disease remains a demanding process with the aim to reduce postoperative morbidity and *** To identify new perioperative risk factors that could be associated with higher 90-and 180-d mortality in elderly patients eligible for liver resection for HCC considering traditional perioperative risk scores and to develop a risk *** A multicentric,retrospective study was performed by reviewing the medical records of patients aged 70 years or older who electively underwent liver resection for HCC;several independent variables correlated with death from all causes at 90 and 180 d were *** coefficients of Cox regression proportional-hazards model for sixmonth mortality were rounded to the nearest integer to assign risk factors'weights and derive the scoring *** Multivariate analysis found variables(American Society of Anesthesiology score,high rate of comorbidities,Mayo end stage liver disease score and size of biggest lesion)that had independent correlations with increased 90-and 180-d mortality.A clinical risk score was developed with survival *** This score can aid in stratifying this population in order to assess who can benefit from surgical treatment in terms of postoperative mortality.

关键词： Hepatocellular carcinoma Score Laparoscopy Surgical resection Elderly patients Multivariate analysis