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国际医学放射学杂志 2018年第4期 476-476页

作者： M.Occhipinti M.Paoletti f.bigazzi G.Camiciottoli R.Inchingolo A.R.Larici 朱静 Department of Experimental and Clinical Medicine University of FlorenceCareggi University Hospital

目的通过区分气肿性和非气肿性总气体滞留,来确定在慢性阻塞性肺疾病(COPD)病人中广泛应用的CT表现类型。通过临床数据对气肿性气体滞留进行预测与分级。材料与方法前瞻性研究了202例符合条件病人(男159例,女43例,年龄41～85岁,平均70岁... 详细信息

目的通过区分气肿性和非气肿性总气体滞留,来确定在慢性阻塞性肺疾病(COPD)病人中广泛应用的CT表现类型。通过临床数据对气肿性气体滞留进行预测与分级。材料与方法前瞻性研究了202例符合条件病人(男159例,女43例,年龄41～85岁,平均70岁)。病人肺功能及CT数据由呼吸科和放射科医师提供。在吸气末和呼气末时进行非对比增强胸部CT扫描,并定量分析。CT参数设置为:120 k V,200 m As,旋转时间0.5 s,螺距1.1,层厚0.75 mm,重建核b31f和b70f。通过吸气和呼气CT密度阈值差获得气体滞留(CT衰减值<-950 HU的百分比面积和CT衰减值<-856 HU的百分比面积)并与配准分析得到的结果进行比较。基于人体测量学和功能数据对logistic回归模型进行交叉验证,并根据CT评估的肺气肿对总气体滞留的相对作用对COPD病人进行分类。结果通过吸气和呼气CT密度阈值差得到的气体滞留与经配准分析得到的气体滞留高度相关(r=0.99)。病人根据CT表现类型分为4组:弥漫性气肿性气体潴留、弥漫性功能性气体潴留、重度混合性和轻度混合性。预测模型包括1 s用力呼气量/肺活量、1 s用力呼气量、一氧化碳扩散量百分比、体质量指数作为CT肺气肿的回归因子,根据其程度对病人进行分类可以达到81%的总体准确度。结论 CT吸气和呼气密度阈值差能够准确确定由吸气和呼气配准CT扫描得到的气肿性和非气肿性气体滞留的相对作用,且通过肺功能数据和身体质量指数可准确预测适用于临床目的的肺气肿CT范围。

关键词：肺气肿气体滞留慢性阻塞性肺疾病肺功能 CT

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慢性阻塞性肺疾病:肺功能和CT值不呈线性相关

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国际医学放射学杂志 2015年第5期 486-486页

作者： M.Paoletti L.Cestelli f.bigazzi G.Camiciottoli M.Pistolesi 罗厚丽 Department of Experimental and Clinical Medicine University of Florence

摘要目的与传统的单因素和多因素统计方法评估相比,探讨多模型估计法在慢性阻塞性肺疾病(COPD)中肺功能和CT值的相关性是否具有更高的准确性。材料与方法本研究经伦理委员会批准。所有参与者均签署了知情同意书。采用单因素和多因素统... 详细信息

摘要目的与传统的单因素和多因素统计方法评估相比,探讨多模型估计法在慢性阻塞性肺疾病(COPD)中肺功能和CT值的相关性是否具有更高的准确性。材料与方法本研究经伦理委员会批准。所有参与者均签署了知情同意书。采用单因素和多因素统计模型法分析预测132例COPD病人吸气相肺CT值<-950 HU(%LAA-950insp)和呼气相肺

关键词：慢性阻塞性肺疾病肺功能 COPD CT

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Holographic Duals of Quark Gluon Plasmas with Unquenched flavors

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Communications in Theoretical Physics 2012年第3期57卷 364-386页

作者： francesco bigazzi Aldo Cotrone Javier Mas Daniel Mayerson Javier Tarrio Dipartimento di fisica e Astronomia Universita' di Firenze Via G.Sansone 1 I-50019 Sesto Fiorentino (Firenze)Italyand INFNSezione di PisaLargo B.Pontecorvo356127 PisaItaly Dipartimento di fisica Universita' di Torino and INFN Sezione di Torino Via P.Giuria 1 I-10125 TorinoItaly Departamento de f' sica de Part' culas Universidade de Santiago de Compostela and Instituto Galego de F' sica de Altas Enerx' as (IGFAE) E-15782 Santiago de CompostelaSpain Institute for Theoretical Physics University of AmsterdamScience Park 904Postbus 944851090 GL AmsterdamThe Netherlands Institute for Theoretical Physics Universiteit Utrecht3584 CEUtrechtThe Netherlands

We review the construction of gravitational solutions holographically dual to N=1 quiver gauge theories with dynamical flavor *** focus on the D3-D7 construction and consider the finite temperature,finite quark chemical potential case where there is a charged black hole in the dual *** physical outputs of the model include its thermodynamics (with susceptibilities) and general hydrodynamic properties.

关键词：夸克胶子等离子体全息口味淬灭水动力性能有限温度带电黑洞化学势

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Challenges of Improving Intensive Care Medicine in Eritrea: Impact of an Italian Cooperative Project of Educational and Clinical Support

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Open Journal of Anesthesiology 2013年第7期3卷 315-319页

作者： Valentina Anichini Giovanni Zagli Hagos Goitom Giovanni Cianchi Andrea Cecchi Lucia Perretta Emanuele bigazzi Barbara Gazzini Simone Proietti Alessandro Di filippo Simone Toccafondi Gianfranco Gensini Giancarlo Berni Adriano Peris Anesthesia and Intensive Care Unit of Emergency Department Careggi Teaching Hospital Florence Italy Anesthesia and Intensive Care Faculty of Medicine University of Florence Florence Italy Department Intensive Care Unit Orotta National Referral Hospital Asmara Eritrea Department of Critical Care Medicine and Surgery Careggi Teaching Hospital Florence Italy first Aid of Emergency Department Careggi Teaching Hospital Florence Italy Tuscany Region Sanitary System Florence Italy.

Intensive care in Africa is available only in teaching or referral hospitals. Here we report the experience of a multidisciplinary collaboration between physicians and nurses of the Emergency Department (first Aid and Intensive Care Unit) of a tertiary referral hospital (Careggi Teaching Hospital, florence, IT) and physicians and nurses of Orotta National referral Hospital in Asmara, Eritrea. The project was aimed at performing clinical assistance and training on the job to the local staff to improve the standard of care in the local Emergency Department. The duration of the project was initially planned to be 30 months, but unfortunately it was interrupted after 18 months because of lack of funds. The Italian staff was composed of two physicians and two nurses per period. To monitor local ICU activity, a retrospective survey of 36 months was performed. During the 36 months of data collection, 1169 patients were admitted to the ICU. Intra-ICU mortality rate resulted comparable before, during, and after Italian presence. On the contrary, the 28-day mortality resulted significantly lower bo th during and after the Italian stay. After project interruption, the Italian staff maintained contact with the Eritrean ICU personnel, who were invited to attend the Italian ICU for one month per year, and collected information about Orotta ICU activities.

关键词： Intensive Care Unit Developing Countries MEWS

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Management of unstable angina in a patient with Haemophilia A

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World Journal of Hematology 2017年第2期6卷 28-31页

作者： Andreina Carbone Tiziana formisano francesco Natale Maurizio Cappelli bigazzi Donato Tartaglione Enrica Golia felice Gragnano Mario Crisci Renato Maria Bianchi Raffaele Calabrò Maria Giovanna Russo Paolo Calabrò Chair of Cardiology Second University of NaplesAORN dei ColliMonaldi Hospital

Hemophilia A is an X-linked recessive disorder characterized by a deficiency of coagulation factor Ⅷ(fⅧ) and therefore by a greater risk of bleeding during percutaneous interventional procedures and during the dual antiplatelet therapy(DAPT) in patients with ischemic heart disease. Information regarding safe percutaneous procedures in hemophiliacs is limited. Since the introduction of fVⅧ concentrates, the life expectancy of hemophiliac patients has improved and consequently, the rate of ischemic heart disease in this population is increased. frequently the replacement therapy can trigger the onset of an acute coronary syndrome. We report a case of a patient with mild Hemophilia A, who presents with unstable angina, treated successfully with coronary angioplasty and drug eluting stent implantation without replacement of fVⅧ, treated with long term DAPT without major bleeding after six months of follow up.

关键词： Hemophilia A Unstable angina Dual antiplatelet therapy Drug eluting stent Coagulation factors replacement therapy

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