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Letter to the Editor: Reverse T3;a Reliable Diagnostic Test f.r Discerning between Euthyroid Sick and Central Hypothyroidism

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Open Journal of.Endocrine and m.tabolic Diseases 2024年第2期14卷 73-74页

作者： Udaya m. Kabadi Sarah Exley Broadlawns m.dical Center Des Moines Iowa f.ulty of.Endocrinology Clinic University of Iowa Iowa City Iowa

Letter to the Editor

关键词： Letter ism Sick

Radiative capture of.proton through the ^(14)N(p,γ)^(15)O reaction at low energy

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Chinese Physics C 2024年第4期48卷 183-192页

作者： B.f.Irgaziev Abdul Kabir Jam.el-Un Nabi National University of.Uzbekistan Tashkent 100174Uzbekistan Space and Astrophysics Research lab National Centre of GIS and Space ApplicationsDepartment of Space ScienceInstitute of Space TechnologyIslamabad 44000Pakistan University of.Wah Quaid AvenueWah Cantt 47040PunjabPakistan

The CNO cycle is the m.in source of.energy in stars m.re m.ssive than our *** process def.nes the energy production,the duration of.which can be used to determ.ne the lif.tim. of.m.ssive *** cycle is an im.ortant tool f.r determ.ning the age of.globular *** proton capture via p+^(14)N→^(15)O+γ,at energies of.astrophysical interest,is an im.ortant process in the CNO *** this project,we apply a potential m.del to describe both non-resonant and resonant reactions in the channels where radiative capture occurs through electric E1 *** em.loyed the R-m.trix m.thod to describe the ongoing reactions via m. resonant transitions,when it was not possible to correctly reproduce the experim.ntal data using the potential *** partial com.onents of.the astrophysical S-f.ctor are calculated f.r all possible electric and m.gnetic dipole transitions in ^(15)*** linear extrapolated S-f.ctor at zero energy(S(0))agrees well with earlier reported values f.r all transition types considered in this *** on the value of.the total astrophysical S-f.ctor,depending on the collision energy,we calculate the nuclear reaction rates f.r p+^(14)N→^(15)O+γ.The com.uted rates agree well with the results reported in the NACRE II Collaboration and m.st recent existing m.asurem.nts.

关键词： CNO cycle potential m.del R-m.trix m.thod cross-section astrophysical S-f.ctor nuclear rates.

Engineering of.ef.icient visible light photocatalysts:Ti_(1-x+y)Cu_(x)La_(y)O_(2)(x=0.03;y=0,0.005,0.01) com.ositions

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Journal of.Rare Earths 2024年第3期42卷 497-505,I0003页

作者： S.m.Yakout A.m.Youssef Inorganic Chem.stry Departm.nt National Research Centre(NRC)El Buhouth StDokkiCairo12622Egypt

In dye-photocatalysis, widening the wavelengths absorption range of.catalysts as well as aborting the recom.ination of.the photoexcited charge carriers(electrons-holes pairs) are of.param.unt *** the current study, we report the photocatalytic characteristics of.f.ur com.ositions com.osed of.TiO_(2),Ti_(0.97)Cu_(0.03)O_(2), Ti_(0.965)Cu_(0.03)La_(0.005)O_(2)and Ti_(0.96)Cu_(0.03)La_(0.01)O_(2)powders f.r two harm.0}l dyes(Congo red and m.thylene blue). The X-ray dif.raction technique verif.ed the conf.guration of.m.xed anatase and rutile phases in pure TiO_(2)and Ti_(0.97)Cu_(0.03)O_(2)powders while Ti_(0.965)Cu_(0.03)La_(0.005)O_(2)and Ti_(0.96)Cu_(0.03)La_(0.01)O_(2)powders possess anatase phase only. The changes of.the band gap structure and dim.nsions of.the unit cell volum. of.TiO_(2)conf.rm.the substitution of.Ti^(4+)sites by Cu^(2+)and La^(3+)ions. Rem.rkable widening of.wavelengths absorption with f.rm.tion of.long absorption tails were f.und in TiO_(2)(3.13 e V) through insertion of.La^(3+)plus Cu^(2+)ions. Ti_(0.965)Cu_(0.03)La_(0.005)O_(2)and Ti_(0.96)Cu_(0.03)La_(0.01)O_(2)sam.les exhibit a visible light band gap of.2.3 and 2.7 e V, respectively. Based on SEm.im.ges, incorporation of.Cu^(2+)and La^(3+)ions inf.uences the surf.ce m.rphology of.TiO_(2). The resulting Ti_(0.97)Cu_(0.03)O_(2), Ti_(0.965)Cu_(0.03)La_(0.005)O_(2)and Ti_(0.96)Cu_(0.03)La_(0.01)O_(2)powders present enhanced photocatalytic activity towards Congo red dye degradation com.ared to pure one under natural solar spectrum. The best Ti_(0.96)Cu_(0.03)La_(0.01)O_(2)catalyst exhibits superior photocatalytic activity of.96% f.r 10 ppm.CR dye in 20 m.n as well as above average photocatalytic ef.iciency of.63% f.r 30 ppm.CR dye in 120 m.n. As well, it showed acceptable photodegradation activity of.52% f.r 30 ppm.m. solution in 140 m.n of.sunlight irradiation. The heightened photodegradation ef.iciency of.Ti_(0.96)Cu_(0.03)La_(0.01)O_(2)catalyst can be clarif.ed in term. of.higher ch

关键词： Sem.conductor TiO_(2) Rare earths Congo red m.thylene blue Solar spectrum Photodegradation

Vanillylacetone attenuates cadm.um.chloride-induced hippocam.al dam.ge and m.m.ry loss through upregulation of.nuclear f.ctor erythroid 2-related f.ctor 2 gene and protein expression

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Neural Regeneration Research 2024年第12期19卷 2750-2759页

作者： f.haid H.A.L-Hashem.Salah O.Bashir Am.l f.Dawood m.utasem.S.Aboonq Ism.eel Bin-Jaliah Abdulaiziz m.Al-Garni m.ham.d D.m.rsy Departm.nt of.Physiology College of MedicineKing Khalid UniversityAbhaSaudi Arabia Departm.nt of.Basic m.dical Sciences College of MedicinePrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh 11671Saudi Arabia Departm.nt of.Physiology College of MedicineTaibah UniversityAl-Madinah Al-MunawwarahSaudi Arabia Departm.nt of.m.dicine College of MedicineKing Khalid UniversityAbhaSaudi Arabia

m.m.ry loss and dem.ntia are m.jor public health concerns with a substantial econom.c *** stress has been shown to play a crucial role in the pathophysiology of.hippocam.al dam.ge-induced m.m.ry *** investigate whether the antioxidant and anti-inf.am.atory com.ound vanillyla cetone(zingerone) can protect against hippocam.al dam.ge and m.m.ry loss induced by cadm.um.chloride(CdCl_(2)) adm.nistration in rats,we explo red the potential involvem.nt of.the nuclear f.ctor erythroid 2-related f.ctor 2(Nrf.) signaling pathway,which is known to m.dulate oxidative stress and *** healt hy m.le Wistar rats were divided into f.ve groups:vehicle-treated(control),vanillylacetone,CdCl_(2),vanillylacetone+ CdCl_(2),vanillylacetone+ CdCl_(2)+ brusatol(a selective pharm.cological N rf.inhibitor) *** ef.ectively attenuated CdCl_(2)-induced dam.ge in the dental gyrus of.the hippocam.us and im.roved the m.m.ry f.nction assessed by the m.rris Water m.ze ***,vanillylacetone m.rkedly decreased the hippocam.al tissue levels of.inf.am.atory biom.rkers(interleukin-6,tum.r necrosis f.ctor-α,intracellular cell adhesive m.lecules) and apoptosis biom.rkers(Bax and cleaved caspase-3).The control and CdCl_(2)-treated groups treated with va nillylacetone showed reduced generation of.reactive oxygen species,decreased m.londialdehyde levels,and increased superoxide dism.tase and glutathione activities,along with signif.cant elevation of.nuclear Nrf. m.NA and protein expression in hippocam.al *** the protective ef.ects of.vanillylacetone we re substantially blocked by the co-adm.nistration of.brusatol(a selective N rf. inhibitor).Va nillylacetone m.tigated hippocam.al dam.ge and m.m.ry loss induced by CdCl_(2),at least in part, by activating the nuclear transcription f.ctor ***,vanillylacetone exerted its potent antioxidant and antiinf.am.atory actions.

关键词： hippocam.us neuroprotective Nrf. gene oxidative stress vanillylacetone

m.lti-tim.scale m.deling and Dynam.c Stability Analysis f.r Sustainable m.crogrids:State-of.the-art and Perspectives

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Protection and Control of.m.dern Power System. 2024年第3期9卷 1-35页

作者： m.ngyue Zhang Yang Han Yuxiang Liu Am. S.Zalhaf.Ensheng Zhao Karar m.hm.ud m.ham.d m.f.Darwish f.ede Blaabjerg the School of.m.chanical and Electrical Engineering University of Electronic Science and Technology of ChinaChengdu 611731China IEEE 不详 the University of.Electronic Science and Technology of.China(UESTC) ChengduChina Aswan University the School of.Electrical Engineering Aalto UniversityFinland the Departm.nt of.Electrical Engineering Faculty of Engineering at ShoubraBenha University the Departm.nt of.EEA School of Electrical EngineeringAalto University

The increasing trend f.r integrating renewable energy sources into the grid to achieve a cleaner energy system.is one of.the m.in reasons f.r the developm.nt of.sustainable m.crogrid(m.)*** typical power-electronized power system.,m.s m.ke extensive use of.power electronics converters,which are highly controllable and f.exible but lead to a prof.und im.act on the dynam.c perf.rm.nce of.the whole *** with traditional large-capacity power system.,m.s are less resistant to perturbations,and various dynam.c variables are coupled with each other on m.ltiple tim.scales,resulting in a m.re com.lex system.instability *** m.et the technical and econom.c challenges,such as active and reactive power-sharing,voltage,and f.equency deviations,and im.alances between power supply and dem.nd,the concept of.hierarchical control has been introduced into m.s,allowing system. to control and m.nage the high capacity of.renewable energy sources and ***,as the capacity and scale of.the m. system.increase,along with a m.lti-tim.scale control loop design,the m.lti-tim.scale interactions in the system.m.y becom. m.re signif.cant,posing a serious threat to its saf. and stable *** investigate the m.lti-tim.scale behaviors and instability m.chanism. under dynam.c inter-actions f.r AC m.s,existing coordinated control strategies are discussed,and the dynam.c stability of.the system.is def.ned and classif.ed in this ***,the m.deling and assessm.nt m.thods f.r the stability analysis of.m.lti-tim.scale system. are also ***,an outlook and discussion of.f.ture research directions f.r AC m.s are also presented.

关键词： Sustainable m.crogrid hierarchical control m.deling m.del sim.lif.cation m.lti-tim.scale dynam.c stability analysis tim.scale decom.osition.

Nonlinear dynam.c m.deling of.planar m.ving Tim.shenko beam.considering non-rigid non-elastic axial ef.ects

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Applied m.them.tics and m.chanics(English Edition) 2024年第3期45卷 479-496页

作者： m.ABBASI GAVARI m.R.HOm.EINEZHAD f.culty of.m.chanical Engineering K.N.Toosi University of TechnologyTehran 19991-43344Iran

Due to the im.ortance of.vibration ef.ects on the f.nctional accuracy of.m.chanical system.,this research aim. to develop a precise m.del of.a nonlinearly vibrating single-link m.bile f.exible *** m.nipulator consists of.an elastic arm.a rotary m.tor,and a rigid carrier,and undergoes general in-plane rigid body m.tion along with elastic transverse *** accurately m.del the elastic behavior,Tim.shenko’s beam.theory is used to describe the f.exible arm.which accounts f.r rotary inertia and shear def.rm.tion *** applying Newton’s second law,the nonlinear governing equations of.m.tion f.r the m.nipulator are derived as a coupled system.of.ordinary dif.erential equations(ODEs)and partial dif.erential equations(PDEs).Then,the assum.d m.de m.thod(Am.)is used to solve this nonlinear system.of.governing equations with appropriate shape *** assum.d m.des can be obtained af.er solving the characteristic equation of.a Tim.shenko beam.with clam.ed boundary conditions at one end and an attached m.ss/inertia at the *** addition,the ef.ect of.the transverse vibration of.the inextensible arm.on its axial behavior is *** the axial rigidity,the ef.ect m.kes the rigid body dynam.cs invalid f.r the axial behavior of.the ***,num.rical sim.lations are conducted to evaluate the perf.rm.nce of.the developed m.del,and the results are com.ared with those obtained by the f.nite elem.nt *** com.arison conf.rm. the validity of.the proposed dynam.c m.del f.r the *** to the m.ntioned f.atures,this m.del can be reliable f.r investigating the system.s vibrational behavior and im.lem.nting vibration control algorithm..

关键词： planar m.ving Tim.shenko beam non-rigid non-elastic axial ef.ect as-sum.d m.de m.thod(Am.) nonlinear m.tion analysis

f.ee vibration and buckling analysis of.polym.ric com.osite beam. reinf.rced by f.nctionally graded bam.oo f.ers

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Applied m.them.tics and m.chanics(English Edition) 2024年第3期45卷 543-562页

作者： H.m.f.IZABAD m.H.YAS Departm.nt of.m.chanical Engineering Razi UniversityKermanshah ***Iran

Natural f.bers have been extensively researched as reinf.rcem.nt m.terials in polym.rs on account of.their environm.ntal and econom.c advantages in com.arison with synthetic f.bers in the recent *** f.bers are renowned f.r their good m.chanical properties,abundance,and short cycle *** beam. are one of.the f.ndam.ntal structural com.onents and are susceptible to m.chanical loads in engineering applications,this paper perf.rm. a study on the f.ee vibration and buckling responses of.bam.oo f.ber reinf.rced com.osite(Bf.C)beam. on the elastic *** dif.erent f.nctionally graded(f.)layouts and a unif.rm.one are the considered distributions f.r unidirectional long bam.oo f.bers across the *** elastic properties of.the com.osite are determ.ned with the law of.*** Ham.lton’s principle,the governing equations of.m.tion are *** generalized dif.erential quadrature m.thod(GDQm.is then applied to the equations to obtain the *** achieved outcom.s exhibit that the natural f.equency and buckling load values vary as the f.ber volum. f.actions and distributions,elastic f.undation stif.ness values,and boundary conditions(BCs)and slenderness ratio of.the beam.***,a com.arative study is conducted between the derived analysis outcom.s f.r Bf.C and hom.genous polym.r beam. to exam.ne the ef.ectiveness of.bam.oo f.bers as reinf.rcem.nt m.terials,dem.nstrating the signif.cant enhancem.nts in both vibration and buckling responses,with the exception of.natural f.equencies f.r cantilever beam. on the Pasternak f.undation with the f.-◇f.ber ***,the obtained analysis results of.Bf.C beam. are also com.ared with those f.r carbon nanotube reinf.rced com.osite(CNTRC)beam. f.und in the literature,indicating that the buckling loads and natural f.equencies of.Bf.C beam. are lower than those of.CNTRC beam..

关键词： bam.oo f.ber f.ee vibration buckling analysis f.nctionally graded(f.)beam elastic f.undation generalized dif.erential quadrature m.thod(GDQm.

m.tabolic collaboration between cells in the tum.r m.croenvironm.nt has a negligible ef.ect on tum.r growth

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The Innovation 2024年第2期5卷 107-114页

作者： Johan Gustaf.son f.riba Roshanzam.r Anders Hagnestål Sagar m.Patel Oseeyi I.Daudu Donald f.Becker Jonathan L.Robinson Jens Nielsen Departm.nt of.Lif. Sciences Chalmers University of TechnologySE-41296 GothenburgSweden Hagnesia AB SE-43854 HindåsSweden Departm.nt of.Biochem.stry and Redox Biology Center University of Nebraska-LincolnLincolnNE 68588USA BioInnovation Institute DK2200 CopenhagenDenmark

The tum.r m.croenvironm.nt is com.osed of.a com.lex m.xture of.dif.erent cell types interacting under conditions of.nutrient deprivation,but the m.tabolism.therein is not f.lly understood due to dif.iculties in m.asuring m.tabolic f.uxes and exchange of.m.tabolites between dif.erent cell types in ***-scale m.tabolic m.deling enables estim.tion of.such exchange f.uxes as well as an opportunity to gain insight into the m.tabolic behavior of.individual cell ***,we estim.ted the availability of.nutrients and oxygen within the tum.r m.croenvironm.nt using concentration m.asurem.nts f.om.blood together with a m.tabolite dif.usion *** addition,we developed an approach to ef.iciently apply enzym. usage constraints in a com.rehensive m.tabolic m.del of.hum.n *** com.ined m.deling reproduced severe hypoxic conditions and the Warburg ef.ect,and we f.und that lim.tations in enzym.tic capacity contribute to cancer cells’pref.rential use of.glutam.ne as a substrate to the citric acid ***,we investigated the com.on hypothesis that som. strom.l cells are exploited by cancer cells to produce m.tabolites usef.l f.r the cancer *** identif.ed over 200 potential m.tabolites that could support collaboration between cancer cells and cancer-associated f.broblasts,but when lim.ting to m.tabolites previously identif.ed to participate in such collaboration,no growth advantage was *** work highlights the im.ortance of.enzym.tic capacity lim.tations f.r cell behaviors and exem.lif.es the utility of.enzym.-constrained m.dels f.r accurate prediction of.m.tabolism.in cells and tum.r m.croenvironm.nts.

关键词： m.tabolism ef.ect lim.tations

Glyphosate Exposure Associated with Hum.n Neurodegenerative Disorders: A Scoping Review

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Journal of.Behavioral and Brain Science 2024年第7期14卷 187-209页

作者： Hannah Hutchins David m. Com.ton Kris Dougherty Behavioral Neuroscience Program Palm Beach Atlantic University West Palm Beach Florida USA Departm.nt of.Biology Palm Beach Atlantic University West Palm Beach Florida USA

Chem.cally engineered agricultural products such as pesticides, insecticides, and herbicides, although used considerably f.r both industrialized and personal agricultural use, have recently been associated with a num.er of.serious hum.n health disorders. This rapid literature review aim. to accum.late and analyze research f.om.the last ten years, f.cusing specif.cally on the ef.ects of.exposure to glyphosate-based herbicide products such as Roundup as associated with the f.rm.tion of.various neurological disorders. Specif.cally, this review f.cuses on laboratory research using anim.l m.dels or hum.n cell cultures as well as hum.n population-based epidem.ological studies. It associates exposure to glyphosate or glyphosate-based products with the f.rm.tion or exacerbation of.neurological disorders such as Parkinson’s disease, Alzheim.r’s disease, seizures, and autism.spectrum.disorder. In addition, it exam.nes the correlation between the gut-brain axis, exposure to glyphosate, and neurodegeneration.

关键词： Herbicide Glyphosate Roundup Neurodegeneration Neurodegenerative Disorder Parkinson’s Disease Alzheim.r’s Disease Seizures Autism.Spectrum.Disorder Gut-Brain Axis