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Understanding the Recovery of.the Intervertebral Disc:A Comprehensive Review of.In Vivo and In Vitro Studies

Journal of.Bionic Engineering 2024年第4期21卷 1919-1948页

作者： f.ten f.ki f.hmi zaïri Abderrahman Tamoud Melissa Moulart Rym Taktak Nader Haddar f.hed zaïri Sf.x University ENISMaterials Engineering and Environment Laboratory3038SfaxTunisia University of.Lille IMT Nord EuropeJUNIAUniversity of ArtoisULR 4515-LGCgELaboratoire de Génie Civil et geo-Environnement59000LilleFrance PrediTwins Lab 59000LilleFrance Japet Medical Device 59000LilleFrance Sf.x University ENISLaboratory of Advanced Materials3038SfaxTunisia Ramsay Générale de Santé Hôpital PrivéLe Bois59000LilleFrance

Within the consistent daily rhythm of.human lif.,intervertebral discs endure a variety of.complex loads beyond the inf.uences of.gravity and muscle f.rces,leading to signif.cant morphological changes(in terms of.volume,area,and height)as well as biomechanical alterations,including an increase in disc stif.ness and a decrease in intradiscal ***,the discs demonstrate an ability to regain their original morphological and biomechanical characteristics af.er a period of.nocturnal *** preservation of.normal disc f.nction is critically dependent on this recovery phase,which serves to f.restall premature disc *** phenomenon of.disc recovery has been extensively documented through numerous in vivo studies employing advanced clinical techniques such as Magnetic Resonance Imaging(MRI),stadiometry,and intradiscal pressure ***,the f.ndings f.om in vitro studies present a more complex picture,with reports varying between f.ll recovery and only partial recuperation of.the disc ***,research f.cusing on degenerated discs in vitro has shed light on the quantif.able impact of.degeneration on the disc ability to *** dynamics within the disc are considered a primary f.ctor in recovery,yet the disc intricate multiscale structure and its viscoelastic properties also play key *** elements interact in complex ways to inf.uence the recovery mechanism,particularly in relation to the overall health of.the *** objective of.this review is to collate,analyze,and critically evaluate the existing body of.in vivo and in vitro research on this topic,providing a comprehensive understanding of.disc recovery *** understanding of.ers a blueprint f.r f.ture advancements in medical treatments and bionic engineering solutions designed to mimic,support,and enhance the natural recovery processes of.intervertebral discs.

关键词： Intervertebral disc Recovery In vivo vs.in vitro studies Degeneration Viscoelastic ef.ects f.uid dynamics

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Role of.N-f.rmyl peptide receptor 2 in germinal matrix hemorrhage:an intrinsic review of.a hematoma resolving pathway

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Neural Regeneration Research 2024年第2期19卷 350-354页

作者： Jerry flores Jiping Tang Department of.Physiology&Pharmacology Loma Linda University School of MedicineLoma LindaCAUSA

Germinal matrix hemorrhage is one of.the leading causes of.morbidity,mortality,and acquired inf.ntile hydrocephalus in preterm inf.nts in the United States,with little progress made in its clinical *** clots have been shown to elicit secondary brain injury af.er germinal matrix hemorrhage,by disrupting normal cerebrospinal f.uid circulation and absorption af.er germinal matrix hemorrhage causing post-hemorrhagic hydrocephalus *** evidence suggests that rapid hematoma resolution is necessary to improve neurological outcomes af.er hemorrhagic *** articles have demonstrated the benef.cial ef.ects of.stimulating the polarization of.microglia cells into the M2 phenotype,as it has been suggested that they play an essential role in the rapid phagocytosis of.the blood clot af.er hemorrhagic models of.stroke.N-f.rmyl peptide receptor 2(f.R2),a G-protein-coupled receptor,has been shown to be neuroprotective af.er ***2 activation has been associated with the upregulation of.phagocytic macrophage clearance,yet its mechanism has not been f.lly *** literature suggests that f.R2 may play a role in the stimulation of.scavenger receptor *** receptor CD36 plays a vital role in microglia phagocytic blood clot clearance af.er germinal matrix ***2 has been shown to phosphorylate extracellular-signal-regulated kinase 1/2(ERK1/2),which then promotes the transcription of.the dual-specif.city protein phosphatase 1(DUSP1)*** this review,we present an intrinsic outline of.the main components involved in f.R2 stimulation and hematoma resolution af.er germinal matrix hemorrhage.

关键词： AnxA1 f.R2 GMH hematoma resolution hemorrhagic stroke M1 M2 microglia polarization microglia phagocytosis

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Capsule endoscopy and panendoscopy:A journey to the f.ture of.gastrointestinal endoscopy

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World Journal of.Gastroenterology 2024年第10期30卷 1270-1279页

作者： Bruno rosa.JoséCotter Department of.Gastroenterology Hospital da Senhora da OliveiraGuimarães 4835-044Portugal Lif. and Health Sciences Research Institute School of MedicineUniversity of MinhoBraga 4710-057Portugal ICVS/3B's PT Government Associate LaboratoryBraga 4710-057Portugal

In 2000,the small bowel capsule revolutionized the management of.patients with small bowel ***,the technological development achieved by the new models of.double-headed endoscopic capsules,as miniaturized devices to evaluate the small bowel and colon[pan-intestinal capsule endoscopy(PCE)],makes this non-invasive procedure a disruptive concept f.r the management of.patients with digestive *** technology is expected to identif. which patients will require conventional invasive endoscopic procedures(colonoscopy or balloon-assisted enteroscopy),based on the lesions detected by the capsule,i.e.,those with an indication f.r biopsies or endoscopic *** use of.PCE in patients with inf.ammatory bowel diseases,namely Crohn’s disease,as well as in patients with iron def.ciency anaemia and/or overt gastrointestinal(GI)bleeding,af.er a non-diagnostic upper endoscopy(esophagogastroduodenoscopy),enables an ef.ective,saf. and comf.rtable way to identif. patients with relevant lesions,who should undergo subsequent invasive endoscopic *** recent development of.magnetically controlled capsule endoscopy to evaluate the upper GI tract,is a f.rther step towards the possibility of.an entirely non-invasive assessment of.all the segments of.the digestive tract,f.om mouth-to-anus,meeting the expectations of.the early developers of.capsule endoscopy.

关键词： Non-invasive endoscopy Panendoscopy Magnetically controlled capsule endoscopy Crohn’s disease Digestive bleeding

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On the Use of.Monotonicity-Preserving Interpolatory Techniques in Multilevel Schemes f.r Balance Laws

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Communications on Applied Mathematics and Computation 2024年第2期6卷 1319-1341页

作者： Antonio Baeza rosa.Donat Anna Martinez-Gavara Department de Matematiques Universitat de ValenciaDr.Moliner5046100 BurjassotValenciaSpain Department d'Estadistica i Investigacio Operativa Universitat de ValenciaDr.Moliner5046100BurjassotValenciaSpain

Cost-ef.ective multilevel techniques f.r homogeneous hyperbolic conservation laws are very successf.l in reducing the computational cost associated to high resolution shock capturing numerical *** they do not involve any special data structure,and do not induce savings in memory requirements,they are easily implemented on existing codes and are recommended f.r 1D and 2D simulations when intensive testing is *** multilevel technique can also be applied to balance laws,but in this case,numerical errors may be induced by the *** present a series of.numerical tests that point out that the use of.monotonicity-preserving interpolatory techniques eliminates the numerical errors observed when using the usual 4-point centered Lagrange interpolation,and leads to a more robust multilevel code f.r balance laws,while maintaining the ef.iciency rates observed f.rhyperbolic conservation laws.

关键词： Hyperbolic balance laws Well-balanced schemes Multilevel schemes Harten's multiresolution

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Rheological and stability analysis of.cement pastes incorporating silica-based wastes

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Particuology 2024年第6期89卷 144-152页

作者： Julia da rosa.Martins Janaíde Cavalcante Rocha Dachamir Hotza Luciano Senf. Graduate Program in Materials Science and Engineering(PPGMAT) Federal University of Santa Catarina(UFSC)Florianópolis88040-900SCBrazil Graduate Program in Civil Engineering(PPGEC) Federal University of Santa Catarina(UFSC)Florianópolis88040-900SCBrazil Graduate Program in Chemical Engineering(POSENQ) Federal University of Santa Catarina(UFSC)Florianópolis88040-900SCBrazil Department of.Mobility Engineering Federal University of Santa Catarina(UFSC)Joinville89219-600SCBrazil

This study investigates the inf.uence of.waste characteristics,especially zeta potential,on the properties of.cement pastes and *** f.cus is to evaluate the impact of.the zeta potential of.cement particles and waste materials on the sedimentation speed,rheology,and hardening time of.stabilized cement *** Cement II f.40,retarder additive,silica,and f.y ash were used in the *** pastes were prepared,and during the stabilization period,their rheological properties and pH were *** zeta potential and sedimentation speed of.the cement and waste particles were measured at the pH that the pastes presented during the entire stabilization *** the stabilization period,the pastes were subjected to the hardening time *** zeta potential analyses revealed diverse values f.r the dif.erent powder types,with the cement particles exhibiting a zeta potential of.3.0 mV,the silica particles exhibiting−10.5 mV,and the f.y ash particles exhibiting−20.3 *** inf.uence of.the high zeta potential modulus was observed on the sedimentation speed,with the solution containing f.y ash exhibiting a speed of.40.01μm/s,whereas the solution containing only cement exhibited a speed of.99.38μm/*** the pastes,the results indicate that the presence of.f.y ash particles with a signif.cantly negative zeta potential led to a 16%reduction in hardening time compared to particles with a lower modulus of.zeta *** tests showed that the inclusion of.f.y ash particles prevented the f.rmation of.*** the zeta potential inf.uenced agglomerate f.rmation and hardening time,it was f.und to have no ef.ect on yield stress or viscosity.

关键词： Wastes Zeta potential Setting time Rheometry

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A High-Order Localized Artif.cial Dif.usivity Scheme f.r Discontinuity Capturing on 1D Drif.-f.ux Models f.r Gas-Liquid f.ows

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Advances in Applied Mathematics and Mechanics 2024年第1期16卷 47-74页

作者： Adyllyson H.Nascimento Eugenio S.rosa Department of.Energy School of Mechanical EngineeringUniversity of CampinasCampinasBrazil

A computational code is developed f.r the numerical solution of.onedimensional transient gas-liquid f.ows using drif.-f.ux models,in isothermal and also with phase change *** these two-phase models,classical upwind schemes such as Roe-and Godunov-type schemes are generally dif.icult to derive and expensive to use,since there are no treatable analytic expressions f.r the Jacobian matrix,eigenvalues and eigenvectors of.the system of.*** the other hand,the highorder compact f.nite dif.erence scheme becomes an attractive alternative on these occasions,as it does not make use of.any wave propagation inf.rmation f.om the system of.*** present paper extends the localized artif.cial dif.usivity method f.r high-order compact f.nite dif.erence schemes to solve two-phase f.ows with *** numerical method has simple f.rmulation,straightf.rward implementation,low computational cost and,most importantly,*** numerical methodology proposed is validated by solving several numerical examples given in the *** simulations are sixth-order accurate and it is shown that the proposed numerical method provides accurate approximations of.shock waves and contact *** is an essential property f.r simulations of.realistic mass transport problems relevant to operations in the petroleum industry。

关键词： Compressible two-phase f.ows drif.-f.ux model localized artif.cial dif.usivity highorder numerical methods

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Lower Continental Crusts Involved in the Alpine Orogeny:New Insight f.om the Santa Lucia Nappe Metasediments(Corsica,f.ance)

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Acta Geologica Sinica(English Edition) 2024年第4期98卷 904-920页

作者： Chiara f.ASSI Maria DI rosa.Luca PANDOLf. Michele MARRONI Dipartimento di Scienze della Terra Universitàdi PisaVia Santa Maria 5356126 PisaItaly Istituto di Geoscienze e Georisorse IGG-CNRVia Moruzzi50124 PisaItaly

In the Alpine Corsica(f.ance),the Santa Lucia Nappe represents a peculiar unit preserving the unique relicts of.Paleozoic lower to medium continental *** consists of.composite basement af.ected by Permian granulite f.cies metamorphic conditions unconf.rmably covered by a Late Cretaceous clastic sequence(Tomboni Conglomerate and Tralonca f.ysch)af.ected by polyphase def.rmation and *** this work,we present a new reconstruction of.the def.rmation events registered by the Tralonca f.ysch during the Alpine *** D1 phase was testif.ed by rare isoclinal *** D2 phase produced a continuous f.liation and a map-scale sheath-f.ld with a top-to-W sense of.*** D3 phase produced E-verging non-cylindrical f.lds and S3 crenulation cleavage that is not associated to metamorphic *** present the f.rst temperature-pressure-def.rmation(P-T-d)path f.r the Tralonca f.ysch,demonstrating that the Santa Lucia Nappe underwent accretion and then f.rst stage exhumation in the Alpine wedge during the D1 phase with pressure and temperature peaks both occurred under blueschist metamorphic *** D2 phase occurred at lower pressure-temperature conditions during a second stage *** pressure-temperaturedef.rmation path is comparable with those of.the Lower Units(i.e.,the subducted continental units of.Alpine Corsica)suggesting a common geodynamic history.

关键词： blueschist-f.cies metamorphism P-T-d path Santa Lucia Nappe Corsica Alpine orogeny

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The Ti-TAN plasmid toolbox f.r TurboID-based proximity labeling assays in Nicotiana benthamiana

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Journal of.Integrative Plant Biology 2024年第2期66卷 166-168页

作者： Huang Tan Yu Zhou Erik Dinius rosa.Lozano-Durán Department of.Plant Biochemistry Center for Plant MolecularBiology(ZMBP)Eberhard Karls UniversityTubingenD‐72076Germany

Protein-protein interactions and the f.rmation of.protein complexes play a central role in the regulation of.virtually all aspects of.*** identif.cation and characterization of.interactions between proteins is the bas... 详细信息

关键词： proximity complexes enable

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Remediation of.amide pesticide-polluted soils by combined solarization and ozonation treatment

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Pedosphere 2024年第3期34卷 641-651页

作者： Isabel GARRIDO Carmen MMARTINEZ Pilar flores Pilar HELLIN f.lgencio CONTRERAS Jose f.NOLL Department of.Sustainability and Quality Group of.f.uit and Vegetable Products Instituto Murciano de Investigacion y Desarrollo Agrario y MedioambientalLa Alberca 30150(Spain)

Agriculture has a close relationship with nature,but it can also be the source of.negative and permanent environmental *** use of.pesticides in modern agriculture is a common practice,but their side ef.ects on the environment cannot be *** this study,we evaluated a combination of.solarization and ozonation techniques f.r the elimination of.six amide pesticides(boscalid,chlorantraniliprole,cyf.uf.namid,f.uopyram,napropamide,and propyzamide)in *** experiments were perf.rmed with f.ur dif.erent soils to assess the ef.iciency of.this methodology at dif.erent soil temperatures and ozone dosages under laboratory conditions,and then a greenhouse pot experiment was conducted under controlled conditions during *** days af.er the onset of.the experiments,higher degradation percentages of.amide pesticides were observed in ozonized soils than in other treated soils,particularly when ozone was applied at 10 cm soil *** results show that the utilization of.ozonation,along with solarization,represents a valid method f.r degrading residues of.the studied pesticides and suggest that this combined technology may be a promising tool f.r remediating pesticide-polluted soils.

关键词： intermediate ozone pesticide degradation pesticide residue polyethylene f.lm remediation technique

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Optimal combination of.the correction model and parameters f.r the precision geometric correction of.uaV hyperspectral images

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International Journal of.Agricultural and Biological Engineering 2024年第3期17卷 173-184页

作者： Wenzhong Tian za Kan Qingzhan Zhao Ping Jiang Xuewen Wang Hanqing Liu College of.Mechanical and Electrical Engineering Shihezi UniversityShihezi 832000XinjiangChina Research Center f.r Space Inf.rmation Engineering Technology Shihezi 832000XinjiangChina XPCC Division of.National Remote Sensing Center of.China Shihezi 832000XinjiangChina College of.Inf.rmation Science and Technology Shihezi UniversityShihezi 832000XinjiangChina

Nowadays,with the rapid development of.quantitative remote sensing represented by high-resolution uaV hyperspectral remote sensing observation technology,people have put f.rward higher requirements f.r the rapid preprocessing and geometric correction accuracy of.hyperspectral *** optimal geometric correction model and parameter combination of.uaV hyperspectral images need to be determined to reduce unnecessary waste of.time in the preprocessing and provide high-precision data support f.r the application of.uaV hyperspectral *** this study,the geometric correction accuracy under various geometric correction models(including af.ine transf.rmation model,local triangulation model,polynomial model,direct linear transf.rmation model,and rational f.nction model)and resampling methods(including nearest neighbor resampling method,bilinear interpolation resampling method,and cubic convolution resampling method)were ***,the distribution,number,and accuracy of.control points were analyzed based on the control variable method,and precise ground control points(GCPs)were *** results showed that the average geometric positioning error of.uaV hyperspectral images(at 80 m altitude AGL)without geometric correction was as high as 3.4041 m(about 65 pixels).The optimal geometric correction model and parameter combination of.the uaV hyperspectral image(at 80 m altitude AGL)used a local triangulation model,adopted a bilinear interpolation resampling method,and selected 12 edgemiddle distributed *** correction accuracy could reach 0.0493 m(less than one pixel).This study provides a ref.rence f.r the geometric correction of.uaV hyperspectral images.

关键词： geometric correction hyperspectral images unmanned aerial vehicle(uaV) ground control point(GCP)

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