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World Journal of.Gastrointestinal Oncology 2020年第11期12卷 1288-1295页

作者： Anne Katrin Berger Michael Allgäuer Leonidas Apostolidis Anna Elisa Schulze-Schleithof. Uta Merle Dirk Jaeger Georg Martin Haag Department of.Medical Oncology National Center for Tumor DiseasesUniversity Hospital of HeidelbergHeidelberg 69120Germany Department of.Pathology Institute of PathologyUniversity Hospital of HeidelbergHeidelberg 69120Germany Department of.Gastroenterology University Hospital of HeidelbergHeidelberg 69120Germany Department of.Gastroenterology and Hepatology University Hospital of HeidelbergHeidelberg 69120Germany

BACKGROUND Microangiopathic hemolytic anemia(MAHA) with thrombocytopenia and organ f.ilure caused by tumor-associated thrombotic microangiopathy(TMA) is a lif.threatening oncological emergency. Rapid diagnosis and precise distinction f.om other f.rms of.TMA is crucial f.r appropriate therapy, which aims at treating the underlying malignancy. However, the prognosis of.patients with cancer-related(CR)-MAHA is limited. To date, less than 50 patients with gastric cancer and CRMAHA have been reported, mainly as single case reports, and detailed inf.rmation on treatment strategies and outcome are scarce. We analyzed the characteristics and outcomes data of.CR-MAHA patients with gastric cancer treated at our center between 2012 and *** To gain knowledge about CR-MAHA and the course of.*** We retrospectively analyzed patients using an institutional prospectively maintained database. Patients who had CR-MAHA but other cancer types or cancer of.unknown primary were excluded. The basic requirements f.r inclusion were: Histologically proven gastric adenocarcinoma;and clinical diagnosis of.hemolytic anemia with schistocytes with or without thrombocytopenia. The observation period f.r each patient started with the f.rst day of.documented symptoms. The f.llow-up period f.r this analysis ended on f.bruary 1, *** We identif.ed eight patients with a median age of.54 years. Histologically, all patients had(partial) dif.use subtypes of.gastric adenocarcinoma with partial or complete signet cell morphology. All patients had metastatic disease and one patient had a microsatellite instability-high(MSI-H) tumor. In three patients, clinical signs of.MAHA preceded the diagnosis of.cancer, and in two patients, CRMAHA indicated recurrent disease. All patients had severe hemolytic anemia and thrombocytopenia. Six patients experienced severe bone pain, and f.ve patients had dyspnea. Systemic, 5-f.uorouracil-based combination chemotherapy was initiated in six patients, w

关键词： Microangiopathic hemolytic anemia Gastric cancer Chemotherapy Secondline chemotherapy Thrombocytopenia Microsatellite instability-high tumor

Modulation of.lysophosphatidic acid (LPA) receptor activity: the key to successf.l neural regeneration?

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Neural Regeneration Research 2020年第1期15卷 53-54页

作者： Isabel Gross Anja U.Brauer Research Group Anatomy School for Medicine and Health ScienceCarl von Ossietzky University OldenburgOldenburgGermany Research Center f.r Neurosensory Science Carl von Ossietzky University OldenburgOldenburgGermany

The central nervous system(CNS)is characterized by a remarkably elaborate cellular architecture comprising large numbers of.glial and neuronal cells with enormous f.nctional diversity,organized into highly complex and specif.c *** development,the various neural cell types must f.rst be correctly specif.ed,then assume their appropriate positions through caref.lly choreographed cellular migration,and f.nally establish and ref.ne their f.nctional connections,of.en over long *** end result of.all these processes is an extraordinarily intricate anatomical structure,able to receive,integrate,and store inf.rmation and orchestrate appropriate responses.

关键词： neural specif.ed f.nally

COREX（R）设备在印度Jindal Vijayanagar钢公司的成功运行

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中国冶金 2001年第5期 38-43页

作者： D.N.Ghorai,f.J.Bruer,H.f.eydorf.r,D.Siuka Jindal Vijayanagar钢铁有限公司奥钢联工程技术公司奥钢联工程技术公司奥钢联工程技术公司

1 前言 JVSL是印度一家新的钢铁联合企业,位于印度南部Karnataka邦的Toransgallu,这里是Bellary-Hos-pet铁矿区的核心地带。截至2000年12月,新建的钢厂已经能够年产80万t热轧带卷。按计划到2001年二季度最终完成建设后,新厂的热轧带卷... 详细信息

1 前言 JVSL是印度一家新的钢铁联合企业,位于印度南部Karnataka邦的Toransgallu,这里是Bellary-Hos-pet铁矿区的核心地带。截至2000年12月,新建的钢厂已经能够年产80万t热轧带卷。按计划到2001年二季度最终完成建设后,新厂的热轧带卷产能将达

关键词：熔融气化炉 Jindal Vijayanagar 还原竖炉印度南亚粉矿矿石含铁原料 COREX

用于ACS1000标准交流传动装置的仿真工具

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大功率变流技术 1999年第2期 27-32页

作者： G.Bruer 李云浩德

ABB在开发用于中电压等级的新型ACS1000标准交流传动装置的过程中,计算机仿真起着十分重要的作用。不仅其任务的复杂性和产品的多样性要求采用一种强有力的仿真工具,而且为达到费用和时间的设定目标也同样要求如此。Saber仿真机完全可... 详细信息

ABB在开发用于中电压等级的新型ACS1000标准交流传动装置的过程中,计算机仿真起着十分重要的作用。不仅其任务的复杂性和产品的多样性要求采用一种强有力的仿真工具,而且为达到费用和时间的设定目标也同样要求如此。Saber仿真机完全可以满足所有要求,并能提供使模型与实际装置相符所需的验证。由于已把仿真与实验室的试验结合起来,该设计更加完善,可靠性也明显提高,因此便可以在广阔的应用范围内实现优化选择。

关键词：交流传动装置 Saber仿真机应用产品优化

除非你放弃，否则就不会被打垮——洛克非勒写给儿子的信

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中学生阅读与作文 2011年第7期 4-6页

作者：约翰·D·洛克菲勒（TohnD．Rockef. uer）

在我真实的记忆中，没有谁能比林肯更伟大。他编织了一段合众国成功而又令人动容的历史，他用不屈不挠的精神与勇气以及宽厚仁爱之心，使四百万最卑下的黑奴获得解放，同时击碎了二千七百万另一肤色的合众国公民灵魂上的枷锁，结束了因... 详细信息

在我真实的记忆中，没有谁能比林肯更伟大。他编织了一段合众国成功而又令人动容的历史，他用不屈不挠的精神与勇气以及宽厚仁爱之心，使四百万最卑下的黑奴获得解放，同时击碎了二千七百万另一肤色的合众国公民灵魂上的枷锁，结束了因种族仇恨而使灵魂堕落、扭曲和狭隘的罪恶历史。他避免了国家被毁灭的灾难。

关键词：放弃儿子洛克历史灵魂记忆仁爱宽厚

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对芒果和漆酚交叉反应的研究

世界核心医学期刊文摘（皮肤病学分册） 2005年第5期1卷 25-26页

作者： Oka K. Saito f. Yasuhara T. Sugimoto A. 崔荣 Department of.Dermatology Ni ttsu Tokyo Hospital 4-45-16 Ohtsuka Bunkyo-ku Tokyo 1120012 Japan

The allergens causing mango dermatitis have long been suspected to be alk(en)y l catechols and/or alk(en)yl resorcinols on the basis of.observed cross-sensiti vity reactions to mango in patients known to be sensitive to poison ivy and oak (Toxicodendron spp.). Earlier, we reported the 3 resorcinol derivatives:heptade cadienylresorcinol (I), heptadecenylresorcinol (II) and pentadecylresorcinol (II I); collectively named ‘mangol’, as mango allergens. In this study, we extract ed the 1st 2 components (I and II) f.om the Philippine mango, adjusted them to 0 .05%concentration in petrolatum and patch tested the components on 2 subjects w ith mango dermatitis. Both subjects reacted to I. 1 subject also elicited a weak er positive reaction to II. To investigate the cross-reaction between mangol an d urushiol, we also patch tested the same subjects with urushiol. The subject sensitive to II reacted to urushiol. 6 subjects with a history of.lacq uer contact dermatitis and positive reactions to urushiol were similarly patch t ested. 5 persons reacted to I. 2 subjects also exhibited a slower but positive r eaction to II. This is the 1st report in which heptadec(adi)enyl resorcinols kno wn to bepresent in man go have been shown to elicit positive patch test reaction s in mango-sensitive patients.

关键词：交叉反应漆酚间苯二酚毒常春藤阳性反应漆性皮炎过敏患者橡木儿茶酚

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中西药结合治疗马腺疫临床案例分析

中国动物传染病学报 2018年第4期26卷 58-61页

作者：买占海卢亚宾沙娅.奴尔兰齐文静王德超崔耀成于维浩况玲新疆农业大学乌鲁木齐830052 昭苏县西域马业有限公司伊犁马研究繁育中心昭苏835600

本文对新疆伊犁昭苏县某马场的2例马腺疫进行病案分析,采用临床检查和实验室诊断技术对其进行确诊,应用中药透脓散和西药抗生素相结合方式治疗患马,治疗效果显著。本研究结果为今后马腺疫临床诊断和防治提供依据。

关键词：马腺疫诊断防制临床病案

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蔗渣湿法蒸汽爆破法高得率浆的研究和探索

蔗渣湿法蒸汽爆破法高得率浆的研究和探索