检索结果-南通市图书馆

Co-occurrence of.Cell Lines, Basal Media and Supplementation in the Biomedical Research Literature

Journal of.Data and Inf.rmation Science 2020年第3期5卷 161-177页

作者： Jessica Cox Darin McBeath Corey Harper ron Daniel Elsevier Labs 230 Park AvenueNew YorkNY 10169USA

Purpose: The use of.in vitro cell culture and experimentation is a cornerstone of.biomedical research, however, more attention has recently been given to the potential consequences of.using such artif.cial basal medias and undef.ned supplements. As a f.rst step towards better understanding and measuring the impact these systems have on experimental results, we use text mining to capture typical research practices and trends around cell ***/methodology/approach: To measure the scale of.in vitro cell culture use, we have analyzed a corpus of.94,695 research articles that appear in biomedical research journals published in ScienceDirect f.om 2000–2018. Central to our investigation is the observation that studies using cell culture describe conditions using the typical sentence structure of.cell line, basal media, and supplemented compounds. Here we tag our corpus with a curated list of.basal medias and the Cellosaurus ontology using the Aho-Corasick algorithm. We also processed the corpus with Stanf.rd CoreNLP to f.nd nouns that f.llow the basal media, in an attempt to identif. supplements used. f.ndings: Interestingly, we f.nd that researchers f.equently use DMEM even if.a cell line's vendor recommends less concentrated media. We see long-tailed distributions f.r the usage of.media and cell lines, with DMEM and RPMI dominating the media, and HEK293, HEK293 T, and HeLa dominating cell lines used. Research limitations: Our analysis was restricted to documents in ScienceDirect, and our text mining method achieved high recall but low precision and mandated manual inspection of.many *** implications: Our f.ndings document current cell culture practices in the biomedical research community, which can be used as a resource f.r f.ture experimental ***/value: No other work has taken a text mining approach to surveying cell culture practices in biomedical research.

关键词： Cell culture Biomedical research Text mining

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The 5-HT2c receptor gene Cys23Ser polymorphism inf.uences the intravaginal ejaculation latency time in Dutch Caucasian men with lif.long premature ejaculation

引用

Asian Journal of.Andrology 2014年第4期16卷 607-610页

作者： Paddy KC Janssen ron van Schaik Berend Olivier Marcel D Waldinger Division of.Pharmacology Utrecht Institute for Pharmaceutical Sciences Utrecht University Utrecht The Netherlands Department of.Central Hospital Pharmacy Viecuri Hospital Venlo The Netherlands Department of.Clinical Chemistry (AKC) Erasmus University Medical Center (Erasmus MC) Rotterdam The Netherlands Department of.Psychiatry Yale University School of Medicine New Haven Connecticut USA Outpatient Department of.Neurosexology HagaZiekenhuis The Hague The Netherlands.

It has been postulated that the persistent short intravaginal ejaculation latency time （IELT） of.men with lif.long premature ejaculation （LPE） is related to 5-hydroxytryptamine （HT）2c receptor f.nctioning. The aim of.this study was to investigate the relationship of.Cys23Ser 5-HT2c receptor gene polymorphism and the duration of.IELT in men with LPE. Theref.re, a prospective study was conducted in 64 Dutch Caucasian men with LPE. Baseline IELT during coitus was assessed by stopwatch over a 1-month period. All men were genotyped f.r Cys23Ser 5-HT2c receptor gene polymorphism. Allele f.equencies and genotypes of.Cys and Ser variants of.5-HT2c receptor gene polymorphism were determined. Association between Cys/Cys and Ser/Ser genotypes and the natural logarithm of.the IELT in men with LPE ***. As a result, the geometric mean, median and natural mean IELT were 25.2, 27.0, 33.9s, respectively. Of.all men, 20.0%, 10.8%, 23.1% and 41.5% ejaculated within 10, 10-20, 20-30 and 30-60s af.er vaginal penetration. Of.the 64 men, the Cys/Cys and Ser/Ser genotype f.equency f.r the Cys23Ser polymorphism of.the 5-HT2c receptor gene was 81% and 19%, respectively. The geometric mean IELT of.the wildtypes （Cys/Cys） is signif.cantly lower （22.6s; 95% CI 18.3-27.8s） than in male homozygous mutants （Ser/Ser）（40.4s; 95% CI 20.3-80.4s）（P = 0.03）. It is concluded that Cys23Ser 5-HT2c receptor gene polymorphism is associated with the IELT in men with LPE. Men with Cys/Cys genotype have shorter IELTs than men with Ser/Ser genotypes.

关键词： 5-HT2c receptor gene Cys23Ser polymorphism intravaginal ejaculation latency time lif.long premature ejaculation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Detecting and mapping slums using open data:a case study in Kenya

引用

International Journal of.Digital Earth 2020年第6期13卷 683-707页

作者： ron Mahabir Peggy Agouris Anthony Stef.nidis Arie Croitoru Andrew T.Crooks Department of.Geography and Geoinf.rmation Science George Mason UniversityFairfaxVAUSA Center f.r Geoinf.rmatics and Geospatial Intelligence George Mason UniversityFairfaxVAUSA Center f.r Earth Observing and Space Research College of ScienceGeorge Mason UniversityFairfaxVAUSA Criminal Investigations and Network Analysis Center George Mason UniversityFairfaxVAUSA Department of.Computational and Data Sciences George Mason UniversityFairfaxVAUSA

The worldwide slum population currently stands at over one billion,with substantial growth expected in the coming ***,slums have been mapped using inf.rmation derived mainly f.om either physical indicators using remote sensing data,or socio-economic indicators using census *** data source on its own provides only a partial view of.slums,an issue f.rther compounded by data poverty in less-developed *** overcome such issues,this paper explores the f.sion of.traditional with emerging open data sources and data mining tools to identif. additional indicators that can be used to detect and map the presence of.slums,map their f.otprint,and map their *** this goal,we develop an indicator database f.r slums using open sources of.physical and socio-economic data that can be used to characterize slum *** this database,we then leverage data mining techniques to identif. the most suitable combination of.these indicators f.r mapping *** three cities in Kenya as test cases,results show that the f.sion of.these data can improve the mapping accuracy of.*** results suggest that the proposed approach can provide a viable solution to the emerging challenge of.monitoring the growth of.slums.

关键词： Slums remote sensing socioeconomic urban sustainability data mining Kenya

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Spermine induced reversible collapse of.deoxyribonucleic acid-bridged nanoparticle-based assemblies

引用

Nano Research 2018年第1期11卷 383-396页

作者： Kristian L. Goeken Richard B. M. Schasf.ort Vinod Subramaniam ron Gill MIRA Institute f.r Biomedical Technology and Technical Medicine University of Twente Dfienerlolaan 5 7522 NB Enschede the Netherlands Vrije UniversiteitAmsterdam De Boelelaan 1105 1081 HVAmsterdam the Netherlands Saxion University of.Applied Sciences M. H. Tromplaan 28 7513 A8 Enschede the Netherlands

DNA-linked 2D and 3D nano-assemblies f.nd use in a diverse set of.applications, ranging f.om DNA-origami in drug delivery and medical imaging, to DNA-linked nanoparticle structures f.r use in plasmonics and （bio）sensing. However, once these structures have been f.lly assembled, f.w options are available to modulate structure geometry. Here, we investigated the use of.the polycation spermine to induce DNA collapse in small oligonucleotide-linked （54 bp） gold nanoparticle structures by monitoring shif.s in the localized surf.ce plasmon resonance （LSPR） peak and by comparing the data with f.nite-dif.erence time-domain （f.TD） simulations. Our data shows that low concentrations of.spermine can be applied to induce large changes in DNA conf.rmation, leading to a signif.cant reduction in interparticle distance （f.om - 25 to - 3 nm） and enhanced plasmonic coupling. The DNA collapse is near-instantaneous and reversible, and its application at low and high DNA densities is demonstrated with surf.ce plasmon resonance imaging （SPRi）, showing the potential of.spermine to dynamically modulate distances and geometry in DNA-based nano-assemblies.

关键词： nanoparticles spermine deoxyribonucleic acid localized surf.ce plasmonresonance surf.ce plasmon resonanceimaging

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

胡祖:应用于敦巴顿橡树园连香古树保护的日本本土技术

引用

景观设计学（中英文） 2024年第3期12卷 98-102页

作者：罗恩·亨德森乔纳森·卡瓦列尔美国伊利诺伊理工学院建筑学院景观设计与城市规划系芝加哥60616 美国伊利诺伊理工学院阿尔法伍德植物园芝加哥60616 美国LIRIO景观设计事务所纽波特02840 美国敦巴顿橡树园研究中心园地部华盛顿20007

敦巴顿橡树园中的连香树是北美最古老的连香树之一,在该花园建成之前就已存在。日本园艺大师藤元藏人受园方委托,检查并主导对这株古树的保护工作——“胡祖”(hoozue)是一种日本本土技术,通过对树木枝干进行一系列支撑,以使这株每况愈... 详细信息

敦巴顿橡树园中的连香树是北美最古老的连香树之一,在该花园建成之前就已存在。日本园艺大师藤元藏人受园方委托,检查并主导对这株古树的保护工作——“胡祖”(hoozue)是一种日本本土技术,通过对树木枝干进行一系列支撑,以使这株每况愈下的古老树木重新焕发青春。胡祖的建造和实施过程基于对树木的评估,包括对枝干结构的检查,以及对实施后未来几十年生长情况的预测。绳索、树皮保护裹布、钉子等材料的使用,以及木制胡祖本身的制作和安装都是依照日本本土知识和经验进行的,这些知识和经验也以图文的形式记录了下来。本文记述了这一保护项目的过程,展示了这一日本本土技术的重要意义。

关键词：胡祖枝干支架连香树敦巴顿橡树园本土园艺保护园艺

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

维氏美学(绪论·下)

引用

中国美学 2024年第1期 263-271页

作者： [法]维龙 [日]中江兆民郑子路(译) 不详江西师范大学美术学院东京大学

本文是日本启蒙思想家中江兆民所译《维氏美学》的“绪论”的下半部分。在上一辑刊出的上半部分之中,作者阐述了艺术的根源与本质,认为艺术应以感动人心为旨趣,它的本质是作者被外在的事物触动后,通过对自我情感秘韵的摹写,而进入妙境... 详细信息

本文是日本启蒙思想家中江兆民所译《维氏美学》的“绪论”的下半部分。在上一辑刊出的上半部分之中,作者阐述了艺术的根源与本质,认为艺术应以感动人心为旨趣,它的本质是作者被外在的事物触动后,通过对自我情感秘韵的摹写,而进入妙境。对于艺术创作者最重要的,不是学院派那些烦琐的规则,而是情感的真切。只要驱使自我的情感去创作,自然也就可以怡人耳目;下半部分,作者对强调法则,以承袭前人的精神与意趣为旨归的保守势力进行了驳斥,认为“仿效前人”或“以实物为师,追求肖似”的艺术之道都是不可得的,自由而彻底地表达艺术家自我的胸中所感才是真正的艺术之道。

关键词：维氏美学美学总论日本近代美学

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Comparison of.Low Stress Mechanical Properties of.Light Weight Wool and Wool Blend f.brics using the KES-f.and f.ST Instruments

引用

Journal of.China Textile University(English Edition) 2000年第4期17卷 99-102页

作者：王革辉张渭源 Postle ron Phillips David f.shion Inst. China Textile Univ. Shanghai 200051 China

This study compares the test results of.the f.ST (f.bric Assurance by Simple Testing) with those of.the KES - f.(Kawabata Evaluation Systems f.r f.brics) f.r a range of.nineteen light weight wool and wool blend f.brics in terms of.the low - stress mechanical properties of.bending, shear, and tensile def.rmation. It is f.und that there are very signif.cant correlations between the corresponding parameters f.r extensibility and shear rigidity obtained f.om the test results of.the two systems. The correlation between the values of.bending rigidity obtained f.om the two systems is only moderate. f.rthermore, f.r the f.brics tested in this study, the values of.bending rigidity, shear rigidity, and extensibility measured using the KES - f.instruments are higher than those of.the corresponding parameters measured using the f.ST instruments. The linear regression equation is given f.r each pair of.corresponding parameter.

关键词： low stress mechanical properties the KES - f system the f.ST system light weight wool f.brics

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A stepwise process f.r carbon dioxide sequestration using magnesium silicates

引用

f.0}tiers of.Chemical Science and Engineering 2010年第2期4卷 133-141页

作者： Johan f.GERLUND Experience NDUAGU Inês ROMÃO ron ZEVENHOVEN Åbo Akademi University Thermal and Flow EngineeringBiskopsgatan 8FI-20500Åbo/TurkuFinland visiting f.om University of.Coimbra Department of Chemical EngineeringPólo IIPinhal de Marrocos3030-290 CoimbraPortugal

This work involves the production of.magnesium in the f.rm of.Mg(OH)_(2)f.om serpentinite rock(nickel mine tailing)material f.llowed by conversion into MgCO_(3)using a pressurised f.uidised bed(Pf.)reactor operating at 400℃-600℃and pressures up to 2.85 *** approach is rooted in the thermodynamic f.ct that the reaction between Mg(OH)_(2)and gaseous CO_(2)f.rming MgCO_(3)and water releases signif.cant amounts of.*** main problem is,however,the chemical kinetics;the reaction is slow and has to be accelerated in order to be used in an economically viable process f.r large-scale(~1 Mt/a)CO_(2)*** have constructed a labscale Pf. reactor test-setup f.r optimising the carbonation *** high enough temperatures and conversion levels the reaction should provide the heat f.r the proceeding Mg(OH)_(2)production step,making the overall process energy *** f.r we have been able to achieve a conversion degree of.26%at 500℃and 2.85 MPa af.er 30 min(particle size 125-212μm).In this paper the test f.cility and our latest results and progress on CO_(2)mineral carbonation are ***,the possible integration of.the iron as a f.edstock f.r iron and steel production will be brief.y *** interesting side-ef.ect of.this carbon dioxide capture and storage(CCS)route is that signif.cant amounts of.iron are obtained f.om the serpentinite rock *** is released during the Mg(OH)_(2)production and can be of.great interest to the iron-and steel producing sector,which at the same time is f.nland’s largest CO_(2)producer.

关键词： mineralisation serpentinite mineral carbonation magnesium carbonate f.uidised bed

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Crohn's disease and recurrent appendicitis: A case report

引用

World Journal of.Gastroenterology 2005年第43期11卷 6891-6893页

作者： ron Shaoul Yosi Rimar Aurora Toubi Jorge Mogilner Reuven Polak Michael Jaf.e Department of.Pediatrics Department of.Radiology

The clinical diagnosis of.classic Crohn's disease (CD)of.the small bowel is based on a typical history, tender right lower quadrant f.llness or mass, and characteristic radiographic f.ndings of.the terminal ileum. Appendicitis may as well present with chronic or recurrent symptoms and this presentation may be conf.sed with CD. We herein describe the case of.a young teenage girl with a presumptive diagnosis of.CD, who was ultimately diagnosed as having chronic nongranulomatous appendicitis. The literature on the subject is reviewed.

关键词： Chronic appendicitis Crohn's disease Diagnosis Terminal ileitis Adolescent

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Optical waveguiding along nanometer slits

引用

Advanced Photonics 2023年第4期5卷 7-8页

作者： Yuen-ron Shen University of.Calif.rnia Department of PhysicsBerkeleyCaliforniaUnited States

Optical f.eld conf.nement is a topic of.immense interest in optical sci-ence and *** and conf.ning an optical wave in spatial dimensions not only reduces the size of.its f.otprint,but greatly enhan-ces its f.eld stren... 详细信息

关键词： interaction wave f.eld

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：