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The design and performance of charged particle detector onboard the GECAM mission

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Radiation Detection Technology and Methods 2022年第1期6卷 53-62页

作者： Y.B.Xu X.Q.li X.L.Sun S.Yang H.Wang W.X.Peng X.H.liang K.Gong Y.Q.liu D.Y.Guo X.Y.Zhao C.Y.li Z.H.An J.J.He X.J.liu X.Y.Wen S.L.Xiong fan Zhang D.L.Zhang C.Y.Zhang C.Cai Z.Chang G.Chen C.Chen Y.Y.Du M.Gao R.Gao D.J.Hou Y.G.li G.li L.li X.f.li M.S.li f.J.Lu H.Lu B.Meng f.Shi J.Z.Wang Y.S.Wang H.Z.Wang X.Wen S.Xiao Y.P.Xu J.W.Yang Q.B.Yi S.N.Zhang C.M.Zhang f.Zhang Y.Zhao X.Zhou Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China

Background The Gravitational wave highly energetic Electromagnetic Counterpart All-sky Monitor(GECAM)is dedicated to detecting gravitational wave gamma-ray *** is capable of all-sky monitoring over and discovering gamma-ray bursts and new radiation *** consists of two microsatellites,each equipped with 8 charged particle detectors(CPDs)and 25 gamma-ray detectors(GRDs).Purpose The CPD is used to measure charged particles in the space environment,monitor energy and flow intensity changes,and identify between gamma-ray bursts and space charged particle events in conjunction with *** CPD uses plastic scintillator as the sensitive material for detection,silicon photomultiplier array as the optically readable device,and the inlaid Am-241 radioactive source as the onboard calibration *** In this paper,we will present the working principle,physical design,functional implementation and preliminary performance test results of the *** a result,the energy range of electron,gamma-ray detection efficiency and dead time are tested to be better than the indexes required through the ground calibration experiment.

关键词： GECAM CPD SiPM

Design of a cationic accelerator enabling ultrafast ion diffusion kinetics in aqueous zinc-ion batteries

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Journal of Energy Chemistry 2025年第1期100卷 377-384页

作者： Yawei Xiao Qianqian Gu Haoyu li Mengyao li Yude Wang National Center for International Research on Photoelectric and Energy Materials School of Materials and Energy Yunnan University Key Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources School of Chemistry and Chemical Engineering Hainan University College of Chemical Engineering Fuzhou University Yunnan Key Laboratory of Carbon Neutrality and Green Low-carbon Technologies Yunnan University

Aqueous zinc-ion batteries are highly favored for grid-level energy storage owing to their low cost and high safety,but their practical application is limited by slow ion *** address this,a strategy has been developed to create a cation-accelerating electric field on the surface of the cathode to achieve ultrafast Zn2+diffusion *** employing electrodeposition to coat MoS2on the surface of BaV6O16·3H2O nanowires,the directional built-in electric field generated at the heterointerface acts as a cation accelerator,continuously accelerating Zn2+diffusion into the active *** optimized Zn2+diffusion coefficient in CC@BaV-6O16·3H2O@MoS2(7.5×10～8cm2s-1) surpasses that of most reported V-based ***,MoS2serving as a cathodic armor extends the cycling life of the Zn-CC@BaV6O16·3H2O@MoS2full batteries to over 10000 *** work provides valuable insights into optimizing ion diffusion kinetics for high-performance energy storage devices.

关键词： Zinc alloys

Targeting epigenetic mechanisms in amyloid-β-mediated Alzheimer’s pathophysiology:unveiling therapeutic potential

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Neural Regeneration Research 2025年第1期20卷 54-66页

作者： Jennie Z.li Nagendran Ramalingam Shaomin li Ann Romney Center for Neurologic Diseases Brigham and Women’s Hospital and Harvard Medical SchoolBostonMAUSA

Alzheimer’s disease is a prominent chronic neurodegenerative condition characterized by a gradual decline in memory leading to *** evidence suggests that Alzheimer’s disease is associated with accumulating various amyloid-βoligomers in the brain,influenced by complex genetic and environmental *** memory and cognitive deficits observed during the prodromal and mild cognitive impairment phases of Alzheimer’s disease are believed to primarily result from synaptic *** life,environmental factors can lead to enduring changes in gene expression and the emergence of brain *** changes,known as epigenetic modifications,also play a crucial role in regulating the formation of synapses and their adaptability in response to neuronal *** this context,we highlight recent advances in understanding the roles played by key components of the epigenetic machinery,specifically DNA methylation,histone modification,and microRNAs,in the development of Alzheimer’s disease,synaptic function,and activity-dependent synaptic ***,we explore various strategies,including enriched environments,exposure to non-invasive brain stimulation,and the use of pharmacological agents,aimed at improving synaptic function and enhancing long-term potentiation,a process integral to epigenetic ***,we deliberate on the development of effective epigenetic agents and safe therapeutic approaches for managing Alzheimer’s *** suggest that addressing Alzheimer’s disease may require distinct tailored epigenetic drugs targeting different disease stages or pathways rather than relying on a single drug.

关键词： Alzheimer’s disease DNA methylation enriched environments histone modification microRNAs non-invasive brain stimulation synaptic plasticity

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中国地区现代人起源问题研究进展

中国科学：地球科学 2018年第1期48卷 30-41页

作者：高星彭菲付巧妹李锋中国科学院脊椎动物演化与人类起源重点实验室中国科学院古脊椎动物与古人类研究所北京100044 中国科学院大学北京100049 Department of Early Prehistory and Quaternary Ecology University of Tfibingen Tfibingen 72070 Germany

中国乃至东亚地区现代人起源问题,在国际学术界"近期出自非洲说"和"多地区进化说"两派学说激烈争论的背景下一直存在着"本土连续演化"与"非洲移民替代"两种假说的碰撞,两种观点的主要提出与支持者分别来自古人类学和分子生物学界.随着... 详细信息

中国乃至东亚地区现代人起源问题,在国际学术界"近期出自非洲说"和"多地区进化说"两派学说激烈争论的背景下一直存在着"本土连续演化"与"非洲移民替代"两种假说的碰撞,两种观点的主要提出与支持者分别来自古人类学和分子生物学界.随着新材料发现、新分析进展和更多领域介入此项研究,相关认识得到深化,有关假说得以发展和修正,不同人群间发生过基因交流、现代人都经历过复杂的融合与演化过程渐成学术界共识.中国地区新发现的人类化石所揭示的古人类体质特点及其演化,旧石器时代考古研究成果和古DNA信息的提取与破译,正使该地区现代人群起源与形成过程逐渐清晰起来,但不同假说的交锋仍在持续,分子生物学主流观点认定中国地区最早现代人来自西方,古人类学和考古学则在强化对"连续进化附带杂交"观点的论述.本文梳理、总结了近年中国在此问题上的研究进展及西方学术界的相关发展变化,分析了研究中存在的问题,对未来方向提出了思路与建议.

关键词：中国地区现代人起源现代行为近期出自非洲说连续进化附带杂交学科交叉

基于改进粒子群优化算法的混流装配线演进平衡

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计算机集成制造系统 2017年第4期23卷 781-790页

作者：吴永明戴隆州李少波罗利飞贵州大学现代制造技术教育部重点实验室贵州贵阳550025

随着产品需求的多样化、装配工艺及技术进步、设备更新等动态变化,装配线平衡方案需不断调整,甚至重新规划与演进平衡。为了探究上述因素对混流装配线演进平衡的影响,提出了实现装配线演进平衡的方法,建立了以最小化装配线的生产节拍、... 详细信息

随着产品需求的多样化、装配工艺及技术进步、设备更新等动态变化,装配线平衡方案需不断调整,甚至重新规划与演进平衡。为了探究上述因素对混流装配线演进平衡的影响,提出了实现装配线演进平衡的方法,建立了以最小化装配线的生产节拍、站间平滑指数、演进平衡调整成本为优化目标的混流装配线演进平衡数学模型,并通过改进粒子群优化算法进行优化。在该算法中,为增加粒子的多样性和搜索能力,克服传统粒子群优化算法快速收敛等问题,以粒子进化的成功率来更新算法中的惯性因子,将群体中非最优粒子中的有利信息迁移到群体中的最优粒子上,从而加快算法的搜索速度。结合某企业的生产实例验证了该方法的有效性和可行性。

关键词：混流装配线演进平衡粒子群优化算法优化

Multilevel analysis of the central-peripheral-target organ pathway:contributing to recovery after peripheral nerve injury

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Neural Regeneration Research 2025年第10期20卷 2807-2822页

作者： Xizi Song Ruixin li Xiaolei Chu Qi li Ruihua li Qingwen li Kai-Yu Tong Xiaosong Gu Dong Ming Academy of Medical Engineering and Translational Medicine Tianjin UniversityTianjinChina Haihe Laboratory of Brain-Machine Interface and Human-Machine fusion TianjinChina Department of Rehabilitation Tianjin University Tianjin HospitalTianjinChina Department of Hand Microsurgery Tianjin University Tianjin HospitalTianjinChina School of Exercise and Health Tianjin University of SportTianjinChina Department of Biomedical Engineering the Chinese University of Hong KongHong Kong Special Administrative RegionChina

Peripheral nerve injury is a common neurological condition that often leads to severe functional limitations and *** on the pathogenesis of peripheral nerve injury has focused on pathological changes at individual injury sites,neglecting multilevel pathological analysis of the overall nervous system and target *** has led to restrictions on current therapeutic *** this paper,we first summarize the potential mechanisms of peripheral nerve injury from a holistic perspective,covering the central nervous system,peripheral nervous system,and target *** peripheral nerve injury,the cortical plasticity of the brain is altered due to damage to and regeneration of peripheral nerves;changes such as neuronal apoptosis and axonal demyelination occur in the spinal *** nerve will undergo axonal regeneration,activation of Schwann cells,inflammatory response,and vascular system regeneration at the injury *** damage to target organs can occur,including skeletal muscle atrophy and sensory receptor *** then provide a brief review of the research advances in therapeutic approaches to peripheral nerve *** main current treatments are conducted passively and include physical factor rehabilitation,pharmacological treatments,cell-based therapies,and physical ***,most treatments only partially address the problem and cannot complete the systematic recovery of the entire central nervous system-peripheral nervous system-target organ ***,we should further explore multilevel treatment options that produce effective,long-lasting results,perhaps requiring a combination of passive(traditional)and active(novel)treatment methods to stimulate rehabilitation at the central-peripheral-target organ levels to achieve better functional recovery.

关键词： central nervous system central peripheral target organ multilevel pathological analysis nerve regeneration peripheral nerve injury peripheral nervous system target organs therapeutic approach

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城镇老年文化消费市场探析

消费经济 2005年第2期21卷 62-64页

作者：刘飞燕南京师范大学商学院江苏南京210097

老龄问题越来越成为一个刻不容缓的重要社会问题。但我国老龄产业的发展,特别是老年文化消费市场的开拓,远远不能满足老年的文化需要。大力开拓老年文化消费市场,是保持我国经济和社会协调发展、建设社会主义和谐社会的必然要求,也是弘... 详细信息

老龄问题越来越成为一个刻不容缓的重要社会问题。但我国老龄产业的发展,特别是老年文化消费市场的开拓,远远不能满足老年的文化需要。大力开拓老年文化消费市场,是保持我国经济和社会协调发展、建设社会主义和谐社会的必然要求,也是弘扬中华民族传统美德,形成敬老、养老、助老以及代际和谐的良好社会风尚,推进社会主义精神文明建设的客观要求。

关键词：老年人文化消费市场中国老龄产业文化产品

基于系统保护规划法的长江中下游鱼类保护区网络规划

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中国科学：生命科学 2015年第3期45卷 1244-1257页

作者：黄心一李帆陈家宽复旦大学生物多样性科学研究所上海200438 南昌大学生命科学研究院流域生态学研究所南昌330031

以长江中下游为例,采用系统保护规划法来开展鱼类保护区网络的顶层规划,选择了栖息于长江中下游的153种鱼类,其中,142种鱼类的分布信息来自物种分布建模和后续相关处理,11种鱼类的分布信息来自于人为指定.以这些鱼类的分布信息为基础,采... 详细信息

以长江中下游为例,采用系统保护规划法来开展鱼类保护区网络的顶层规划,选择了栖息于长江中下游的153种鱼类,其中,142种鱼类的分布信息来自物种分布建模和后续相关处理,11种鱼类的分布信息来自于人为指定.以这些鱼类的分布信息为基础,采用Marxan保护规划软件来执行保护规划.为了同时考虑保护区网络的代表性、维持性和高效性,在规划过程中考虑了已建立湿地自然保护区、人类干扰、保护区间的水文连通性等因素,并为各鱼类设定了适当的代表性目标.通过运行Marxan,得到了每个规划单元的选择频率和一个最优解.规划单元选择频率表示一个规划单元的保护重要性,而最优解是一个理想的鱼类保护区网络.结果显示,无论是选择频率高的规划单元还是最优解都仅有少部分位于现有的湿地自然保护区网络内,这说明长江中下游鱼类存在着明显的保护空缺.本研究得到的最优解可以作为构建长江中下游鱼类保护区网络的参考.解中的规划单元在一定程度上可以用其他的规划单元来替代,这一灵活性使得在现实中执行本规划方案时可以灵活避开意外的阻碍.最后,建议在遵循一个淡水管理框架的基础上来执行本规划方案.

关键词：长江中下游鱼类保护系统保护规划保护区网络 Marxan

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Control of Corner Separation for a linear Compressor Cascade via Bionic Slanting Riblets at the Endwall

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Journal of Thermal Science 2025年第1期34卷 129-144页

作者： ZHANG Peng li Yonghong CHENG Rixin Key Laboratory of Civil Aircraft Airworthiness Technology Civil Aviation University of China College of Aeronautical Engineering Civil Aviation University of China

A new passive control approach,utilizing bionic slanting riblets,is employed to mitigate the flow close to the blade endwall in a linear cascade,and its effectiveness and mechanism in controlling corner separation are investigated through numerical *** slanting riblets are positioned at the endwall upstream of the cascade channel,and the influence of riblet height,yaw angle and relative position on the control of corner separation is *** findings indicate that the application of slanting riblets can efficiently counteract corner separation across the stable operational ***,the introduction of riblets with a height of merely 0.1 times the boundary layer thickness results in a significant reduction in total pressure loss by up to 14.53%,while simultaneously enhancing the static pressure coefficient by 21.74%.flow analysis reveals that minute vortices produced within the riblet channels tend to coalesce,forming a potent large-scale vortex near the boundary layer's base *** phenomenon results in reduced additional losses compared to conventional vortex ***,the induced vortex promotes enhanced mixing between the mainstream flow and boundary layer,inhibiting the lateral displacement of low-energy fluids within the endwall boundary ***,this delays the onset of separation vortex formation and eliminates vortex rings in the corner region,ultimately enhancing the aerodynamic efficiency of the cascade.

关键词： additional losses compressor cascade corner separation slanting riblets vortex generator