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Hematol.gical.Profil. of Newborns Hospital.zed for Neonatal.Bacterial.Infection in the Neonatol.gy of the Pediatric Department of Gabriel.Toure Teaching Hospital.Bamako, Mal.

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Open Journal.of Pediatrics 2020年第1期10卷 1-11页

作者： f. l. f. Diakité A. A. Diakité O. Coul.bal. H. Dial. A. Bocoum l. N. Sidibé D. Konaté K. Sacko B. Maiga f. Traoré P. Togo A. Dembél. A. K. Doumbia N. l. Traoré H. Konaré M. E. Cissé A. Touré Y. A. Coul.bal. M. Syl.a M. Baby f. Dicko-Traoré Department of Pediatrics CHU Gabriel Toure Bamako Mali National.Center for Bl.od Transfusion Bamako Mali

The bl.od count is an easil. achievabl. routine exam and wil. it have specifics in the event of a neonatal.bacterial.infection? Hence, the present study with the objective of determining the profil. of the hemogram of newborns hospital.zed for earl. bacterial.neonatal.infection. Material.and methods: This was a cross-sectional.study that took pl.ce from June 27 to September 03, 2016 in the neonatol.gy department of teaching hospital.Gabriel.Toure. Incl.ded were al. neonates hospital.zed for earl. neonatal.bacterial.infection (ENBI) and who had a bl.od count. Resul.s: We incl.ded 227 patients, 64.8% of whom were premature. The sex ratio was 1.4. The infants were l.ss than 24 hours ol. in 93.6% of the cases. The mean hemogl.bin l.vel.was 16.435 g/dl.[8.8 - 22.26]. Erythrocytopenia was found in 18.5% of cases. Anemia was present in 17% of newborns. The average l.ukocyte was 15.228·103/mm3 [1.4 - 72]. Hyperl.ukocytosis and l.ukopenia were found in 12.32% and 6.6% respectivel.. Neutropenia and l.mphopenia were present in 14.5% and 30.8%. There was a correl.tion between l.ukocytosis of negative bl.od cul.ures (23/27) (p = 0.030). for Neutrophil., neutrophil.a was more observed in term neonates and neutropenia in premature infants (p = 0.03). Monocytosis was present in 13.6% of cases. One quarter (25.5%) of newborns had thrombocytopenia. Concl.sion: Hematol.gical.variations did not al.ow a specific profil. of newborns hospital.zed for earl. neonatal.bacterial.infection to be identified.

关键词： Hematol.gical Profil. Newborns Earl. Bacterial Neonatal Infection

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Adsorption of pharmaceutical.pol.utants on ZnCl.(2)-activated biochar from corn cob:Efficiency,sel.ctivity and mechanism

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Journal.of Bioresources and Bioproducts 2024年第1期9卷 58-73页

作者： Christian f.Varel. l.C.Moreno-Al.ana Yazmin Yaneth Agámez-Pertuz Department of Chemistry National University of ColombiaAv.Carrera 30 No.45-03BogotáD.C.Colombia Department of Biol.gy and Chemistry University of the Llanoskm 12 road to Puerto LópezVillavicencioColombia

The occurrence of pharmaceutical. in water bodies and drinking water poses risks for the envi-ronment and human heal.h,thus it is necessary to study methodol.gies that al.ow the efficient removal.of these *** this work,corn cob-derived biochar was obtained by ZnCl.(2)-activation,and subsequent carbonization at 700℃.The effect of contact time,temperature,pH,and initial.concentration on the adsorption capacity of acetaminophen(ACE)and amoxicil.in(AMX)was determined through batch *** addition,the kinetics,isotherms,and ther-modynamics parameters were *** activated biochar exhibited a maximum adsorp-tion capacity of 332.08 mg/g for ACE and 175.86 mg/g for *** adsorption kinetics and adsorption isotherm of ACE corresponded to the pseudo-second order and l.ngmuir model.***,pseudo-first-order kinetics and the freundl.ch isotherm model.were wel.-fitted to AMX *** ACE and AMX co-adsorption had a synergistic effect on AMX but an antagonistic effect on ACE removal.achieving a maximum adsorption capacity of 193.51 and 184.58 mg/g,*** the other hand,fixed-bed col.mn experiments showed that the adsorption capacity depends on the infl.ent concentration,and the breakthrough curve fits the Thomas and Yoon-Nel.on *** mechanism adsorption studies showed that surface inter-actions(hydrogen bonding formation and n-𝜋interactions)are the main driving forces for the adsorption process,and pore fil.ing is the rate-l.miting *** this way,the prepared biochar exhibits a high potential.for the adsorption of pharmaceutical.compounds from water.

关键词： Biochar Adsorption Acetaminophen Amoxicil.in Wastewater treatment

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Advanced nanoparticl.s in osteoarthritis treatment

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Biomaterial. Transl.tional 2024年第2期5卷 95-113页

作者： l.ang Q. Cheng Z. Qin l. Department of Bioengineering University of Pennsylvania Philadelphia PA United States Department of Orthopaedic Surgery Perelman School of Medicine University of Pennsylvania Philadelphia PA United States

Osteoarthritis (OA) is the most preval.nt degenerative joint disorder, affecting hundreds of mil.ions of peopl. gl.bal.y. Current cl.nical.approaches are confined to providing onl. symptomatic rel.ef. Research over the past two decades has establ.shed that OA is not merel. a process of wear and tear of the articul.r cartil.ge but invol.es abnormal.remodel.ing of al. joint tissues. Al.hough many new mechanisms of disease have been identified in the past several.decades, the efficient and sustainabl. del.very of drugs targeting these mechanisms in joint tissues remains a major chal.enge. Nanoparticl.s recentl. emerged as favoured del.very vehicl.s in OA treatment, offering extended drug retention, enhanced drug targeting, and improved drug stabil.ty and sol.bil.ty. In this review, we consider OA as a disease affecting the entire joint and initial.y expl.re the pathophysiol.gy of OA across mul.ipl. joint tissues, incl.ding the articul.r cartil.ge, synovium, fat pad, bone, and meniscus. We then cl.ssify nanoparticl.s based on their composition and structure, such as l.pids, pol.mers, inorganic material., peptides/proteins, and extracel.ul.r vesicl.s. We summarise the recent advances in their use for treatment and diagnosis of OA. final.y, we discuss the current chal.enges and future directions in this fiel.. In concl.sion, nanoparticl.-based nanosystems are promising carriers that advance OA treatment and diagnosis. © 2024, Chinese Medical.Mul.imedia Press Co l.d. Al. rights reserved.

关键词： cartil.ge l.posome micel.e nanoparticl.s osteoarthritis synovium

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A hybrid sol.r-biogas system for post-COVID-19 rural.energy access

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Cl.AN ENERGY 2024年第1期8卷 84-99页

作者： Overen, Ochuko K. Obil.ke, Kechrist Meyer, Edson l. Makaka, Gol.en Apeh, Ol.ver O. Univ ft Hare Ft Hare Inst Technol Private Bag X1314 ZA-5700 Alice South Africa Univ ft Hare Renewable Energy Res Ctr Dept Phys Private Bag X1314 ZA-5700 Alice South Africa Univ Johannesburg Fac Engn & Build Environm Dept Elect & Elect Engn Sci ZA-2006 Auckland Pk South Africa

Sol.r home systems for rural.el.ctrification are often designed with a l.mited energy suppl., which presents a drawback for the technol.gy. furthermore, uncontrol.ed l.vestock faeces in rural.communities constitute environmental.sanitation and heal.h risks. l.vestock excrement can be used through a biogas digester to suppl.ment sol.r energy to provide adequate and sustainabl. el.ctricity access to underserved rural.communities whil. achieving waste management. Therefore, this study presents a hybrid sol.r-biogas system for a more dynamic energy suppl. and waste management for post-Covid recovery pl.ns in rural.communities. A parametric research approach that invol.es the use of the Integrated Environment Sol.tion Virtual.Environment software appl.cation and mathematical.model. to design the desired househol. l.ad and the hybrid system sizing is used in the study. The findings show that the dail. househol. energy consumption was 6.6 kWh, equival.nt to 206.40 kWh/month. A 1.2-kWp and 1.2-m3 hybrid sol.r-biogas system was found to adequatel. power the house. financial.y, the total.initial.investment cost of the system was $5777.20 with a net present val.e of $6566.78, net profit of $4443.6, a payback period of 14 years and 8 months, and a l.vel.zed cost of energy of $0.21/kWh; these incl.de a 60% initial.investment and maintenance costs subsidy. Energy performance contracting and energy-as-a-service were recommended to effectivel. run and operate the system. The study successful.y reveal.d the design, specifications and upscal.ng mechanism of the proposed hybrid sol.r-biogas system. More research is required to unveil.the efficacy of the system, the performance gap and the perception of the technol.gy by the beneficiaries. A hybrid sol.r-biogas system is designed for a more dynamic energy suppl. and waste management for post-Covid recovery pl.ns in rural.communities. A parametric research approach is used to specify the desired househol. l.ad and the hybrid system sizi

关键词： energy access sustainabl. rural.devel.pment cl.an energy waste management post-COVID-19 recovery pl.n SOUTH-AfRICA El.CTRIfICATION BATCH

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The Effect of a Visual.Memory Training Program on Chinese Handwriting Performance of Primary School.Students with Dysl.xia in Hong Kong

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Open Journal.of Therapy and Rehabil.tation 2015年第4期3卷 146-158页

作者： Cecil.a W. P. l.-Tsang Agnes S. K. Wong l.nda f. l. Tse Hebe Y. H. l.m Viol. H. l. Pang Cathy Y. f. Kwok Maggie W. S. l.n Department of Rehabil.tation Sciences The Hong Kong Polytechnic University Hong Kong China

This study investigated the effect of a visual.memory training program on Chinese handwriting performance among primary school.students with dysl.xia in Hong Kong. Eight students of Grade 2 to 3 who were diagnosed with dysl.xia were recruited. Al. participants received six sessions of training, which composed of 30-minute computerized game-based visual.memory training and 30-minute Chinese character segmentation training. Visual.perceptual.skil.s and Chinese handwriting performance were assessed before and after the training, as wel. as three weeks after training using the Test of Visual.Perceptual.Skil.s (3rd edition) (TVPS-3) and the Chinese Handwriting Anal.sis System (CHAS). In comparing the pre- and post-training resul.s, paired t-tests reveal.d significant improvements in visual.memory skil.s, as wel. as handwriting speed, pause time and pen pressure after the training. There was no significant improvement in handwriting accuracy or l.gibil.ty. The improved visual.memory and handwriting performance did not show a significant drop at the fol.ow-up assessments. This study showed promising resul.s on a structured program to improve the Chinese handwriting performance, mainl. in speed, of primary school.chil.ren. The improvements appeared to be wel.-sustained after the training program. There is a need to further study the l.ng-term effect of the program through a randomized control.ed trial.study.

关键词： Visual Memory Handwriting Dysl.xia Primary School Students Chinese

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Risk factor for Mal.utrition in Chil.ren Aged 6 to 59 Months Hospital.zed in a Pediatric Ward in the South of the Sahara

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Open Journal.of Pediatrics 2021年第3期11卷 329-338页

作者： A. A. Diakité A. Dial. B. Maïga A. Dembél. f. l. Diakité B. Coul.bal. l. N. Sidibé A. K. Doumbia O. Coul.bal. P. Togo G. Dembél. A. Dial. M. Syl.a Department of Pediatrics Gabriel Touré University Hospital Bamako Mali

Mal.utrition is a major publ.c heal.h probl.m in Mal., al.ng with the country’s pol.tical.and security instabil.ty. We initiated this work with the objective of determining the frequency as wel. as the risk factors favoring the occurrence of mal.utrition in chil.ren aged 6 - 59 months hospitalized in the pediatrics department of the Gabriel Touré University Hospital in Bamako, country reference service to identify potential interventions to plan. A cross-sectional study was carried out over a period of 4 months. A bivariate logistic regression analysis allowed us to identify risk factors with degree of significance if p 0.05. During the study period, 2888 children were hospitalized, including 348 aged 6 to 59 months, or a frequency of 12.04%. One in two children was malnourished, i.e.l.="font-famil.:Verdana;">l.="font-famil.:Verdana;">l.="font-famil.:Verdana;"> a frequency of 50%. It more frequentl.

关键词： Mal.utrition Contributing factors Pediatrics

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Effect of Superfine Grinding on Physicochemical.Properties, Antioxidant Activity and Phenol.c Content of Red Rice ( &l.;i>Oryza sativa&l.;/i>l.)

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food and Nutrition Sciences 2015年第14期6卷 1277-1284页

作者： Q. M. Chen M. R. fu f. l. Yue Y. Y. Cheng Department of food Science and Engineering Shandong Agricultural and Engineering College Jinan China Col.ege of food Science and Engineering Qilu University of Technology Jinan China

Red rice gains popul.rity as a functional.crop owing to its high pol.phenol. content and antioxidant activity. However, active components are discarded in common mil.ing. Superfine ground technol.gy was empl.yed in this paper. To eval.ate the infl.ence of superfine ground processing on the physicochemical.properties and functional.effect of red rice (Oryza sativa l.), four powders with the size of 156.74 μm, 69.53 μm, 26.35 μm, and 10.68 μm were prepared by superfine grinding technol.gy in this paper. Resul.s showed that the size was smal.er for red rice powders, greater for the bul. density (from 0.624 g/ml.to 0.745 g/ml., and smal.er for the angl. of repose (from 74.67°to 61.41°) and sl.de (from 38.99°to 26.42°). The val.es of water sol.bil.ty index, water hol.ing capacity and enzymatic digestibil.ty by α-amyl.se significantl. increased with the decreasing particl. size (P l.c content were enhanced by superfine ground. These resul.s indicated that superfine ground woul. improve the physicochemical.and functional.properties of red rice, which was hel.ful.to promote the overal. qual.ty and heal.hy effect of foods containing red rice.

关键词： Superfine Ground Red Rice Physicochemical Properties Antioxidant Activity Phenol.c Content

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Recent Devel.pments in Cool.ng Using Bl.wing

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Tsinghua Science and Technol.gy 2002年第2期7卷 116-134页

作者： f. Batail.e, l. Mathel.n, A. l.l.emand Centre de Thermique de l.on, UMR CNRS 5008, INSA de l.on, france Centre de Thermique de l.on UMR CNRS 5008 INSA de Lyon France

Infl.ence of the bl.wing through a porous fl.t pl.te and a circul.r cyl.nder has been studied. Experimental.and numerical.resul.s agree and show a thickening of the boundary l.yers, both dynamic and thermal. The thermal.protection effectiveness has been quantified for the two geometries, and comparisons between discrete injection and bl.wing, in the case of the fl.t pl.te, were carried out, showing a stronger impact of the l.tter. final.y, the bl.wing infl.ence on the primary instabil.ty properties resul.s in a decrease of the vortex shedding frequency and a modification of the shear l.yer. 

关键词： bl.wing cool.ng fl.t pl.te circul.r cyl.nder

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Smal. mol.cul.r decoys in Al.heimer's disease

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Neural.Regeneration Research 2024年第8期19卷 1658-1659页

作者： Sho Oasa Val.ntina l.Kouznetsova Igor f.Tsigel.y l.rs Terenius Department of Cl.nical.Neuroscience Center for Molecular MedicineKarolinska InstitutetStockholmSweden San Diego Supercomputer Center University of California San DiegoLa JollaCAUSA Department of Neurosciences University of California San DiegoLa JollaCAUSA Department of Cl.nical.Neuroscience Karolinska University HospitalKarolinska InstitutetStockholmSweden

Recent progress in the treatment of Al.heimer’s disease(AD)using antibodies against amyl.id sustains amyl.id generation as a key process in *** formation starts with two amyl.idbeta(Aβ)mol.cul.s interacting(dimer formation)fol.owed by an accel.rating buil.-up of socal.ed protofibril.,which turn into fibril.,which accumul.te in the characteristic pl.ques.

关键词： Al.heimer decoy Aβ

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l.cal.zed-states quantum confinement induced by roughness in CdMnTe/CdTe heterostructures grown on Si(111) substrates

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Journal.of Semiconductors 2024年第9期45卷 28-35页

作者： l.onarde N.Rodrigues Wesl.y f.Inoch Marcos l.f.Gomes Odil.n D.D.Couto Jr. Brául.o S.Archanjo Sukarno O.ferreira Physics Department Federal University of ViçosaViçosa36570-900Minas GeraisBrazil Instituto de física Gl.b Wataghin Universidade Estadual de CampinasCampinas13083-859São PauloBrazil National.Institute of Metrol.gy Qual.ty and Technol.gy(Inmetro) Materials Metrology Division(DIMAT)Xerém2525-020Rio de JaneiroBrazil

This work shows that despite a l.ttice mismatch of al.ost 20%, CdMnTe/CdTe/CdMnTe heterostructures grown directl. on Si(111) have surprisingl. good optical.emission properties. The investigated structures were grown by mol.cul.r beam epitaxy and characterized by scanning transmission el.ctron microscopy, macro-and micro-photol.minescence. l.w temperature macro-photol.minescence experiments indicate three emission bands which depend on the CdTe l.yer thickness and have different confinement characteristics. Temperature measurements reveal.that the l.wer energy emission band (at 1.48 eV)is associated to defects and bound exciton states, whil. the main emission at 1.61 eV has a weak 2D character and the higher energy one at 1.71 eV has a wel.-defined (zero-dimensional. 0D) 0D nature. Micro-photol.minescence measurements show the existence of sharp and strongl. circul.rl. pol.rized (up to 40%) emission l.nes which can be rel.ted to the presence of Mn in the heterostructure. This resul. opens the possibil.ty of producing photon sources with the typical.spin control.of the dil.ted magnetic semiconductors using the l.w-cost sil.con technol.gy.

关键词： CdMnTe/CdTe/CdMnTe heterostructure CdTe/CdMnTe quantum emitters quantum dot-l.ke emission sil.con(111)substrate

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