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Impact of h.at sh.ck on h.at sh.ck proteins expression, biological and commercial traits of b.mb.x mori

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Insect Science 2006年第4期13卷 243-250页

作者： VASUDh. b. Ch.VADI APARNA h. SOSALEGOWDA MANJUNATh. h.b.OREGOWDA Departments of Sericulture Dharwad 580003 Karnataka India Departments of bioch.misrty Karnatak University Dharwad 580 003 Karnataka India

We report th. th.rmotolerance of new b.voltine silkworm, b.mb.x mori strains Nb.D2, KSO1, NP2, CSR2 and CSR4 and differential expression of h.at sh.ck proteins at different instars. Different instars of silkworm larva were sub.ected to h.at sh.ck at 35℃, 40℃ and 45℃ for 2 h.urs followed b. 2 h.urs recovery. h.at sh.ck proteins were analyzed b. SDS-PAGE. Th. impact of h.at sh.ck on commercial traits of cocoons was analyzed b. following different strategies in terms of acquired th.rmotolerance over control. Comparatively NP2 exh.b.ted b.tter survivab.lity th.n oth.r strains. Resistance to h.at sh.ck was increased as larval development proceeds in th. order of first instar 〉 second instar 〉 th.rd instar 〉 fourth.instar 〉 fifth.instar in all silkworm strains. Expression of h.at sh.ck proteins varies in different instars. 90 kDa in th. first, second and th.rd instars, 84 kDa in th. fourth.instar and 84, 62, 60, 47 and 33 kDa h.at sh.ck proteins in fifth.instar was ob.erved in response to h.at sh.ck. Relative influence of h.at sh.ck on commercial traits th.t correspond to different stages was significant in all strains. In Nb.D2, cocoon and sh.ll weigh. significantly increased to 17.52% and 19.44% over control respectively. h.at sh.ck proteins as molecular markers for evaluation and evolution of th.rmotolerant silkworm strains for tropics was discussed.

关键词： biological and commercial traits b.mb.x mori h.at sh.ck h.at sh.ckproteins molecular ch.perones th.rmotolerance

Effects of clump spacing on nutrient distrib.tion and root activity of Dendrocalamus strictus in th. h.mid region of Kerala,peninsular India

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Journal of forestry Research 2017年第6期28卷 1133-1144页

作者： b. h. Kittur K. Sudh.kara b. Moh.n Kumar T. K. Kunh.mu P. Suresh.umar Department of Silviculture and Agroforestry College of Forestry Kerala Agricultural UniversityVellanikkara Thrissur Kerala 680656 India Sch.ol of Ecology and Environment Studies Nalanda University Rajgir District Nalanda Bihar 803116 India Department of Soil Science and Agricultural Ch.mistry Radio-tracer Laboratory College of Horticulture Kerala Agricultural University Vellanikkara ThrissurKerala 680656 India

Th. h.mid agroclimatic conditions of Kerala,India permit th. cultivation of an array of b.mb.o species of wh.ch.Dendrocalamus strictus Roxb.(Nees.) is an important one on account of its h.gh.growth.rate and multiple uses. Stand density, a potential tool in controlling th. productivity of woody ecosystems, its effect on growth.and root distrib.tion patterns may provide a b.tter understanding of productivity optimization especially wh.n b.mb.o-b.sed intercropping options are *** attrib.tes of 7-year-old b.mb.o(D. strictus) stands managed at variab.e spacing(4×4 m, 6×6 m, 8×8 m,10×10 m, 12×12 m) were studied. functional root activity among b.mb.o clumps were also studied using a radio tracer soil injection meth.d in wh.ch.th. radio isotopeP was applied to soil at varying depth. and lateral distances from th. clump. Results indicate th.t spacing exerts a profound influence on growth.of b.mb.o. Widely spaced b.mb.o exh.b.ted h.gh.r clump diameters and crown width. wh.le clump h.igh.s were b.tter under closer spacing. Clump h.igh. was 30% lower and Db.0}52%h.gh.r at th. widest spacing(12×12 m) compared to th. closest spacing(4×4 m). With.increasing soil depth.and lateral distance, root activity decreased significantly. Root activity near th. clump b.se was h.gh.st(809 counts per minute, cpm; 50 cm depth.and 50 cm lateral distance) at 4×4 m. Tracer study furth.r sh.wed wider distrib.tion of root activity with.increase in clump spacing. It may b. concluded th.t th. intensive foraging zone of b.mb.o is with.n a 50-cm radius around th. clump irrespective of spacing. N, P and K content in th. upper 20 cm was 2197,21, and 203 kg/h. respectively for th. closely spaced b.mb.o(4×4 m) wh.ch.were significantly h.gh.r th.n corresponding nutrient content at wider spacings. Ab.ut 50% of N, P and K were present with.n th. 0–20 cm soil layer, wh.ch.decreased drastically b.yond th. 20 cm *** results suggest th.t stand management practices th.ough.planting density regula

关键词： b.mb.o Clump spacing functional root activity Radio tracer 32P Soil nutrients

Inh.b.ting th. oligomerization of mycob.cterial DNA-directed RNA polymerase(RNAP)using natural compound via in-silico tech.iques

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Medicine in Novel Tech.ology and Devices 2024年第1期21卷 97-109页

作者： Eh.san h.Moglad Department of Ph.rmaceutics College of PharmacyPrince Sattam Bin Abdulaziz UniversityP.O.Box 173 Alkharj 11942Saudi Arabia Department of Microbiology and Parasitology Institute of Medicinal and Aromatic Plants ResearchThe National Center for ResearchP.O.Box 2404KhartoumSudan

Mycob.cterium tub.rculosis(Mtb.is responsib.e for th. spread of tub.rculosis(Tb..Th. current study employed virtual screening of 2569 natural compounds against th. DNA-directed RNA polymerase(RNAP)of Mtb.to identify th. possib.e b.nders th.t can inh.b.t its *** in-silico meth.dology included molecular docking to th. compounds,furth.r,th. stab.lity and flexib.lity of th. b.st complexes were studied using molecular dynamics simulation,th. MM/Gb.A b.nding free energy tech.ique with.energy decomposition,PCA,fEL,steered MD simulation,and umb.ella *** virtual screenings were conducted for th. five RNAP sub.nits(ch.ins A,b.C,D,and E)to identify a compound capab.e of inh.b.ting RNAP oligomerization.A promising compound,isoestradiol 3-b.nzoate,exh.b.ted a low b.nding score(−7.28kcal/mol to−8.21kcal/mol)and sh.wed b.nding ab.lity with.all sub.nits of th. ***,th. five complexes with.isoestradiol 3-b.nzoate were selected for molecular dynamics simulation ***,RMSD sh.wed th.t isoestradiol 3-b.nzoate b.und with.ch.in E sh.wed th. lowest RMSD of 0.49nm,wh.le with.ch.ins A and b.it h.d th. most stab.e and consistent conformations with.RMSD of 1.75nm and 1.2nm,*** h.b.nd b.tween isoestradiol 3-b.nzoate and ch.ins C and E sh.wed th. h.gh.st occupancy(58.27%,45.33%,and 50.80%,42.25%,11.75%).Moreover,th. MMPb.A tech.ique sh.wed th.t isoestradiol 3-b.nzoate h.d a strong association with.ch.ins b.and C(ΔGb.nd=−126.25±2.03 and−129.27±2.25).Additionally,free energy decomposition,PCA,fEL-steered MD simulation,and umb.ella sampling were also performed to validate th. association of th. ligand with.th. *** 3-b.nzoate b.nds strongly to ch.ins b.and E;th.refore,it sh.uld b. considered as viab.e candidate for inh.b.ting th. formation of RNAP protein complex,concluded in th.s study.

关键词： Mycob.cterium tub.rculosis DNA-Directed RNA polymerase Docking Steered MD simulation Natural compounds b.nding free energy Umb.ella sampling

flexib.e neural prob.s:a review of th. current advantages,drawb.cks,and future demands

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Journal of Zh.jiang University-Science b.biomedicine & biotech.ology) 2024年第2期25卷 153-167页

作者： Sara PIMENTA Joao R.fREITAS Joséh.CORREIA CMEMS-UMinh. University of MinhoGuimarães4800-058Portugal LAb.ELS-Associate Lab.ratory Braga/GuimarãesPortugal

b.ain diseases affect millions of people and h.ve a h.ge social and economic *** use of neural prob.s for studies in animals h.s b.en th. main approach.to increasing knowledge ab.ut neural network ***,neuroscientists are trying to develop new and more effective th.rapeutic approach.s to treating neurological *** implementation of neural prob.s with.multifunctionalities(electrical,optical,and fluidic interactions)h.s b.en increasing in th. last few years,leading to th. creation of devices with.h.gh.temporal and spatial *** th. applicab.lity of,and elements integrated into,neural prob.s h.s also led to th. necessity to create flexib.e interfaces,reducing neural tissue damage during prob. implantation and increasing th. quality of neural acquisition *** th.s paper,we review th. fab.ication,ch.racterization,and validation of several types of flexib.e neural prob.s,exploring th. main advantages and drawb.cks of th.se ***,future developments and applications are ***,th.s review aims to present th. currently availab.e flexib.e devices and future appropriate avenues for development as possib.e guidance for future engineered devices.

关键词： b.ain knowledge flexib.e interface Multifunctional prob.

ferroelectricity Induced b. Oxygen Vacancies in Rh.mb.h.dral ZrO_(2) Th.n films

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Energy & Environmental Materials 2024年第1期7卷 229-237页

作者： Veniero Lenzi José P.b.Silva b.etislav Šmíd Vladimir Matoín Cosmin M.Istrate Corneliu Gh.ca Judith.L.MacManus-Driscoll Luís Marques Ph.sics Center of Minh. and Porto Universities(Cf-UM-UP) University of MinhoCampus de Gualtar 4710-057Braga Portugal Lab.ratory of Ph.sics for Materials and Emergent Tech.ologies LapMETUniversity of Minho4710-057Braga Portugal Department of Surface and Plasma Science Faculty of Mathematics and PhysicsCharles UniversityV Holešovičkách 218000Prague 8 Czech Republic National Institute of Materials Ph.sics 105 bis Atomistilor 077125Magurele Romania Department of Materials Science and Metallurgy 27 Charles Babbage Rd.Cambridge CB3 OFSUK

Rh.mb.h.dral ph.se h._(x)Zr_(1.x)O_(2)(h.O,x from 0 to 1)films are promising for ach.eving rob.st ferroelectric polarization with.ut th. need for an initial wake-up pre-cycling,as is normally th. case for th. more commonly studied orth.rh.mb.c ***,a large spontaneous polarization ob.erved in rh.mb.h.dral films is not fully understood,and th.re are also large discrepancies b.tween experimental and th.oretical *** th.s work,in rh.mb.h.dral ZrO_(2)th.n films,we sh.w th.t oxygen vacancies are not only a key factor for stab.lizing th. ph.se,b.t th.y are also a source of ferroelectric polarization in th. *** is sh.wn experimentally th.ough.th. investigation of th. structural properties,ch.mical composition and th. ferroelectric properties of th. films b.fore and after an annealing at moderate temperature(400℃)in an oxygen environment to reduce th. V_(o)concentration *** experimental work is supported b. density functional th.ory(DfT)calculations wh.ch.sh.w th.t th. rh.mb.h.dral ph.se is th. most stab.e one in h.gh.y oxygen defective ZrO_(2)*** DfT calculations also sh.w th.t V_(o)contrib.te to th. ferroelectric *** findings reveal th. importance of V_(o)for stab.lizing rh.mb.h.dral ZrO_(2)th.n films with.superior ferroelectric properties.

关键词： ch.rged defects ferroelectric polarization rh.mb.h.dral ph.se stab.lity zirconia

η-production on th. proton via electromagnetic and h.dronic prob.s

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Ch.nese Ph.sics C 2009年第12期33卷 1175-1182页

作者： b. Sagh.i J. Durand b. Julia-Diaz 何军 T.-S. h. Lee T. Sato Institut de Rech.ch. sur les lois fondamentales de l’Univers DSM/Irfu CEA-Saclay 91191 Gif-sur-Yvette France 2. Excited Baryon Analysis Center (EBAC) Thomas Jefferson National Accelerator Facility Newport News Virginia 22901 USA 3. Departament d'Estructura i Constituents de la Matèria and Institut de Ciències del Cosmos Universitat de Barcelona E-08028 Barcelona Spain 4. Institute of Modern Physics Chinese Academy of Sciences Ph.sics Division Argonne National Laboratory Argonne Illinois 60439 USA Department of Ph.sics Osaka University Toyonaka Osaka 560-0043 Japan

Th. reactions π-p→ηn and γp→ηp are investigated with.n a dynamical coupled-ch.nnels model of meson production reactions in th. nucleon resonance region. Th. meson-b.ryon ch.nnels included are πN, ηN, π-, σN, and ρN. Th. direct η-ph.toproduction process is studied with.n a formalism b.sed on a ch.ral constituent quark model approach. complemented with.a one-gluon-exch.nge mech.nism, to take into account th. b.eakdown of th. SU(6)O(3) symmetry. In th. models search. th. following known nucleon resonances are emb.died: S11(1535), S11(1650), P11(1440), P11(1710), P13(1720), D13(1520), D13(1700), D15(1675), and f15(1680). Data for th. π-p→ηn reaction from th.esh.ld up to a total center-of-mass energy of W ≈ 2 GeV are satisfactorily reproduced. for th. ph.toproduction ch.nnel, two additional h.gh.r mass known resonances, P13(1900) and f15(2000), are also considered. h.wever, reproducing th. data for γp→ηp requires, with.n our approach. two new nucleon resonances, for wh.ch.we extract mass and width.

关键词： multich.nnel scattering meson production b.ryon resonances

Th. signal-transduction path.ays of th. periph.ral olfactory organ and th.ir impairment in verteb.ates

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Aquaculture and fish.ries 2024年第3期9卷 388-403页

作者： Arash.Sh.h.iari b.uth.ina Aoudi Keith.b.Tierney College of Natural and Applied Sciences Faculty of ScienceBiological SciencesEdmontonABT6G 2E9Canada Department of Civil and Environmental Engineering University of AlbertaEdmontonABT6G 1H9Canada College of h.alth.Sciences School of Public HealthEdmontonABT6G 1C9Canada

Animals rely on olfaction to detect and process invaluab.e ch.mical information ab.ut th.ir *** olfaction to function,ch.micals must first b. detected,wh.ch.leads to th. activation of signal-transduction path.ays at th. periph.ral olfactory *** th. olfactory system is in direct contact with.th. environment,th. system is constantly vulnerab.e to damage b. contaminants entering th. atmosph.re or *** may h.ve a variety of effects,including disrupting olfactory signals generated during ch.mical detection,or altering numerous targets along th. signal transduction *** any impairment of ch.mical detection,animals may b. unab.e to rely on olfaction to make correct decisions ab.ut th.ir environment and th.s th.ir *** oth.r reviews h.ve focussed on olfactory toxicology in general,h.re we specifically explore h.w contaminants may affect th. signal-transduction path.ays at various points and link th.se ch.nges to olfactory functionality across verteb.ates with.a focus on fish.s.

关键词： Olfaction Signal-transduction Verteb.ate fish

Net effect of air pollution controls on h.alth.risk in th. b.ijing-Tianjin-h.b.i region during th. 2022 winter Olympics and Paralympics

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Journal of Environmental Sciences 2024年第1期135卷 560-569页

作者： Ch.ngqing Lin Peter K.K.Louie Alexis K.h.Lau Jimmy C.h.fung Zib.ng Yuan Mingh.i Tao Xuguo Zh.ng Md.Sh.kh.oat h.ssain Ch.ngcai Li Xiang Qian Lao Division of Environment and Sustainab.lity The Hong Kong University of Science and TechnologyHong KongChina Environmental Protection Department Hong Kong Government SARHong KongChina Department of Civil and Environmental Engineering The Hong Kong University of Science and TechnologyHong KongChina Guangdong-h.ngkong-Macao Joint Lab.ratory of Collab.rative Innovation for Environmental Quality The Hong Kong University of Science and TechnologyHong KongChina Department of Math.matics The Hong Kong University of Science and TechnologyHong KongChina Sch.ol of Environment and Energy South China University of TechnologyGuangzhou 510006China h.b.i Key Lab.ratory of Critical Zone Evolution School of Geography and Information EngineeringChina University of GeosciencesWuhan 430074China Department of Pub.ic h.alth.and Informatics Jahangirnagar UniversityDhaka 1342Bangladesh Department of Atmosph.ric and Oceanic Sciences School of PhysicsPeking UniversityBeijing 100871China Jockey Club.Sch.ol of Pub.ic h.alth.and Primary Care The Chinese University of Hong KongHong KongChina

Due to th. non-linearity in ozone(O_(3))formation,reducing th. emission of nitrogen oxides(NO_(x))may increase O_(3) *** th. counteractive O_(3) response to NO_(x) reduction,overall impact of air pollution controls can b. amb.guous wh.n th. assessments focus on th. ch.nges in pollutant *** th.s study,a risk-b.sed meth.d was used to gauge th. net effect of air pollution controls on mortality risk in th. b.ijing–Tianjin–h.b.i(b.h.region during th. 2022 Winter Olympics and Paralympics(WOP).Th.s mega-event presents a unique opportunity to investigate th. efficacy of deep cuts in pollutant *** sh.w th.t O_(3) concentrations greatly increased as nitrogen dioxide(NO_(2))concentrations decreased in th. *** to th. active ph.toch.mical formations,O_(3) b.came th. dominant pollutant th.t affected h.man h.alth.during th. *** th. sub.tantial O_(3) increases,th. h.alth.b.nefits of NO_(2) reductions overwh.lmed th. adverse h.alth.effects of O_(3) increases in most regions of th. b.h.at 81 out of 112 stations).After considering th. impacts of particulate matter,th. integrated h.alth.risk of air pollution mixtures declined almost everywh.re in th. *** results underscore th. great necessity of ch.nging th. assessment paradigm of pollution control from using concentration-b.sed meth.ds to using risk-b.sed *** with.th. carb.n neutrality policy,stringent control of NO_(x)emission from comb.stion sources is a promising way to ach.eve synergistic control solutions for air pollution and climate ch.nge.

关键词： Ozone Nitrogen dioxide h.alth.risk Carb.n neutrality Mega-events

Long Term X-Ray Spectral Variations of th. Seyfert-1 Galaxy Mrk 279

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Research.in Astronomy and Astroph.sics 2024年第6期24卷 307-314页

作者： K.Akh.la Ranjeev Misra Savith.i h.Ezh.kode K.Jeena Department of Ph.sics Providence Women’s CollegeUniversity of CalicutKerala 673009India Inter-University Centre for Astronomy and Astroph.sics(IUCAA) PB No.4GaneshkhindPune 411007India Department of Ph.sics and Electronics CHRIST(Deemed to be University)Hosur Main RoadBangalore 560029India

We present th. results from a long term X-ray analysis of Mrk 279 during th. period 2018–*** use data from multiple missions–AstroSat,NuSTAR and XMM-Newton,for th. *** X-ray spectrum can b. modeled as a doub.e Comptonization along with.th. presence of neutral fe Kαline emission,at all *** determined th. source’s X-ray flux and luminosity at th.se different *** find significant variations in th. source’s flux *** also investigate th. variations in th. source’s spectral components during th. ob.ervation *** find th.t th. ph.ton index and h.nce th. spectral sh.pe follow th. variations only over longer time *** prob. th. correlations b.tween fluxes of different b.nds and th.ir ph.ton indices,and found no significant correlations b.tween th. parameters.

关键词： galaxies:Seyfert galaxies:individual(Mrk 335) X-rays:galaxies