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在低质饲料中添加糖蜜及天然蛋白质饲喂繁殖母牛评价

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饲料广角 1991年第4期 45-46页

作者：陈金文 f.m.pate

在冬季对给饲低质饲料的白来福母牛(514交配)进行了3、4年添加剂试验,以比较糖蜜(简称m,含粗蛋白6％)、糖蜜尿素(mU;CP17.5％;由92％糖蜜、4％尿素及4％水组成)和糖蜜棉籽尿素混合物

关键词：母牛添加剂犊牛蛋白质天然

Design,optimization,and characterization of an in-situ pore-forming system for controlled delivery of paliperidone

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medicine in Novel Technology and Devices 2024年第1期21卷 71-79页

作者： Priya pate Bhumi Ladani Gayatri patel Ramanbhai patel College of Pharmacy Charotar University of Science and TechnologyCHARUSAT–CampusChanga388421AnandGujaratIndia

The purpose of the current investigation was to develop a pharmaceutical equivalent osmotic drug delivery formulation of Paliperidone(PLD)in the form of controlled porosity osmotic pump tablets(CPOT)in order to keep the drug's steady state concentration in the *** helps to achieve the greatest therapeutic benefit with the fewest side *** the purpose of identifying various formulation attributes,preliminary trials were *** design was used to study the influence of seven input factors namely drug to polymer ratio,polymer 1(HPmC K100 m)to polymer 2(HPmC K15m),drug to total osmogens,coating level,amount of pore former,concentration of ethyl cellulose and amount of plasticizer on dependent variable similarity factor(f2).Utilizing the minitab 17,data analysis was *** similarity factor(f2)was computed using the osmotic tablet reference product INVEGA®.The findings demonstrate that each of the seven independent variables significantly affects the similarity *** optimized batch,both core and coated tablets showed acceptable pharmaco-technical *** release profile of the optimized batch tablets was found to be similar to that of reference product with good zero-order release *** release was observed through the channels formed by in-situ pores on tablet surface performed using *** the results it can be concluded that prepared CPOT of PLD was found pharmaceutical equivalent with commercial product which is cost effective and fully compliance with cGmP.

关键词： Controlled release pH-independent release Similarity factor Pharmaceutical equivalent Reference product

Control and vibration analyses of a sandwich doubly curved micro-composite shell with honeycomb, truss, and corrugated cores based on the fourth-order shear deformation theory

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Applied mathematics and mechanics(English Edition) 2024年第10期45卷 1773-1790页

作者： f.SHIRDELAN m.mOHAmmADImEHR f.BARGOZINI Department of Solid mechanics Faculty of Mechanical Engineering University of Kashan

Curved shells are increasingly utilized in applied engineering due to their shared characteristics with other sandwich structures, flexibility, and attractive appearance. However, the inability of controlling and regulating vibrations and destroying them afterward is a challenge to scientists. In this paper, the curve shell equations and a linear quadratic regulator are adopted for the state feedback design to manage the structure vibrations in state space forms. A five-layer sandwich doubly curved micro-composite shell, comprising two piezoelectric layers for the sensor and actuator, is modeled by the fourth-order shear deformation theory. The core(honeycomb, truss, and corrugated) is analyzed for the bearing of transverse shear forces. The results show that the honeycomb core has a greater effect on the vibrations. When the parameters related to the core and the weight percentage of graphene increase, the frequency increases. The uniform distribution of graphene platelets results in the lowest natural frequency while the natural frequency increases. furthermore, without taking into account the piezoelectric layers,the third-order shear deformation theory(TSDT) and fourth-order shear deformation theory(fOSDT) align closely. However, when the piezoelectric layers are incorporated,these two theories diverge significantly, with the frequencies in the fOSDT being lower than those in the TSDT.

关键词： 74f15 corrugate core doubly curved shell honeycomb micro-composite O343 truss vibration and control

The viscous strip approach to simplify the calculation of the surface acoustic wave generated streaming

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Applied mathematics and mechanics(English Edition) 2024年第4期45卷 711-724页

作者： f.JAZINI DORCHEH m.GHASSEmI fuel Cells and Nano Systems(fCNS)Laboratory Department of Mechanical EngineeringK.N.Toosi University of TechnologyTehran 19697Iran

In recent decades,the importance of surface acoustic waves,as a biocompatible tool to integrate with microfluidics,has been proven in various medical and biological *** numerical modeling of acoustic streaming caused by surface acoustic waves in microchannels requires the effect of viscosity to be considered in the equations which complicates the *** this paper,it is shown that the major contribution of viscosity and the horizontal component of actuation is concentrated in a narrow region alongside the actuation *** the inviscid equations are considerably easier to solve,a division into the viscous and inviscid domains would alleviate the computational load *** particles'traces calculated by this approximation are excellently alongside their counterparts from the completely viscous *** is also shown that the optimum thickness for the viscous strip is about 9-fold the acoustic boundary layer thickness for various flow patterns and amplitudes of actuation.

关键词： surface acoustic wave microfluidics numerical simulation particle tracing acoustic streaming

Intraoperative glioblastoma surgery-current challenges and clinical trials:An update

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Cancer Pathogenesis and Therapy 2024年第4期2卷 256-267页

作者： Vimal pate Vishal Chavda Department of Pharmaceutics Anand Pharmacy CollegeAnandGujarat 388001India Department of Pathology Stanford School of MedicineStanford University Medical CenterStanfordCA 94305USA Department of medicine MultispecialtyTrauma and ICCU CenterSardar HospitalAhmedabadGujarat 382350India

Surgical excision is an important part of the multimodal therapy strategy for patients with glioblastoma,a very aggressive and invasive brain *** major advances in surgical methods and technology have been accomplished,numerous hurdles remain in the field of glioblastoma *** purpose of this literature review is to offer a thorough overview of the current challenges in glioblastoma *** reviewed the difficulties associated with tumor identification and visualization,resection extent,neurological function preservation,tumor margin evaluation,and inclusion of sophisticated imaging and navigation *** and resolving these challenges is critical in order to improve surgical results and,ultimately,patient survival.

关键词： Glioblastoma Infiltrative tumor Awake craniotomy Evoked potentials Neuroimaging Navigation

Langmuir-Schaefer film Investigation and Density functional Theory Band Gap Calculations of Calix[n]arene-Para-Aminobenzoic Acid for Drug Nanosensor Application

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Journal of Wuhan University of Technology(materials Science) 2024年第5期39卷 1311-1318页

作者： WONG Yeong Yi f L Supian A Radzwan m musa N f N Abd Karim Department of Physics Sultan Idris Education UniversityTanjong Malim 35900Malaysia Department of Chemistry Sultan Idris Education UniversityTanjong Malim 35900Malaysia

Calix[n]arenes was utilized to detect PABA,the primary sunscreen *** study investigates the interaction of calix[4]arene(C4),calix[6]arene(C6),and PABA using the Langmuir method and first-principle density functional theory(DfT).Using the Langmuir-Schaefer(LS)technique,an ultrathin film composed of calix[n]arenes and their complexes with PABA was deposited on various *** on the Langmuir study,the PABA molecule was bonded to the lower rims of both C4 and C6 with the host-guest ratio of 1:*** of the LS films formed were then characterized by ultravioletvisible spectroscopy(UV-Vis),fourier-transform infrared spectroscopy(fTIR)and carbon,hydrogen,nitrogen,sulfur elemental analyzer(CHNS).The band gap reduction obtained in the DfT study denotes the charge transfer interaction with promising reactivity between the calix[n]arenes and *** sensing of PABA by C4 and C6 is successful based on the formation of bonding between them due to the hosts’effective trapping *** outcomes of this study could be applied to drug delivery systems for future pharmaceutical and medical applications.

关键词： calix[n]arenes band gap density functional theory Langmuir-Schaefer PABA sensor

morphological traits explain the individual position within resource-consumer networks of a Neotropical marsupial

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Current Zoology 2024年第4期70卷 453-464页

作者： Nicholas f.de Camargo Hernani f.m.de Oliveira Juliana f.Ribeiro Amabilio J.A.de Camargo Emerson m.Vieira Laboratorio de Ecologia de Vertebrados Departamento de EcologiaInstituto de Ciencias BiologicasUniversidade de BrasiliaCP 04457BrasiliaDF70910-900Brazil Departamento de Zoologia Setor de Ciencias BiologicasUniversidade Federal do ParanaAvenida Coronel Francisco Heraclito dos Santos100CuritibaPR81531980Brazil Embrapa Cerrados Rodovia BR020km 18CP 08223PlanaltinaDE73310-970Brazil

Knowledge regarding the influence of individual traits on interaction patterns in nature can help understand the topological role of individuals within a network of intrapopulation *** tested hypotheses on the relationships between individuals'positions within networks(specialization and centrality)of 4 populations of the mouse opossum Gracilinanus agilis and their traits(i.e.,body length,body condition,tail length relative to body length,sex,reproductive condition,and botfly parasitism)and also seasonal effects in the Brazilian *** with lower body length,better body condition,and relatively shorter tail were more specialized(i.e.,less connected within the network).Individuals were also more specialized and less connected during the warm-wet *** relationship between individuals'position in the network and body traits,however,was independent of *** propose that specialization may arise not only as a result of preferred feed-ing strategies by more capable individuals(i.e.,those with better body condition and potentially prone to defend and access high-quality food resources)but alsobecause of morphological ***/younger individuals(consequently with less experience in foraging)and short-tailed individuals(less skilled to explore the vertical strata of the vegetation)would feed only on a subset of the available food resources and consequently become more ***,individuals are more specialized during the warm-wet season because of high competition(population-dense period)and higher ecological opportunities(resource-rich period).Therefore,our study reveals the relevance of individual traits inshaping interactionpatternsandspecialization inpopulations.

关键词： bodytraits centrality Cerrado Gracilinanus agilis seasonality specialization.

A review of ethnobotanical studies reveals over 500 medicinal plants in mindanao,Philippines

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Plant Diversity 2024年第5期46卷 551-564页

作者： Joeime f.meñiza monica m.Pasco Jemer A.Alimbon Department of Teacher Education UM Tagum CollegeTagum City8100Davao del Norte Philippines

medicinal plants have long been used to treat various diseases in both indigenous and non-indigenous populations of mindanao,***,we extracted data from ethnobotanical studies to compile a comprehensive list of these medicinal plants and identify how and for what purpose they are most commonly *** identified 530 verified medicinal plant species across 372 genera in 118 *** two most frequently cited species were Euphorbia hirta and Psidium *** most represented family was fabaceae and the most represented genus was ficus.A total of 28 medicinal plant species are designated as threatened at the national or global level;of these,11 are endemic to the *** plant preparations most commonly use leaves for oral administration to treat various diseases such as digestive issues,including *** study underscores the need for further ethnobotanical investigations,particularly in areas lacking *** also emphasizes the need for conservation of threatened and endemic medicinal plants to ensure sustainable utilization of this valuable resource.

关键词： Ethnobotany medicinal plants mindanao Philippines

Carbon monoxide as C1 Building Block in fine Chemical Synthesis

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Chinese Journal of Chemistry 2024年第2期42卷 199-221页

作者： Rui m.B.Carrilho mario J.f.Calvete Gabor mikle Laszlo Kollar mariette m.Pereira University of Coimbra Coimbra Chemistry CentreDepartment of ChemistryRua Larga3004-535 CoimbraPortugal Department of General and Inorganic Chemistry and ELKH-PTE Research Groupfor Selective Chemical Syntheses University of PecsIfjusag utja 6H-7624 PecsHungary

Carbon monoxide(CO)has become one of the most relevant and versatile renewable C1 building blocks for chemical synthesis,especially in the fine chemicals industry,due to the development of efficient and selective catalysts for its *** this review,we present a comprehensive critical analysis of the last 10 years literature on the use of CO as a renewable feedstock for fine chemicals *** review is organized by type of catalytic reaction,namely alkene and alkyne carbonylation,hydroformylation,carbonylation of aryl halides,carbonylative cross-coupling and C-H *** examples of the synthesis of relevant building blocks and/or known pharmaceuticals are *** is placed on examples of utilizing CO as the C1 building block in one or more catalytic *** catalyst used and the reaction conditions are consistently presented throughout all of the examples.

关键词： Carbon monoxide fine chemicals Carbonylation Hydroformylation C-H functionalization