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Goal-directed fluid therapy in gastrointestinal cancer surgery:A prospective randomized study

Journal of Acute Disease 2022年第2期11卷 52-58,I0001页

作者： Duygu Akyol Zafer Cukurova evrim kucur tulubas GüneşÖzlem Yıldız Mehmet Süleyman Sabaz Department of Anesthesiology and Reanimation BaşakşehirÇam and Sakura City HospitalIstanbulTurkey Department of Anesthesiology and Reanimation Bakirkoy Dr.Sadi Konuk Training and Research HospitalUniversity of Health SciencesIstanbulTurkey Department of Critical Care Medicine Marmara University Pendik Training and Research HospitalMarmara University School of MedicineIstanbulTurkey

Objective:To investigate the effects of perioperative goal-directed fluid therapy(GDFT)on intraoperative fluid balance,postoperative morbidity,and ***:This is a prospective randomized study,and 90 patients who underwent elective open gastrointestinal cancer surgery between April 2017 and May 2018 were *** were randomized into 2 groups that received liberal fluid therapy(the LFT group,n=45)and goal-directed fluid therapy(the GDFT group,n=45).Patients’Colorectal Physiologic and Operative Severity Score for the enUmeration of Mortality and Morbidity(CR-POSSUM)physiological score,Charlson Comorbidity Index(CCI),perioperative vasopressor and inotrope use,postoperative AKIN classification,postoperative intensive care unit(ICU)hospitalization,hospital stay,and 30-day mortality were ***:The volume of crystalloid used perioperatively and the total volume of fluid were significantly lower in the GDFT group compared to the LFT group(P0.05).Conclusion:Although GDFT was demonstrated to be a good alternative method to LFT in open gastrointestinal cancer surgery,and it can prevent perioperative fluid overload,and the postoperative results are comparable in the two groups.

关键词： Goal-directed fluid therapy Liberal fluid therapy Stroke volume variation Open gastrointestinal cancer surgery

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