检索结果-南通市图书馆

Synthesis and characterization of monosize magnetic poly(glycidyl methacrylate) beads

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

China Particuology 2007年第1期5卷 174-179页

作者： evrim Banu Alt■ntas■ Lokman Uzun Adil Denizli Department of Chemistry Biochemistry Division Hacettepe University Ankara Turkey

Monosize, 1.6 μm, magnetic beads of poly（glycidyl methacrylate） [M-poly（GMA）], were prepared by dispersion polymerization in the presence of Fe3O4 nano-powder. Monosize M-poly（GMA） beads were characterized by swelling tests, density measurements, electron spin resonance （ESR）, vibrating sample magnetometer （VSM） and scanning electron microscopy （SEM）. The characteristic functional groups of M-poly（GMA） beads were analyzed by Fourier transform infrared spectrometer （FTIR）. The M-poly（GMA） beads are highly uniform in size and have a spherical shape and non-porous structure. Polydispersity index （PDI） of M-poly（GMA） beads was calculated to be around 1.008. The hydrated density of the M-poly（GMA） beads measured at 25 ℃ was 1.14 g/cm^3. The content of oxirane groups on the surface of the M-poly（GMA） sample was found to be 3.46 mmol/g by using perchloric acid titration. The specific surface area of the M-poly（GMA） beads was determined to be 3.2 m^2/g. The equilibrium swelling ratio was 52%. The volume fraction of magnetite nanopowder in the M-poly（GMA） beads was found to be 4.5%. The g factor, that can be considered as a quantity characteristic of the molecules in which the unpaired electrons are located, was found to be 2.28 for M-poly（GMA）. The external magnetic field at resonance was calculated to be 2055 Gs which was found sufficient to excite all of the dipole moments present in 1.0 g of M-poly（GMA） sample.

关键词： Polyglycidyl methacrylate Monosize beads Magnetic materials

Retinal neurodegeneration in metabolic syndrome:a spectral optical coherence tomography study

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2023年第2期16卷 224-232页

作者： evrim Polat Ekrem Celik Mesut Togac Afsun Sahin Department of Ophthalmology Tekirdag City HospitalTekirdag 59100Turkey Department of Ophthalmology Tekirdag Namik Kemal UniversityFaculty of MedicineTekirdag 59100Turkey Department of Ophthalmology Koc University Medical SchoolIstanbul 34010Turkey Research Center for Translational Medicine Koc UniversityIstanbul 34450Turkey

AIM:To evaluate the effects of metabolic syndrome(Met S)on retinal neurodegeneration by optical coherence tomography(OCT).METHODS:Patients diagnosed as Met S were compared with the age and sex-matched healthy control group(CG).Waist circumference measurements,fasting serological biochemical tests,and systemic blood pressures of all participants were *** Met S group was divided into 3 subgroups according to the number of Met S components:hypertension,diabetes mellitus,dyslipidemia(low-,high-density lipoprotein,hypertriglyceridemia),and visceral obesity findings;3-component Met S3,4-component Met S4,and all-component Met *** patients underwent complete eye examination and spectral OCT retinal ***:Totally 58 eyes of 58 patients were included in the Met S group and 63 eyes of 63 age and sex-matched healthy subjects were included in *** S group was composed of 22 subjects in Met S3,21 subjects in Met S4,and 15 subjects in the Met S5 *** foveal thickness(Met S,218.7±23.1μm vs CG,228.8±21.9μm,P=0.015),mean inferior(Met S,283.4±17.0μm vs CG,288.7±38.4μm,P=0.002),superior(Met S,287.0±18.5μm vs CG 297.3±17.1μm,P=0.001),nasal(Met S 287.3±16.7μm vs CG 297.9±13.9μm,P=0.000)and temporal(274.5±17.6μm vs CG 285.6±13.6μm,P=0.000)thickness in the 3 mm Early Treatment of Diabetic Retinopathy Study(ETDRS)circle was significantly lower in the Met S *** was no statistically significant difference in the mean inferior,superior,nasal,and temporal thickness of 6 mm ETDRS circle,total macular volume,peripapillary and macular retinal nerve fiber layer,macular ganglion cell layer with inner plexiform layer,and ganglion cell *** statistically significant difference was found in these values between the Met S3,Met S4,and the Met S5 ***:A significant reduction in central macular region thickness in Met S is detected and macular thickness is more susceptible to Met S induced neurodegeneration than peripapillary retinal nerve fiber

关键词： metabolic syndrome retinal neurodegeneration hypertension diabetes mellitus dyslipidemia optical coherence tomography

Bio-fabrication of liver cancer stem cells and testing of gemcitabine

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Cancer Metastasis and Treatment 2023年第1期9卷 497-505页

作者： evrim Cevik Omer Erdogan Ozge Cevik Department of Machinery and Metal Technologies Aydin Adnan Menderes UniversityKocarli Vocational High SchoolAydin 09970Turkey Department of Medicinal Biochemistry Aydin Adnan Menderes UniversitySchool of MedicineAydin 09010Turkey

Aim:Cancer stem cells are cell populations that are essential in drug resistance and cancer *** liver cancer cells exhibit the characteristics of cancer stem cells,and it is crucial to study the activities and interactions of drugs in these ***7 is a human liver cancer cell with stem cell biomarkers and is used with induced pluripotent stem cells to form various cancer organoids through encapsulation *** to their ease of use without animal testing,bio-fabrication studies of cell-encapsulated models have gained importance in the pharmaceutical industry in recent *** study aimed to biofabricate Huh7 human liver cancer stem cells by alginate encapsulation and test gemcitabine’s ***:Huh7 cells were encapsulated with alginate(0.8%w/v)and fibronectin,and their viability was evaluated with 3.2μM gemcitabine on days 1,3,6,9,and ***,gene expressions of stem cell markers CD90 and AFP were evaluated in encapsulated Huh7 cells by *** addition,IL-6 secretion in the cell medium was measured by ELISA for the tumor ***:Encapsulation of Huh7 cells was found to maintain their viability and stem cell properties for up to 12 *** addition,alginate-encapsulated Huh7 cells were bio-fabricated to demonstrate long-term gemcitabine *** the effect of the gemcitabine was evaluated in alginate-encapsulated Huh7 cells,CD90 and AFP mRNA levels were significantly reduced in the cells and IL-6 secretion was decreased in the tumor ***:This study demonstrated that bio-fabrication of alginate-encapsulated Huh7 cells is a novel approach for long-term drug testing in liver cancer ***-fabricated alginate-encapsulated cancer stem cells may be a cheaper and faster method for the testing of many drugs.

关键词： Bio-fabrication cancer stem cells gemcitabine liver cancer alginate beads

Superior labrum anterior to posterior lesions of the shoulder: Diagnosis and arthroscopic management

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Orthopedics 2014年第3期5卷 344-350页

作者： Nuri Aydin evrim Sirin Alp Arya Department of Orthopedics and Traumatology Cerrahpasa Medical SchoolUniversity of Istanbul34116 IstanbulTurkey FSM Research and Teaching Hospital Turkish Ministy of Health34400 IstanbulTurkey

After the improvement in arthroscopic shoulder surgery,superior labrum anterior to posterior(SLAP)tears are increasingly recognized and treated in persons with excessive overhead activities like *** potential mechanisms for the pathophysiology of superior labral tears have been *** diagnosis of this condition can be possible by history,physical examination and magnetic resonance imaging *** treatment of type 1 SLAP tears in many cases especially in older patients is non-operative but some cases need arthroscopic *** arthroscopic management of type 2 lesions in older patients can be biceps tenodesis,but young and active patients like throwers will need an arthroscopic *** results of arthroscopic repair in older patients are not *** purpose of this study is to perform an overview of the diagnosis of the SLAP tears and to help decision making for the surgical management.

关键词： Superior labrum anterior to posterior tear Glenoid labrum Arthroscopy Repair Shoulder

A Research on QFD-＂House of Brand＂ in Fashion Industry

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Business Review 2016年第4期15卷 207-213页

作者： evrim Kabukcu Celal Bayar University Manisa Turkey

Fashion continues to be an area that reflects the increasing popularity of different theoretical and practical approaches of researchers from different disciplines. Due to the rapid cycles of fashion, sustainable products and processes in terms of technical creativity and innovative approach are needed. In this context, fashion marketing emerges as an integrative marketing application with its both technical and social aspects by taking potential customers center that symbolize rapid change and creativity of fashion products. In this study, QFD-House of Brand was designed with Quality Function Deployment （QFD） approach. In this context, the experts （focus group） in Fashion Industry evaluated the selected fashion brand and its selected products by prioritizing the criteria. These evaluations were used in QFD-House of Brand. Thus, technical and social aspects of fashion industry were analysed together. By this technique, QFD-House of Brand established in relation to products and brand was interpreted and optimization suggestions were presented in accordance with the findings of the research. In addition, suggestions on sustainability and optimization of brand equity in fashion industry were provided.

关键词： brand equity fashion industry product quality function deployment sustainability

Conduction Mechanism Analysis of Inversion Current in MOS Tunnel Diodes

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Materials Sciences and Applications 2013年第12期4卷 794-801页

作者： Ayse evrim Saatci Orhan Ozdemir Kubilay Kutlu Department of Physics Yildiz Technical UniversityIstanbulTurkey

Self inversion issue and excess capacitance phenomenon were observed for the first time in relatively thick silicon dioxide (SiO2) in the form of MOS (metal(Al)/SiO2/p type crystalline silicon) structure. Both phenomena were based on minority carriers (electrons in this case) and studied through DC current-applied bias voltage (I-V) and AC admittance measurements in dark/light condition as a function of ambient temperature (295 - 380 K). Either of the cases was the departure of traditional MOS analysis, manifesting themselves in the inversion regime of MOS diode. Increase in frequency/temperature/light intensity within dark and light conditions led to weaken the maxima of hump in C-V curves and finally turned into deep depletion mode after exceeding threshold value of frequency/temperature/light intensity. In resumed conditions, supplementary I-V measurements were carried out to describe the generation and conduction mechanism(s) for minority carriers (electrons).

关键词： Excess Capacitance MOS Selfly Inverted Region Tunneling Based Inversion Currents

Inhibition of Ehrlich ascites carcinoma growth by melatonin:Studies with micro-CT

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Oncology Research 2024年第1期32卷 175-185页

作者： SEHER YILMAZ ZÜLEYHA DOĞANYIĞIT MERT OCAK evrim SUNA ARIKAN SÖYLEMEZ ASLI OKAN OFLAMAZ SÜMEYYE UÇAR ŞÜKRÜATEŞ AMMAD AHMAD FAROOQI Department of Anatomy Faculty of MedicineYozgat Bozok UniversityYozgatTurkey Department of Mechanical and Aerospace Engineering Case Western Reserve UniversityClevelandOhioUSA Department of Histology and Embriology Faculty of MedicineYozgat Bozok UniversityYozgatTurkey Department of Anatomy Faculty of DentistryAnkara UniversityAnkaraTurkey Department of Medical Biology Faculty of MedicineAfyonkarahisar Health Sciences UniversityAfyonTurkey Department of Anatomy Faculty of MedicineErciyes UniversityKayseriTurkey Department of Molecular Oncology Institute of Biomedical and Genetic Engineering(IBGE)IslamabadPakistan

Melatonin is a versatile indolamine synthesized and secreted by the pineal gland in response to the photoperiodic information received by the retinohypothalamic signaling *** has many benefits,such as organizing circadian rhythms and acting as a powerful *** aimed to show the antitumor effects of melatonin in both in vivo and in vitro models through the mammalian target of rapamycin(mTOR)signaling pathway and the Argyrophilic Nucleolar Regulatory Region(AgNOR),using the Microcomputed Tomography(Micro CT).Ehrlich ascites carcinoma(EAC)cells were administered into the mice by subcutaneous *** with solid tumors were injected intraperitoneally with 50 and 100 mg/kg melatonin for 14 *** measurements for the taken tumors were made with micro-CT imaging,immunohistochemistry(IHC),real-time polymerase chain reaction(PCR)and ***,the tumor tissue volume in the Tumor+100 mg/kg melatonin group was significantly lower than that in the other groups in the data obtained from micro-CT *** the IHC analysis,the groups treated with Tumor+100 mg/kg melatonin were compared when the mTOR signaling pathway and factor 8(F8)expression were compared with the control *** was determined that there was a significant decrease(p<0.05).Significant differences were found in the total AgNOR area/nuclear area(TAA/NA)ratio in the treatment groups(p<0.05).Furthermore,there were significant differences between the amount of mTOR mRNA for the phosphatidylinositol 3-kinase(PI3K),AKT Serine/Threonine Kinase(PKB/AKT)genes(p<0.05).Cell apoptosis was evaluated with Annexin V in an in vitro study with different doses of melatonin;It was observed that 100µg/mL melatonin dose caused an increase in the apoptotic cell *** this study,we have reported anti-tumor effects of melatonin in cell culture studies as well as in mice *** characterization of the melatonin-mediated cancer inhibitory effects will be valuable in advanc

关键词： Signaling pathway Apoptosis Real-time PCR AgNOR

Crescentic glomerulonephritis in children:a single centre experience

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Pediatrics 2016年第2期12卷 225-230页

作者： Sare GülfemÖzlü AysunÇaltık Özlem Aydoğ Mehmet Bülbül Gülay Demircin evrimÇakıcı Nilüfer Arda AyşeÖner Department of Pediatric Nephrology Dr Sami Ulus Childrens and Maternity HospitalAnkaraTurkey Department of Pathology Sami Ulus Childrens and Maternity HospitalAnkaraTurkey

Background:Crescentic glomerulonephritis(CsGN)is characterized by crescents in 50%or more of glomeruli and clinically by a sudden and progressive decline in renal ***:We evaluated the etiology,clinical features,prognostic factors and long-term outcome of *** January 2000 and December 2010,45 children(26 girls,19 boys)with biopsy-proven CsGN(>50%crescents)were investigated ***:The mean age of the patients was 130.86±33.77 *** mean duration of symptoms prior to diagnosis was 26±12 days(4-40 days).Most of the children had hypertension(62.2%),macroscopic hematuria(73.3%),oligoanuria(44.4%),edema(51.1%)and purpuric rash(40%)at *** final clinical status of the patients was complete remission(n=21),partial remission(n=5)or chronic kidney disease(n=19).Adverse outcomes were significantly associated with a long duration between the onset of symptoms and treatment(P=0.038),the presence of oligoanuria(P=0.006),a severe decreased glomerular filtration rate(GFR75%)(P=0.03),and the ratio of fi brous crescents(P=0.015).Conclusion:The outcome of CsGN in children continues to be poor,and it should be treated as a renal emergency.

关键词： glomerulonephritis renal biopsy renal failure

A Modified Selective Medium Containing Benzalkonium Chloride (BKC) for the Isolation of <i>Pseudomonas aeruginosa</i>from Raw Milk

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food and Nutrition Sciences 2012年第7期3卷 947-950页

作者： Aylin Akoglu evrim Gunes Altuntas Gokce Polat Yemis Department of Food Engineering Faculty of Engineering University of Ankara Diskapi Ankara 06110 TURKEY Institute of Biotechnology University of Ankara Golbasi Ankara 06830 TURKEY

A modified selective medium (modified Cetrimide Agar, mCA) consisting of 200 μg/mL benzalkonium chloride (BKC) was developed for the isolation of Pseudomonas aeruginosa from raw milk. Initially, a total of 55 isolates were obtained from 14 raw milk samples collected from several dairy plants in Ankara, Turkey. Among these isolates, 19 were identified as Pseudomonas aeruginosa, 28 as Pseudomonas fluorescens, 4 as Acinetobacter baumannii, 2 as Enterobacter intermedium, 1 asEnterobacter agglomerans, and 1 as Escherichia coli using Microbact biochemical test kit. BKC was chosen as a selective agent to suppress growth of competitive flora because it is very effective against a wide range of Gram-negative bacteria while P. aeruginosa is resistant. MICs (minimum inhibitory concentration) for BKC were determined by agar dilution method. The concentration of 200 μg/mL BKC inhibited competitive flora, while 90% of P. aeruginosa strains were resistant. When the results of enumeration of P. aeruginosa and other Gram (-) bacteria in Cetrimide Agar (CA) and mCA were compared, it was observed that mCA was more selective than the standard CA in preventing the growth of competitive flora especially of P. fluorescens.

关键词： P. aeruginosa Benzalkonium Chloride (BKC) Modified Cetrimide Agar Raw Milk