检索结果-南通市图书馆

Viral Acute Respiratory Infections in Central African Republic Children: Epidemiological and Clinical Aspects

Open Journal of Pediatrics 2022年第2期12卷 332-346页

作者： Jean Chrysostome Gody Brice Olivier Bogning Mejiozem Ghislain Franck Houndjahoue Vanessa Iris Gaspiet Sonny Mario Giobbia Pierpaolo Grisetti Cristina Ceresoli Deborah Nguimba Raffaella Marino Sandra Garba Ouangole Wasianga Kendewa Festus Regis Mbrenga evodie pierrette kakouguere Ida Maxime Kangale-Wando Emmanuel Nakoune Centre Hospitalier Universitaire Pédiatrique de Bangui (CHUPB) Bangui Central African Republic Faculté des Sciences de la Santé (FACSS) Université de Bangui Bangui Central African Republic Médecins avec l’Afrique CUAMM International NGO Padova Italy Associazione Amici Per Il Centrafrica ODV Limido Comasco Italy Institut Pasteur de Bangui Bangui Central African Republic

Background: Acute respiratory infections (ARI) are recognized as an important cause of morbidity, mortality, and hospitalization among children in developing countries. Objectives: To identify the respiratory viruses circulating in Central African children before the SARS-COV2 pandemic and to assess the clinical manifestations. Methodology: This is a cross-sectional, descriptive, multicenter study, run from March 1, 2019, to March 31, 2020. Children aged 28 days to 15 year-old, with respiratory symptoms ≤10 days had been included. Nasopharyngeal swabs were taken and sent to the Institute Pasteur in Bangui (WHO National Referral Center for influenza). Virus research was done by cell and molecular culture techniques. Data were recorded and processed with Access 2019 software, then analyzed with STATA version 14 software. Chi-square test and ANOVA test were used to compare proportions at the p 0.05 threshold. Results: Out of 659 children included during the study period, viruses were identified in 231 children, for an overall positivity rate of 35.05% (231/659). Rhinoviruses (RV) and influenza viruses were found in 66.23% and 16.88% respectively. Virus-virus co-infections were found in 10 (10/231) children (4.32%). Children under 5 years of age were more represented (78.60%). The main reasons for consultation were: fever (96.20%), cough (95.45%), runny nose (78.5%), and breathing difficulty (30.50%). ILI (Influenza-Like Illness) was found in 71.02% versus 28.98% of SARI (Severe Acute Respiratory Infection). There was a statistically significant association between age 5 years and severity of acute respiratory infection (p = 0.001). The outcome was known for the 122 children at the CHUPB site with a mortality rate of 17.21% (n = 21). Conclusion: Viral ARI is common in children in Central African Republic. Care givers should think about it in order to reduce the inappropriate prescription of antibiotics.

关键词： Acute Respiratory Infections Virus Children Central African Republic

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Risk Factors of Early Neonatal Deaths in Pediatric Teaching Hospital in Bangui, Central African Republic

引用

Open Journal of Pediatrics 2021年第4期11卷 840-853页

作者： Jean Chrysostome Gody Moyen Engoba Brice Olivier Bogning Mejiozem Lydie Verleine Danebera evodie pierrette kakouguere Marie Collette Nganda Bangue Carine Judith Kiteze Nguinzanemou Romuald Belly de Dieu Komangoya Kpembi Petula Waraka Dusie Lesly Ngoyoli Mbode Mireille Mande Djapou Ghislain Franck Houndjahoue George Moyen Centre Hospitalier Universitaire Pédiatrique de Bangui (CHUPB) Bangui République Centrafricaine Université Marien Ngouabi Brazzaville Congo Médecins avec l’Afrique CUAMM International NGO Padova Italie

Background: The neonatal mortality rate in the Central African Republic (CAR) is 42.3 per 1000 live births in 2017, indicating that CAR is with the highest number of newborn deaths. Objective: The objective is to clarify the risk factors of neonatal deaths in this area. Methodology: A case-control study with retrospective data collection. Targets were newborns >7 days, hospitalized and dead (cases), and newborns admitted after the respective case during the study period and discharged before the 7th day of life. This study was carried out between 2016 and 2018 in the neonatal unit of the “Complexe Hospitalier Universitaire Pédiatrique de Bangui” (CHUPB), the only national hospital for newborns care in the CAR. Results: We included 902 newborns, with 451 cases of early neonatal death and 451 controls. 4168 newborns were admitted to the neonatology unit with 621 early death cases;a lethality rate of 14.9%. Early neonatal deaths factors were: newborns with low birth weight (OR = 22.59;95% CI [15.93 - 32.04]; P 25 years (OR = 2.08;95% CI [1.58 - 2.73];P < 0.001);non-medical transport (O

关键词： Early Neonatal Mortality Risk Factors CHUPB CAR

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Epidemiological, Clinical and Etiological Aspects of Non-Traumatic Comas in Children at the Pediatric Teaching Hospital in Bangui

引用

Open Journal of Pediatrics 2022年第3期12卷 489-506页

作者： Olivier Brice Bogning Mejiozem Moyen Engoba evodie pierrette Bogning Kakounguere Jean Chrysostome Gody Centre Hospitalier Universitaire Pédiatrique de Bangui Bangui Central African Republic Université Marien Ngouabi Brazzaville Republic of the Congo Faculté des Sciences de la Santé de l’Université de Bangui Bangui Central African Republic

Background: Non-traumatic coma is the most common pediatric medical emergency. Its clinical diagnosis is easy. The difficulty lies in finding the etiology. Objective: To determine the prevalence and clinical profiles of non-traumatic Coma at the Centre Hospitalier Universitaire Pédiatrique de Bangui (CHUPB). Methodology: This was a descriptive and analytical cross-sectional study conducted between January 1 and June 31, 2021, at CHUPB. Children aged 1 month to 15 years, admitted to the emergency room with a Glasgow score less than or equal to 8 without any traumatism were included. The variables studied were sociodemographic, clinical and paraclinical. Data were entered and analyzed using SPSS 20.0 statistical software. The statistical test used was Pearson’s chi2, any p-value Results: Of 8551 children hospitalized during the study period, 370 were hospitalized for non-traumatic coma: 4.32%. They were divided into 57.5% (n = 213) boys and 42.44% (n = 157) girls, giving a sex ratio of 1.35. Their mean age was 35.95 ± 27.21 months. Children aged 1 to 24 months represented 54.59% (n = 202) of cases. The mean time to the consultation was 2.91 days ± 1.8. Fever 86.48% (n = 320) and convulsions 80% (n = 296) were the main reasons for consultation. Coma stages II - III and IV represented 52.44% (n = 194), 42.97% (n = 159) and 4.59% (n = 17) respectively. Neuromalaria (29.72%;n = 110), meningitis-meningoencephalitis-encephalitis (30%;n = 111), sepsis (19.72%;n = 73) and acidosis Coma (5.40%;n = 20) were the main etiologies. Conclusion: Non-traumatic coma is common at CHUPB. Infections were the main etiology, particularly cerebral malaria. The reduction of its frequency requires, among others, the strengthening of the national monitoring malaria program. The strengthening of the technical platform for a good etiological diagnosis constitutes the other axis of prevention.

关键词： Non-Traumatic Coma Child Epidemiological-Clinical Etiological CHUPB

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Morbidity, Mortality and the Impact of Climate on the Evolution of Acute Rotavirus Diarrhea in Children under 5 Years Old in Bangui

引用

Open Journal of Pediatrics 2022年第4期12卷 607-632页

作者： Olivier Brice Bogning Mejiozem Sylvère Tenehombi-Koyangbo Lonela Gouandjika Vodie pierrette kakouguere Emmanuel Nakoune Gody Jean Chrysostome Centre Hospitalier Universitaire Pédiatrique de Bangui Bangui Central African Republic Institut Pasteur de Bangui Bangui Central African Republic Faculté des Sciences de la Santé Université de Bangui Bangui Central African Republic

Background: Rotavirus is the most common pathogen of severe acute diarrhea in children under five years of age worldwide. Objective: The objective of this study was to determine the morbidity and mortality of rotavirus diarrhea while describing the seasonal kinetics of the infection according to climatic parameters in Bangui. Methodology: This was a descriptive and analytical cross-sectional study conducted from January 1, 2011 to December 31, 2020 in the Central African Republic (CHUPB). The health data were recorded and processed with the Access 2019 software, then analyzed with the STATA version 14 software. The climatic trends in the study area and its seasonal variations were highlighted by the monthly rainfall coefficient of Alfred Angot: Cm = 12 Pm/P. Results: Morbidity was 45.99% of cases. The 1 to 12 months old represented 93.81% of cases. The mean age of the children was 6.8 months, the sex ratio was 1.20. The symptomatic triad was diarrhea (100%), vomiting (90.20%) and fever (87.5%). Moderate dehydration was reported in 81.05% of cases. The main genotype combinations found were P[8]G1 in 34.02% (n = 115/338), P[6]G1 in 21.59% (n = 73/338) and P[6]G2 in 16.86% (n = 57/338). Case fatality was 11.45%. The risk of death was influenced by rural origin, severe dehydration, hypovolemic cloc and duration of hospitalization > 5 days. Low rainfall correlated with the highest rates of rotavirus diarrhea. Likewise, high temperature correlated with the highest number of cases of rotavirus diarrhea. Conclusion: Acute rotavirus diarrhea is an important morbidity and mortality issue in children under 5 years old in Bangui.

关键词： Diarrhea Rotavirus Children Climate Bangui

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Influence of Climate Variability on the Dynamics of Malaria Transmission among Children in Bangui, Health Challenges in Central African Republic

引用

Open Journal of Pediatrics 2022年第3期12卷 461-475页

作者： Bogning Mejiozem Brice Olivier Mbetimangue Péngas Eliezer Edwige Victoire Ngatimo Bogning Kakounguere evodie pierrette Maurice Tsalefac Gody Jean Chrysostome Centre Hospitalier Universitaire Pédiatrique de Bangui Bangui Central African Republic Université de Dschang Dschang Cameroon Faculté des Sciences de la Santé de l’Université de Bangui Bangui Central African Republic

Background: Malaria was the deadliest worldwide vector-borne disease in 2017. The objective of this study was to determine the eco-epidemiology of malaria at the reduced scale of a Health Region in children less than 5 years old. Objectives: To assess the relationship between climate and malaria epidemiology in children less than 5 years old in Bangui. Methodology: Health data were collected from the Health Region Nº7 database. Climatic data were collected from the database of the Bangui M’poko station and the Bangui national meteorological delegation. Demographic data were collected from the United Nations Population Fund and the Central African Institute of Statistics, Economic and Social Studies. Ethical clearance was obtained from the local ethics committee, which allowed us to access the data from each institution. The independent variables were collected in the districts. Several statistical methods were used to analyze confidentially the data. Results: During the survey, for 1160 mm of water in 2004, 317 children died versus 56 for 1516 mm of water in 2013, i.e., a correlation coefficient between rainfall and malaria is 0.51. There was a statistically significant association between rainfall and malaria in Bangui as well as a correlation between malaria-related death and the level of humidity, i.e., for 51.99ºC, the number of death increased from 294 cases in 2004 to 216 cases for 49.74ºC in 2013 with a correlation coefficient between humidity and malaria morbidity of 0.46 and the coefficient of determination r2 of 21.31%. Malaria was influenced by humidity. Malaria transmission was higher during the rainy season (May to October) with an incidence of 61.11% (n = 44,193) versus 38.89% (n = 28,125) for the dry season (November to April). The 8th borough of Bangui with a very high level of vulnerability recorded the highest incidence of malaria (64,748 cases). Finally, the first borough with 11,502 cases of malaria had a very low level

关键词： Influence Climate Variability Malaria Children Bangui

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neonatal Tetanus at Pediatric Teaching Hospital in Bangui

引用

Open Journal of Pediatrics 2021年第2期11卷 179-188页

作者： Jean Chrysostome Gody Marie Christine Awa Sepou Yanza Olivier Brice Bogning Mejiozem Victoire NGatimo Franck Houndjahoué Vanessa Iris Gaspiet Sonny evodie pierrette Kakounguere Baptistine Anguize Aymard Trésor Guénefio Aristide Prince Mbeko Moyen Engoba Georges Moyen Centre Hospitalier Universitaire Pédiatrique de Bangui Bangui Central African Republic Faculté des Sciences de la Santé de l’Université de Bangui Bangui Central African Republic Université Marien Ngouabi Brazzaville Republic of Congo

Background: Despite the Maternal and Neonatal Tetanus (MNT) elimination initiative, neonatal tetanus still persists in some parts of the world. Objectives: To determine hospital prevalence and describe epidemiological, clinical, therapeutic and outcome aspects of neonatal tetanus at the Pediatric Teaching Hospital in Bangui. Methodology: It was the review of hospitalized newborns’ files in the neonatal unit at Pediatric Teaching Hospital in Bangui between January 2016 and December 2019. Newborns discharged with tetanus diagnosis, and whose files were usable were included. The variables studied were: for the newborn: age, sex, birth weight, the reason for transfer, diagnosis, cause and time of death, place and method of delivery;for the mother: age, antenatal care, tetanus vaccine status, parity and geographical provenance. Epi Info 7 software, version 7.***.3.3 was used for data analysis. The chi2 test with the significance level set at p Résultats: Forty-eight (48) out of 5796 newborns had neonatal tetanus (0.8%). They were newborns to mothers with an average age of 18.8 years of which 68.8% (n = 33) were primipara and 87.5% (n = 42) not vaccinated against tetanus. Childbirth happened at home in 91.7% (n = 44), and the blade was used for sectioning the umbilical cord in 39.6% (n = 19). Newborns were referred from rural area in 47.9% (n = 23). A single antenatal care contact was done in 68.7% (n = 33). Tetanus was classified as severe according to the Dakar prognosis score between 4 and 6 in 89.6% of cases (n = 43). The death occurred in 58.3%

关键词： Neonatal Tetanus Childbirth Mortality Bangui

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：