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Polychlorinated biphenyls (PCBs), hexabromocyclododecanes (HBCDDs) and degradation products in topsoil from Australia and the United Kingdom

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Emerging Contaminants 2016年第1期2卷 37-41页

作者： Jennifer Desborough Timothy evans Jochen Müller Stuart Harrad School of Geography Earthand Environmental SciencesUniversity of BirminghamBirmingham B152TTUnited Kingdom National Research Centre for Environmental Toxicology(Entox) The University of Queensland39 Kessels RoadBrisbaneQueensland 4108Australia

Hexabromocyclododecane(HBCDD)is listed under the Stockholm Convention on persistent organic pollutants,yet very few data are available on HBCDD concentrations in *** concentrations of total hexabromocyclododecanes(SHBCDDs)from soils from the UK(n=24)were 0.73 ng g^-1 dry weight(rangeng g^-1)and exceed significantly(p=0.002)those in Australian soils(n=17,median=0.10 ng g^-1,rangeng g^-1).Concentrations of polychlorinated biphenyls(PCBs)(average=4.7 ng SPCBs g^-1,range=0.39-21 ng g^-1)were determined in 19 UK samples and found to be statistically indistinguishable(p>0.05)from those of HBCDDs;thereby underlining the extent to which HBCDDs have migrated into the UK ***,PCB concentrations in this study are not markedly lower than those recorded in UK soils sampled in the mid-1980s indicating that the initial rapid decline in UK contamination with PCBs following bans on their manufacture and use,has not been *** products of HBCDD:pentabromocyclododecenes(PBCDs)and tetrabromocyclododecadienes(TBCDs)were detected in some UK soil samples with semi-quantitative concentrations ranging between 0.01 and 7.3 ng g^-1 for SPBCDs and 0.01e1.3 ng g^-1 for *** Australian soils only STBCDs were detected at concentrations ranging from 0.0023 to 0.45 ng g^-*** signatures of HBCDDs were racemic or non-racemic in all samples indicating minimal edaphic enantioselective degradation.A horizontal transect at the most contaminated UK location(a suburban garden)revealed a marked decrease in concentrations of HBCDDs with increasing distance from buildings.

关键词： Soil BFRs POPs Chiral signatures Enantiomer fractions

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网页设计四合一宝典 4

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丛书名：美国计算机“宝典”丛书

2004年

作者：（美）Joyce J.evans 盖江南等译

本书以一个贯穿全书的实例形式，介绍Macromedia MX 的四大软件，讲解制作网页和网站的整个工作流程的每一个具体步骤。

ISBN: (纸本)7121001241

本书以一个贯穿全书的实例形式，介绍Macromedia MX 的四大软件，讲解制作网页和网站的整个工作流程的每一个具体步骤。

关键词：制作网页软件工具

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Patterns and Presentation of Prostate Cancer in the Brong Ahafo Region of Ghana: A 6-Year Single Center Retrospective Study

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Health 2019年第4期11卷 351-360页

作者： Alexander Kofi Egote Paul Poku Sampene Ossei Eric Agyeman-Duah John Taylor evans Quarshie Department of Surgery (Urology Unit) Brong Ahafo Regional Hospital Sunyani Ghana Department of Pathology School of Medical Sciences KNUST/Komfo Anokye Teaching Hospital Kumasi Ghana

Introduction: Prostate cancer is gradually reaching a very high incidence in Africa, especially in the Sub-saharan region. Understanding the dynamics in occurrence of the disorder is one approach to developing effective public health programmes and interventions that will help curb the rising incidence. Objective: This study was aimed at reducing the paucity of data on prostate cancer by assessing the incidence, patterns and presentation in the Brong Ahafo Region of Ghana. We sought to provide region-specific hardcore data that will help to assess the issue and provide remedies. Method and Materials: All prostate disease cases recorded from the year 2009 to 2014 were retrospectively reviewed. Subjects from 40 years (based on previous studies) and above were eligible for screening. Diagnostic and screening tools for prostate cancer at the study site were family history, serum prostate specific antigen (PSA) test, digital rectal examination, urological ultrasound scan and histopathology (biopsy). Age, PSA values and year of screening/diagnosis were also retrieved from patient folders/archives for the purposes of the study. Histological findings and parameters considered in the study included diagnosis, carcinoma grading, perineural invasion (PNI) and percentage of affected tissues (%TA). Results: Prostate cancer constituted 236 cases (40.07%) of the 589 prostate diseases reviewed. The highest annual prevalence was recorded in 2014 with an incidence rate of 21.6% (51 cases). The ages of patients ranged from 46 to 101 years with a modal age range of 70 - 79 years and a mean ± SD of 71.7 ± 11.2. The mean PSA value recorded was 37.5 ng/ml (±68.9) with predominance in the 11 - 20.9 ng/ml (61 cases/patients) (27.9%) range. Moderately differentiated adenocarcinoma was the dominant grade of prostate cancer accounting for 61.4% (145 cases) of the 236 cases. There was a significant correlation (p = 0.001) between grading of prostate cancer and perineural invasion. Only 21.2% gr

关键词： Prevalence Prostate Cancer Serum PSA Brong Ahafo Region Ghana

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Trifecta Outcomes of Screening Detected and Patients with Lower Urinary Tract Symptoms after Open Radical Prostatectomy for Localized Prostate Cancer

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Open Journal of Urology 2023年第8期13卷 282-292页

作者： Mathew Yamoah Kyei James Edward Mensah Robert Djagbletey evans Akpali Francis Ahiaku Ali Ayamba Ben Adusei Enoch Tackie Emmanuel Bannerman-Williams George Oko Klufio Department of Surgery University of Ghana Medical School Accra Ghana Department of Anaesthesia University of Ghana Medical School Accra Ghana Department of Surgery Korle Bu Teaching Hospital Accra Ghana The Trust Hospital Accra Ghana University of Health and Allied Science Ho Ghana 37 Military Hospital Accra Ghana

Background: Many studies have reported on trifecta outcomes after radical prostatectomy. There is however paucity of studies that compares the trifecta outcome between screen detected and patients presenting with lower urinary symptoms with localized prostate cancer after radical prostatectomy. This study compares the trifecta outcomes between these two groups after an open retropubic radical prostatectomy. Methodology: This is a retrospective study, on the trifecta outcomes (urinary continence, erectile function, and cancer control) of consecutive patients that had open radical retropubic prostatectomy for localized prostate cancer by a single surgeon. Patients were grouped into screen detected and presentation with lower urinary symptoms or retention of urine. The parameters considered were the age of the patients, the total prostate specific antigen (tPSA) at presentation, the clinical T stage, the Gleason score of prostate biopsies, the risk categories using the D’Amico risk groups and the trifecta outcomes after the procedure. Results: In all, 119 patients met the criteria for inclusion. The median follow up was 63.5 months (range 12 - 156 months). Of these 40.3% of the patients were diagnosed through screening with elevated PSA while 59.7% had presented with symptoms of lower urinary tract obstruction. The mean age for the patients was 60.8 ± 6.5 years, median PSA 12.6 ng/ml (IQR 8.6 - 19.7) and median prostate weight of 50.0 (IQR 40.0 - 60 g). The urinary continence rate after the procedure was 93.3%, erection rate of 81.5%, cancer control rate of 71.4% and trifecta achieved in 57.1%. Comparing the screening and the symptomatic cases, the urinary continence rate was 91.7% vrs 94.3%;erectile function rate was 79.2% vrs 83.1%;cancer control 68.8% vrs 73.2% and trifecta achieved in 58.3% vrs 56.3%. There was no statistically significant difference between the two groups in terms of urinary continence p = 0.564, erection function p = 0.588, cancer control p = 0.5

关键词： Screening Lower Urinary Tract Symptoms Open Radical Prostatectomy Functional Outcome Trifecta

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澳大利亚对残疾学生教育经费投入的改革及启示

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残疾人研究 2019年第1期 32-39页

作者：汪斯斯大卫.埃文斯南京特殊教育师范学院特殊教育研究中心南京210038 澳大利亚悉尼大学教育与社会工作学院

近年来,澳大利亚联邦政府主要通过"优质学校项目"和"全国残疾人保障计划"两项举措,对残疾学生的教育经费投入进行改革。"优质学校项目"是中小学校的经费改革项目,从个体需求出发,主要在于教育投入经费的稳健增长以及重视经费的监管。"... 详细信息

近年来,澳大利亚联邦政府主要通过"优质学校项目"和"全国残疾人保障计划"两项举措,对残疾学生的教育经费投入进行改革。"优质学校项目"是中小学校的经费改革项目,从个体需求出发,主要在于教育投入经费的稳健增长以及重视经费的监管。"全国残疾人保障计划"是对残疾人的长期资助项目,关注按需选择资助服务、与学校合作资助学生、提供长期教育资助和资助残疾人的家人及生活照料者。总结这两个项目中对残疾学生教育经费投入的改革举措,发现它们均存在融合性、个别化、循证性和协作性的特点,这为完善我国残疾学生的教育经费投入体制提供了启示。

关键词：澳大利亚残疾学生教育经费投入按需资助循证实践

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HIV感染妇女宫颈上皮内瘤样I级病变的自然病程

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世界核心医学期刊文摘（妇产科学分册） 2005年第9期1卷 53-54页

作者： Massad L.S. evans C.T. Minkoff H. 张巧利 Department of Obste trics Southern Illinois University PO Box 19640 Springfield IL 62794-9640 United States Dr.

OBJECTIVE: We sought to estimate rates of progression and regression of grad e 1 cervical intraepithelial neoplasia (CIN 1) among women with human immunodefici ency virus (HIV). METHODS: In a multicenter prospective cohort study, HIV-serop ositive and HIV-seronegative women were evaluated colposcopically after receivi ng an abnormal cytology test result between November 1994 and September 2002. Wo men with CIN 1 were included, except those who had undergone hysterectomy, cervi cal therapy, or had CIN 2-3 or cervical cancer. Those women who were included w ere followed cytologically twice yearly, with colposcopy repeated for atypia or worse. RESULTS: We followed 223 women with CIN 1 (202 HIV seropositive and 21 HI V seronegative) for a mean of 3.3 person-years. Progression occurred in 8 HIV- seropositive women (incidence density, 1.2/100 person-years; 95%confidence int erval [CI] 0.5-2.4/100 person-years) and in no HIV seronegative women. Regress ion occurred in 66 (33%) HIV-seropositive women (13/100 person-years, 95%CI 10-16/100 person-years) versus 14 (67%) seronegative women (32/100 person-ye ars, relative risk 0.40, 95%CI 0.25-0.66; P < .001). In multivariate analysis, regression was associated with human papillomavirus ( HPV) detection (hazard ratio [HR] for low risk 0.28, 95%CI 0.13-0.61, P=.001; and for high-risk 0.34,95%CI 0.20-0.55, P < .001 versus no HPV detected) and Hispanic ethnicity (HR 0.48, 95%CI 0.23-0.98; P = .04); HIV serostatus was onl y marginally linked to regression (HR 0.52, 95%CI 0.27-1.03; P=.06), but serop ositive women were less likely to regress when analysis was limited to 146 women with HPV detected at CIN 1 diagnosis (HR 0.18, 95%CI 0.05-0.62; P = .006). CO NCLUSION: Grade 1 cervical intraepithelial neoplasia infrequently progresses in women with HIV. Thus, observation appears safe absent oilier indications for tre atment.

关键词：上皮内瘤 HIV感染不典型增生阴道镜检查血清阳性子宫切除转归情况前瞻性队列研究多元分析

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E-钙黏蛋白表达对乳腺摄影筛查中侵袭性非小叶性乳腺癌的影像征象的影响

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国际医学放射学杂志 2009年第6期 581-582页

作者： S.Doyle A.J.evans E.A.Rakha A.R.Green I.O.Ellis 庄晓曌 Nottingham Breast Institute Nottingham City Hospital National Health Service TrustUniversity of NottinghamHucknall RoadNG5 1PB NottinghamEngland

目的比较乳腺非小叶癌(nonlobular cancers,NLCsE-钙黏蛋白表达丢失者与表达正常者的乳腺摄影片上影像表现的差别。材料与方法本研究获得医院伦理委员会批准,无需签署知情同意书。某前瞻性乳腺癌筛查项目的数据库中共录入1944例年龄小... 详细信息

目的比较乳腺非小叶癌(nonlobular cancers,NLCsE-钙黏蛋白表达丢失者与表达正常者的乳腺摄影片上影像表现的差别。材料与方法本研究获得医院伦理委员会批准,无需签署知情同意书。某前瞻性乳腺癌筛查项目的数据库中共录入1944例年龄小于70岁

关键词：钙黏蛋白乳腺摄影乳腺癌乳腺肿瘤侵袭性

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A monolithic single-chip point-of-care platform for metabolomic prostate cancer detection

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Microsystems & Nanoengineering 2021年第2期7卷 81-95页

作者： Valerio F.Annese Samadhan B.Patil Chunxiao Hu Christos Giagkoulovits Mohammed A.Al-Rawhani James Grant Martin Macleod David J.Clayton Liam M.Heaney Ronan Daly Claudio Accarino Yash D.Shah Boon C.Cheah James Beeley Thomas R.Jeffry evans Robert Jones Michael P.Barrett David R.S.Cumming Electronics and Nanoscale Engineering James Watt School of EngineeringUniversity of GlasgowGlasgowG128QQUK Beatson West of Scotland Cancer Centre GlasgowG120YNUK School of Science and Technology Nottingham Trent UniversityNottinghamNG118NFUK School of Sport Exercise&Health SciencesLoughborough UniversityLoughboroughLE113TUUK Glasgow Polyomics College of MedicalVeterinary and Life SciencesUniversity of GlasgowGlasgowG611BDUK Institute of Cancer Sciences Beatson West of Scotland Cancer CentreUniversity of GlasgowGlasgowG120YNUK Institute of Infection Immunity and InflammationUniversity of GlasgowGlasgowG128TAUK

There is a global unmet need for rapid and cost-effective prognostic and diagnostic tools that can be used at the bedside or in the doctor’s office to reduce the impact of serious *** cancers are diagnosed late,leading to costly treatment and reduced life *** prostate cancer,the absence of a reliable test has inhibited the adoption of screening *** report a microelectronic point-of-care metabolite biomarker measurement platform and use it for prostate cancer *** platform,using an array of photodetectors configured to operate with targeted,multiplexed,colorimetric assays confined in monolithically integrated passive microfluidic channels,completes a combined assay of 4 metabolites in a drop of human plasma in under 2 min.A preliminary clinical study using L-amino acids,glutamate,choline,and sarcosine was used to train a cross-validated random forest *** system demonstrated sensitivity to prostate cancer of 94%with a specificity of 70%and an area under the curve of *** technology can implement many similar assay panels and hence has the potential to revolutionize low-cost,rapid,point-of-care testing.

关键词： inhibited specificity hence

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老年人股骨粗隆间骨折的治疗选择

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中国骨伤 2012年第1期28卷 35-38页

作者：康维杰夏晨波邓勇军张居适绍兴文理学院附属医院骨科浙江绍兴312000

目的:探讨老年人股骨粗隆间骨折的治疗选择。方法:2006年6月至2010年6月手术治疗老年人股骨粗隆间骨折58例,男25例,女33例;年龄65～93岁,平均79岁。按evans分型:Ⅰ型30例,Ⅱ型28例。58例中25例采用关节置换治疗(A组),33例采用内固定治... 详细信息

目的:探讨老年人股骨粗隆间骨折的治疗选择。方法:2006年6月至2010年6月手术治疗老年人股骨粗隆间骨折58例,男25例,女33例;年龄65～93岁,平均79岁。按evans分型:Ⅰ型30例,Ⅱ型28例。58例中25例采用关节置换治疗(A组),33例采用内固定治疗(B组)。对两组的手术时间、术中出血量、术后下床活动时间、引流量、并发症及关节活动功能进行比较,其中关节活动功能采用Harris评分分别在术后3,6,12个月进行评定。结果:所有病例均获得1年以上随访,A组1例患者术后1个月并发肺炎死亡,其余患者均安全度过围手术期。B组在手术时间、术中出血量、引流量方面均优于A组。并发症:A组死亡1例,深静脉血栓1例,尿路感染2例,肺炎1例;B组发生褥疮1例,髋内翻1例,尿路感染2例。B组并发症发生率比A组低(χ2=10.1648,P0.05)。术后3个月:A组优14例,良5例,中5例,差1例;B组优8例,良13例,中9例,差3例。术后6个月:A组优18例,良5例,中2例,差0例;B组优10例,良15例,中6例,差2例。术后12个月:A组优18例,良5例,中1例,差1例;B组优21例,良9例,中3例,差0例。术后3、6个月,A组的疗效优于B组(P0.05)。结论:老年人股骨粗隆间骨折应首先选择内固定治疗,关节置换主要适用于肿瘤引起的病理性骨折、被忽视的骨折畸形以及股骨干骨质差无法采用或尝试内固定治疗的患者、或同侧症状性退行性关节病的患者、内固定失败的翻修以及粗隆间粉碎骨折比较重且合并严重骨质疏松者。

关键词：股骨粗隆间骨折骨折固定术,内关节成形术,置换,髋老年人病例对照研究

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侵袭性乳腺癌超声与新的分子分类的相关性

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国际医学放射学杂志 2009年第6期 601-601页

作者： I.T.Au-Yong A.J.evans S.Taneja E.A.Rakha A.R.Green C.Paish 蒋新华 Nottingham Breast Institute City HospitalHucknall RoadNottinghamUKNG5 1PB

对于乳腺实质性病变的定性和活检,超声是钼靶查的重要补充。乳腺癌的蛋白表达分析已经确定具有潜在床、生物以及治疗价值的亚型分组。本研究的目的是确定袭性乳腺癌超声表现与这些新的新型分子分类的相关性。58例可手术的乳腺癌病人的... 详细信息

对于乳腺实质性病变的定性和活检,超声是钼靶查的重要补充。乳腺癌的蛋白表达分析已经确定具有潜在床、生物以及治疗价值的亚型分组。本研究的目的是确定袭性乳腺癌超声表现与这些新的新型分子分类的相关性。58例可手术的乳腺癌病人的超声结

关键词：乳腺癌蛋白表达乳腺肿瘤分子分类侵袭性相关性超声

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