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Characteristics an. outcomes of hepatocellular carcin.ma patien.s with macrovascular in.asion.followin. surgical resection. a meta-an.lysis of 40 studies an. 8,218 patien.s

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Hepatobiliary Surgery an. n.trition 2022年第6期11卷 848-860,I0001-I0015页

作者： Dan.el Q.Huan. An.rew Tran.eunice XTan.San.n. n.n.rurkar Readon.Teh Margaret L.P.Ten. Ee Jin.Yeo Biyao Zou Con.ie Won. Carlos O.Esquivel CAn.rew Bon.am Min.ie H.n.uyen Division.of Gastroen.erology an. Hepatology Department of MedicineNational University HospitalSingaporeSingapore Departmen. of Medicin. Yong Loo Lin School of MedicineNational University of SingaporeSingaporeSingapore Duke Un.versity DurhamNCUSA Adelaide Medical School The University of AdelaideAdelaideAustralia Division.of Gastroen.erology an. Hepatology Department of MedicineStanford University Medical CenterPalo AltoCAUSA Departmen. of Epidemiology an. Population.Health Stanford University School of MedicineStanfordCAUSA Lan. Medical Library Stanford University School of MedicineStanfordCAUSA Division.of Abdomin.l Tran.plan.ation Department of SurgeryStanford University School of MedicineStanfordCAUSA

Backgroun.:Guidelin.s recommen. that hepatocellular carcin.ma(HCC)patien.s with portal vein.tumor thrombosis(PVTT)an./or hepatic vein.tumor thrombosis(HVTT)should un.ergo systemic ***,recen. data suggest that surgical resection.may be ben.ficial in.selected cases,but outcomes are *** aimed to estimate pooled overall survival(OS),recurren.e free survival(RFS)an. complication.rates in.HCC patien.s with macrovascular in.asion.MVI)followin. surgical ***:In.this systematic review an. meta-an.lysis,two in.estigators in.epen.en.ly searched PubMed,Embase,an. Cochran. databases from in.eption.to n.v 10,2020,without lan.uage restriction.,for studies reportin. outcomes of adult HCC patien.s with MVI who un.erwen. liver resection.with curative ***:We screen.d 8,598 articles an. in.luded 40 studies in.olvin. 8,218 *** all patien.s with MVI,the pooled median.OS was 14.39 mon.hs[95%con.iden.e in.erval(CI):10.99-18.84],1-year OS was 54.47%(95%CI:46.12-62.58%)an. 3-year OS was 23.20%(95%CI:16.61-31.42%).Overall,1-an. 3-year RFS were 27.70%(95%CI:21.00-35.57%)an. 10.06%(95%CI:6.62-15.01%),*** patien.s with PVTT,median.OS was 20.41 mon.hs in.those with segmen.al/2n. order in.olvemen. compared to 12.91 mon.hs if 1st order bran.h was in.olved an. 6.41 mon.hs if the main.trun. was *** pooled rate of major complication. was 6.17%(95%CI:3.53-10.56%).Con.lusion.:Overall median.survival was 14.39 mon.hs for HCC patien.s with MVI followin. *** survival was higher in.PVTT with segmen.al/2n. order in.olvemen. at 20.41 versus 6.41 mon.hs if the main.trun. was in.olved.

关键词： Hepatocellular carcin.ma(HCC) resection portal vein macrovascular in.asion.MVI) recurren.e

Global lon.itudin.l strain.is superior to ejection.fraction.for detectin. myocardial dysfun.tion.in.en.-stage ren.l disease with hyperparathyroidism

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World Journ.l of Cardiology 2022年第4期14卷 239-249页

作者： Maria Fern.n.a Carrasco-Ruiz An.on.o Ruiz-Rivera Marvin.A Sorian.-Ursúa Carlos Martin.z-Hern.n.ez Leticia Man.el-Apolin.r Carmen.Castillo-Hern.n.ez Gustavo Guevara-Balcazar eunice D Farfán.García An. Mejia-Ruiz Ivan.Rubio-Gayosso Teresa Perez-Capistran Departmen. of Physiology Escuela Superior de MedicinaInstituto Politécnico NacionalCiudad de México 11340Mexico Departmen. of Cardiology Instituto Mexicano del Seguro SocialCiudad de México 06720Mexico En.ocrin. Research Un.t Instituto Mexicano del Seguro SocialCiudad de México 06720Mexico Departmen. of Cardiovascular Pharmacology Instituto Politécnico NacionalCiudad de México 11340Mexico Departmen. of Biochemistry Escuela Superior de MedicinaInstituto Politécnico NacionalCiudad de México 11340Mexico Education.Research Comisión Nacional Para la Mejora Continua de la EducaciónCiudad de México 03900Mexico Postgraduate Studies an. Research Section Escuela Superior de MedicinaInstituto Politécnico NacionalCiudad de México 11340Mexico Departmen. of Physiology Instituto Politécnico NacionalMexico City 11340Ciudad de MéxicoMexico

BACKGROUn. The estimation.of left ven.ricular ejection.fraction.LVEF)by 2D echocardiography(2D-ECHO)is the most used tool to assess LV systolic fun.tion.LVSF).Global lon.itudin.l strain.GLS)has recen.ly been.suggested as a superior method for several *** study explored the association.an. prevalen.e of LV systolic dysfun.tion.LVSD)by usin. these methods in.patien.s with en.-stage ren.l disease(ESRD)an. severe hyperparathyroidism(SHPTH);both associated with cardiovascular even.s(CEs).AIM To evaluate the myocardial fun.tion.in.patien.s with ESRD an. SHPTH by usin. the GLS an. LVEF measured through con.en.ion.l *** In.62 patien.s with ESRD an. SHPTH,asymptomatic,an. without a history of CEs,LVSF was evaluated by 2D-ECHO,obtain.n. the EF,by the Simpson.biplan. method,an. GLS by speckle *** The total patien.s with ESRD had a preserved LVEF(>50%)but abn.rmal GLS(n.lly,multivariate an.lysis showed an.in.epen.en. association.of GLS an. serum parathyroid hormon.(PTH),LV mass in.ex,an. ***,PTH was in.epen.en.ly associated with lateral e'wave an. tricuspid regurgitation.*** In.patien.s with SHPTH lin.ed to ESRD,the use of GLS by 2D-ECHO is a more sen.itive tool than.LVEF for detectin. LVSD.

关键词： Left ven.ricular hypertrophy Systolic dysfun.tion Global lon.itudin.l strain En.-stage ren.l disease Parathormon.

In.ibition.of <i>Magn.porthe oryzae</i>by Culture Filtrates of Fun.i Isolated from Wild Mushrooms

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Advan.es in.Microbiology 2015年第10期5卷 686-692页

作者： Quyet n.uyen.Thi Kan. Ueda Jun.chi kihara Makoto Uen. Faculty of Life an. En.iron.en.al Scien.e Shimane University Matsue Japan

Fun.al strain. isolated from the fruitin. bodies of wild mushrooms were evaluated for fun.icidal activity again.t Magn.porthe oryzae, the causal agen. of the rice blast disease. Fun.al isolates (n.= 105) were obtain.d from 46 samples of wild mushrooms. In.ection.behaviors of M. oryzae were assessed in.the presen.e of culture filtrates from 90 fun.al isolates, of which 20 in.ibited spore germin.tion. Heat-treated culture filtrates of these isolates were classified in.o 3 groups accordin. to biological activity. Blast lesion.formation.by M. oryzae was sign.fican.ly in.ibited by pretreatmen. with culture filtrates from 4 fun.al isolates. ITS region.sequen.e an.lysis in.icated that these?isolates shared similarities with species of the gen.ra An.ulohypoxylon. n.grospora, an. Pen.cillium. Studies of symbiotic an. parasitic fun.i from wild mushrooms may yield poten.ial con.rol agen.s for plan. diseases such as the rice blast disease.

关键词： Rice Blast Disease Culture Filtrate An.ifun.al Compoun. Magn.porthe oryzae Mushroom

Evaluation.of coron.ry microvascular fun.tion.in.patien.s with vasospastic an.in.

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World Journ.l of Cardiology 2013年第1期5卷 1-7页

作者： Hiroki Teragawa n.oya Mitsuba Ken.Ishibashi Ken.i n.shioka Satoshi Kurisu Yasuki kihara Departmen. of Cardiovascular Medicin. Hiroshima General Hospital of West Japan Railway Company Hiroshima 732-0057 Japan Departmen. of Cardiovascular Medicin. Hiroshima University Graduate School of Biomedical Sciences Hiroshima 734-8551 Japan

AIM: To in.estigate en.othelium-depen.en. an. in.epen.en. coron.ry microvascular fun.tion. in.patien.s with vasospastic an.in. (VSA). METHODS: Thirty-six patien.s with VSA (30 men.an. 6 women. mean.age, 58 years) were en.olled in.this study. VSA was defin.d as ≥ 90% n.rrowin. of the epicardial coron.ry arteries on.an.iography performed durin. a spasm provocation.test, presen.e of chest pain. an./or ST-segmen. deviation.on.an.electrocardiogram (ECG). Patien.s (n.= 36) with n.gative spasm provocation.test results an. those matched for age an. sex were en.olled as a con.rol group (n.n.SA group). Low-dose acetylcholin. (ACh; 3 μg/min. was in.used in.o the left coron.ry ostium for 2 min.durin. the spasm provocation.test. Followin. the spasm provocation.test, n.troglycerin.(0.2 mg) was admin.stered in.racoron.lly. Coron.ry blood flow (was calculated from quan.itativean.iography an. Doppler flow velocity measuremen.s, an. the coron.ry flow reserve was calculated as the ratio of coron.ry flow velocity after in.ection.of aden.sin. triphosphate (20 μg) to the baselin. value. Chan.es in.the coron.ry artery diameter in.respon.e to ACh an. n.troglycerin.in.usion.were expressed as percen.age chan.es from baselin. measuremen.s. RESULTS: Body mass in.ex was sign.fican.ly lower in.the VSA group than.in.the n.n.SA group. The fre- quen.y of con.en.ion.l coron.ry risk factors an. the rate of statin.use were similar between.the 2 groups. The left ven.ricular ejection.fraction.as evaluated by echocardiography was similar between.the 2 groups. The duration.of an.in. was 9 ± 2 mo. The results of blood chemistry an.lysis were similar between.the 2 groups. Low-dose ACh did n.t cause coron.ry spasms. The chan.e in.coron.ry artery diameter in.respon.e to ACh was lower in.the VSA group (-1.4% ± 9.3%) than.in.the n.n.SA group (3.1% ± 6.5%, P n.troglycerin.in.uced coron.ry artery dilatation.an. coron.ry blood flow in.rease in.respon.e to ACh or coron.ry flow reserve did n.t di

关键词： Coron.ry spasm En.othelial fun.tion Acetylcholin.

Tillage, <i>Desmodium in.ortum</i>, Fertilizer Rates for Carbon.Stock, Soil Quality an. Grain.Yield in.n.rthern.Guin.a Savan.a of n.geria

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American.Journ.l of Climate Chan.e 2019年第2期8卷 325-341页

作者： Odun.e Azubuike Chidowe Asholo David Blessin. Ogun.ole Joshua Olalekan.Oyin.ola eunice Yetun.e Chin.e n.echi Mary Departmen. of Soil Scien.e/In.titute for Agricultural Research Ahmadu Bello University Zaria Nigeria BOWEn.Un.versity Iwo Ado Ekiti State Nigeria

n.rthern.Guin.a Savan.a of n.geria soils are con.in.ously an. in.en.ively cultivated, resultin. in.soil quality degradation. carbon.stock depletion. accelerated soil erosion.an. soil n.trien. depletion. Effects of lan. use chan.e on.soil carbon.stocks (SOC) are of con.ern.regardin. green.ouse gas emission. mitigation.an. sustain.ble crop production. because there is a n.ed for food sufficien.y while con.ervin. the en.iron.en.. Also, man.gin. soils un.er in.en.ive use an. restorin. degraded soils are top priorities for a sustain.d agron.mic production.while con.ervin. soil an. water resources. Hen.e, this study;“Tillage, Desmodium in.ortum, fertilizer rates for carbon.stock, soil quality an. grain.yield in.n.rthern.Guin.a Savan.a” is aimed at devisin. possible mitigatin. measures for soil quality degradation. carbon.stock depletion.an. impoverished crop yields usin. Zea mays as test crop. The study was a Ran.omized Complete Block Design.(RCBD) in.split-split plot arran.emen. with four replicates. The four main.tillage an. Desmodium in.ortum combin.tion.treatmen.s were: 1) Maize −without Desmodium + Con.en.ion.l tillage (MC), 2) Maize + Desmodium live-mulch in.orporated an. relayed + Con.ervation.tillage (MDIC), 3) Maize + Desmodium in.n.-tillage system (MDn.), 4) Maize + Desmodium in.strip tillage (MDST). The main.treatmen. plots were each divided to accommodate four (4) rates of n.(60, 80, 100 an. 120 kg·ha−1) as sub plots, while the n.rate plots were further divided to accommodate three (3) rates of P (6.6, 13.2, an. 26.4 kg·ha−1) as sub-subplots. Fin.in.s support that Desmodium in.ercrops with Maize treatmen.s (MDIC, MDn., an. MDST) resulted in.in.reased organ.c carbon.con.en.s in.2013, with MDn. resultin. in.sign.fican.ly higher organ.c carbon.con.en. (7.37 g·kg−1 in.2012 an. 8.37 g·kg−1 in.2013) than.the other treatmen.s. Also, zero tillage practice (MDn.) sequestered sign.fican.ly higher carbon.stock (18.06 t C ha−1), followe

关键词： Carbon Stock Tillage Soil Quality Grain Yield Climate Chan.e Mitigation

Effects of primovaccin.tion.an. booster vaccin.tion.on.serum cortisol an. humoral immun. respon.e in.cattle

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Advan.es in.Bioscien.e an. Biotechn.logy 2013年第5期4卷 607-611页

作者： Luis S.L.S.Reis Paulo E.Pardo n.usa M.Frazatti-Gallin. Rosan. L.Paoli eunice Oba Sergio n.Kron.a Alin. S.Camargos Departmen. of Bromatology Food and Animal NutritionUniversidade de Santo AmaroSao PauloBrazil Departmen. of Medical Clin.c Universidade do Oeste PaulistaPresidente PrudenteBrazil Section.of Rabies of In.tituto Butan.an Sao PauloBrazil Departmen. of An.mal Reproduction.an. Veterin.ry Radiology Universidade Estadual PaulistaFaculdade de Medicina Veterinaria e ZootecniaCampus BotucatuBrazil Un.versidade Estadual Paulista Faculdade de Ciencias Agrarias e Veterinarias de JaboticabalCampus JaboticabalBrazil

The objective of this study was to evaluate the effect of on. or two doses of the an.i-rabies vaccin.tion.on.the serum con.en.ration.of cortisol an. the humoral immun. respon.e in.cattle as well as the correlation.between.serum cortisol con.en.ration. an. the titers of rabies-n.utralizin. an.ibodies. n.lore cattle were ran.omly assign.d to on. of three groups, which were vaccin.ted with on. dose of rabies vaccin. (group GVSR, n.= 15), two doses of rabies vaccin. (group GVR, n.= 15) or were n.t vaccin.ted (group Gc, n.= 15). A commercial liquid in.ctivated rabies vaccin. was used. The stressors imposed on.the cattle were vaccin.tion. corral han.lin. an. the presen.e of people. Blood samples were collected on.days 0, 30 an. 60 post-vaccin.tion. Serum cortisol con.en.ration. were determin.d usin. a solid-phase radioimmun.assay, an. rabies an.ibody titers were determin.d usin. a serum n.utralization.test with BHK21 cells (RFFIT). Both serum cortisol con.en.ration. an. an.ibody titers in.reased after the secon. (booster) vaccin.tion.(P n.all the groups, the serum cortisol con.en.ration. in.reased after the cattle were han.led in.the corral (P n. correlation.was observed between.the serum cortisol con.en.ration. an. the an.ibody titers with an. treatmen. or on.an. observation.day. In.con.lusion. booster vaccin.tion.is in.ispen.able for primovaccin.ted cattle in.achievin. high an. protective levels of rabies an.ibodies. Although booster vaccin.tion.an. frequen. cattle han.lin. in.corrals are stressors, the respon.e is n.t stron. en.ugh to cause immun.suppression.in.cattle.

关键词： Cattle Stress Stressor Cortisol Rabies Vaccin.tion An.ibody

由标准气象站数据估计出的非洲撒哈拉以南土壤的气候和分解者活动:土壤碳平衡计算的一个简单气候指数

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AMBIO－人类环境杂志 2007年第5期36卷 361-368页

作者： Olof An.rén.Job kihara An.ré Bation. Bern.rd Van.auwe Thomas Ktterer 王胜瑞典农业大学(SLU)土壤科学系热带农业国际中心热带土壤生物和肥力研究所 TSBF-CIAT 瑞典农业大学(SLU)

本文逐日计算了土壤的生物学活动,使用的是非洲气象站的标准气象数据、一个简单的土壤水分模型,并且使用了关于温度、土壤含水量和生物学活动之间关系的一般性假设。活动系数r_(e_clim)由日土壤湿度和温度计算得出,从而考虑了温度与湿... 详细信息

本文逐日计算了土壤的生物学活动,使用的是非洲气象站的标准气象数据、一个简单的土壤水分模型,并且使用了关于温度、土壤含水量和生物学活动之间关系的一般性假设。活动系数r_(e_clim)由日土壤湿度和温度计算得出,从而考虑了温度与湿度之间的交互作用。瑞典中部(粘壤土,无作物)r_(e_clim)的年均值标准化为1,在那里进行了最初的校准。由于土壤在储水能力和植物覆被上的差异会对蒸腾作用产生影响,所以我们选择的样地均为无作物的该土壤,这样就只包括了气候差异。瑞典r_(e_clim)值,1,相当于诸如表土中含有的谷类秸杆等的年质量亏损约50%。非洲r_(e_clim)年均值在干热地点(法亚,乍得)为1.1,温湿地点(布拉柴维尔,刚果)为4.7之间变动。肯尼亚样地的r_(e_clim)值为2.1(高海拔,Matan.a)至4.1(肯尼亚西部,Ahero)。这意味着假如土壤类型和经营相同,那么必须有4.1倍于瑞典的碳输入才能将Ahero的土壤碳水平维持在瑞典水平。对每一块样地都绘制了r_(e_clim)日动态图,并讨论了年内动态差异。模拟实验表明,如果将土壤碳平衡的瑞典土壤移至肯尼亚的Ahero,30年内其土壤碳将损失41%。如果将Ahero保持碳平衡的土壤移至瑞典,30年内其土壤碳含量将增加64%。本文讨论了方法与结论的有效性,并将r_(e_clim)与其它气候指数进行了对比。本文还提出了一种对r_(e_clim)值进行粗略估计的简易方法。

关键词：气候指数土壤碳平衡计算标准化气象站非洲估计分解者

氮肥运筹对陇中旱农区玉米光合特性及产量的影响

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草业学报 2019年第1期28卷 60-69页

作者：王进斌谢军红李玲玲 eunice Essel 彭正凯邓超超沈吉成颉健辉甘肃省干旱生境作物学重点实验室甘肃农业大学农学院甘肃兰州730070

全膜双垄沟播技术使玉米成为了陇中旱农区主要作物之一,但该技术下玉米的高产出导致土壤养分耗竭,影响玉米生产的可持续性。本研究依托2012年布设在陇中旱农区的田间定位试验,研究4个施氮水平(n.:不施肥;n.:100kg·hm^(-2)、n.:200kg·h... 详细信息

全膜双垄沟播技术使玉米成为了陇中旱农区主要作物之一,但该技术下玉米的高产出导致土壤养分耗竭,影响玉米生产的可持续性。本研究依托2012年布设在陇中旱农区的田间定位试验,研究4个施氮水平(n.:不施肥;n.:100kg·hm^(-2)、n.:200kg·hm^(-2)、n.:300kg·hm^(-2))和2个施氮时期(T1:1/3基肥+1/3拔节期+1/3开花期、T2:1/3基肥+2/3拔节期)对玉米光合特性、叶绿素含量、叶面积指数、干物质积累和分配量及产量的影响。结果表明:1)随着施氮量的增加玉米光合性能也在增强,而n.和T2n.间差异不显著,T2时期提高玉米光合特性;2)全生育期内,n.处理下叶绿素含量较n.、n.、n.分别平均增加50.9%、17.0%、2.7%;叶面积指数也随施氮量的增加而增加,但n.和n.间无显著差异;T2下的叶绿素含量和叶面积指数在生育后期显著高于T1;3)干物质积累量和籽粒分配量表现为:n.>n.>n.>n.,T2下的干物质积累和籽粒分配量高于T1;4)籽粒产量和生物产量均随施氮量的增加而增加,n.和n.下的籽粒产量和生物产量显著高于n.,其中n.较n.增加79.2%和68.4%,n.较n.增加65.9%和54.1%,T2下的籽粒产量和生物产量分别较T1显著增加9.9%和13.5%,而T2n.与n.间无显著差异,因此,在陇中旱农区应用全膜双垄沟播技术种植玉米,施纯氮200kg·hm^(-2)左右,按照1/3基肥+2/3拔节期配施,可以增强光合作用,从而提高玉米籽粒产量和饲料产量,促进玉米生产可持续发展。

关键词：施氮量施氮时期玉米光合特性产量

尼日利亚纳萨拉瓦州市售灌木芒果、腰果、秋葵、芝麻和高粱的真菌毒素污染情况研究

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粮油食品科技 2021年第6期29卷 71-82页

作者： Isaac M Ogara Michael Sulyok An.hon. n.gedu Kolawole I Ayen. Zega M Zebedee John.D Mamman.Abiodun.Adedokun.Jan.t I Ogara eunice A Adgidzi Chibun.u n.Ezekiel Rudolf Krska 纳萨拉瓦州立大学沙布拉菲亚校区农学院农学系PMB 335尼日利亚纳萨拉瓦州凯菲950101 维也纳自然资源与生命科学大学(BOKU) 生物分析与农业代谢组学研究所农业生物技术学院(IFA-Tulln)奥地利图尔恩20.3430 原材料研究与发展委员会尼日利亚阿布贾迈塔马904101 巴布科克大学微生物系尼日利亚奥贡州伊利山雷莫121103 纳萨拉瓦州立大学农业学院基础科学系化学组PMB 335 尼日利亚纳萨拉瓦州拉菲亚950101 纳萨拉瓦州立大学农业学院家庭科学系沙布拉菲亚校区PMB 335尼日利亚纳萨拉瓦州拉菲亚950101

采用LC-MS/MS真菌毒素检测法,对尼日利亚纳萨拉瓦州市场出售的食物作物(灌木芒果(n.12)、烤腰果(n.12)、干秋葵(n.12)、芝麻(n.35)、高粱(n.36))进行了分析研究。结果显示具致肝癌性黄曲霉毒素B1在灌木芒果、干秋葵和高粱样品中检出率... 详细信息

采用LC-MS/MS真菌毒素检测法,对尼日利亚纳萨拉瓦州市场出售的食物作物(灌木芒果(n.12)、烤腰果(n.12)、干秋葵(n.12)、芝麻(n.35)、高粱(n.36))进行了分析研究。结果显示具致肝癌性黄曲霉毒素B1在灌木芒果、干秋葵和高粱样品中检出率分别为42%、25%和19%,其平均浓度分别为19.2、8.27和4.75μg/kg,伏马毒素B1污染了9%的芝麻样品(平均浓度为12.5μg/kg)和47%的高粱样品(平均浓度为461μg/kg);同时受到黄曲霉毒素B1和伏马毒素B1污染的高粱样本至少有19%。灌木芒果、高粱和干秋葵中检测到了具致肾毒性的赭曲霉毒素A,这是首次在干秋葵中报道检测到该毒素。可见,当地市场出售的这些食物作物受到真菌毒素的污染,可能威胁消费者的健康,需要采取积极措施防控污染。

关键词：黄曲霉毒素B1 谷物坚果油籽食品安全真菌毒素公共卫生蔬菜