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Cancer Communications 2021年第11期41卷 1232-1233页

作者： Sang eun Yoon Won Seog kim Division of Hematology-oncology Department of MedicineSamsung Medical CenterSungkyunkwan University School of MedicineSeoul 06351Korea

Extranodal naturalkiller/T-cell lymphoma(ENKTL)is a distinct subtype of non-Hodgkin lymphoma(NHL)with aggressive clinical course and is closely associated with Epstein Barr virus(EBV)infection[1].Due to the unique feature that majority of ENKTL patients have involvement of the upper aerodigestive tract(UADT),the commonly used international prognostic index(IPI)system for NHL is not applicable for ENKTL as most of the patients would be divided into the low-risk group[2].Thus,an optimal prognostic system for ENKTL remains *** models particularly constructed for ENKTL have been reported and several potential risk factors such as regional lymph node involvement,nasal type disease,primary tumor invasiveness,and EBV-DNA,were identified as independent prognostic factors[3–5].

关键词： involvement killer lymphoma

Toward Data-Driven Digital Therapeutics Analytics:Literature Review and Research Directions

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IEEE/CAA Journal of Automatica Sinica 2023年第1期10卷 42-66页

作者： Uichin Lee Gyuwon Jung eun-Yeol Ma Jin San kim Heepyung kim Jumabek Alikhanov Youngtae Noh Heeyoung kim Korea Advanced Institute of Science and Technology Daejeon 34141Republic of Korea Inha University Incheon 402-751Republic of Korea KENTECH Naju-siRepublic of Korea

With the advent of digital therapeutics(DTx),the development of software as a medical device(SaMD)for mobile and wearable devices has gained significant attention in recent *** DTx evaluations,such as randomized clinical trials,mostly focus on verifying the effectiveness of DTx *** acquire a deeper understanding of DTx engagement and behavioral adherence,beyond efficacy,a large amount of contextual and interaction data from mobile and wearable devices during field deployment would be required for *** this work,the overall flow of the data-driven DTx analytics is reviewed to help researchers and practitioners to explore DTx datasets,to investigate contextual patterns associated with DTx usage,and to establish the(causal)relationship between DTx engagement and behavioral *** review of the key components of datadriven analytics provides novel research directions in the analysis of mobile sensor and interaction datasets,which helps to iteratively improve the receptivity of existing DTx.

关键词： Causal inference data-driven analytics framework digital therapeutics(DTx) mobile and wearable data technical and behavioral engagement

Experience of primary intestinal lymphangiectasia in adults: Twelve case series from a tertiary referral hospital

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World Journal of Clinical Cases 2024年第4期12卷 746-757页

作者： Ji eun Na Ji eun kim Sujin Park eun Ran kim Sung Noh Hong Young-Ho kim Dong Kyung Chang Department of Internal Medicine Inje University Haeundae Paik HospitalBusan 48108South Korea Department of Medicine Samsung Medical CenterSeoul 06351South Korea Department of Pathology Samsung Medical CenterSeoul 06351South Korea

BACKGROUND While primary intestinal lymphangiectasia(PIL)is considered a rare condition,there have been several reported cases in ***,the absence of clear guidance from diagnosis to treatment and prognosis poses challenges for both physicians and *** To enhance understanding by investigating clinical presentation,diagnosis,treatment,complications,and prognoses in adult PIL *** We enrolled adult patients diagnosed with PIL between March 2016 and September *** primary outcome involved examining the diagnosis and treatment process of these *** secondary outcomes included identifying complications(infections,thromboembolism)and assessing prognoses(frequency of hospitalization and mortality)during the follow-up *** Among the 12 included patients,peripheral edema(100%)and diarrhea(75%)were the main presenting *** tests showed that all the pati-ents exhibited symptoms of hypoalbuminemia and ***,the predominant findings were edema of the small intestine(67%)and ascites(58%).The typical endoscopic finding with a snowflake appearance was observed in 75%of *** the 12 patients,two responded positive-ly to octreotide and sirolimus,and eight who could undergo maintenance therapy discontinued *** due to PIL led to infection in half of the patients,thromboembolism in three patients,and one *** PIL can be diagnosed in adults across various age groups,with different severity and treatment responses among patients,leading to diverse complications and ***,tailored treatments will be *** anticipate that our findings will contribute to the management of PIL,an etiology of protein-losing enteropathy.

关键词： Primary intestinal lymphangiectasia in adults Protein-losing enteropathy Diagnosis Treatment Prognosis

Numerical modeling of sedimentation control scenarios in the approach channel of the Nakdong River Estuary Barrage,South Korea

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International Journal of Sediment Research 2016年第3期31卷 257-263页

作者： Un Ji eun-Kyung Jang Gwonhan kim Hydro Science and Engineering Research Institute Korea Institute of Civil Engineering and Building Technology

The effects of sedimentation reduction at the Nakdong River Estuary Barrage(NREB) in Korea were quantitatively analyzed with respect to different sediment control methods using the calibrated and validated two-dimensional *** countermeasures of sediment dredging,sediment flushing,channel geometry change,and a combination of flushing and channel geometry change were examined for the approach channel of the *** flood event and channel geometries of the 3.8 km section upstream of the NREB surveyed before and after dredging in 2007 were used for modeling *** a result,the half of sediments dredged in 2007 could be eliminated naturally by floods without *** numerical simulation of sediment flushing indicated that the deposition height decreased in the entire simulation section with the minimum and maximum reductions from 0.3 in to1.3 m in deposition *** channel contraction method produced quantitatively the largest amount of sedimentation reduction and sediment flushing and dredging *** reduction by a combination of flushing and channel contraction was up 10%compared to the individual method of channel contraction.

关键词： Channel contraction Nakdong River Estuary Barrage Sediment dredging Sediment flushing Sedimentation reduction

Increased incidence of chemoport-related thrombosis in patients with colorectal cancer receiving bevacizumab: A single-institutional experience

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Chinese Journal of Cancer Research 2018年第4期30卷 460-467页

作者： Jwa Hoon kim Jeong eun kim Yong Sang Hong Sun Young kim Kyu-pyo kim Ki eun Choi Ji Hoon Shin Tae Won kim Department of Oncology Asan Medical Center University of Ulsan College of Medicine Department of Radiology Asan Medical Center University of Ulsan College of Medicine

Objective： Chemoport-related thrombosis （CRT） is a serious complication that causes morbidities and interruptsadministration of intravenous cancer therapy. We investigated the incidence and risk of CRT in colorectal cancer（CRC） patients treated with bevacizumab （BEV）.Methods： We retrospectively reviewed 1,534 CRC patients who received chemotherapy with or without BEVusing a chemoport between 2014 and ***： The participants had a median age of 58 （18-85） years, and 60.3% were male. All participants werestratified into three groups： adjuvant chemotherapy （AC）（n=670）, palliative chemotherapy （PC） without BEV（n=356）, and PC with BEV （n=508）. The median follow-up was 20.19 （interquartile range, 14.07-27.19） *** occurred in 3.8% of all patients; incidence of symptomatic and asymptomatic CRT was 2.9% and 0.9%,respectively. CRT occurred more in patients with BEV （5.7%） than in patients without BEV （2.9%, P=0.008）. Thecumulative incidence of CRT in patients administered PC with BEV was significantly higher than that in thoseadministered AC （P=0.011） and there was a trend toward increased CRY in patients administered PC with BEVcompared with those administered PC without BEV （P=0.044）. Multivariate analysis found that BEV treatment wasthe only variable that was significandy associated with CRT （hazard ratio, 2.06; 95% confidence interval, 1.24-3.43;P=0.006）.Conclusions： BEV treatment was significandy associated with increased incidence of CRT in CRC patients.

关键词： Bevacizumab central venous catheters thrombosis colorectal neoplasms

Rheological,textural,and functional characteristics of 3D-printed cheesecake containing guava leaf,green tea,and barley sprout powders

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Food Bioscience 2022年第3期47卷 338-345页

作者： Ye-eun Park Jeong kim Hyun Woo kim Jiyeon Chun Department of Food Science and Technology Sunchon National UniversitySuncheon57922Republic of Korea Department of Biotechnology College of Life Science and BiotechnologyKorea UniversityAnam-dongSeongbuk-guSeoul02841Republic of Korea kimchi Science and Industrialization Institute Sunchon National UniversitySuncheon57922Republic of Korea

The use of 3D food printing as an alternative to manufacturing customized food is gaining *** this study,functional powders of guava leaf (GL),green tea (GT),and barley sprouts (BS) were tested as edible ink ingredients for printing cheesecake,and their physicochemical and functional properties were *** size and water and oil holding capacities were highest in GL powder,whereas the water-soluble index was highest in *** functional powder-added cheesecake,pseudoplastic and shear-thinning behavior was observed which is ideal for 3D *** shear modulus (1.87 kPa) of the control cheesecake (without functional powder) was significantly increased to 5 kPa or higher by adding functional *** in vitro glycemic index was lowest in GL cheesecake,whereas antioxidant activity and polyphenol content were highest in GT *** and GT powders would be beneficial as an edible ink to improve functional properties,such as antioxidant activity for GT and blood-glucose-lowering effect for BS,with enhanced printability and textural stability of 3D printed cheesecake.

关键词： 3D food print Guava Green tea Barley sprout Cheesecake

60 years of Rabinowicz' criterion for adhesive wear

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Friction 2018年第3期6卷 341-348页

作者： Elena POPOVA Valentin L.POPOV Dae-eun kim Institute of Mechanics Technische Universit?t Berlin School of Mechanical Engineering Yonsei University Center for Nano-Wear Yonsei University

60 years ago, in 1958, Ernest Rabinowicz published a 5 page paper titled "The effect of size on the looseness of wear fragments" where he suggested a criterion determining the minimum size of wear particles. The criterion of Rabinowicz is based on the consideration of the interplay of elastic energy stored in "asperities" and the work of separation needed for detaching a wear particle. He was probably the first researcher who explicitly emphasized the role of adhesion in friction and wear. In a recent paper in Nature Communications, Aghababaei, Warner and Molinari confirmed the criterion of Rabinowicz by means of quasi-molecular dynamics and illustrated the exact mechanism of the transition from plastic smoothing to formation of wear debris. This latter paper promoted the criterion of Rabinowicz to a new paradigm for current studies of adhesive wear. The size arguments of Rabinowicz can be applied in the same form also to many other problems, such as brittle-ductile transition during indentation, cutting of materials or ultimate strength of nano-composites.

关键词： adhesion plasticity wear Archard's law of wear Rabinowicz criterion surface topography history of Tribology

Polygonal multi-polymorphed Li4Ti5Oi2@rutile TiO2 as anodes in lithium-ion batteries

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Nano Research 2019年第4期12卷 897-904页

作者： Chang Hyun Hwang Hee-eun kim Inho Nam Jin Ho Bang Department ofBionano Technology Hanyang University 55 Hanyangdaehak-ro Sangnok-gu Ansan Gyeonggi-do 15588 Republic of Korea School of Chemical Engineering & Materials Science Chung-Ang University 84 Heukseok-ro Dongjak-gu Seoul 06974 Republic of Korea Department of Chemical and Molecular Engineering Hanyang University 55 Hanyangdaehak-ro Sangnok-gu Ansan Gyeonggi-do 15588 Republic of Korea

Li4Ti50i2 (LTO) has attracted considerable attention in lithium-ion battery (LIB) applications because of its favorable characteristics as an anode material. Despite its promise, the widespread use of LTO is still limited primarily due to its intrinsically poor electric and ionic con ductivities and high surface reactivity. To address these issues, we desig ned polyg onal nano architectures composed of various Li-Ti oxide crystal polymorphs by a facile synthesis route. Depending on the pH condition, this synthesis approach yields multi-polymorphed Li-Ti oxides where the interior is dominantly composed of a Li-rich phase and the exterior is a Li-deficient (or Li-free) phase. As one of these variations, a polygonal LTO-rutile TiO2 structure is formed. The rutile TiO2 on the surface of this LTO composite significantly improves the kinetics of Li^+ insertion/extraction because the channel along the o-axis in TQ2 provides a Li^+ highway due to the significantly low energy barrier for Li^+ diffusion. Moreover, the presenee of rutile TiO2, which is less reactive with a carbonate-based electrolyte, ensures Iong-term stability by suppress)ng the undesirable interfacial reaction on LTO.

关键词： micro-polygon structure Li-Ti oxide multi-polymorphs Li4Ti5Oi2@ rutile TiO2 anode lithium-ion batteries

Determination of efficient superfinishing conditions for mirror surface finishing of titanium

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Journal of Central South University 2012年第1期19卷 155-162页

作者： kim Jin-seob LIM eun-seong JUNG Yoon-gyo School of Mechatronics Changwon National UniversityChangwon 641-773Korea

To determine mirror surface finishing conditions and efficient and economical superfinishing conditions for pure titanium and titanium alloys, an abrasive film is used when superfinishing is performed under varying conditions. These conditions include the workpiece rotation speed, the oscillation speed, the contact pressure of the roller, the hardness of the roller, and the type of abrasive film. The superfinishing device is applied to polishing a thin and long cylindrical bar. A micro-finishing film and a lapping film were used as abrasive films. A1203 grains or SiC grains were used as abrasives. The surface roughness of a polished workpiece was measured using a stylus-type surface-roughness measuring instrument. As a result, the conditions to improve the polishing surface efficiently include high values for the workpiece rotation speed, oscillation speed and contact pressure. The roller hardness has no effect on the efficient polishing conditions. The mirror finish of a surface can be created using lapping film of 3 μm with Al2O3 grains after polishing to a steady surface roughness under the efficient polishing conditions.

关键词： superfinishing mirror surface finishing abrasive film surface roughness titanium optimal polishing time

The use of artificial nest boxes by Siberian flying squirrels (Pteromys volans) in South Korea

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Journal of Forestry Research 2019年第3期30卷 1131-1137页

作者： Jong-U kim Woo-shin Lee eun-Jae Lee Department of Forest Sciences Seoul National University Seoul 08826Republic of Korea Urban Planning Research Division Daejeon Sejong Research InstituteDaejeon 34863Republic of Korea

In this study, we examined the use of artificial nest boxes by Siberian flying squirrels (Pteromys volans) in three coniferous and mixed forests in Gangwon Province, South Korea. Six hundred and twelve boxes with different sized entry holes (ranging from 3 to 7 cm in diameter) were placed in the forests between 2004 and 2009. Pteromys volans used nine boxes in the coniferous forests and two boxes in the mixed forests. The squirrels only used boxes with entrance holes measuring 3.5, 4, and 5 cm in diameter, showing a strong and moderate preference for boxes with 5 and 4-cm holes, respectively, and a strong avoidance for boxes with 3- and 7-cm holes. Therefore, we suggest placing artificial nest boxes with entrance holes 5 cm in diameter to encourage breeding activity. Most nests made in the artificial boxes were composed of fibrous materials from woody vines. We recommend placing artificial nest boxes with holes of 5-cm diameter in coniferous forests, which support dense populations of P. volans, to survey whether this approach would positively affect the breeding habits and population maintenance of this species.

关键词： Artificial nest box Coniferous forests Nest materials Siberian flying squirrel Woody vines